BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0385.0017.p (505 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 145 1e-34 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 137 4e-32 BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins 91 6e-18 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 84 7e-16 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 80 6e-15 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 145 bits (366), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 129/534 (24%), Positives = 247/534 (46%), Gaps = 78/534 (14%) Query: 1 VAGTALDGEEGLQMVREMKPDIVLTDIRMPRMDGLEMTRAILE-FAPHCKIIILSAYSEF 59 VA A +GE+ ++V+E+KPD+V+TDIRMP DGL++ + + E + + K II+S Y++F Sbjct: 30 VAAEADNGEDAFKLVQEIKPDLVITDIRMPVFDGLQLIQKVNETLSFNTKFIIISGYNDF 89 Query: 60 SYAQQAIRLGAMDFVKKPFSLEEIVNVVLKAKALCLQER---EEQEKIMAMQAQIKESLP 116 SYAQ+A+R GA+DFV KP +E+ ++K A QE+ +QEK++ Sbjct: 90 SYAQKAVRFGAVDFVLKPIDQDELEAALIKLAATLDQEKATNSDQEKVL----------- 138 Query: 117 ILRQEYLTFLMQHRTTEPSAKARWEYLGIPLAQKNFTVFIV-EIDHFAEKYGRQPVQEIE 175 L Q ++ L +++ + + RW + + ++F +++ E+++ + G Q E Sbjct: 139 -LDQIFIHSLGENK--KENEVRRWA-AKLNINNRHFYYYLLLEVNNLSLDKGFINEQYKE 194 Query: 176 LIRFSLQNILEETIHAWTQGVIFREATNRYVCIINGGDPHAAGLI--------------- 220 IR ++ ET+ + AT Y I D HA GL+ Sbjct: 195 PIR----KVIRETVAR-------QAATEEYTAIYEQLD-HAYGLLITSEHLKKFNGQIEP 242 Query: 221 -TEACCANVSRYSRCTVSIGVGLCVAAIHELADSYAQALSALAYHFYTGGNAVYSYASIV 279 E ++ ++ +++ VG + + SY A S Y + V+ + Sbjct: 243 LAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKYIFNEKNVF-----I 297 Query: 280 HKPRAASHYSVTAEQEFLFA-----LRSGNREKSRLVLQQIFDELLQLDPLPAPQYVENI 334 H+ + + LF + N ++ ++ +IF E +P+ + Sbjct: 298 HEQTESVDTTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSEFQTKKFVPSA-----V 352 Query: 335 GYELSFKICRVMLELFPYEKVQPLEQQVNQLKN--------RLHPSLQEIRSLLEGLCAE 386 ++ + +VM + VQ +E ++ + + + +++ + E Sbjct: 353 KTSVNRCVHKVM------QTVQAMEGDTGKIISAQAMTNWESYNLTFDQLKQVFTKFVLE 406 Query: 387 ACRWIEEERSVESTRIIQQAKAYICANLHTSLTLEQVAKQISLSQGYFSNLFKKVSGISF 446 A I+E R I + K YI + H +++L+ +A ++ Y LFKK G+ F Sbjct: 407 AAVIIQELRKENMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYF 466 Query: 447 QQFVMHEKMEKAKTMLIE-GMQVQEIAMELGYEHRRYFSEVFKKYTDMTPSEFK 499 +++++ +M +AK +L + M+V E+A +G+ YF F+K MTP+E++ Sbjct: 467 KEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYR 520 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 137 bits (345), Expect = 4e-32, Method: Compositional matrix adjust. Identities = 133/523 (25%), Positives = 250/523 (47%), Gaps = 57/523 (10%) Query: 2 AGTALDGEEGLQMVREMKPDIVLTDIRMPRMDGLEMTRAILEFAPHCKIIILSAYSEFSY 61 G A +G GL +VRE P IVLTDI MP M GL+M + + E +++ILS YSEF + Sbjct: 31 VGEAANGRRGLDIVRETSPHIVLTDIYMPIMYGLDMIQILREDGFDGEVVILSGYSEFEH 90 Query: 62 AQQAIRLGAMDFVKKPFSLEEIVNVVLKAKALCLQEREEQEK-IMAMQAQIKESLPILRQ 120 A++A++L D++ KP S++ I VLK L+E++ Q+ + + ++K P++ Sbjct: 91 ARKAMQLNITDYLSKPASVDTI-ETVLKRVINKLEEKQRQQGYLQELTNKVKRYEPLVET 149 Query: 121 EYLTFLMQHRTTEPSAKARWEYLGIPLAQKNFTVFIVEIDHFAEKYGRQPVQEIELIRFS 180 E++ L+ R