BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0377.0032.p (240 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SPy1202 [K] COG2188 Transcriptional regulators 82 5e-16 AGc4722 [K] COG2188 Transcriptional regulators 79 5e-15 PA2299 [K] COG2188 Transcriptional regulators 79 8e-15 BH0419 [K] COG2188 Transcriptional regulators 76 4e-14 RSc1997 [K] COG2188 Transcriptional regulators 75 7e-14 >SPy1202 [K] COG2188 Transcriptional regulators Length = 241 Score = 82.4 bits (202), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 65/223 (29%), Positives = 111/223 (49%), Gaps = 9/223 (4%) Query: 9 PLYQQIQKILKDRILHGIYPLGSIIPSEPLLEKEFGVSKMTVRGAVQELAQEGYVQKRSG 68 P Y +I +K I GI+P+GS +PSE L + F VS+MT+R A+ L +EG +++R G Sbjct: 12 PAYIKIHDAIKKDIDLGIWPIGSRLPSERHLAEHFTVSRMTLRQAITLLVEEGILERRIG 71 Query: 69 IGTIVTRNTSYQKLSKGKRFTELLVEEGHRLEKRLLS-SKLIANAAGTEEFN-RYGPYCQ 126 GT V + +K+ FTE++ +G + +LLS K +A+ +E N Sbjct: 72 SGTYVASHRVQEKMRGTTSFTEIIRSQGRQPSSKLLSYQKQLASDTEVKELNLDKTDLVI 131 Query: 127 RIERLYILNGQPYIHLMHFLTAAALPDGGAKEMS-TDI-QSLYDSLEENNIVLENFKDRF 184 R+ER+ + P ++ + A++P+ K + DI + + SL N + K Sbjct: 132 RMERIRYADSVPLVYEI-----ASIPEKFIKTVKRADITEHFFHSLIANGYEIGKSKQTI 186 Query: 185 FVEPAAAEVCLLLELPPGTHVLKRLRNSYDGEGRLIEHSIGSY 227 + + A+ V LE+ G +L + SY +G+ E+ Y Sbjct: 187 YAKLASERVASYLEVAKGHAILALTQVSYFTDGKPFEYVRSQY 229 >AGc4722 [K] COG2188 Transcriptional regulators Length = 158 Score = 79.3 bits (194), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 0/232 (0%), Positives = 0/232 (0%), Gaps = 11/232 (4%) Query: 3 LKRKQGPLYQQIQKILKDRILHGIYPLGSIIPSEPLLEKEFGVSKMTVRGAVQELAQEGY 62 L + + G+ +I + L+ K V + Sbjct: 11 LTKAGIAFATVTYDYDPNADRIGLQAAEAIGEAPHLVLKTLMAELDGKPVCVVVPSDREV 70 Query: 63 VQKRSGIGTIVTRNTS--YQKLSKGKRFTELLVEEGHRLEKRLLSSKLIANAAGTEEFN- 119 K+ + + + + ++ + + + Sbjct: 71 SMKKLAAAFGGKSANMMKPADAERATGYHVGGISPFGQKKQVPTAIEAD-AMVHDYVYMN 129 Query: 120 --RYGPYCQRIERLYILNGQPYIHLMHFLTAAALPDGGAKEMSTDIQSLYDSLEENNIVL 177 Sbjct: 130 GG----- 184 Query: 178 ENFKDRFFVEPAAAEVCLLLELPPGTHVLKRLRNSYDGEGRLIEHSIGSYNT 229 Sbjct: 185 236 >PA2299 [K] COG2188 Transcriptional regulators Length = 249 Score = 78.6 bits (192), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 48/133 (36%), Positives = 77/133 (57%), Gaps = 4/133 (3%) Query: 9 PLYQQIQKILKDRILHGIYPLGSIIPSEPLLEKEFGVSKMTVRGAVQELAQEGYVQKRSG 68 PLY Q++++L+ RIL G+YP S +PSE L K F VS++TVR A+ +L +EG + K G Sbjct: 11 PLYSQLKELLRGRILDGVYPPLSRMPSENELGKAFDVSRITVRQALGDLQKEGLIFKIHG 70 Query: 69 IGTIVTRNTSYQKLSKGKRFTELLVEEGHRLEKRLLSSKLIANAAGTEEFNRY---GPYC 125 GT V R ++Q +S + E + + G+ + RL + + A E R P C Sbjct: 71 