BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0385.0008.p (517 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 170 7e-42 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 148 3e-35 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 131 3e-30 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 87 8e-17 BH3679 [T] COG4753 Response regulator containing CheY-like recei... 86 1e-16 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 170 bits (430), Expect = 7e-42, Method: Compositional matrix adjust. Identities = 142/537 (26%), Positives = 246/537 (45%), Gaps = 67/537 (12%) Query: 1 MSWEDQGIQVAGVSGNGEEGLKLITEVRPDLVITDIRMPRMDGLSMLRAVLED-NRSCKV 59 + WE G +VA + NGE+ KL+ E++PDLVITDIRMP DGL +++ V E + + K Sbjct: 21 IEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPVFDGLQLIQKVNETLSFNTKF 80 Query: 60 ILISGYADFEYAQQAVQLGAFDFVVKPFSEEDIMAAVLRAKAEIXXXXXXXXXXXXMEIK 119 I+ISGY DF YAQ+AV+ GA DFV+KP ++++ AA+++ A + Sbjct: 81 IIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKLAATLDQEKATNS-------- 132 Query: 120 LRESMPVLRQEYFTLLVSHRTSWEQAAGRWEFLNIELNPRGF-VVMLIEIDRFQEQVAEL 178 + VL + F + E RW + +N R F +L+E++ + Sbjct: 133 --DQEKVLLDQIFIHSLGENKK-ENEVRRWA-AKLNINNRHFYYYLLLEVNNLSLDKGFI 188 Query: 179 SIREVELIRFSLLNITQETIAEYAGCAVFRA-----RHNRYLAVMND-----TGPVSPIE 228 + + E IR + +ET+A A + A H L + ++ G + P Sbjct: 189 NEQYKEPIR----KVIRETVARQAATEEYTAIYEQLDHAYGLLITSEHLKKFNGQIEP-- 242 Query: 229 IAEQCCRNIERYTKFTVSVGVGGRVEETSELPDSYRQAHRALAH-HLFTEGNAAIMYDDL 287 +AE+ ++I+ +T ++V VG + ++ S + SY A+ + ++F E N I Sbjct: 243 LAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKYIFNEKNVFIH---- 298 Query: 288 HQTGSQEPLALEYKDELLLAL-RSGNAGRADAILSAIAETLHPLISRQNPDYLLSLYDEL 346 QT S + E + L + L +D I++ I + +++ Sbjct: 299 EQTESVDTTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSEFQTKK-----------F 347 Query: 347 AASAIRTFYELVPYRDIQPLIQKFRAVXXXXG---------------LPLASLQRQLLAL 391 SA++T R + ++Q +A+ G L L++ Sbjct: 348 VPSAVKTSVN----RCVHKVMQTVQAMEGDTGKIISAQAMTNWESYNLTFDQLKQVFTKF 403 Query: 392 CTEGAGLVRQNSLSEGQKVIYEAIDYIKSRLPEDITVGECAAHVHLSASYFSSLFKKVTG 451 E A ++++ + IY+ YI++ E+I++ A+ +++ Y LFKK G Sbjct: 404 VLEAAVIIQELRKENMKSDIYKVKTYIENHYHENISLKSIASLFYMNPVYMGQLFKKTFG 463 Query: 452 MTVTQFTTSERIQKAKALLVE-GAQVQEVASAVGYEERRYFSEMFKKITGQTPTEFR 507 + ++ R+ +AK LL + +V EVA VG+ YF F+KI TPTE+R Sbjct: 464 VYFKEYLLKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPTEYR 520 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 148 bits (373), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 140/535 (26%), Positives = 241/535 (45%), Gaps = 62/535 (11%) Query: 1 MSWEDQGIQVAGVSGNGEEGLKLITEVRPDLVITDIRMPRMDGLSMLRAVLEDNRSCKVI 60 +SW+ G + G + NG GL ++ E P +V+TDI MP M GL M++ + ED +V+ Sbjct: 21 ISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPIMYGLDMIQILREDGFDGEVV 80 Query: 61 LISGYADFEYAQQAVQLGAFDFVVKPFSEEDIMAAVLRAKAEIXXXXXXXXXXXXMEIKL 120 ++SGY++FE+A++A+QL D++ KP S + I + R ++ + K+ Sbjct: 81 ILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVINKLEEKQRQQGYLQELTNKV 140 Query: 121 RESMPVLRQEYFTLLVSHRTSWEQAAGRWEFLNIELNPRGFVVMLIEIDRFQE------- 173 + P++ E+ L++ R N E+ P F+ + + Q Sbjct: 