BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0032.p (2444 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ppsA_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 776 0.0 all2644_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 763 0.0 all2643 [Q] COG1020 Non-ribosomal peptide synthetase modules and... 619 e-176 AGl2309_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 578 e-164 RSp0641_7 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 532 e-150 >BS_ppsA_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 792 Score = 776 bits (2003), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1215 (0%), Positives = 0/1215 (0%), Gaps = 45/1215 (3%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLDYGLGPNEEQAKVKLIEPMAE 60 + P Y ++ + + Sbjct: 310 EKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQVMERYT-LHSQGKIIAEGRAIGHR 368 Query: 61 VAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDM 120 + + + + N + + + + + ++ Sbjct: 369 IGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARE 428 Query: 121 LSNQEKHLLLNVFKGTPTDYP-KDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQA 179 L + + + + + L Sbjct: 429 LGIPAVVGCGDATERMKDGENVTVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMM 488 Query: 180 NSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTD 239 N G+ R +I ++G + I M+ Sbjct: 489 NVGNPDRAFDF-ACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKG 547 Query: 240 SQAAMLLFQHHIVKDLTYAGGRLELENSELYIRETG-------NPVKASLPENLAYVIYT 292 + + + + + G + I + Sbjct: 548 FDSPREFYVGRLTEGIATLG---AAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPM 604 Query: 293 SGTTGTPKGVMVEHRNLVNY-IHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGN 351 G G + V R+ + T + + ++ Sbjct: 605 LGFRGAGRYVSDSFRDCFALECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQ 664 Query: 352 TIVIYDGEDKALLTR--TIAEENKVNIVKLTPTH----LRLLEDMDLSRSSIRTFIVGGE 405 + + K ++ ++ + + + Sbjct: 665 GLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFD 724 Query: 406 DLKIKVAEKIHRAFDGRIEIYNEYGPTEATVGCMIYKYNAERD-KGTSVSIGIPADNTQL 464 + V + A + G + S+S+ Sbjct: 725 ERNDAVKALLSMAIRAAKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTW 784 Query: 465 YIVGSRMELLPVGVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSKLYKTGDMARW 524 Sbjct: 785 844 Query: 525 LSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVV 584 Sbjct: 845 904 Query: 585 SNKEVIASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYE 644 Sbjct: 905 --- 961 Query: 645 APNNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQ 704 Sbjct: 962 1021 Query: 705 YPSIKELAGYVKHEDVQAPQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLD 764 Sbjct: 1022 1081 Query: 765 EEILRKAVVAILVHHDALRMVYKRTPDG-ITQWNRSADCAGAA-FTLDVYDLRGQDEKRS 822 Sbjct: 1082 1141 Query: 823 -----IPALSDELQKGLDLEEGLLVKLGLFKTSLGDHLLVAVHHLVIDGVSWRILIADLE 877 Sbjct: 1142 1201 Query: 878 TAYRNIAAGAAASLPPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFG 937 Sbjct: 1202 - 1260 Query: 938 EENRGCGERME---VSLNFSKEQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQL 994 Sbjct: 1261 - 1319 Query: 995 LVSLEGHGREEIFQGVSIDRTIGWFTTIFPVVLDM----TRSHDLAYSLKRTKEMLRHVP 1050 Sbjct: 1320 