BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0370.0057.p
         (157 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH0949 [HE] COG0111 Phosphoglycerate dehydrogenase and related d...    73   2e-13
SA1679 [HE] COG0111 Phosphoglycerate dehydrogenase and related d...    62   2e-10
lin1792 [HE] COG0111 Phosphoglycerate dehydrogenase and related ...    60   1e-09
CAC0089 [HE] COG0111 Phosphoglycerate dehydrogenase and related ...    49   2e-06

>BH0949 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases
          Length = 316

 Score = 73.2 bits (178), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 56/100 (56%)

Query: 34  LAEAEIVIGWGKGISDTLLSAESPLRWVQAWSAGVEKLPLAAMENKGILLTNASGVHAEP 93
           L EA+++I +G+ +++  L A   L+W+   SAGVE+LP  A++ KGI++TNA G+HA P
Sbjct: 39  LEEADVLITYGEDVTEEHLQAAKKLKWIMVISAGVEQLPFQAIKEKGIIVTNAKGIHAIP 98

Query: 94  ITAVIFGFMLLFTRNLHTAVRNQLNRRWHSEGSESELTGK 133
           +       ML   RN    +  +  + W       EL G+
Sbjct: 99  MAEYTLSMMLQVARNAKRLISLEQEQTWDRRVPMIELNGQ 138


>SA1679 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases
          Length = 316

 Score = 62.4 bits (150), Expect = 2e-10,   Method: Compositional matrix adjust.
 Identities = 31/102 (30%), Positives = 57/102 (55%)

Query: 32  AQLAEAEIVIGWGKGISDTLLSAESPLRWVQAWSAGVEKLPLAAMENKGILLTNASGVHA 91
           + LA+ +I++G+  GI++  L     L+W+  ++ GV  LPL  + + GILLTN  GV A
Sbjct: 37  SDLADLDILVGYDGGINEAFLQRCPNLKWIAWFATGVNTLPLDYIADHGILLTNGKGVQA 96

Query: 92  EPITAVIFGFMLLFTRNLHTAVRNQLNRRWHSEGSESELTGK 133
           + ++  I  F+L   + +  +  NQ    + S+ +   L+G+
Sbjct: 97  KQLSEYILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQ 138


>lin1792 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases
          Length = 301

 Score = 60.1 bits (144), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 5/103 (4%), Positives = 17/103 (16%)

Query: 31  LAQLAEAEIVIGWGKGISDTLLSAESPLRWVQAWSAGVEKLPLAAMENKGILLTNASGVH 90
                +A+       GI          +            +     +     + +   V 
Sbjct: 34  SITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVI 93

Query: 91  AEPITAVIFGFMLLFTRNLHTAVRNQLNRRWHSEGSESELTGK 133
                        +    L       +      +  + +    
Sbjct: 94  FVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEKADLL 136


>CAC0089 [HE] COG0111 Phosphoglycerate dehydrogenase and related
           dehydrogenases
          Length = 318

 Score = 49.3 bits (116), Expect = 2e-06,   Method: Compositional matrix adjust.
 Identities = 29/120 (24%), Positives = 64/120 (53%), Gaps = 4/120 (3%)

Query: 18  GYTLTLGDGKAPDLAQLAE----AEIVIGWGKGISDTLLSAESPLRWVQAWSAGVEKLPL 73
           G+ + + + K+ D   L E    +E+++     +   +++++S L+ +     GV+ + L
Sbjct: 27  GHEIVIYNEKSTDTNVLKERVKDSEVIVLANMPLKAEVINSDSKLKMMSIAFTGVDHVEL 86

Query: 74  AAMENKGILLTNASGVHAEPITAVIFGFMLLFTRNLHTAVRNQLNRRWHSEGSESELTGK 133
           +A+ NK ++++NASG   E +T + FG +    RN+    +     +  +  S+S+L+GK
Sbjct: 87  SALNNKEVVVSNASGYSTESVTELTFGLVFSVLRNIVPLDKVTREGKTKNGFSQSDLSGK 146


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.315    0.132    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 11,109,996
Number of extensions: 385543
Number of successful extensions: 562
Number of sequences better than 1.0e-05: 4
Number of HSP's gapped: 564
Number of HSP's successfully gapped: 4
Length of query: 157
Length of database: 38,378,431
Length adjustment: 98
Effective length of query: 59
Effective length of database: 27,075,699
Effective search space: 1597466241
Effective search space used: 1597466241
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 111 (47.4 bits)