BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0382.0026.p (2232 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ppsA_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 893 0.0 all2644_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 735 0.0 AGl2309_2 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 637 0.0 PA2400 [Q] COG1020 Non-ribosomal peptide synthetase modules and ... 621 e-177 all2644_1 [Q] COG1020 Non-ribosomal peptide synthetase modules a... 610 e-174 >BS_ppsA_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 792 Score = 893 bits (2307), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1500 (0%), Positives = 0/1500 (0%), Gaps = 54/1500 (3%) Query: 757 EHYEVSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSF 816 + ++ + + + ++ + + ++ L S Sbjct: 5 GSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVSVPNGFATTADAFNQFLDQSG 64 Query: 817 SF-VNKELVQAVDDHVHLAVEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKN 875 EL+ D + K A T + + + + + Sbjct: 65 VNQRIYELLDKTDIDDVTQLAKAGAQIRQW-IIDTPFQPELENAIREAYAQLSADDENAS 123 Query: 876 KHLLMLDVQHIIADGSSIPLLQKEIIHLYEHNPLPELNIQFKDFAKWQNDLFKTDYMNKQ 935 + + D S + + L + F + ++ Sbjct: 124 FAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAVKHVFASLFNDRAISYRVHQGYDH 183 Query: 936 KKYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMT 995 + L + +L S + G F Sbjct: 184 RGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQVVFITSAWGLGEMVVQGAVNPDEFYV 243 Query: 996 LLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEFLA 1055 + + +E + + + R+ S + LA Sbjct: 244 HKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHGKQVKIEDVPQEQRDIFSLTNEEVQELA 303 Query: 1056 GVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNPAFEVNGMHYAPY 1115 + Y H + + + Sbjct: 304 KQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQARPETVRSRGQVMERYTLHSQGKIIAEGR 363 Query: 1116 PYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLI 1175 ++ + + E ++ ++ Sbjct: 364 AIGHRIGAGPVKVIHDISEMNRIEPGDVLVTDMTDPDWEPIMKKASAIVTNRGGRTCHAA 423 Query: 1176 GDIDVL-DREELRDIRRYGQAGLPAAYNTKTIVEMFEAQAARIPDHLAVSGFDRSLTYRE 1234 L + + A + + S ++ Sbjct: 424 IIARELGIPAVVGCGDATERMKDGENVTVSCAEGDTGYVYAELLEFSVKSSSVETMPDLP 483 Query: 1235 LNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKR 1294 L N G+ R ++GV + R Sbjct: 484 LKVMMNVGNPDR-AFDFACLPNEGVGLARLEFIINRMIGVHPRALLEFDDQEPQLQNEIR 542 Query: 1295 FMLEDSGACMVLTDTAHRRSLQHGI--------REICLEEVAGNSGEQGNLEATASADSL 1346 M++ + L GI + + ++ + Sbjct: 543 EMMKGFDSPREFY----VGRLTEGIATLGAAFYPKRVIVRLSDFKSNEYANLVGGERYEP 598 Query: 1347 AYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNVALLAPFVFDASVKQIF 1406 G G + V R L K NV ++ PFV + Sbjct: 599 DEENPMLGFRGAGRYVSDSFRDCFALECEA-VKRVRNDMGLTNVEIMIPFVRTVDQAKAV 657 Query: 1407 SAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLAETSLCARIGVAH-- 1464 L L ++ ++ + + + + A Sbjct: 658 