1379 Query: 1051 HKGIGYGIWKYLADGNKELRAFEPEVSFNYLGEFGREAGSSLLEFSRLSSGASISIDNNK 1110 Sbjct: 1380 ---- 1435 Query: 1111 LKGIDINGLIMEGELELVFSYSTLEYTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPW 1170 Sbjct: 1436 - 1494 Query: 1171 DYGDPDLSLEDLDTL 1185 Sbjct: 1495 1509 Score = 461 bits (1186), Expect = e-129, Method: Compositional matrix adjust. Identities = 0/1065 (0%), Positives = 0/1065 (0%), Gaps = 65/1065 (6%) Query: 1191 EIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILR 1250 L + N + G + + V + N + L Sbjct: 2 SNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLD 61 Query: 1251 TAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLL 1310 + I + + ++ R + + + ++ Sbjct: 62 QSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQ--------PELENAIREAYA 113 Query: 1311 RVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDYL 1370 +++ + + + D AG + Q + A ++ Sbjct: 114 QLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVA-----VKHVFASLF 168 Query: 1371 DWLDHQDKAAALD----YWQSYLEAYESGTVIPELQHQE--KGFMHQQERTSLDAQATAK 1424 + + S + + + + + Sbjct: 169 NDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLG 228 Query: 1425 LKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTV 1484 + A V + + P+ + + V + Sbjct: 229 EMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPT--QEHGKQVKIEDVPQ 286 Query: 1485 PVRVTGGDQLSFIALAKKLNKDFIHA---NAFSFCQLAEIQALSP--MKNNLINHVVVYE 1539 R + K Sbjct: 287 EQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQV 346 Query: 1540 NYPVDQSLADLQEAEGREVKITAAQGFEQTN-YDLEILIAP-GRTLQIKITYNGCKYSRD 1597 ++ + ++++ + Sbjct: 347 M-------ERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDP 399 Query: 1598 VINALMDNLMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYA-KEKTIAQLF 1656 +M +++ AA + Sbjct: 400 DWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENVTVSCAEGDT 459 Query: 1657 EEQAERTPEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVG 1716 E + L N + + R ++ Sbjct: 460 GYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRA-FDFACLPNEGVGLARLEFIINR 518 Query: 1717 ILGILKAGGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLA-----APLGLNEAVTILD 1771 ++G+ + I M++ + L I+ Sbjct: 519 MIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATLGAAFYPKRVIVR 578 Query: 1772 IGSKQIQDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKG-ITDRISF 1830 + + ++ + + G G + V+ R + Sbjct: 579 LSDFK---SNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFR---DCFALECEAVKRV 632 Query: 1831 TEDKI---ILSVTTCSFDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTI 1887 D + + + ++++ + + + Sbjct: 633 RNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIPSNALLAEQFL 692 Query: 1888 QLTPSRL-KLMLNCSNTAESFKKLKLMMIGGEGF-PKDLLVQLQKFTDS-RIYNMYGPTE 1944 + + ++ + + + + G Sbjct: 693 EYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRAAKKQGKYVGICG 752 Query: 1945 TTIWSTVKELTHE-----NSVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARG 1999 Sbjct: 753 QGPSDHEDFAAWLMEEGI 812 Query: 2000 YLHKEELTASKFVDNPFMQGTKMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEI 2059 Sbjct: 813 872 Query: 2060 ESVAARHDKITQCVVAGQPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYI 2119 