E+L K+ + + + + L R+S Sbjct: 150 EWMKSLLTGRLRNGEIPE--EFLAKITKWKDQQHIACSLTYDGPQNKELKPADWYLFRYS 207 Query: 181 LQNILEETIHAWTQGVIFR----EATNRYVCI-ING--GDPHAAGLITE-ACCANVSRYS 232 + ++ E ++ + + FR +A +C+ +N +P + ++ E YS Sbjct: 208 VHKMIREVLNGYP--IDFRYLEMDAYRSALCLHVNKSVSEPVLSCMLMEIKDQVEQGIYS 265 Query: 233 RCTVSIGV--GLCVAAIHELADSYAQALSALAYHFYTGGNAVYSYASIVHKPRAASHYSV 290 V V G +L++S+ +A + + GN ++ + + + Sbjct: 266 SFNVKTTVHYGRVKEDWTDLSESFHEA--CMESQSFPLGNP--------YEDGTRATFPM 315 Query: 291 TAEQEFLFALRSGNREKSRLVLQQIFDELLQLDPLPAPQYVENIGYELSFKICRVML--- 347 + Q+ A+R + +++ VL++ L ++ Y +GY++ +I ++ Sbjct: 316 ESSQKLYDAIRYADATRAKEVLEEAVGVLGEV------PYSTLVGYKVGIEIWTIITYSL 369 Query: 348 --------ELF--PYEKVQPLEQQVNQLKNRLHPSLQE-IRSLLEGLCAEACRWIEEERS 396 E+F ++ Q L +Q N QE IR L E + C + + + Sbjct: 370 YDIGILIQEMFDEDFDLAQHLTKQGN---------WQEWIRFLCEQI-EHICYHQQWDEN 419 Query: 397 VESTRIIQQAKAYICANLHTSLTLEQVAKQISLSQGYFSNLFKKVSGISFQQFVMHEKME 456 ++ ++I+Q YI +L ++TL+ +A ++ +S+ Y +FKKV G SF+ +V +ME Sbjct: 420 IKHKQLIEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRME 479 Query: 457 KAKTMLIEG-MQVQEIAMELGYEHRRYFSEVFKKYTDMTPSEF 498 KAK M+ EG + E++ ++GY + YF+ +FKKYT TP + Sbjct: 480 KAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRDL 522 >BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 769 Score = 90.5 bits (223), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 101/410 (24%), Positives = 186/410 (45%), Gaps = 32/410 (7%) Query: 107 MQAQIKESLPILRQEYLTFLMQHRTTEPSAKARWEYLGIPLAQKNFTVFIVEIDHF-AEK 165 +Q QIK+ L+Q ++ L++ + + ++E P + V ++ID K Sbjct: 374 LQGQIKQ----LKQFFVLNLIKGHMSPSEIETKYETFQYPKDWRQLHVLTLQIDSLEGTK 429 Query: 166 YGRQPVQEIELIRFSLQNILEETI---HAWTQGVIFREATNRYVCIINGG---DPHAAGL 219 Y ++ E +++ FS+ N++E I T ++ N V I+ + G Sbjct: 430 YAKE---EKDVLLFSINNLVETLIPEVERLTPALL----NNTVVLILLTNVDQEQKRDGF 482 Query: 220 I---TEACCANVSRYSRCTVSIGVGLCVAAIHELADSYAQALSALAYHFYTGGNAVYSYA 276 + EA V + +VSIGV L I + ++Y + + AL Y G +V ++ Sbjct: 483 VREKAEAIMNEVRQQLDISVSIGVSLPYDDITKTQEAYDEGIEALKYRIKLGCQSVIFFS 542 Query: 277 SIVHKPRAASHYSVTAEQEFLFALRSGNREKSRLVLQQIFDELLQLDPLPAPQYVENIGY 336 ++ H ++Y E E AL+ G++ + L + D + Q D P+ QY ++ Sbjct: 543 NLAHTHSFHTYYPKQQENELFDALKLGDKSNVKDHLDALIDGIFQKDLHPS-QYQISLLR 601 Query: 337 ELSFKICRVMLELFPYEKVQPLEQQVNQLKNRLHPSLQEIRSL----LEGLCAEACRWIE 392 L+ I +L+ + V +++ L ++L SLQ I + L A + + Sbjct: 602 LLNNTIQ--LLQTLGIDSVDVYDKKT--LFDQLF-SLQTIDEVKQWFFTKLIAPSVHTVA 656 Query: 393 EERSVESTRIIQQAKAYICANLHTSLTLEQVAKQISLSQGYFSNLFKKVSGISFQQFVMH 452 E + I Q I LTLE +A+++ + Y S++F+K + ISF +++ Sbjct: 657 ERMDSQYRTISDQIIHIIQNEFDMELTLESIAERLHYNPNYLSSIFRKETNISFSEYLSS 716 Query: 453 EKMEKAKTMLIE-GMQVQEIAMELGYEHRRYFSEVFKKYTDMTPSEFKIS 501 ++ AK L+E M ++EIA L Y + + F FKK MTP +++ S Sbjct: 717 YRLAMAKKWLLETSMPIREIAERLCYGNSQNFIRSFKKKEGMTPGKYRQS 766 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 83.6 bits (205), Expect = 7e-16, Method: Compositional matrix adjust. Identities = 71/273 (26%), Positives = 127/273 (46%), Gaps = 14/273 (5%) Query: 234 CTVSIGVGLCVAAIHELADSYAQALSALAYHFYTGGNAVYSYASIVHKPRAASHYSVTAE 