VEELARQGLKRGENGLKIIMMCEIPSNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSG 717 Query: 1465 -FIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPTECCVDATAF--TIKPEETGQIQEM 1521 + + A + K G EE + Sbjct: 718 VVSELFDERNDAVKALLSMAIRAAK--KQGKYVGICGQGPSDHEDFAAWLMEEGI--DSL 773 Query: 1522 PIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGM 1581 Sbjct: 774 833 Query: 1582 YMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQ 1641 Sbjct: 834 893 Query: 1642 RQEPYLCAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDP 1701 Sbjct: 894 - 952 Query: 1702 QEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARMEKY 1761 Sbjct: 953 -- 1010 Query: 1762 NLRLEVKHLFQYQTIGEVSKKVQDRAGHAGYGAVTGEAGLVPIQSWMVEHCRDTLQHRNL 1821 Sbjct: 1011 1070 Query: 1822 SFVLYREAGFGEDNIRKVFTEIIRHHDALRMVF-REQNRQMLQHNRGL---DGELFDFYL 1877 Sbjct: 1071 1130 Query: 1878 IDLA----DSPSFSEEXXXXXXXXXXSMDLEKGPLVKLALIRAGYGEHLLIVIHQMIIDH 1933 Sbjct: 1131 1190 Query: 1934 LSWRIILEDFNTAYTQLLNHEDIGLPPKTAPFLQWSNHLHEYADSIELLREQPYWDQVES 1993 Sbjct: 1191 1250 Query: 1994 IKAEPLPTDYK--ADEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTESIMLTALALT 2051 Sbjct: 1251 - 1309 Query: 2052 IRAWTGNAAVVVNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQL--PESRNIDLC--LE 2107 Sbjct: 1310 1369 Query: 2108 YVKEYLSGIPKQGGGYGVLKYLSS--HQEGIRFRLNPELSFNYMGQFDAEFNTSTFRISP 2165 Sbjct: 1370 ------- 1422 Query: 2166 LSGGEDRSGEEIWSYKLKFISFIRMNQLNIGIEYNQQQYARETVNALLQQYMEYLKKAAE 2225 Sbjct: 1423 - 1481 Score = 80.5 bits (197), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 0/403 (0%), Positives = 0/403 (0%), Gaps = 63/403 (15%) Query: 671 SVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHSNIERL 730 Sbjct: 970 - 1028 Query: 731 AAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPLFVMME 790 Sbjct: 1029 ----------- 1077 Query: 791 GPLDEGRLEHSFEALIQRHEVLRTSFSF-VNKELVQ---------------AVDDHVHLA 834 Sbjct: 1078 1137 Query: 835 VEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIP 894 Sbjct: 1138 --- 1194 Query: 895 LLQKEIIHLYEHN------PLPELNIQFKDFAKWQNDLFKTDYMNKQKKYW---LDVFSG 945 Sbjct: 1195 1254 Query: 946 ELP--ILNLPVDYPRDSG------QGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLL 997 Sbjct: 1255 ----------- 1303 Query: 998 AAFNVLLFKHTGQEDIIVGSPIAGRK----HKELEQMIGMFVN 1036 Sbjct: 1304 1346 >all2644_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 735 bits (1898), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1522 (0%), Positives = 0/1522 (0%), Gaps = 85/1522 (5%) Query: 761 VSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVN 820 SS + + + + A + + Sbjct: 7 PHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE 66 Query: 821 KELVQAVDD--HVHLAVEKYHADDETDLDQITSQFIR-----PFDLSKAPLIRAGLVEIR 873 + + + + + + + + L Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALH-DSLKRLQTDY 125 Query: 874 KNKHLLMLDVQHIIADGSSIPLLQKEIIHLYEHNPL-------PELNIQFKDFAKWQNDL 