Sbjct: 873 - 931 Query: 2120 QIDEIPLTANGKTNLKALPKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYD 2179 Sbjct: 932 --- 988 Query: 2180 NFFEVGGNSLKIVAMYNELQKLYPGKIQITDIFSYPTISRLAQFI 2224 Sbjct: 989 - 1032 Score = 55.5 bits (132), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 0/328 (0%), Positives = 0/328 (0%), Gaps = 40/328 (12%) Query: 1198 LSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFY-- 1255 Sbjct: 1050 -- 1107 Query: 1256 --HDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDR--SNPFDLEQDCLLR 1311 Sbjct: 1108 1167 Query: 1312 VAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELK-QEKAVPYSDYL 1370 Sbjct: 1168 - 1226 Query: 1371 DWLDHQDKAAAL----DYWQSYLEAYESGTVIPELQHQEKGFMHQQERTSLDAQATAKLK 1426 Sbjct: 1227 -------- 1278 Query: 1427 S----------LAEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIE-- 1474 Sbjct: 1279 1338 Query: 1475 RMVGLCINTVPVRVTGG------DQLSF 1496 Sbjct: 1339 1366 >all2644_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 763 bits (1970), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1240 (0%), Positives = 0/1240 (0%), Gaps = 75/1240 (6%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENL---DYGLGPNEEQAKVKLIEP 57 Sbjct: 321 ---- 376 Query: 58 MAEVAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGG 117 Sbjct: 377 436 Query: 118 LDMLSNQEKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNE 177 Sbjct: 437 -- 494 Query: 178 QANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYML 237 Sbjct: 495 554 Query: 238 TDSQAAMLLFQHHIVKDLTYAGGRLELENSEL---YIRETGNPVKASLPENLAYVIYTSG 294 Sbjct: 555 ---- 610 Query: 295 TTGTPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIV 354 Sbjct: 611 670 Query: 355 IYDGEDKALLTRTIAEENKVNIVKLTPTHLRLLEDMDLSRSSIRTFIVGGEDLKIKVAEK 414 Sbjct: 671 --- 727 Query: 415 IHRAFDGRIE-IYNEYGPTEATVGCMIYKYNA--ERDKGTSVSIGIPADNTQLYIVGSRM 471 Sbjct: 728 ------ 781 Query: 472 ELLPVGVAGELCIGGDGVARGYLHKEALTAEKF-----VDHPFNAGSKLYKTGDMARWLS 526 Sbjct: 782 841 Query: 527 DGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSN 586 Sbjct: 842 901 Query: 587 KEVIASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAP 646 Sbjct: 902 -- 959 Query: 647 NNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYP 706 Sbjct: 960 1019 Query: 707 SIKELAGYVKHE-DVQAPQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLDE 765 Sbjct: 1020 1079 Query: 766 EILRKAVVAILVHHDALRMVYKRTPDGITQW----NRSADCAGAAFTLDVYDLRGQ---- 817 Sbjct: 1080 1139 Query: 818 -----------------------DEKRS--IPALSDELQKGLDLEEGLLVKLGLFKT--S 850 Sbjct: 1140 1199 Query: 851 LGDHLLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTASYRSWAQKLKEYAS 910 Sbjct: 1200 1259 Query: 911 GKVLLKEAEYWKGITNTGSGPLPKDFGEENRGCGERMEVSLNFSKEQTAKLLRNCNTAYN 970 Sbjct: 1260 1319 Query: 971 TQINDVLLCSLGLAFKEWGGMDQLLVSLEGHGREEIFQGVSIDRTIGWFTTIFPVVLDMT 1030 Sbjct: 1320 1379 Query: 1031 RSHDLAYSLKRTKEMLRHVPHKGIGYGIWKYLADGN--KELRAFE-PEVSFNYLGEFGR- 1086 Sbjct: 1380 1439 Query: 1087 EAGSSLLEFSRLSSGASISIDNNKLKGIDINGLIMEGELELVFSYSTLEYTRETVAQLTA 1146 Sbjct: 1440 1499 Query: 1147 AYHTSLLQVIDHCAHRQTAEKTPWDYGDPDLSLEDLDTLL 1186 Sbjct: 1500 1539 Score = 426 bits (1095), Expect = e-118, Method: Compositional matrix