BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0383.0001.p (290 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2712 [K] COG0583 Transcriptional regulator 221 7e-58 cynR [K] COG0583 Transcriptional regulator 133 3e-31 sll0030 [K] COG0583 Transcriptional regulator 118 1e-26 AGc1597 [K] COG0583 Transcriptional regulator 110 3e-24 all0862 [K] COG0583 Transcriptional regulator 105 7e-23 >BH2712 [K] COG0583 Transcriptional regulator Length = 296 Score = 221 bits (564), Expect = 7e-58, Method: Compositional matrix adjust. Identities = 115/292 (39%), Positives = 176/292 (60%), Gaps = 10/292 (3%) Query: 3 INSEWYRIFLHAADCSNLTKAAQNLNMTQPSVSYAIKQLEEALGVRLFDRLSKGVRLTQE 62 +N E YR+F A + +KAA L +TQPSVS+AIKQLEE L V+LF R +KGV LT+E Sbjct: 1 MNLELYRVFYVTATEKSFSKAAAKLYITQPSVSHAIKQLEEMLEVQLFTRHAKGVELTKE 60 Query: 63 GQTLYLHVRQAFEELDSAERQMKNMQQYREGRLRIGANGAIIKDFIVPLLDQFHARYPNI 122 G+ +Y ++QA ++ AE+ ++ ++Q GR+ IG + + K F++P + +F ARYPNI Sbjct: 61 GEAIYPSIQQALGSINQAEQLLQELKQLEGGRVTIGGSDSTFKYFVLPSIQRFQARYPNI 120 Query: 123 RIQLSQEKTSLILERLKRGSLDLGYIYLPVSDEEIRIVASHASPFCA-----VVGTAFAD 177 I+L T I+E+L GS+D G+++LPV + + I PF VVG + Sbjct: 121 HIRLQHGSTPQIIEKLDNGSIDFGFVHLPVRERHVEI-----QPFLTISSLFVVGEQNRE 175 Query: 178 WSQQPLPTERLMELPLLMLSPGSTTRSFIEEWFRSQGIEAEADFELNSLEMLTEFAERGY 237 +++PLP E +++ PL+ S S++ F++ F QG+ + D E+ S+E+L E + G Sbjct: 176 LAERPLPLEEVLDYPLITFSESSSSTQFLQRLFERQGLHVQPDIEVGSVELLIECVKLGM 235 Query: 238 GAAFLPRAFVASRITGGSLVELHTAVPIPDRHIGIAVRKHSSLSLAAEAFLE 289 G AF+ + FV + G L+ L PI R IGI ++ LSLAA+ FLE Sbjct: 236 GVAFVTKDFVLRELEKGELMPLQMKEPIEQRAIGIVTKRGQPLSLAAKVFLE 287 >cynR [K] COG0583 Transcriptional regulator Length = 299 Score = 133 bits (334), Expect = 3e-31, Method: Compositional matrix adjust. Identities = 89/280 (31%), Positives = 142/280 (50%), Gaps = 3/280 (1%) Query: 11 FLHAADCSNLTKAAQNLNMTQPSVSYAIKQLEEALGVRLFDRLSKGVRLTQEGQTLYLHV 70 FL A+ + T+AA L+++QP++S I+QLEE+LGV LFDR + +RLT G+ + Sbjct: 9 FLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLGVPLFDRSGRTIRLTDAGEVWRQYA 68 Query: 71 RQAFEELDSAERQMKNMQQYREGRLRIGANGAIIKDFIVPLLDQFHARYPNIRIQLSQEK 130 +A +EL + +R + ++ G LRI FI PL+ F+ARYP+I +QL + Sbjct: 69 SRALQELGAGKRAIHDVADLTRGSLRIAVTPTFTSYFIGPLMADFYARYPSITLQLQEMS 128 Query: 131 TSLILERLKRGSLDLGYIYLPVSDEEIRIVASHASPFCAVVGTAFADWSQQPLPTERLME 190 I + L R LD+G + PV E+ + VV + + RL + Sbjct: 129 QEKIEDMLCRDELDVGIAFAPVHSPELEAIPLLTESLALVVAQHHPLAVHEQVALSRLHD 188 Query: 191 LPLLMLSPGSTTRSFIEEWFRSQGIEAEADFELNSLEMLTEFAERGYGAAFLPRAFVASR 250 L++LS TR I+ + G+ + E NS+ + E R + LP A +A++ Sbjct: 189 EKLVLLSAEFATREQIDHYCEKAGLHPQVVIEANSISAVLELIRRTSLSTLLPAA-IATQ 247 Query: 251 ITGGSLVELHTAVPIPDRHIGIAVRKHSSLSLAAEAFLEM 290 G + L A P+ +R + RK+S + AA+AFL M Sbjct: 248 HDGLKAISL--APPLLERTAVLLRRKNSWQTAAAKAFLHM 285 >sll0030 [K] COG0583 Transcriptional regulator Length = 304 Score = 118 bits (295), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 83/282 (29%), Positives = 138/282 (48%), Gaps = 1/282 (0%) Query: 8 YRIFLHAADCSNLTKAAQNLNMTQPSVSYAIKQLEEALGVRLFDRLSKGVRLTQEGQTLY 67 + +F A + TKAA+ L +TQP+VS +KQL +A+GV L++++ + + LT+ GQ + Sbjct: 9 FEVFAAIARTGSFTKAAEELFLTQPTVSQQMKQLTKAIGVPLYEQIGRKIYLTEAGQAVL 68 Query: 68 LHVRQAFEELDSAERQMKNMQQYREGRLRIGANGAIIKDFIVPLLDQFHARYPNIRIQLS 