926 + + + + G + + L I++ + Sbjct: 126 LDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFG 185 Query: 927 FKTDYMNKQKKYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSS 986 K + + + P L + + Q E + A L Sbjct: 186 VMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKY 245 Query: 987 KEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSA 1046 F+ Q V + + + L+ S Sbjct: 246 LNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVAST 305 Query: 1047 HMVFKEFLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNPAFE 1106 Sbjct: 306 365 Query: 1107 VNGMHYAPYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQ 1166 Sbjct: 366 425 Query: 1167 VVALEHVLIGDIDVLDREELRDIRRYGQAGLPAAYNTKTIVEMFEAQAARIPDHLAVSGF 1226 Sbjct: 426 -- 483 Query: 1227 DRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEP 1286 Sbjct: 484 543 Query: 1287 AYPPERKRFMLEDSGACMVLTDTAHRRSL-QHGIREICLEEVAGNSGEQGNLEATASADS 1345 Sbjct: 544 -- 601 Query: 1346 LAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNVALLAPFVFDASVKQI 1405 Sbjct: 602 -- 659 Query: 1406 FSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLR-LLAETSLCARIGVAH 1464 Sbjct: 660 ----- 714 Query: 1465 FIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMP-I 1523 Sbjct: 715 --------- 765 Query: 1524 GAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIYHPGM-- 1581 Sbjct: 766 825 Query: 1582 ---YMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQ 1638 Sbjct: 826 885 Query: 1639 KDQRQEPYLCAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQL 1698 Sbjct: 886 945 Query: 1699 PDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARM 1758 Sbjct: 946 -- 1003 Query: 1759 EKYNLRLEVKHLFQYQTIGEVSKKVQ-DRAGHAGYGAVTGEAGLVPIQSWMVEHCRDTLQ 1817 Sbjct: 1004 1063 Query: 1818 HRNLSFVLYREAGFGEDNIRKVFTEIIRHHDALRMVFRE---------------QNRQ-- 1860 Sbjct: 1064 1123 Query: 1861 ----MLQHNRG-------LDGELFD-FYLIDLADSPSF-----SEEXXXXXXXXXXSMDL 1903 Sbjct: 1124 1183 Query: 1904 EKGPLVKLALIRAGYGEH--LLIVIHQMIIDHLSWRIILEDFNTAYTQLLNHEDIGLPPK 1961 Sbjct: 1184 1243 Query: 1962 TAPFLQWSNHLHEYADSIELLREQPYWDQVESIKAEPLPTDYKADEARVRDNLTLYQAFD 2021 Sbjct: 1244 1303 Query: 2022 CTETEQVMSSIRSNPHFTTESIMLTALALTIRAWTGNAAVVVNLGNHGRDMDSKDIDTYR 2081 Sbjct: 1304 1363 Query: 2082 TVGRFSILYPVALQLPESRNIDLCLEYVKEYLSGIPKQGGGYGVLKYLSSH--QEGIRFR 2139 Sbjct: 1364 1423 Query: 2140 LNPELSFNYMGQFDAEFN-TSTFRISPLSGGEDRSGEEIWSYKLKFISFIRMNQLNIGIE 2198 Sbjct: 1424 1483 Query: 2199 YNQQQYARETVNALLQQYMEYL 2220 Sbjct: 1484 1505 Score = 62.4 bits (150), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 0/567 (0%), Positives = 0/567 (0%), Gaps = 82/567 (14%) Query: 675 VWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHSNIERLAAYI 734 Sbjct: 970 - 1028 Query: 735 EGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLD 794 Sbjct: 1029 ---------- 1078 Query: 795 EGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHL--------------------- 