KGTFVARPKAFQNVSTLQGLGESMTQMGYEVINRLHGLRYVPAGARVAERLRVEEGSPVC 130 Query: 126 QRIERLYILNGQP 138 + I+R+ ++N +P Sbjct: 131 E-IKRVRLVNREP 142 >BH0419 [K] COG2188 Transcriptional regulators Length = 240 Score = 76.3 bits (186), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 67/232 (28%), Positives = 113/232 (48%), Gaps = 6/232 (2%) Query: 9 PLYQQIQKILKDRILHGIYPLGSIIPSEPLLEKEFGVSKMTVRGAVQELAQEGYVQKRSG 68 P+Y QI++ +K +I G+ G ++ SE + + VS+MTVR A+ L +GY+ K+ G Sbjct: 9 PIYYQIEEQIKQQIESGVLKPGDMLKSEREYAEYYDVSRMTVRQAINNLVNQGYIYKKKG 68 Query: 69 IGTIVTRNTSYQKLSKGKRFTELLVEEGHRLEKRLLSSKLI-ANAAGTEEFN-RYGPYCQ 126 GT V Q L+ FTE + + G RLL +LI A A +E N + Sbjct: 69 SGTYVQEKKIEQALNGLTSFTEDMRKRGMEPSSRLLKFELIPATAKIAKELNLKENTPVT 128 Query: 127 RIERLYILNGQPYIHLMHFLTAAALPDGGAKEMSTDIQSLYDSLEEN-NIVLENFKDRFF 185 I+R+ +G P I + L A L G +E+ QSLY +EE N+ + + Sbjct: 129 EIKRIRYGDGVP-IAIERNLLPANLVKGLNEEIIN--QSLYQYIEEELNLRIADALQVIE 185 Query: 186 VEPAAAEVCLLLELPPGTHVLKRLRNSYDGEGRLIEHSIGSYNTALHHYLVS 237 A+ LLE+ G+ +L R ++ +G ++E +Y + ++++ Sbjct: 186 ASTASKTEADLLEIQKGSPILLIERKTFLADGTVLELVKSAYRADRYKFMIT 237 >RSc1997 [K] COG2188 Transcriptional regulators Length = 274 Score = 75.5 bits (184), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 70/234 (29%), Positives = 110/234 (47%), Gaps = 14/234 (5%) Query: 9 PLYQQIQKILKDRILHGIYPLGSIIPSEPLLEKEFGVSKMTVRGAVQELAQEGYVQKRSG 68 PLYQQI+ ++ + G + G +IPSE L + VS+ TVR A+ ELA E V +R G Sbjct: 42 PLYQQIKTLILQSLQAGEWKPGEMIPSEMELAARYKVSQGTVRKAIDELAAENLVARRQG 101 Query: 69 IGTIVTRNTSYQKLSKGKRFTELLVEEG--HRLEKRLLSSKLIANAAGTEEFNRY----- 121 GT VT T Y++ + RF L+ E+G H R+L K + A E R Sbjct: 102 KGTFVT--THYEEGVQ-FRFLRLMPEQGEQHYPSSRVLECKRLRAPA---EIARLLDLKP 155 Query: 122 GPYCQRIERLYILNGQPYIHLMHFLTAAALPDGGAKEMSTDIQSLYDSLE-ENNIVLENF 180 G +I R+ +G+P + +L ++ A++++ +Y E E + + Sbjct: 156 GDSVVQIRRVLFFSGEPTVFEEIWLPGSSFKGLTAEKLTDWKGPMYAFFEAEFGVRMLRA 215 Query: 181 KDRFFVEPAAAEVCLLLELPPGTHVLKRLRNSYDGEGRLIEHSIGSYNTALHHY 234 +R A A LL + PG+ +L R S+ + +E G Y T H+Y Sbjct: 216 TERIRAVAADAGTAGLLSVAPGSPLLSVERVSHTFGDKPVELRRGLYVTTRHYY 269 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.137 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,650,898 Number of extensions: 721347 Number of successful extensions: 1619 Number of sequences better than 1.0e-05: 111 Number of HSP's gapped: 1616 Number of HSP's successfully gapped: 111 Length of query: 240 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 137 Effective length of database: 26,499,029 Effective search space: 3630366973 Effective search space used: 3630366973 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)