141 KRYEPLVETEWMKSLLTGR-----------LRNGEI-PEEFLAKITKWKDQQHIACSLTY 188 Query: 174 ---QVAELSIREVELIRFSLLNITQETIAEYAGCAVFR----ARHNRYLAVMNDTGPVSP 226 Q EL + L R+S+ + +E + Y FR + L + + P Sbjct: 189 DGPQNKELKPADWYLFRYSVHKMIREVLNGYP--IDFRYLEMDAYRSALCLHVNKSVSEP 246 Query: 227 I------EIAEQCCRNIERYTKFTVSVGVG-GRV-EETSELPDSYRQAHRALAHHLFTEG 278 + EI +Q + I Y+ F V V GRV E+ ++L +S+ +A + F G Sbjct: 247 VLSCMLMEIKDQVEQGI--YSSFNVKTTVHYGRVKEDWTDLSESFHEA--CMESQSFPLG 302 Query: 279 NAAIMYDDLHQTGSQEPLALEYKDELLLALRSGNAGRADAILSAIAETLHPLISRQNPDY 338 N Y+D G++ +E +L A+R +A RA +L L + Y Sbjct: 303 NP---YED----GTRATFPMESSQKLYDAIRYADATRAKEVLEEAVGVLGEVPYSTLVGY 355 Query: 339 LLSLYDELAASAIRTFYELVPYRDIQPLIQKFRAVXXXXGLPL---ASLQRQLLALCTEG 395 + + E+ + Y DI LIQ+ L + Q + LC + Sbjct: 356 KVGI--EIWTIITYSLY------DIGILIQEMFDEDFDLAQHLTKQGNWQEWIRFLCEQI 407 Query: 396 AGLVRQNSLSEG---QKVIYEAIDYIKSRLPEDITVGECAAHVHLSASYFSSLFKKVTGM 452 + E +++I + + YI+ L E+IT+ + A +++S +Y +FKKV G Sbjct: 408 EHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGE 467 Query: 453 TVTQFTTSERIQKAKALLVEGA-QVQEVASAVGYEERRYFSEMFKKITGQTPTEF 506 + + T R++KAK ++ EG + EV+ VGY YF+ MFKK TG TP + Sbjct: 468 SFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRDL 522 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 131 bits (329), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 130/523 (24%), Positives = 245/523 (46%), Gaps = 56/523 (10%) Query: 7 GIQVAGVSGNGEEGLKLITEVRPDLVITDIRMPRMDGLSMLRAVLEDNRSCKVILISGYA 66 I + G + NG + ++ E +PDL++ DI+MP +DG+ ++ + + + I++S + Sbjct: 26 NIHIVGEASNGRQAIEKALETQPDLMMMDIKMPGVDGVQAVKEIKQQLPETEFIMVSAFD 85 Query: 67 DFEYAQQAVQLGAFDFVVKPFSEEDIMAAVLRAKAEIXXXXXXXXXXXXMEIKLRE-SMP 125 FEYA++ ++ G ++++KP ++ED++ A+ R EI ++ +L + S Sbjct: 86 TFEYAREVMRYGVKEYLLKPTTKEDVLTALDRIVGEIEQAREEKNDQYKLQQRLEQISSF 145 Query: 126 VLRQEYFTLLVSHRTSWEQAAGRW-EFLNIELNPRGFVVMLIEIDRFQEQVAELSIREVE 184 V + LL+ H +E W E+L E G+ V+ F +Q E IR+ E Sbjct: 146 VQTESILYLLMDHIQDYEWM--EWNEWLRTE--QEGYAVVF----SFHQQGKE--IRKTE 195 Query: 185 LIRFSLLNITQETIAEYAGCAV--FRARHNRYLAVMNDTGPVSPIE---IAEQCCRNIER 239 ++ I +E + V F H L + + ++ E + Q +++ Sbjct: 196 KQQWH-ARIKKEIGLQLPKSTVGPFIGHHLPILMLTENENGMTKQEREQVVIQLLHKVKQ 254 Query: 240 YTK-FTVSVGVGGRVEETSELPDSYRQAHRAL--------AHHLFTEGNAAIMYDDLHQT 290 + V GVGG + SYR+A AL A + F + N I D Sbjct: 255 AVQPAKVKTGVGG-IYRLHFFSTSYREALLALDIIYDHKQASYYFYDKNVKIRAD----- 308 Query: 291 GSQEPLALEYKDELLLALRSGNAGRA----DAILSAIAE-TLHPLISRQNPDYLLSLYDE 345 E L +E +++L+ A++SG+ +A D + AI + HPL + YL L+ Sbjct: 309 ---EQLPIERENKLIEAIKSGDGEKALQAFDHYVQAILRCSKHPLHDMRK--YLQQLFII 363 Query: 346 LAASAIRTFYELVPYRDIQPLIQKFRAVXXXXGLPLASLQRQLLALCTEGAGLVRQNSLS 405 L R E+ + + +F V + ++L + +++ + Sbjct: 364 LG----RLLNEMGLHWETAQDFARFSTVHQVT----EHGKSEILHIVR----TLQEWRTT 411 Query: 406 EGQKVIYEAIDYIKSRLPEDITVGECAAHVHLSASYFSSLFKKVTGMTVTQFTTSERIQK 465 + Q ++ A DY+ E +T+ + A H+ LS Y S LFK+ +T +++ T R++ Sbjct: 412 DEQSLMLLARDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEH 471 Query: 466 AKALL-VEGAQVQEVASAVGYEERRYFSEMFKKITGQTPTEFR 507 AK LL + ++E+ +GY++ YFS +FKK+TG++P+++R Sbjct: 472 AKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYR 514 