833 Sbjct: 1079 1138 Query: 834 ------------------AVEKYHADDETD-LDQITSQFIRPFDLSKAPLIRAGLVEIRK 874 Sbjct: 1139 1198 Query: 875 NK-HLLMLDVQHIIADGSSIPLLQKEIIHLY------EHNPLPELNIQFKDFA-KWQNDL 926 Sbjct: 1199 1258 Query: 927 FKTDYMNKQKKYWLDVFSGELPILNLPVDY-PRDSGQGDQGERLTCNAGRELTQRLNEYS 985 Sbjct: 1259 --- 1315 Query: 986 SKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRK----HKELEQMIGMFVNTLA-- 1039 Sbjct: 1316 1375 Query: 1040 LRNRPSAHMVFKEFLAGVKENALQAYEHQ-DYPFEELVDHLNMDRNLSGTALFNVMFVLQ 1098 Sbjct: 1376 -- 1433 Query: 1099 VMDNPAFEVNGMHYAPYPY---HNKTAKFD----LALQVFPGLDELKFEFTYAAKLFKRS 1151 Sbjct: 1434 - 1492 Query: 1152 TIESFARRFLRVLEQVVALEHVLIGDI 1178 Sbjct: 1493 -- 1517 >AGl2309_2 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 637 bits (1642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/1480 (0%), Positives = 0/1480 (0%), Gaps = 58/1480 (3%) Query: 761 VSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVN 820 SS + + + + A + + Sbjct: 7 PHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTE 66 Query: 821 -KELVQAVDDHVHLAVEKYHADDETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLL 879 + + L + + A +++ + Sbjct: 67 TYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIR-PDQALDRKNIREALHDSLKRLQTDY 125 Query: 880 MLDVQHIIADGSSIPLLQKEIIHLY------EHNPLPELNIQFKDFAKWQNDLFKTDYMN 933 + Q + + + L L + + Sbjct: 126 LDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFG 185 Query: 934 KQKKYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLF 993 + + L V ++ + + S Sbjct: 186 ----VMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTL 241 Query: 994 MTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEF 1053 + + + L A + + F Sbjct: 242 TGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPF 301 Query: 1054 LAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQV-MDNPAFEVNGMHY 1112 Sbjct: 302 361 Query: 1113 APYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEH 1172 Sbjct: 362 421 Query: 1173 VLIGDIDVLDREELRDIRRYGQAGLPAAYNTKTIVEMFEAQAARIPDHLAVSGFDRSLTY 1232 Sbjct: 422 481 Query: 1233 RELNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPER 1292 Sbjct: 482 541 Query: 1293 KRFMLEDSGACMVLTDTAHRRS-LQHGIREICLEEVAGNSGEQGNLEATASADSLAYVIY 1351 Sbjct: 542 - 600 Query: 1352 TSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGPNLNVALLAPFV-FDASVKQIFSAFL 1410 Sbjct: 601 --- 657 Query: 1411 LGHHLNIVPGDVRQDVIQLAEYYKQNKIDISDGTPAYLRLLAETSLCARIGVAHFIIGGE 1470 Sbjct: 658 ------ 711 Query: 1471 ALSIAEVKRFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIKNC 1530 Sbjct: 712 ------- 764 Query: 1531 SVYILDEQKRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIY---HPGMYMYKTG 1587 Sbjct: 765 824 Query: 1588 DMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYL 1647 Sbjct: 825 884 Query: 1648 CAYVVCRDEQVLPGLRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDH 1707 Sbjct: 885 944 Query: 