BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0382.0025.p
         (353 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

MT0593 [QR] COG0500 SAM-dependent methyltransferases                   94   4e-19
Rv0567 [QR] COG0500 SAM-dependent methyltransferases                   94   4e-19
Z4850 [QR] COG0500 SAM-dependent methyltransferases                    56   8e-08

>MT0593 [QR] COG0500 SAM-dependent methyltransferases
          Length = 340

 Score = 93.6 bits (231), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 74/277 (26%), Positives = 126/277 (45%), Gaps = 15/277 (5%)

Query: 25  VMQIVSGLGFSLAVKTAVELGVFSAFNNGKITVSAMAESLSL-NAPALSRLLKALQSISL 83
           +M I  G G S  + TAV LG+F+   +  +T  A+A+ L L   PA+   L AL S+ L
Sbjct: 9   IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAID-FLDALVSLDL 67

Query: 84  VTQDEEG---NYEVTEYGATLLTGKSPRSLEPLVKYLLHETVVQSMVEMKYSIQTGKPAF 140
           + +D +G   +Y  T   A  L    P     L+K + +E   +   ++  +++TGK   
Sbjct: 68  LARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLK-IWNERNYRFWADLTEALKTGKAQS 126

Query: 141 E-----KVFGEQWYGNHEMKDNYLQTMDKAMEIYSRMSLPALLASYPFGQYDVIVDVAGG 195
           E     + F E  Y +    + ++  MD A    SR ++  L   +PF +Y  + DV   
Sbjct: 127 EVKQTGRPFFEALYADPRRLEAFMAAMDAA----SRRNIELLAKRFPFERYRRLCDVGCA 182

Query: 196 LGQLISGVLQSVPEAKGILFDLPETIERASANIGGSEIGERCTLVPGSMFEQIPSGGSLY 255
            G L   V  + P  + + FDLP   E A   +    +GER     G           + 
Sbjct: 183 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 242

Query: 256 MISKVLNDWDDEHVVSILANIRKVMTREAKLIIIENL 292
            + ++L+DW+ +    ++A   + +++E   I+IE L
Sbjct: 243 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETL 279


>Rv0567 [QR] COG0500 SAM-dependent methyltransferases
          Length = 339

 Score = 93.6 bits (231), Expect = 4e-19,   Method: Compositional matrix adjust.
 Identities = 74/277 (26%), Positives = 126/277 (45%), Gaps = 15/277 (5%)

Query: 25  VMQIVSGLGFSLAVKTAVELGVFSAFNNGKITVSAMAESLSL-NAPALSRLLKALQSISL 83
           +M I  G G S  + TAV LG+F+   +  +T  A+A+ L L   PA+   L AL S+ L
Sbjct: 8   IMAIGGGYGPSKVLLTAVGLGLFTELGDEAMTAEAIADRLGLLKRPAID-FLDALVSLDL 66

Query: 84  VTQDEEG---NYEVTEYGATLLTGKSPRSLEPLVKYLLHETVVQSMVEMKYSIQTGKPAF 140
           + +D +G   +Y  T   A  L    P     L+K + +E   +   ++  +++TGK   
Sbjct: 67  LARDGDGPGSHYRNTPETAHFLDEARPTYAGGLLK-IWNERNYRFWADLTEALKTGKAQS 125

Query: 141 E-----KVFGEQWYGNHEMKDNYLQTMDKAMEIYSRMSLPALLASYPFGQYDVIVDVAGG 195
           E     + F E  Y +    + ++  MD A    SR ++  L   +PF +Y  + DV   
Sbjct: 126 EVKQTGRPFFEALYADPRRLEAFMAAMDAA----SRRNIELLAKRFPFERYRRLCDVGCA 181

Query: 196 LGQLISGVLQSVPEAKGILFDLPETIERASANIGGSEIGERCTLVPGSMFEQIPSGGSLY 255
            G L   V  + P  + + FDLP   E A   +    +GER     G           + 
Sbjct: 182 DGLLSRIVAAAHPHLQCVSFDLPAVTEIARRKLTAEGLGERVQACAGDFLADPLPAADVI 241

Query: 256 MISKVLNDWDDEHVVSILANIRKVMTREAKLIIIENL 292
            + ++L+DW+ +    ++A   + +++E   I+IE L
Sbjct: 242 TMGQILHDWNLDRKQQLVAKAYEALSKEGAFIVIETL 278


>Z4850 [QR] COG0500 SAM-dependent methyltransferases
          Length = 352

 Score = 56.2 bits (134), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 62/245 (25%), Positives = 103/245 (42%), Gaps = 20/245 (8%)

Query: 56  TVSAMAESLSLNAPALSRLLKALQSISLVTQDEEGNYEVTEYGATLLTGKSPRSLEPLVK 115
           T++ + E   +N  A S LL    S  ++T  +EG Y + + G  LL     R      +
Sbjct: 50  TLADITEHSHINEYATSVLLDMGLSGRIITC-KEGIYYLAKIGHYLLHDTMTRVNMDFTQ 108

Query: 116 YLLHETVVQSMVEMKYSIQTGKPAFEKVFGEQWYGNH----EMKDNYLQTMDKAMEIYS- 170
               +   Q +  +  S+  GKP+  KVFG+ W   +    ++ D   ++       YS 
Sbjct: 109 ----DVCYQGLFFLADSLNEGKPSGLKVFGD-WSTIYPALSQLPDAARESWFAFDHYYSD 163

Query: 171 ---RMSLPALLASYPFGQYDVIVDVAGGLGQLISGVLQSVPEAKGILFDLPETIERASAN 227
                +LP + A+ P      + DV G  G+      +        L DLP+ I  A  N
Sbjct: 164 GAFNAALPYVFANNP----TTLYDVGGNTGKWALRCCKYNENIAVTLLDLPQQIVLAKEN 219

Query: 228 IGGSEIGERCTLVPGSMFEQIPSGG--SLYMISKVLNDWDDEHVVSILANIRKVMTREAK 285
           I  +   +R       M    P  G   ++ +S+ L+ +  E ++SIL+ I  VM   AK
Sbjct: 220 IANAGFSDRIDFHAVDMLSDAPLPGEADIWWMSQFLDCFSPEQIISILSKIASVMKPGAK 279

Query: 286 LIIIE 290
           + I+E
Sbjct: 280 VCIME 284


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.316    0.133    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 24,136,174
Number of extensions: 944261
Number of successful extensions: 5352
Number of sequences better than 1.0e-05: 3
Number of HSP's gapped: 5351
Number of HSP's successfully gapped: 3
Length of query: 353
Length of database: 38,378,431
Length adjustment: 107
Effective length of query: 246
Effective length of database: 26,037,693
Effective search space: 6405272478
Effective search space used: 6405272478
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 116 (49.3 bits)