adjust. Identities = 0/1052 (0%), Positives = 0/1052 (0%), Gaps = 75/1052 (7%) Query: 1224 LNIEGYLNVEILNMVLNELTGKYEILRTAFFYHDIKKFKQAVLKERKL---RIHYEDISS 1280 Y + +N++ + K Sbjct: 33 HAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE----TYVGNWLAKHGSREKLIIASKV 88 Query: 1281 RSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKTDTGNFKVVYSFHHIIMDGWSAGI 1340 + + + ++V + G Sbjct: 89 SGPSRNNDKGIRPDQALDRKNIREA-LHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYS 147 Query: 1341 ILQEVIAQYKARL--QEAELKQEKAVPYSDYL----DWLDHQDKAAALDYWQSYLEAYES 1394 A AE ++ + Y + A + Sbjct: 148 WTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVT---I 204 Query: 1395 GTVIPELQHQEKGFMHQQERTS-----LDAQATAKLKSLAEANGITLSSVIQTAWGVVLQ 1449 L + + + + + + NG + T + + Sbjct: 205 QNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTR 264 Query: 1450 KYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRVTGGDQLSFIALAKKLNKDFIH 1509 + V G++ L + + Sbjct: 265 YSGEQTQKAVAAYVDIA--RRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESL 322 Query: 1510 ANA---FSFCQLAEIQALSPMKN----NLINHVVVYENYPVDQSLADLQEAEGREVKITA 1562 ++ + Sbjct: 323 HLELSEDVLAEIEAV--HQVYTY-- 378 Query: 1563 AQGFEQTNYDLEILIA-PGRTLQIKITYNGCKYSRDVINALMDNLMHVLSCAVSNPDQAA 1621 Sbjct: 379 ---- 434 Query: 1622 ESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEAIALEFHGTVLSYREL 1681 Sbjct: 435 -- 492 Query: 1682 NKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPLDTDYPVDRIHY 1741 Sbjct: 493 552 Query: 1742 MLQDSQASLLLTE-KGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQSITKADDLAYVLYT 1800 Sbjct: 553 ---- 608 Query: 1801 SGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDKIILSVTTCSFDIFGLESLLPLTRGLK 1860 Sbjct: 609 668 Query: 1861 VVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAESFKKLKLMMIGGEGF 1920 Sbjct: 669 -------- 720 Query: 1921 PKDLLVQL-QKFTDSRIYNMYGPTETTIWSTVKELTHENS---VNVGKPIANTQVYIVDQ 1976 Sbjct: 721 - 779 Query: 1977 AGHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTK-----MYTTGDLARW 2031 Sbjct: 780 839 Query: 2032 LPNGELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQDLVLYFV 2091 Sbjct: 840 899 Query: 2092 AAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRPELRDDY 2151 Sbjct: 900 - 958 Query: 2152 EEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNS---LKIVAMYNELQKLYPGKIQI 2208 Sbjct: 959 ------ 1012 Query: 2209 TDIFSYPTISRLAQFIDNQSAFAEAAVALDHE 2240 Sbjct: 1013 1044 >all2643 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 619 bits (1596), Expect = e-176, Method: Compositional matrix adjust. Identities = 0/1082 (0%), Positives = 0/1082 (0%), Gaps = 59/1082 (5%) Query: 1190 QEIEKIHSLSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEIL 1249 ++ +L + I E+ + T Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 1250 RTAFFYHDIKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCL 1309 + ++ ++ + + + + S Sbjct: 68 YVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLD 127 Query: 1310 LRVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKARLQEAELKQEKAVPYSDY 1369 L N + + + + +A+Y+ A + V Sbjct: 128 LYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQ----RAGKIRYIGVSNETA 183 Query: 1370 