1708 SLGYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARMEKYNLRLEV 1767 Sbjct: 945 1004 Query: 1768 KHLFQYQTIGEVSKKVQ-DRAGHAGYGAVTGEAGLVPIQSWMVEHCRDTLQHRNLSFVLY 1826 Sbjct: 1005 1064 Query: 1827 REAGFGEDNIRKVFTEIIRHHDALRMVFREQNRQMLQHNRGLDG--ELFDFYLIDLADSP 1884 Sbjct: 1065 1124 Query: 1885 SFSEEXXXXXXXXXXSMDLEKGPLVK--LALIRAGYGEHLLIVIHQMIIDHLSWRIILED 1942 Sbjct: 1125 -------- 1176 Query: 1943 FNTAYTQLLNHEDIGLPPKTAPFLQWSNHLHEYADSIELLREQPYWDQVESIKAEPLPTD 2002 Sbjct: 1177 -------- 1228 Query: 2003 YKADEARVRDNLTLYQAFDCTETEQVMSSIRSNPHFTTESIMLTALALTIRAWTGNAAVV 2062 Sbjct: 1229 1288 Query: 2063 VNLGNHGRDMDSKDIDTYRTVGRFSILYPVALQLPESRNIDLCLEYVKEYLSGIPKQGGG 2122 Sbjct: 1289 1348 Query: 2123 YGVLKYLSSHQEGIRFRLNPELSFNYMGQFDAEFNT-STFRISPLSGGEDRSGEEIWSYK 2181 Sbjct: 1349 - 1407 Query: 2182 LKFISFIRMNQLNIGIEYNQQQYARETVNALLQQYMEYLK 2221 Sbjct: 1408 1447 Score = 83.6 bits (205), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 0/543 (0%), Positives = 0/543 (0%), Gaps = 77/543 (14%) Query: 669 EISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHSNIE 728 Sbjct: 956 - 1014 Query: 729 RLAAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPLFVM 788 Sbjct: 1015 ---------- 1064 Query: 789 MEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHL-AVEKYHADDETDLD 847 Sbjct: 1065 1124 Query: 848 QITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIHLYEHN 907 Sbjct: 1125 ---- 1180 Query: 908 PLPELNIQFKDFA--KWQNDLFKTDYMNKQKKYWLDVFSGELPILNLPVDYPRDSGQGDQ 965 Sbjct: 1181 ---- 1236 Query: 966 GERLT------CNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPI 1019 Sbjct: 1237 --- 1293 Query: 1020 AGR----KHKELEQMIGMFVNTL---------------------ALRNRPSAHMVFKEFL 1054 Sbjct: 1294 ---- 1349 Query: 1055 AGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNPAFEVNG-MHYA 1113 Sbjct: 1350 --------- 1400 Query: 1114 PYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHV 1173 Sbjct: 1401 ------- 1453 Query: 1174 LIG 1176 Sbjct: 1454 1456 >PA2400 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 621 bits (1601), Expect = e-177, Method: Compositional matrix adjust. Identities = 0/1161 (0%), Positives = 0/1161 (0%), Gaps = 70/1161 (6%) Query: 666 SKAEISVGQVWGAVLGMNPMSVTADFYEIGGDSIIAIEIVNTLNTIMGLSLQVPVLFEHS 725 + A + + + + + + + + + Sbjct: 152 APAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLL 211 Query: 726 NIERLAAYIEGQAGTDKDTRGNSAIPRIAAAEHYEVSSSQKRIYILNQLNARSTSYNIPL 785 N + + + A ++ S Sbjct: 212 NRS---FEVGLAEVSQYEGVELLAYSC---LGFGTLTGKYLNGAKPAGARNTLFSRFTRY 265 Query: 786 FVMMEGPLDEGRLEHSFEALIQRHEVLRTSFSFVNKELVQAVDDHVHLAVEKYH---ADD 842 ++ + + ++ + ++ + Sbjct: 266 SGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLE 325 Query: 843 ETDLDQITSQFIRPFDLSKAPLIRAGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIH 902 Sbjct: 326 385 Query: 903 LY------EHNPLPELNIQFKDFAKWQNDLFKTDYMNKQKKYWLDVFSGELPILNLPVDY 956 Sbjct: 386 