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 86.7 bits (213), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 35/103 (33%), Positives = 68/103 (66%) Query: 1 MSWEDQGIQVAGVSGNGEEGLKLITEVRPDLVITDIRMPRMDGLSMLRAVLEDNRSCKVI 60 +SWE+ G +V + NG+EG ++ PDL+I DIRMP +DGLS++ ++ ++ + I Sbjct: 21 ISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPEVDGLSLIESIRAEDSAIHFI 80 Query: 61 LISGYADFEYAQQAVQLGAFDFVVKPFSEEDIMAAVLRAKAEI 103 ++SG++DF YA++A+ D+++KP E++++ ++ + I Sbjct: 81 ILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVYGRI 123 Score = 67.0 bits (162), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 65/267 (24%), Positives = 110/267 (41%), Gaps = 20/267 (7%) Query: 250 GGRVEETSELPDSYRQAHRALAHHLFTEGNAAIMYDDLHQTGSQEP--LALE-YKDELLL 306 G +V +++ +SY+ A R F E D L E +LE Y D L Sbjct: 240 GSKVVNLADIYESYQSAKRLYEKKFFVEKGRLFTADQLVDRSKPEAPEFSLESYADRLYY 299 Query: 307 ALRSGNAGRADAILSAIAETL--HPLISRQNPDYLLSLYDELAASAIRTFYELVPYRDIQ 364 ++ GN AI+ + + H ++ L LY + +R+ + ++ Sbjct: 300 SIDIGNMEGCVAIIEELKNVVIVHLQEEKEIKVALFQLYSNILHQLVRSHPNMEGV--LE 357 Query: 365 PLIQKFRAVXXXXGLP--LASLQRQLLALCTEGAGLVRQNSLSEGQK--VIYEAIDYIKS 420 PL+ + LP +A L +QL + + + GQ ++ + I I Sbjct: 358 PLVMNAGDIYQFEHLPGIMAFLTKQLKYVI---------DCMDNGQPDLLLRKMIALIHK 408 Query: 421 RLPEDITVGECAAHVHLSASYFSSLFKKVTGMTVTQFTTSERIQKAKALLVEGAQVQEVA 480 +++ + A+ + + +Y LFK TG + RI+ K LL +G +V EVA Sbjct: 409 DYAKNLRLETLASVFNYNRAYLGKLFKNYTGEYFNTYLDKVRIENGKRLLQKGYKVYEVA 468 Query: 481 SAVGYEERRYFSEMFKKITGQTPTEFR 507 +GY YF FKK G +P+ FR Sbjct: 469 EKIGYANVDYFHRKFKKYVGVSPSTFR 495 >BH3679 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 257 Score = 86.3 bits (212), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 41/100 (41%), Positives = 66/100 (66%), Gaps = 1/100 (1%) Query: 411 IYEAIDYIKSRLPEDITVGECAAHVHLSASYFSSLFKKVTGMTVTQFTTSERIQKAKALL 470 I+EA+ YI + L + I + + A VHL+ SY S+LFK+ T MT +++ T +R+Q AK LL Sbjct: 156 IHEALHYIDAHLDQKIGLKDVAKSVHLNPSYLSALFKEKTNMTFSEYLTRKRLQHAKHLL 215 Query: 471 VEGAQ-VQEVASAVGYEERRYFSEMFKKITGQTPTEFRAG 509 V + + ++A GY+ +YF ++FK+ G TPT++R G Sbjct: 216 VSTDRPISDIAEKCGYQTAKYFIKIFKEHEGMTPTQYRKG 255 Score = 74.3 bits (181), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 35/95 (36%), Positives = 59/95 (62%), Gaps = 1/95 (1%) Query: 2 SWEDQGIQVAGVSGNGEEGLKLITEVRPDLVITDIRMPRMDGLSMLRAVLEDNRSCKVIL 61 +W + + V + + +E + + E DL+ITDIRMP M GL +++A+ E N I+ Sbjct: 25 AWSPKLLNVQ-TAASAKEAITRLNEETIDLIITDIRMPEMSGLHLVKALQEQNPKPVCIV 83 Query: 62 ISGYADFEYAQQAVQLGAFDFVVKPFSEEDIMAAV 96 IS Y++FEYA A++LG +++KP +E ++ AV Sbjct: 84 ISAYSEFEYAHTALELGVRHYLLKPVKKEKLIEAV 118 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.135 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 34,926,015 Number of extensions: 1363088 Number of successful extensions: 5017 Number of sequences better than 1.0e-05: 278 Number of HSP's gapped: 5884 Number of HSP's successfully gapped: 288 Length of query: 517 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 406 Effective length of database: 25,576,357 Effective search space: 10384000942 Effective search space used: 10384000942 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)