LDWLDHQDKAAALDYWQSYLEAYESGTVIPELQHQEKGFMHQQERT-SLDAQATAKLKSL 1428 + + A D + + + + + + Sbjct: 184 FGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTG 243 Query: 1429 AEANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRPSDIKGIERMVGLCINTVPVRV 1488 NG + T + + + V +M + P Sbjct: 244 KYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVA 303 Query: 1489 TGGDQLSFIALAKKLNKDFIHANAFSFCQLAEIQALSPMK--NNLINHVVVYENYPVDQS 1546 + + + K + + E Sbjct: 304 STLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTYPA 363 Query: 1547 LADLQEAEGREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINALMDNL 1606 Sbjct: 364 ---- 419 Query: 1607 MHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIAQLFEEQAERTPEA 1666 Sbjct: 420 --- 476 Query: 1667 IALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGG 1726 Sbjct: 477 536 Query: 1727 YLPLDTDYPVDRIHYMLQDSQASLLLTEKGL-----------AAPLGLNEAVTI-LDIGS 1774 Sbjct: 537 596 Query: 1775 KQIQDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTEDK 1834 Sbjct: 597 656 Query: 1835 IILSVTTCSFDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSRL 1894 Sbjct: 657 716 Query: 1895 KLMLNCSNTAESFKKLKLMMIGGEGFPKDLLVQLQKFTDSRIYNMYGPTETTI---WSTV 1951 Sbjct: 717 776 Query: 1952 KELTHENSVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTASKF 2011 Sbjct: 777 836 Query: 2012 V---------------DNPFMQG---------TKMYTTGDLARWLPNGELDVIGRLDNQV 2047 Sbjct: 837 896 Query: 2048 KIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQDLVLYFVAAEKI-----STSELV 2102 Sbjct: 897 956 Query: 2103 NFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRPELRDDYEEAVTDLQKEI 2162 Sbjct: 957 - 1015 Query: 2163 QQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNELQKLYPGKIQITDIFSYPTISRLAQ 2222 Sbjct: 1016 1075 Query: 2223 FI 2224 Sbjct: 1076 1077 Score = 414 bits (1063), Expect = e-114, Method: Compositional matrix adjust. Identities = 0/741 (0%), Positives = 0/741 (0%), Gaps = 71/741 (9%) Query: 29 LFDVMFVLENLDYGLGPNEEQAKVKLIEPMA-EVAKFDLTLTAKEAGGNLDFSLEYSSRL 87 Sbjct: 348 - 406 Query: 88 FNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQEKHLLLNVFKGTPTDYPKDKTIH 147 Sbjct: 407 --- 463 Query: 148 ELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLASVLREKGVGAEAIVGIMADRSLEL 207 Sbjct: 464 523 Query: 208 IIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAMLLFQHHIVKDL-----TYAGGR- 261 Sbjct: 524 583 Query: 262 --------LELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMVEHRNLVNYI 313 Sbjct: 584 643 Query: 314 HWANKRY------VAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDG---EDKALL 364 Sbjct: 644 ------ 697 Query: 365 TRTIAEENKVNIVKLTPTHLRL-LEDMDLSRS--SIRTFIVGGEDLKIKVAEKIHRAFDG 421 Sbjct: 698 - 756 Query: 422 RIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVAGE 481 Sbjct: 757 --- 813 Query: 482 LCIGGDGVARGYLHKEALTAEKFV---------------DHP---------FNAGSKLYK 517 Sbjct: 814 873 Query: 518 TGDMARWLSDGTVEYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHN 577 Sbjct: 874 933 Query: 578 YLCAYVVSNKEVI-----ASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPA 632 Sbjct: 934 993 Query: 633 VDISEMLAASYEAPNNKVEEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALRE 692 Sbjct: 994 1053 