445 Query: 957 PRDSGQGDQGERLTCNAGRELTQRLNEYSSKEKTTLFMTLLAAFNVLLFKHTGQEDIIVG 1016 Sbjct: 446 505 Query: 1017 SPIAGRKHKELEQMIGMFVNTLALRNRPSAHMVFKEFLAGVKENALQAYEHQDYPFEELV 1076 Sbjct: 506 565 Query: 1077 DHLNMDRNLSGTALFNVMFVLQVM--DNPAFEVNGMHYAPYPYHNKTAKFDLALQVFPGL 1134 Sbjct: 566 625 Query: 1135 DELKFEFTYAAKLFKRSTIESFARRFLRVLEQVVALEHVLIGDIDVLDREELRDIRRYGQ 1194 Sbjct: 626 685 Query: 1195 AGLPAAYNTKTIVEMFEAQAARI-PDHLAVSGFDRSLTYRELNEQANQLARVLIRNGACK 1253 Sbjct: 686 - 744 Query: 1254 DRVVGIIAERSTNFAVGIMGVLKSGAAYLPIEPAYPPERKRFMLEDSGA--CMVLTDTAH 1311 Sbjct: 745 804 Query: 1312 RRSLQHGIREICL-----EEVAGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEH 1366 Sbjct: 805 ---- 860 Query: 1367 RSVTNLAEALDEKIYSLHGPNLNVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDV 1426 Sbjct: 861 ------- 913 Query: 1427 IQLAE--YYKQNKIDISDGT--PAYLRLLAETSLCARIG----VAHFIIGGEALSIAEVK 1478 Sbjct: 914 -- 971 Query: 1479 RFYTSFANHKPPYITNVYGPTECCVDATAFTIKPEETGQIQEMPIGAPIKNCSVYILDEQ 1538 Sbjct: 972 --- 1028 Query: 1539 KRMVPRGVLGELYIGGHGVARGYCNNKALTSSRFVEDIY-HPGMYMYKTGDMGKWTEDGL 1597 Sbjct: 1029 1088 Query: 1598 IHFAGRADHQVKIRGFRIELDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYVVCRDEQ 1657 Sbjct: 1089 - 1147 Query: 1658 VLPG----------LRGYLGEYLPDYMIPRVIMPVDQIPMTANGKADTSQLPDPQEMRDH 1707 Sbjct: 1148 ---- 1203 Query: 1708 SL---GYGAPRNRTEEILCTVWSEVLELRRIGIHDNFFAAGGDSIKAIQAAARM-EKYNL 1763 Sbjct: 1204 1263 Query: 1764 RLEVKHLFQYQTIGEVSKKVQ 1784 Sbjct: 1264 1284 Score = 166 bits (419), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 0/442 (0%), Positives = 0/442 (0%), Gaps = 34/442 (7%) Query: 1567 LTSSRFVEDIY-HPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIELDEIRHRLL 1625 + R + + + +E A Q E+ + R Sbjct: 1 MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPE 60 Query: 1626 SCDGVQAAVVLVQKDQRQEPYLCAYVVC---RDEQVLPGL----RGYLGEYLPDYMIPRV 1678 + + V + + R + Sbjct: 61 TQGLTETYVGNWLAKH-----GSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALH 115 Query: 1679 IMPVDQIPMTANGKADTSQLPDPQE---MRDHSLGYGAPRNRTEEILCTVWSEVLELRRI 1735 + + +L T+ + R Sbjct: 116 DSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSW----TDSAPAVSLLDTLDALAEYQRAG 171 Query: 1736 GIHDNFFAAGGDSIKAIQAAARMEK-YNLRLEVKHLFQYQTI-GEVSKKVQDRAGHAGYG 1793 I + + + +++ + EV + Sbjct: 172 KIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGVELL 231 Query: 1794 AVTGEAGLVPI-----QSWMVEHCRDTLQHRNLSFVLYREAGFGEDNIRKVFTEIIRHHD 1848 A + + R+TL R + + + + Sbjct: 232 AYSCLGFG-TLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDPAQ 290 Query: 1849 ALRMVFREQNRQMLQHNRGLDGEL-FDFYLIDLADSPSFSEEXXXXXXXXXXSMDLEKGP 1907 R Q + L S + P Sbjct: 291 MALAFVRRQPFVASTLLGA-TTMDQLKTNIESLHLELSED---VLAEIEAVHQVYTYPAP 346 Query: 1908 LVKLALIRAGYGEHLLIVI-HQMIIDHLSWRIILEDFNTAYTQLLNHEDIGLPPKTAPFL 1966 Sbjct: 347 406 Query: 1967 QWSNHLHEYADSIELLREQPYW 1988 Sbjct: 407 428 >all2644_1 [Q] COG1020 Non-ribosomal