293 V GVG + +H + SY +AL AL Y A Y + K RA + E Sbjct: 259 AKVKTGVG-GIYRLHFFSTSYREALLALDI-IYDHKQASYYFYDKNVKIRADEQLPIERE 316 Query: 294 QEFLFALRSGNREKSRLVLQQIFDELLQLDPLPAPQYVENIGYELSFKICRVMLEL-FPY 352 + + A++SG+ EK+ +L+ P + + +L + R++ E+ + Sbjct: 317 NKLIEAIKSGDGEKALQAFDHYVQAILRCSKHPLHDMRKYLQ-QLFIILGRLLNEMGLHW 375 Query: 353 EKVQPLEQQVNQLKNRLHPSLQEIRSLLEGLCAEACRWIEEERSVESTRIIQQAKAYICA 412 E Q + ++ ++ + R ++E R+ + ++ A+ Y+ Sbjct: 376 ETAQDFAR---------FSTVHQVTEHGKSEILHIVRTLQEWRTTDEQSLMLLARDYVHD 426 Query: 413 NLHTSLTLEQVAKQISLSQGYFSNLFKKVSGISFQQFVMHEKMEKAKTML-IEGMQVQEI 471 + LTL+ +AK I LS Y S LFK+ ++F ++V ++E AK +L + ++EI Sbjct: 427 HFREPLTLDDLAKHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEI 486 Query: 472 AMELGYEHRRYFSEVFKKYTDMTPSEFKISYLG 504 E+GY+ YFS VFKK T +PS+++ S G Sbjct: 487 TYEIGYKDPNYFSRVFKKLTGKSPSDYRKSING 519 Score = 72.0 bits (175), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 32/127 (25%), Positives = 74/127 (58%) Query: 1 VAGTALDGEEGLQMVREMKPDIVLTDIRMPRMDGLEMTRAILEFAPHCKIIILSAYSEFS 60 + G A +G + ++ E +PD+++ DI+MP +DG++ + I + P + I++SA+ F Sbjct: 29 IVGEASNGRQAIEKALETQPDLMMMDIKMPGVDGVQAVKEIKQQLPETEFIMVSAFDTFE 88 Query: 61 YAQQAIRLGAMDFVKKPFSLEEIVNVVLKAKALCLQEREEQEKIMAMQAQIKESLPILRQ 120 YA++ +R G +++ KP + E+++ + + Q REE+ +Q ++++ ++ Sbjct: 89 YAREVMRYGVKEYLLKPTTKEDVLTALDRIVGEIEQAREEKNDQYKLQQRLEQISSFVQT 148 Query: 121 EYLTFLM 127 E + +L+ Sbjct: 149 ESILYLL 155 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 80.5 bits (197), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 36/102 (35%), Positives = 65/102 (63%), Gaps = 1/102 (0%) Query: 1 VAGTALDGEEGLQMVREMKPDIVLTDIRMPRMDGLEMTRAILEFAPHCKIIILSAYSEFS 60 + G A +G + +++++ PDI+LTDI MP ++G+++ + E P ++ L+ Y +F Sbjct: 31 IIGQAENGRQAWELIQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFD 90 Query: 61 YAQQAIRLGAMDFVKKPFSLEEIVNVVLKAK-ALCLQEREEQ 101 YA A++LG D++ KPFS ++I ++ K K L +E+EEQ Sbjct: 91 YALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQKLDKEEKEEQ 132 Score = 51.2 bits (121), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 27/85 (31%), Positives = 53/85 (62%), Gaps = 1/85 (1%) Query: 416 TSLTLEQVAKQISLSQGYFSNLFKKVSGISFQQFVMHEKMEKA-KTMLIEGMQVQEIAME 474 + +L+ +A + S Y S+L KK G+ FQ +++ E++++A +L +++ EIA + Sbjct: 156 SQFSLKSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEK 215 Query: 475 LGYEHRRYFSEVFKKYTDMTPSEFK 499 +G+E YF++ FK+ +TP +FK Sbjct: 216 VGFEDMNYFTQRFKQIAGVTPRQFK 240 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.322 0.135 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 33,884,678 Number of extensions: 1347333 Number of successful extensions: 5214 Number of sequences better than 1.0e-05: 313 Number of HSP's gapped: 6061 Number of HSP's successfully gapped: 322 Length of query: 505 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 394 Effective length of database: 25,576,357 Effective search space: 10077084658 Effective search space used: 10077084658 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 118 (50.1 bits)