BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0383.0017.p (303 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0395 [K] COG2378 Predicted transcriptional regulator 223 3e-58 lin0464 [K] COG2378 Predicted transcriptional regulator 168 1e-41 lin2535 [K] COG2378 Predicted transcriptional regulator 106 4e-23 BH1889 [K] COG2378 Predicted transcriptional regulator 84 3e-16 mlr3764 [K] COG2378 Predicted transcriptional regulator 73 4e-13 >lin0395 [K] COG2378 Predicted transcriptional regulator Length = 306 Score = 223 bits (568), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 117/304 (38%), Positives = 183/304 (60%), Gaps = 4/304 (1%) Query: 3 KVERLISIIMILLKKDIVPANEFAQLFHVSKRTILRDMETLSLSNIPIYSVNGVHGGYGI 62 K+ERLI IIM+LL++++V A+E A +F VSKRTI RD++TLS++NIPIY++ G GG GI Sbjct: 2 KIERLIGIIMLLLQRELVSASEMATMFEVSKRTIFRDIDTLSMANIPIYTIAGTKGGIGI 61 Query: 63 MDEYKVDKRLLSSPDLENILTALGGLEQILISEEVEVTIKKIEAMV--SPLSPKGSIELS 120 M YKVDK+LL++ DL I+ +L G+EQ+L S E + T++K++ M+ S PK SI L Sbjct: 62 MPTYKVDKKLLTADDLTAIIASLDGMEQLLSSAETKKTLQKMKNMLEHSSEPPKSSISLD 121 Query: 121 FYDWEGRAEILPTLKICQESILKRRLVSFDYIDKNGTTTNRIVEPYQLHFSETSWYLKGF 180 F + + E+ ++ +I K +LV YID+ G T R EPY L F SWYL+G+ Sbjct: 122 FSNLSMKKELNAKVESLYLAIKKHQLVELSYIDRTGNQTVRKTEPYHLLFRNRSWYLQGY 181 Query: 181 CLHRQGYRTFKLSRIDHLHMEGNSFNPRDYLVEQAHEASYQPQ--LAAIKALISPGIKDQ 238 L R +RTFK+SRI L +F R ++V+ +P + + ++ ++Q Sbjct: 182 SLERSDFRTFKMSRIVELKTLEETFEARPFVVKPFSMTGDRPTFLMHEVTLIVDKIAREQ 241 Query: 239 FIERYGRKSIENYSSDYFLATIHVPQNSIGFQFLASFGTDLEIVEPKTYVEEFRNYLIRM 298 +ER+ +I + ++FL + +P + G++FL GT + I + + F +YL + Sbjct: 242 IVERFDPVAISQHDEEHFLVKVTLPDHEAGYRFLLQLGTHVTIQNRDDFYDSFVDYLAEI 301 Query: 299 VEKY 302 KY Sbjct: 302 QGKY 305 >lin0464 [K] COG2378 Predicted transcriptional regulator Length = 310 Score = 168 bits (425), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 103/311 (33%), Positives = 166/311 (53%), Gaps = 15/311 (4%) Query: 3 KVERLISIIMILLKKDIVPANEFAQLFHVSKRTILRDMETLSLSNIPIYSVNGVHGGYGI 62 KV+RL+SI++ILL K+ + A E A F VS RTI RD++ + L+ +PI S GV GG+ I Sbjct: 2 KVDRLMSIVLILLDKERISAQELADRFEVSLRTIYRDIDAIDLAGVPIRSTPGVGGGFEI 61 Query: 63 MDEYKVDKRLLSSPDLENILTALGGLEQILISEEVEVTIKKIEAMVSPLSPKGSIEL--- 119 M +YK+D ++ S+ DL IL L L ++ +E+ + KI++ + P IEL Sbjct: 62 MPDYKMDSKVFSTADLSAILMGLSSLSNMVRGDELINALAKIKSFI-PADRAKEIELKAN 