Query: 693 -HGLRLEVKDLMQYPSIKELA 712 Sbjct: 1054 1074 >AGl2309_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 578 bits (1489), Expect = e-164, Method: Compositional matrix adjust. Identities = 0/1209 (0%), Positives = 0/1209 (0%), Gaps = 61/1209 (5%) Query: 1 LADFEHTHYQFEKVIQKLNLKSDASRNPLFDVMFV--LENLDYGLG-PNEEQAKVKLIEP 57 + ++ + Sbjct: 310 TTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTYPAP 369 Query: 58 MAEVAKFDLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGG 117 Sbjct: 370 --- 426 Query: 118 LDMLS-NQEKHLLLNVFKGTPTDY-PKDKTIHELFEEQADRTPDQLAVVCGGQALTYSEL 175 Sbjct: 427 -- 484 Query: 176 NEQANSLASVLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINY 235 Sbjct: 485 544 Query: 236 MLTDSQAAMLLFQHHIVKDLTYAGGRLELENSELYIRETGN--PVKASLPENLAYVIYTS 293 Sbjct: 545 -- 602 Query: 294 GTTGTPKGVMVEHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTI 353 Sbjct: 603 662 Query: 354 VIYDGEDKALLTRTIAEENKVNIVKLTPTHLRLLEDMDLSRSSIRTFIVGGEDLKIKVAE 413 Sbjct: 663 --- 719 Query: 414 KIHRAFDGRIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMEL 473 Sbjct: 720 ---- 775 Query: 474 LPVGVAGELCIGGDGVARGYLHKEALTAEKFVDHPFNAGSK---LYKTGDMARWLSDGTV 530 Sbjct: 776 835 Query: 531 EYLGRMDNQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVI 590 Sbjct: 836 895 Query: 591 ASEVKGRLSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKV 650 Sbjct: 896 955 Query: 651 EEILVDVWQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREHGLRLEVKDLMQYPSIKE 710 Sbjct: 956 1015 Query: 711 LAGYVKHEDV------QAPQEAVEGSVPFLPVQQWFFEQGLPQENHYNQAFMFYRKEGLD 764 Sbjct: 1016 ----- 1070 Query: 765 EEILRKAVVAILVHHDALRMVYKRTPDGITQWNRSADCAGAAFTLDVYDLRGQDEKRSIP 824 Sbjct: 1071 ------ 1124 Query: 825 ALSDELQKGLDLEEGLLVKLGLFKTSLGD---HLLVAVHHLVIDGVSWRILIADLETAY- 880 Sbjct: 1125 -- 1182 Query: 881 --RNIAAGAAASLPPKTASYRSWAQKLKEYASGKVLLKEAEYWKGITNTGSGPLPKDFGE 938 Sbjct: 1183 ----------- 1231 Query: 939 ENRGCGERMEVSLNFSKEQTAKLLRNCNTAYNTQINDVLLCSLGLAFKEWGGMDQLLVSL 998 Sbjct: 1232 1291 Query: 999 EGHGREEIFQGVSIDRTIGWFTTIFPVVLDMTRSHDLAYSLKRTKEMLRHVPHKGIGYGI 1058 Sbjct: 1292 1351 Query: 1059 WKYLADGNKELRAFEPEVSFNYLGEF-GREAGSSLLEFSRLSSGASISIDNNKLKGIDIN 1117 Sbjct: 1352 1411 Query: 1118 GLIMEGELELVFSYSTLEYTRETVAQLTAAYHTSLLQVIDHCAHRQTAEKTPWDYGDPDL 1177 Sbjct: 1412 1471 Query: 1178 SLEDLDTLL 1186 Sbjct: 1472 1480 Score = 382 bits (980), Expect = e-105, Method: Compositional matrix adjust. Identities = 0/1034 (0%), Positives = 0/1034 (0%), Gaps = 71/1034 (6%) Query: 1224 LNIEGYLNVEILNMVLNELTGKYEILRTAFFYHDIKKFKQAVLKERKLRIHYEDISSRSM 1283 Y + +N++ + K Sbjct: 33 HAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLA-KHGSREKLIIASKVSGP 91 Query: 1284 QEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKTDTGNFKVVYSFHHIIMDGWSAGIILQ 1343 + + L++ + + + + Sbjct: 92 -------SRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKL 144 Query: 1344 EVIAQYKARLQEAELKQEKAVP--YSDYLDWLDHQDKAAALDYWQSYLEAYESGTVIPE- 1400 + + + L A+ A + A + Sbjct: 145 GY-SWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVT 203 Query: 1401 -LQHQEKGFMHQQERTSLDAQATAKLKSLAEANGITLSSVIQTAWGVVLQKYSNTHDVVF 1459 + + +Q G + + Sbjct: 204 IQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFT 263 Query: 1460 GSVVSGRPSDIKGIERMVGLCINTVPVRVT--GGDQLSFIALAKKLNKDFIHANAFSFCQ 1517 + + + + + Sbjct: 264 RYSGEQTQK--AVAAYVDIARRHGLDPAQMALAFV---------RRQPFVASTLLGATTM 312 Query: 1518 LAEIQALSPMKNNLINHVVVYENYPVDQSLADLQEAEGREVKITAAQGFE---------Q 1568 + + L V+ Sbjct: 313 DQLKTNIESLHLELSEDVLAEIEAVHQVYTY-- 370 Query: 1569 TNYDLEILI-APGRTLQIKITYNGCKYSRDVINALMDNLMHVLSCAVSNPDQAAESIDMV 1627 Sbjct: 371 430 Query: 1628 SEQERNKLLYELNCTGTAYAKEKTIAQLF-EEQAERTPEAIALEFHGTVLSYRELNKRAN 1686 Sbjct: 431 - 489 Query: 1687 QLARVLRRNSVGANVIVPILVKRSLNLLVGILGILKAGGGYLPLDTDYPVDRIHYMLQDS 1746 Sbjct: 490 549 Query: 1747 QASLLL--TEKGLAAPLGLNEAVTILDIGSKQIQDEDDSNLQS-ITKADDLAYVLYTSGS 1803 Sbjct: 550 ----- 604 Query: 1804 TGNPKGVAVEQRGVHNFIKGITDRISFTEDKI--ILSVTTCSFDIFGLESLLPLTRGLKV 1861 Sbjct: 605 -- 662 Query: 1862 VIASEEEQKDPHLLNKVILDSEVNTIQLTPSRLKLMLNCSNTAESFKKLKLMMIGGEGFP 1921 Sbjct: 663 -------- 714 Query: 1922 KDLLVQLQKFTDSRI---YNMYGPTETTIWSTVKELTHENS-VNVGKPIANTQVYIVDQA 1977 Sbjct: 715 -- 772 Query: 1978 GHLAPIGVAGELCIAGDGVARGYLHKEELTASKFVDNPFMQGTK---MYTTGDLARWLPN 2034 Sbjct: 773 832 Query: 2035 GELDVIGRLDNQVKIGGYRIELGEIESVAARHDKITQCVVAGQPNSLGSQDLVLYFVAAE 2094 Sbjct: 833 892 Query: 2095 KISTSELVNFLSPVLPKYMMPQMYIQIDEIPLTANGKTNLKALPKPGNVRPELRDDYEEA 2154 Sbjct: 893 - 951 Query: 2155 VTDLQKEIQQVWSLILNIEQVGIYDNFFEVGGNSLKIVAMYNELQKLYPGKIQITDIFSY 2214 Sbjct: 952 - 1010 Query: 2215 PTISRLAQFIDNQS 2228 Sbjct: 1011 1024 >RSp0641_7 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 532 bits (1370), Expect = e-150, Method: Compositional matrix adjust. Identities = 0/1058 (0%), Positives = 0/1058 (0%), Gaps = 56/1058 (5%) Query: 1198 LSPMQEGMMYNTIVDAGSSTYFEQSELNIEGYLNVEILNMVLNELTGKYEILRTAFFYHD 1257 E E Y + +N++ + Sbjct: 7 PHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE 66 Query: 1258 IKKFKQAVLKERKLRIHYEDISSRSMQEQSSYIEQFKVQDRSNPFDLEQDCLLRVAVLKT 1317 + ++ S + Q E + Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNND--KGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 1318 DTGNFKVVYSFHHIIMDGWSAGIILQEVIAQYKA-RLQEAELKQEKAVPYSDYLDWLDHQ 1376 ++V + G A L Q + Sbjct: 125 YLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAF 184 Query: 1377 DKAAALD----YWQSYLEAYESGTVIP--ELQHQEKGFMHQQERTSLDAQATAKLKSLAE 1430 L + + ++ + + + L + Sbjct: 185 GVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGK 244 Query: 1431 ANGITLSSVIQTAWGVVLQKYSNTHDVVFGSVVSGRP-SDIKGIERMVGLCINTVPVRV- 1488 + + +YS + + + V + Sbjct: 245 YLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLD---PAQMALAFVRRQPF 301 Query: 1489 TGGDQLSFIALAKKLNKDFIHANA---FSFCQLAEIQALSPMKNNLINHVVVYE---NYP 1542 L A K I + Sbjct: 302 VASTLLG--ATTMDQLKTNIESLHLELSEDVLA--EIEAVHQVY-- 355 Query: 1543 VDQSLADLQEAEGREVKITAAQGFEQTNYDLEILIAPGRTLQIKITYNGCKYSRDVINAL 1602 Sbjct: 356 --------- 406 Query: 1603 MDN---------LMHVLSCAVSNPDQAAESIDMVSEQERNKLLYELNCTGTAYAKEKTIA 1653 Sbjct: 407 466 Query: 1654 QLFEEQAERTPEAIALEFHGTVLSYRELNKRANQLARVLRRNSVGANVIVPILVKRSLNL 1713 Sbjct: 467 526 Query: 1714 LVGILGILKAGGGYLPLDTDYPVDRIHYMLQDSQASLLLTEKGLAAPLGLNEAVTILDIG 1773 Sbjct: 527 - 585 Query: 1774 SKQIQDEDDSNLQSITKADDLAYVLYTSGSTGNPKGVAVEQRGVHNFIKGITDRISFTED 1833 Sbjct: 586 - 644 Query: 1834 