BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0377.0027.p (778 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins 115 3e-25 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 80 1e-14 BH3679 [T] COG4753 Response regulator containing CheY-like recei... 77 1e-13 BH0793 [T] COG4753 Response regulator containing CheY-like recei... 69 3e-11 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 69 4e-11 >BH0483 [K] COG2207 AraC-type DNA-binding domain-containing proteins Length = 769 Score = 115 bits (288), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 124/527 (23%), Positives = 230/527 (43%), Gaps = 45/527 (8%) Query: 265 GIHNLVLDGEQYSVVSVQSDENGWTYVTTMPSYQFFSRVAHVQTLILIVFCITVVTGIAA 324 G +L L Y+V SD N WTYV+ + S + + + + + ++ + Sbjct: 258 GQFSLPLSHSTYTVTFRTSDYNQWTYVSVISSRELAKQSNAIGAFTMYISAGVLLLSLLY 317 Query: 325 ALLLAKRQYHPIKDLMEFARLGSSGNDALKT-RNEWEWIRQTLH---DYSARID------ 374 + + ++R Y P+++L + S A K ++E+E I +H D + ++ Sbjct: 318 SWVGSRRIYRPVQELYQMITATFSAGSAKKPPKDEFELIHAHIHNVLDLNNELEEKLQGQ 377 Query: 375 ---LQEPFVRNQCMLLLLKHGKPDDPEIEQMILSAGFRHPQEQGLYFSAILSWDDAAPGG 431 L++ FV N L+ H P + E + F++P++ L D Sbjct: 378 IKQLKQFFVLN----LIKGHMSPSEIETKY----ETFQYPKDWRQLHVLTLQIDSLEGTK 429 Query: 432 KPWHERHLLQEILSNLCLP-GPDAQIFGVEFSAKDQFALIISLPGHEAGSVQSRMEQVVE 490 E+ +L ++NL P+ + + LI+ + + + E Sbjct: 430 YAKEEKDVLLFSINNLVETLIPEVERLTPAL-LNNTVVLILLTNVDQEQKRDGFVREKAE 488 Query: 491 AIQTVIRDHSQLVPNIGVGMAYRDLARVNQSFIEAAAALEHRMIRRSGYVTYFEQLAERN 550 AI +R + +IGV + Y D+ + +++ E AL++R+ V +F LA + Sbjct: 489 AIMNEVRQQLDISVSIGVSLPYDDITKTQEAYDEGIEALKYRIKLGCQSVIFFSNLAHTH 548 Query: 551 APAADNFWIPRKSMLKLEQSLKQGNESVAVQMIADTIDTIKDEPL-----QIHLLRCICF 605 + + P++ +L +LK G++S + ID I + L QI LLR Sbjct: 549 SFHT---YYPKQQENELFDALKLGDKSNVKDHLDALIDGIFQKDLHPSQYQISLLR---- 601 Query: 606 DLLNAFLRIASELGMDGV-------FADMPGXXXXXXXXXXXXXXXXXXXXICGQVERNT 658 LLN +++ LG+D V D + ER Sbjct: 602 -LLNNTIQLLQTLGIDSVDVYDKKTLFDQLFSLQTIDEVKQWFFTKLIAPSVHTVAER-M 659 Query: 659 ETGESSLMDDILAYVDQQFADYTLSLEHVALKFAISTSYLSRSFKEKTGTNFSQYIWQRR 718 ++ ++ D I+ + +F D L+LE +A + + +YLS F+++T +FS+Y+ R Sbjct: 660 DSQYRTISDQIIHIIQNEF-DMELTLESIAERLHYNPNYLSSIFRKETNISFSEYLSSYR 718 Query: 719 VDEVIRLLENTSAPLKEIIEQVGYLDAPNFIRKFKKETGLTPGQYRK 765 + + L TS P++EI E++ Y ++ NFIR FKK+ G+TPG+YR+ Sbjct: 719 LAMAKKWLLETSMPIREIAERLCYGNSQNFIRSFKKKEGMTPGKYRQ 765 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 80.1 bits (196), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 86/302 (28%), Positives = 132/302 (43%), Gaps = 18/302 (5%) Query: 470 IISLPGHEAGSVQSRMEQVVEAIQTVIRDHSQLVP---NIGVGMAYRDLARVNQSFIEAA 526 I+ L +E G + EQVV IQ + + + P GVG YR L + S+ EA Sbjct: 226 ILMLTENENGMTKQEREQVV--IQLLHKVKQAVQPAKVKTGVGGIYR-LHFFSTSYREAL 282 Query: 527 AALEHRMIRRSGYVTYFEQLAERNAPAADNFWIPRKSMLKLEQSLKQGNESVAVQMIADT 586 AL+ +I +Y+ ++N + +P + KL +++K G+ A+Q Sbjct: 283 LALD--IIYDHKQASYY--FYDKNVKIRADEQLPIERENKLIEAIKSGDGEKALQAFDHY 338 Query: 587 