120 Query: 120 ----SFYDWEGRAEILPTLKICQESILKRRLVSFDYIDKNGTTTNRIVEPYQLHFSETSW 175 W G I P ++I + ++ + +L++F+YI G T RIVEPYQL + W Sbjct: 121 QIYIDLSQWTGNNNIQPHVEIIKVALQENKLLTFEYIAHQGNKTVRIVEPYQLVMKSSHW 180 Query: 176 YLKGFCLHRQGYRTFKLSRIDHLHMEGNSFNPRDYLVEQAHEASYQPQLAAIKALISPGI 235 YL G+C +R +R F+LSR+ L + ++F RD+ Q + + +A ++ I I Sbjct: 181 YLYGYCQNRNDFRLFRLSRMSGLQILEDTFTLRDF---QKPQLEMEDIVAIMQIEIKIRI 237 Query: 236 KDQFIER-YGRKSIENYSSD---YFLATIHVPQNSIGFQFLASFGTDLEIVEPKTYVEEF 291 I+R S EN+ D +++ + +N + L SFG E +EP E+ Sbjct: 238 HQSIIDRVLDYCSYENFYPDGEEHYIVSFPFIENEYHYDILLSFGDKCECLEPLHVREKM 297 Query: 292 RNYLIRMVEKY 302 + + +V Y Sbjct: 298 KRRIYDIVSIY 308 >lin2535 [K] COG2378 Predicted transcriptional regulator Length = 298 Score = 106 bits (265), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 78/299 (26%), Positives = 150/299 (50%), Gaps = 23/299 (7%) Query: 3 KVERLISIIMILLKKDIVPANEFAQLFHVSKRTILRDMETLSLSNIPIYSVNGVHGGYGI 62 K+ER+++I++++L++ ++ A+E A+ F VS RTI RDM+TL + P+ ++ G +GG+ + Sbjct: 2 KLERILAILVMILERKVL-ASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTM 60 Query: 63 MDEYKVDKRLLSSPDLENILTALGGLEQILISEEVEVTIKKIEAMVSPLSPKGSIELSFY 122 +D YK+ S + +L AL + ++++ E +KI + + I F+ Sbjct: 61 LDTYKLATFTFSEEEKRILLEALEARSEFMLNDSQETLREKITLLQTEKPTSNYI---FF 117 Query: 123 DWEGR------AEILPTLKICQESILKRRLVSFDYIDKNGTTTNRIVEPYQLHFSETSWY 176 D + AE+ + Q++ ++ + YI +GT TNR + P +L+ + SWY Sbjct: 118 DSATQHRKQIEAEVKRKIAYIQKAFTMKKQLDITYIAMDGTETNREISPQKLNLMDGSWY 177 Query: 177 LKGFCLHRQGYRTFKLSRIDHLHMEGNSFNPRDYLVEQAHEASYQPQLAAIKALISPGIK 236 L+ +C R R FKL+RI L + +E+ Q Q + ++ K Sbjct: 178 LEAYCHKRAAIRHFKLTRITSLKETSKT----SMKIEED-----QKQAEVTEKIVLEFPK 228 Query: 237 DQFIERYGRKSIENYSSDYFLATIHV---PQNSIGFQFLASFGTDLEIVEPKTYVEEFR 292 +Q + +E + L + P+ +I FL FG+ ++I+EP + +E++ Sbjct: 229 NQLGKLLDYFLLEEMQMELDLVRVRFQYDPERNI-IPFLLMFGSAVKILEPASLQKEYK 286 >BH1889 [K] COG2378 Predicted transcriptional regulator Length = 325 Score = 83.6 bits (205), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 72/323 (22%), Positives = 139/323 (43%), Gaps = 29/323 (8%) Query: 1 MDKVERLISIIMILLKKDIVPANEFAQLFHVSKRTILRDMETLSLSNIPIYSVNGVHGGY 60 M K +RL+ ++M++ +K E A+ F VS RTILRD++ LS +P+YS G HGGY Sbjct: 1 MSKAKRLMELMMVINRKRRFTVKELAEEFSVSSRTILRDLQELSELGVPLYSEVGPHGGY 60 Query: 61 