peptide synthetase modules and related proteins Length = 346 Score = 610 bits (1574), Expect = e-174, Method: Compositional matrix adjust. Identities = 0/1070 (0%), Positives = 0/1070 (0%), Gaps = 66/1070 (6%) Query: 754 AAAEHYEVSSSQKRIYILNQLNARSTSYNIPLFVMMEGPLDEGRLEHSFEALIQRHEVLR 813 + S + + + ++ + + L ++ R Sbjct: 20 TMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSR 79 Query: 814 TSFSFVNKELVQ--AVDDHVHLAV----EKYHADDETDLDQITSQFI-RPFDLSKAPLIR 866 +K D + + L ++ + ++ Sbjct: 80 EKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTN 139 Query: 867 AGLVEIRKNKHLLMLDVQHIIADGSSIPLLQKEIIHLYEHNPLPELNIQFKDFAKWQNDL 926 D + +I ++ N +++ A + Sbjct: 140 CFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLP 199 Query: 927 FKTDYMNKQKKYWLDVFSGELPILNLPVDYPRDSGQGDQGERLTCNAGRELTQRLNEYSS 986 N G + G Sbjct: 200 RIVTIQNPYSLLNRSFEVGLAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLF 259 Query: 987 KEKTTLFMTLLAAFNVLLFKHTGQEDIIVGSPIAGRKHKELEQMIGMFVNTLALRNRPSA 1046 T + + ++ + T + + + Sbjct: 260 SRFTRYSGEQTQKAVAAYVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNI 319 Query: 1047 HMVFKEFLAGVKENALQAYEHQDYPFEELVDHLNMDRNLSGTALFNVMFVLQVMDNPAFE 1106 Sbjct: 320 379 Query: 1107 VNGMHYAPYPYHNKTAKFDLALQVFPGLDELKFEFTYAAKLFKRSTIESFARRFLRVLEQ 1166 Sbjct: 380 439 Query: 1167 VVALEHVLIGDIDVLDREELRDIRRYGQ--AGLPAAYNTKTIVEMFEAQAARIPDHLAVS 1224 Sbjct: 440 ---- 495 Query: 1225 GFDRSLTYRELNEQANQLARVLIRNGACKDRVVGIIAERSTNFAVGIMGVLKSGAAYLPI 1284 Sbjct: 496 555 Query: 1285 EPAYPPERKRFMLEDSGACMVLTDTAHRRSL------------------QHGIREICLEE 1326 Sbjct: 556 615 Query: 1327 VAGNSGEQGNLEATASADSLAYVIYTSGSTGKPKGVMIEHRSVTNLAEALDEKIYSLHGP 1386 Sbjct: 616 --------- 666 Query: 1387 NL----NVALLAPFVFDASVKQIFSAFLLGHHLNIVPGDVRQDVIQLAEYYKQNKIDISD 1442 Sbjct: 667 726 Query: 1443 GTPAYLRLLAETSLCARIGVAHFIIGGEALSIAEVKRFYTSFANHKPPYITNVYGPTECC 1502 Sbjct: 727 ------ 780 Query: 1503 VDATAFTIKPEETGQIQEMPIGAPIKNCSVYILDEQKRMVPRGVLGELYIGGHGVARGYC 1562 Sbjct: 781 ----- 835 Query: 1563 NNKALTSSRF------VEDIYHPGMYMYKTGDMGKWTEDGLIHFAGRADHQVKIRGFRIE 1616 Sbjct: 836 895 Query: 1617 LDEIRHRLLSCDGVQAAVVLVQKDQRQEPYLCAYVVCRDEQVLPG-LRGYLGEYLPDYMI 1675 Sbjct: 896 955 Query: 1676 PRVIMPVDQIPMTANGKADTSQLPDPQEMRDHSLGYGAPRNRTEEILCTVWSEVLELRRI 1735 Sbjct: 956 --- 1012 Query: 1736 GIHDNFFAAGGDSIKAIQAAARMEK-YNLRLEVKHLFQYQTIGEVSKKVQ 1784 Sbjct: 1013 1062 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 167,124,260 Number of extensions: 7193193 Number of successful extensions: 15412 Number of sequences better than 1.0e-05: 319 Number of HSP's gapped: 14433 Number of HSP's successfully gapped: 366 Length of query: 2232 Length of database: 38,378,431 Length adjustment: 122 Effective length of query: 2110 Effective length of database: 24,307,683 Effective search space: 51289211130 Effective search space used: 51289211130 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 124 (52.4 bits)