BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0386.0008.p
         (185 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH2761 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex...    91   1e-18
BS_bfmBB [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase compl...    90   2e-18
SA1346 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex...    86   5e-17
lin1411 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple...    82   4e-16
BS_odhB [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple...    79   3e-15

>BH2761 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex,
          dihydrolipoamide acyltransferase (E2) component, and
          related enzymes
          Length = 553

 Score = 90.5 bits (223), Expect = 1e-18,   Method: Compositional matrix adjust.
 Identities = 5/71 (7%), Positives = 14/71 (19%)

Query: 8  TDVIMPQLAESLVSATIGKWLKQPGDAIEQYEPLCDLITDKVNAELPATVDGTLVELLAE 67
            + +  L   ++       L                               +  +L+ +
Sbjct: 3  NRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQ 62

Query: 68 EGQTVSVGEVI 78
              +S   V 
Sbjct: 63 TRINLSRSAVR 73


>BS_bfmBB [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex,
          dihydrolipoamide acyltransferase (E2) component, and
          related enzymes
          Length = 553

 Score = 89.7 bits (221), Expect = 2e-18,   Method: Compositional matrix adjust.
 Identities = 5/72 (6%), Positives = 15/72 (20%)

Query: 7  LTDVIMPQLAESLVSATIGKWLKQPGDAIEQYEPLCDLITDKVNAELPATVDGTLVELLA 66
              ++  L   L    + + +         +      +      E    +  T   +L 
Sbjct: 3  NRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQ 62

Query: 67 EEGQTVSVGEVI 78
                     +
Sbjct: 63 TRINLSRSAVRM 74


>SA1346 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex,
          dihydrolipoamide acyltransferase (E2) component, and
          related enzymes
          Length = 553

 Score = 85.5 bits (210), Expect = 5e-17,   Method: Compositional matrix adjust.
 Identities = 3/70 (4%), Positives = 17/70 (24%)

Query: 9  DVIMPQLAESLVSATIGKWLKQPGDAIEQYEPLCDLITDKVNAELPATVDGTLVELLAEE 68
             +  +   ++   +   L+    ++          +  V+ +L               
Sbjct: 2  INRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLML 61

Query: 69 GQTVSVGEVI 78
             +++    
Sbjct: 62 QTRINLSRSA 71


>lin1411 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex,
          dihydrolipoamide acyltransferase (E2) component, and
          related enzymes
          Length = 553

 Score = 82.0 bits (201), Expect = 4e-16,   Method: Compositional matrix adjust.
 Identities = 5/69 (7%), Positives = 15/69 (21%)

Query: 10 VIMPQLAESLVSATIGKWLKQPGDAIEQYEPLCDLITDKVNAELPATVDGTLVELLAEEG 69
           ++  L   L    + + +         +      +      E    +  T   +L    
Sbjct: 6  RVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRI 65

Query: 70 QTVSVGEVI 78
                  +
Sbjct: 66 NLSRSAVRM 74


>BS_odhB [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex,
          dihydrolipoamide acyltransferase (E2) component, and
          related enzymes
          Length = 301

 Score = 79.3 bits (194), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 3/72 (4%), Positives = 15/72 (20%)

Query: 7  LTDVIMPQLAESLVSATIGKWLKQPGDAIEQYEPLCDLITDKVNAELPATVDGTLVELLA 66
          ++         ++V              + Q   +           +         + + 
Sbjct: 1  MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIY 60

Query: 67 EEGQTVSVGEVI 78
           +   + + E  
Sbjct: 61 VDTPGLHMEEKR 72


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.131    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 8,333,420
Number of extensions: 258988
Number of successful extensions: 767
Number of sequences better than 1.0e-05: 61
Number of HSP's gapped: 762
Number of HSP's successfully gapped: 67
Length of query: 185
Length of database: 38,378,431
Length adjustment: 100
Effective length of query: 85
Effective length of database: 26,845,031
Effective search space: 2281827635
Effective search space used: 2281827635
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 112 (47.8 bits)