GIMDEYKVDKRLLSSPDLENILTALGGLEQI----LISEEVEVTIKKIEAMVSPLSPKGS 116 +++E + + + I + L +E V K M + + Sbjct: 61 EVLNERVLPPIAFTEEEAVAIFFTVHALRHFSALPFQAESSSVNHKFYSYMPEDVKERID 120 Query: 117 IELSFYDWEG--RAEILPTLKICQESILKRRLVSFDYIDKNGTTTNRIVEPYQLHFSETS 174 + +D+E R P L ++ +K+ +VS +Y + + T R ++P ++ + Sbjct: 121 QLKNRFDFETPMRPLATPYLPTLLDAAIKQNVVSIEY-ETSQEKTKREIQPIGVYARDGF 179 Query: 175 WYLKGFCLHRQGYRTFKLSRIDHLHMEGNSFNPRDYLVEQAHEASYQPQLAAIKALISPG 234 WY +C R+ R F+ RI ++ E + NP ++ H ++Q + + ++ Sbjct: 180 WYCPSYCFLREDMRLFRCDRITYV-TEQTTNNPLNF--RHVHLGNWQSYMKQERNVL--- 233 Query: 235 IKDQFIERYGRKSIENYSSDYFLATIHVPQNSIGF--------------QFLASFGTDLE 280 D ++E + + +H+ Q+ G+ + FG D Sbjct: 234 --DFYVELSQDGVQRCVAEQWLKPHLHIRQDGSGWLEGPFPESEVPYFSYYFIGFGHDAT 291 Query: 281 IVEPKTYVEEFRNYLIRMVEKYS 303 + +P V + L ++ KY+ Sbjct: 292 VKQPVQLVTLIKKSLRELLSKYN 314 >mlr3764 [K] COG2378 Predicted transcriptional regulator Length = 239 Score = 73.2 bits (178), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 55/216 (25%), Positives = 95/216 (43%), Gaps = 15/216 (6%) Query: 1 MDKVERLISIIMILLKKDIVPANEFAQLFHVSKRTILRDMETLSLSNIPIYSVNGVHGGY 60 M + +RL I+ L +V A + VS+RTI RD+ L + +PI GV GY Sbjct: 1 MRRADRLFQIVQHLRGGRLVTAQKLGTWLEVSERTIYRDIADLQSTGVPIDGEAGV--GY 58 Query: 61 GIMDEYKVDKRLLSSPDL------ENILTALGGLEQILISEEVEVTIKKIEAMVSPLSPK 114 + + + + + + ++ ++ A GG ++E V I V P + K Sbjct: 59 MMREGFDLPPLMFTRDEIVALVAGARMVRAFGGAAMARAADEALVKI----GAVLPDTEK 114 Query: 115 GSI---ELSFYDWEGRAEILPTLKICQESILKRRLVSFDYIDKNGTTTNRIVEPYQLHFS 171 I E+ W + + + ++ KR++++ DY D+ G T R + P L F Sbjct: 115 DRIARTEIHTPMWVVSDAAREAIDLIERAVEKRQVLTIDYCDEAGRGTARDIRPLGLWFW 174 Query: 172 ETSWYLKGFCLHRQGYRTFKLSRIDHLHMEGNSFNP 207 W L +C R +R F++ RI + + G F P Sbjct: 175 GKVWTLVAWCEMRDDFRAFRIDRIASVVIAGRIFKP 210 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.138 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 22,146,565 Number of extensions: 947219 Number of successful extensions: 2276 Number of sequences better than 1.0e-05: 13 Number of HSP's gapped: 2265 Number of HSP's successfully gapped: 13 Length of query: 303 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 197 Effective length of database: 26,153,027 Effective search space: 5152146319 Effective search space used: 5152146319 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)