127 + LD + + ++Q ++G LR+ A K F+ LL +F +YP I I L Sbjct: 69 DASKNITSCLDQLQEVIADLQGLKKGNLRL-ATITTGKYFVPRLLGEFRQQYPGISISLQ 127 Query: 128 QEKTSLILERLKRGSLDLGYIYLPVSDEEIRIVASHASPFCAVVGTAFADWSQQPLPTER 187 ILERL DL ++ P S+ +I I +P + ++ + ER Sbjct: 128 IGNRQQILERLANNLDDLYFLGKPPSNLDINIRHFLENPLVVIASRQHPLVKEKKISLER 187 Query: 188 LMELPLLMLSPGSTTRSFIEEWFRSQGIEAEADFELNSLEMLTEFAERGYGAAFLPRAFV 247 L+ PL+M GS TR +EE+F ++ + E++S E + + G G + L + Sbjct: 188 LVNEPLIMRESGSGTRMAVEEFFSENRLKMNVEMEISSNEAIKQAVYGGLGISILSLYSL 247 Query: 248 ASRITGGSLVELHTAVPIPDRHIGIAVRKHSSLSLAAEAFLE 289 A G L L +H I +K LS+ A+ FL+ Sbjct: 248 ALEGINGPLAVLDVEGFPLQKHWYIIYQKSKQLSIVAQTFLD 289 >AGc1597 [K] COG0583 Transcriptional regulator Length = 370 Score = 110 bits (274), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 17/274 (6%), Positives = 44/274 (16%), Gaps = 3/274 (1%) Query: 8 YRIFLHAADCSNLTKAAQNLNMTQPSVSYAIKQLEEALGVRLFDRLSKGVRLTQEGQTLY 67 L + + VS + R + Sbjct: 30 MATILSHLRNAKPYRTGALGITAAELVSLLELAERGQVNSPEQARQFFETNSVPFRISPA 89 Query: 68 LHVRQAFEELDSAERQMKNMQQYREGRLRIGANGAIIKDFIVPLLDQFHARYPNIRIQLS 127 E ++ ++ D F Y + Sbjct: 90 QGKSGFVTAFYEPELEVSATPDDVWRYPIYRRPPELVDIDNDNRPDGFDPSYAFGKADEE 149 Query: 128 QEKTSLILERLKRGSLDLGYIYLPVSDEEIRIVASHASPFCAVVGTAFADWSQQPLPTER 187 + G L + + + ++ + H +V + + Sbjct: 150 GISYFPDRRAIDEGCLRGRGLEIAWARSKVDLFFVHVQGAARLVFPD-GAIKRITYAAKA 208 Query: 188 LMELPLLMLSPGSTTRSFIEEWFRSQGIEAEADFELNSLEMLTEFAERGYGAAFLPRAFV 247 + + Q I + ++ + A + Sbjct: 209 GHVFSPI-GRLLLDRGELDPKTISMQTIRQWLADHPDEVDGVLWHNRSYIFFREADVAGL 267 Query: 248 ASRITGGSLVELHTAVPIPDRHIGIAVRKHSSLS 281 + A I Sbjct: 268 DMG-PIAAAKVPLVAGRALAVDRLIHTFGLPFFI 300 >all0862 [K] COG0583 Transcriptional regulator Length = 306 Score = 105 bits (262), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 77/240 (32%), Positives = 121/240 (50%), Gaps = 11/240 (4%) Query: 10 IFLHAADCSNLTKAAQNLNMTQPSVSYAIKQLEEALGVRLFDRLSKGVRLTQEGQTLYLH 69 +F AA + T+AA+ L +TQP+VS IKQL +++G+ LF+++ K + LT+ G+ L+ Sbjct: 1 MFEAAARHGSFTRAAEELFLTQPTVSMQIKQLTKSVGLPLFEQVGKRLYLTEAGRELFAT 60 Query: 70 VRQAFEELDSAERQMKNMQQYREGRLRIGANGAIIKDFIVPLLDQFHARYPNIRIQLSQE 129 RQ FE + E ++ +++ ++G+LR+ A K FI LL F YP I I L Sbjct: 61 CRQIFETIAQFEMKVADLKGLKQGQLRL-AVITTAKYFIPRLLGPFCQLYPGIDISLQVT 119 Query: 130 KTSLILERLKRGSLDLGYIYLPVSDEEIRIVASHASPFCAVVGTAFADWS-----QQPLP 184 ILER+ DL YI V + + + PF FA + ++ +P Sbjct: 120 NHERILERMMSNMDDL-YIMSQVPEH----LDVTSQPFLDNPLVVFAPANHPLAQEKNIP 174 Query: 185 TERLMELPLLMLSPGSTTRSFIEEWFRSQGIEAEADFELNSLEMLTEFAERGYGAAFLPR 244 +RL P +M PGS TR ++ QG+ + EL S E + + G G + L R Sbjct: 175 IQRLSSEPFIMREPGSGTRRAVQNLLEEQGVSVKVKLELGSNEAIKQAIAGGLGISVLSR 234 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.135 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,271,923 Number of extensions: 832633 Number of successful extensions: 5869 Number of sequences better than 1.0e-05: 1552 Number of HSP's gapped: 3060 Number of HSP's successfully gapped: 1552 Length of query: 290 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 185 Effective length of database: 26,268,361 Effective search space: 4859646785 Effective search space used: 4859646785 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 115 (48.9 bits)