KIILSVTTCSFDIFGLESLLPLTRGLKVVIASEEEQKDPHLLNKVILDSEVNTIQLTPSR 1893 Sbjct: 645 704 Query: 1894 LKLMLNCSNTAESFKKLKLMMIGGEGFPKDLLVQ-LQKFTDSRIYNMYGPTETTI----W 1948 Sbjct: 705 - 763 Query: 1949 STVKELTHENSVNVGKPIANTQVYIVDQAGHLAPIGVAGELCIAGDGVARGYLHKEELTA 2008 Sbjct: 764 - 822 Query: 2009 SKFVDNPFM-QGT-KMYTTGDLARWLPNGELDVIGRLDNQVKIGGYRIELGEIESVAARH 2066 Sbjct: 823 882 Query: 2067 DKITQCVVAGQPNSLGSQDLVLYFVAAEKISTSELVNFLSPVLPKYMMPQMYIQIDEIPL 2126 Sbjct: 883 942 Query: 2127 TANGKTNLKALPKPGNVRPELRDDYEEAVTDLQKEIQQVWSLILNIEQVGIYDNFFEVGG 2186 Sbjct: 943 - 1001 Query: 2187 NSLKIVAMYNELQKLYPGKIQITDIFSYPTISRLAQFI 2224 Sbjct: 1002 1039 Score = 495 bits (1274), Expect = e-139, Method: Compositional matrix adjust. Identities = 0/716 (0%), Positives = 0/716 (0%), Gaps = 12/716 (1%) Query: 6 HTHYQFEKVIQKLNLKSDASRNPLFDVMFVLENLD-YGLGPNEEQAKVKLIEPMAEVAKF 64 Sbjct: 324 383 Query: 65 DLTLTAKEAGGNLDFSLEYSSRLFNKATVQRMGEHYARLLAEAAANPDKELGGLDMLSNQ 124 Sbjct: 384 443 Query: 125 EKHLLLNVFKGTPTDYPKDKTIHELFEEQADRTPDQLAVVCGGQALTYSELNEQANSLAS 184 Sbjct: 444 503 Query: 185 VLREKGVGAEAIVGIMADRSLELIIAILGTLKAGGAYLPIDPEYPADRINYMLTDSQAAM 244 Sbjct: 504 563 Query: 245 LLFQHHIVKDLTYAGGRLELENSELYIRETGNPVKASLPENLAYVIYTSGTTGTPKGVMV 304 Sbjct: 564 623 Query: 305 EHRNLVNYIHWANKRYVAGEQTAFPLYSSISFDLTVTSIYTPLISGNTIVIYDGE---DK 361 Sbjct: 624 683 Query: 362 ALLTRTIAEENKVNIVKLTPTHLRL-LEDMDLSRS-SIRTFIVGGEDLKIKVAEKIHRAF 419 Sbjct: 684 - 742 Query: 420 DGRIEIYNEYGPTEATVGCMIYKYNAERDKGTSVSIGIPADNTQLYIVGSRMELLPVGVA 479 Sbjct: 743 -- 800 Query: 480 GELCIGGDGVARGYLHKEALTAEKFVDHPFNAGS--KLYKTGDMARWLSDGTVEYLGRMD 537 Sbjct: 801 860 Query: 538 NQVKIRGYRIETGEIENRLLQMPDITEAVVVARTDEQGHNYLCAYVVSNKEVIASEVKGR 597 Sbjct: 861 920 Query: 598 LSKELPNYMVPGFTVQIAKLPLSSNGKVDIKALPAVDISEMLAASYEAPNNKVEEILVDV 657 Sbjct: 921 980 Query: 658 WQRVLNIEPIGTNYNYYEMGGDSIKSILIVSALREH-GLRLEVKDLMQYPSIKELA 712 Sbjct: 981 1036 Score = 79.3 bits (194), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 15/199 (7%), Positives = 33/199 (16%), Gaps = 8/199 (4%) Query: 729 GSVPFLPVQQ--WFFEQGLPQENHYNQAFMFYRKEGLDEEILRKAVVAILVHHDALRMVY 786 + + ++A + + + + VA + Sbjct: 3 YHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 787 KRTPDGITQWNRSADCAGAAFTLDVYDLRGQ-DEKRSIPALSD-ELQKGLDLEEGLLVKL 844 T + W L + D L + E Sbjct: 63 GLTETYVGNWLAKHGSR---EKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLK 119 Query: 845 GLFKTSLGDH-LLVAVHHLVIDGVSWRILIADLETAYRNIAAGAAASLPPKTASYRSWAQ 903 L L + + G A A Sbjct: 120 RLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVS 179 Query: 904 KLKEYASGKVLLKEAEYWK 922 + + L ++ Sbjct: 180 NETAFGVMRYLHLADKHDL 198 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.135 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 179,595,986 Number of extensions: 8026111 Number of successful extensions: 29113 Number of sequences better than 1.0e-05: 305 Number of HSP's gapped: 27627 Number of HSP's successfully gapped: 630 Length of query: 2444 Length of database: 38,378,431 Length adjustment: 123 Effective length of query: 2321 Effective length of database: 24,192,349 Effective search space: 56150442029 Effective search space used: 56150442029 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)