IDTI---KDEPLQIHLLRCICFDLLNAFLRIASELGMDGVFADMPGXXXXXXXXXXXXXX 643 + I PL H +R L R+ +E+G+ + Sbjct: 339 VQAILRCSKHPL--HDMRKYLQQLFIILGRLLNEMGLH--WETAQDFARFSTVHQVTEHG 394 Query: 644 XXXXXXICGQVERNTETGESSLMDDILAYVDQQFADYTLSLEHVALKFAISTSYLSRSFK 703 I ++ T E SLM YV F + L+L+ +A +S Y+S+ FK Sbjct: 395 KSEILHIVRTLQEWRTTDEQSLMLLARDYVHDHFRE-PLTLDDLAKHIGLSPYYVSKLFK 453 Query: 704 EKTGTNFSQYIWQRRVDEVIRLLENTSAPLKEIIEQVGYLDAPNFIRKFKKETGLTPGQY 763 E+ FS+Y+ Q RV+ +LL T LKEI ++GY D F R FKK TG +P Y Sbjct: 454 ERFDLTFSEYVTQLRVEHAKQLLSLTQKSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDY 513 Query: 764 RK 765 RK Sbjct: 514 RK 515 >BH3679 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 257 Score = 76.6 bits (187), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 41/103 (39%), Positives = 60/103 (58%), Gaps = 1/103 (0%) Query: 663 SSLMDDILAYVDQQFADYTLSLEHVALKFAISTSYLSRSFKEKTGTNFSQYIWQRRVDEV 722 S + + L Y+D D + L+ VA ++ SYLS FKEKT FS+Y+ ++R+ Sbjct: 153 SDSIHEALHYIDAHL-DQKIGLKDVAKSVHLNPSYLSALFKEKTNMTFSEYLTRKRLQHA 211 Query: 723 IRLLENTSAPLKEIIEQVGYLDAPNFIRKFKKETGLTPGQYRK 765 LL +T P+ +I E+ GY A FI+ FK+ G+TP QYRK Sbjct: 212 KHLLVSTDRPISDIAEKCGYQTAKYFIKIFKEHEGMTPTQYRK 254 >BH0793 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 508 Score = 68.9 bits (167), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 37/113 (32%), Positives = 65/113 (57%), Gaps = 1/113 (0%) Query: 656 RNTETGESSLMDDILAYVDQQFADYTLSLEHVALKFAISTSYLSRSFKEKTGTNFSQYIW 715 + E S ++ +L ++ Q F+ LSL+ + F I+ YL + F+ + G +F++Y+ Sbjct: 395 QENEKNYSPIIQTVLQHIHQHFSQ-DLSLKTLGHSFHINPIYLGQLFQREVGCSFTKYLN 453 Query: 716 QRRVDEVIRLLENTSAPLKEIIEQVGYLDAPNFIRKFKKETGLTPGQYRKDHS 768 Q R+D +LL N+ +I ++VGY DA F ++FKK +TP ++RK H Sbjct: 454 QLRIDRAKKLLLNSYDRAGQIGKKVGYGDATYFYKQFKKYEAMTPTEWRKVHK 506 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 68.6 bits (166), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 36/106 (33%), Positives = 64/106 (60%), Gaps = 1/106 (0%) Query: 663 SSLMDDILAYVDQQFADYTLSLEHVALKFAISTSYLSRSFKEKTGTNFSQYIWQRRVDEV 722 SS + +LAY+++ ++ LSL +A F + SYLS F++ FS+Y+ + R+ + Sbjct: 399 SSSIQKMLAYIEEHHSE-PLSLSQLANYFHFNPSYLSAYFRQHHDEGFSEYLNKVRIRKA 457 Query: 723 IRLLENTSAPLKEIIEQVGYLDAPNFIRKFKKETGLTPGQYRKDHS 768 L++++ P+ EI VGY D F + FKK TG+ P +YR++++ Sbjct: 458 KEWLKSSTIPISEIYALVGYSDHSYFCKVFKKRTGMPPSRYRRENA 503 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.135 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 53,208,062 Number of extensions: 2238355 Number of successful extensions: 7499 Number of sequences better than 1.0e-05: 772 Number of HSP's gapped: 7518 Number of HSP's successfully gapped: 772 Length of query: 778 Length of database: 38,378,431 Length adjustment: 114 Effective length of query: 664 Effective length of database: 25,230,355 Effective search space: 16752955720 Effective search space used: 16752955720 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 120 (50.8 bits)