BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0048.p (308 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yhcH [V] COG1131 ABC-type multidrug transport system, ATPase ... 351 8e-97 lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase ... 302 4e-82 BS_ydbJ [V] COG1131 ABC-type multidrug transport system, ATPase ... 271 7e-73 CAC0138 [V] COG1131 ABC-type multidrug transport system, ATPase ... 251 9e-67 CAC0147 [V] COG1131 ABC-type multidrug transport system, ATPase ... 229 5e-60 >BS_yhcH [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 154 Score = 351 bits (901), Expect = 8e-97, Method: Compositional matrix adjust. Identities = 0/298 (0%), Positives = 0/298 (0%), Gaps = 4/298 (1%) Query: 8 VKPVASLMGVTKKIGSKTLVSDLTLDIPPGQIFGFLGPNGAGKTTTIRMMVGLISISRGD 67 + + + + Q G + +M Sbjct: 1 MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDNIFMNVMTFNTQSPVEK 60 Query: 68 ILICGRSIKDHFEEAVANIGAIVENPEMYKFLTGYQNLRQYARMVPGVNKKRIHEVVELV 127 D + + + + Y N++ I + Sbjct: 61 KAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQLCSTIDNEQAIILKPGMF 120 Query: 128 GLGQRIHDKVKTYSLGMRQRLGVAQALLHRPKLLILDEPTNGLDPQGIRELRDYLRRLCQ 187 Sbjct: 121 180 Query: 188 EEGTTVFVSSHLLSEMELMCDSVAIIQNGKLIDVKQLKAVGAEILPDGETLFEVSDPEAA 247 Sbjct: 181 -- 238 Query: 248 LALLGTGVL--KDGGVAVAADREVIAELNAKLVTGGIKVYGIRVLSRSLEDQFLEITG 303 Sbjct: 239 296 >lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 301 Score = 302 bits (774), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 160/292 (54%), Positives = 204/292 (69%), Gaps = 7/292 (2%) Query: 19 KKIGSKTLVSDLTLDIPPGQIFGFLGPNGAGKTTTIRMMVGLISISRGDILICGRSIKDH 78 KKI + ++ ++ ++ PG++FGFLGPNGAGKTTTIRM+VGLI + G ILI G+ I+ + Sbjct: 13 KKIRKREIIKGISFEVRPGEVFGFLGPNGAGKTTTIRMIVGLIKPTSGTILIGGKDIRKN 72 Query: 79 FEEAVANIGAIVENPEMYKFLTGYQNLRQYARMVPGVNKKRIHEVVELVGLGQRIHDKVK 138 F EA+ +G+IVENPE Y FLTG +NL +ARM P + K+RI EV ELVGL +RI+D+V Sbjct: 73 FTEAMRGLGSIVENPEFYTFLTGQENLAYFARMDPSIKKERIQEVTELVGLEKRINDRVS 132 Query: 139 TYSLGMRQRLGVAQALLHRPKLLILDEPTNGLDPQGIRELRDYLRRLCQEEGTTVFVSSH 198 TYSLGMRQRLG+AQALL PKLLILDEPTNGLDP GI E+RD++R L + EG +V VSSH Sbjct: 133 TYSLGMRQRLGIAQALLSSPKLLILDEPTNGLDPSGIHEMRDFIRALARNEGISVLVSSH 192 Query: 199 LLSEMELMCDSVAIIQNGKLIDVKQLKAVGAEILPDGETLFEVSDP-EAALALLG--TGV 255 LLSE+EL+CD VAI+ +G +I Q+ + +L L ++ P E A A L T V Sbjct: 193 LLSEIELLCDRVAIMTDGTIIKTDQV----SHLLSSRAQLRWLATPFEQAKAFLASVTEV 248 Query: 256 LKDGGVAVAADREVIAELNAKLVTGGIKVYGIRVLSRSLEDQFLEITGGEGI 307 DG V A E AE N +LV GI+V+ I SLED FLE+TGG I Sbjct: 249 EVDGEYLVTAVNERSAEWNEQLVAKGIQVHEIDKKKPSLEDLFLELTGGHSI 300 >BS_ydbJ [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 308 Score = 271 bits (694), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 139/300 (46%), Positives = 197/300 (65%), Gaps = 7/300 (2%) Query: 7 VVKPVASLMGVTKKIGSKTLVSDLTLDIPPGQIFGFLGPNGAGKTTTIRMMVGLISISRG 66 + +P+ + G+ KKIGSK ++ +++D+ G+I G LGPNG+GKTT IR++VGL+ + G Sbjct: 1 MAEPILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGKTTLIRIIVGLLKQNSG 60 Query: 67 DILICGRSIKDHFEEAVANIGAIVENPEMYKFLTGYQNLRQYARMVPGVNKKRIHEVVEL 126 + I G FE+A+ +GAIVENPE Y +LTG++NL+ +A M + +R+ EVVE Sbjct: 61 SVTISGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHFANMHKKIADERLDEVVER 120 Query: 127 VGLGQRIHDKVKTYSLGMRQRLGVAQALLHRPKLLILDEPTNGLDPQGIRELRDYLRRLC 186 VGL IHDKVKTYSLGMRQRLG+AQA+LHRPKLLILDEPTNGLDP G+++ RD+++ L Sbjct: 121 VGLTSAIHDKVKTYSLGMRQRLGIAQAILHRPKLLILDEPTNGLDPAGMKDFRDHIKELA 180 Query: 187 QEEGTTVFVSSHLLSEMELMCDSVAIIQNGKLIDVKQLKAVGAEILPDGETLFEVSDPEA 246 + EGT V ++HLL E+E +CD V IIQ G ++K ++ + + EV E Sbjct: 181 EMEGTAVLFATHLLREVEDLCDRVIIIQKG---EIKAEVSLQGTDQTTEKAIIEVQPQEK 237 Query: 247 ALALLGTGVL----KDGGVAVAADREVIAELNAKLVTGGIKVYGIRVLSRSLEDQFLEIT 302 AL L +DG + V +E I ELN LV + V+ I ++SLED+F++ T Sbjct: 238 ALNWLTGNQYQAESQDGTIVVEVAKENIPELNRSLVGQDLNVFSITPYTQSLEDEFIKAT 297 >CAC0138 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 312 Score = 251 bits (641), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 137/313 (43%), Positives = 192/313 (61%), Gaps = 31/313 (9%) Query: 11 VASLMGVTKKIGSKTLVSDLTLDIPPGQIFGFLGPNGAGKTTTIRMMVGLISISRGDILI 70 V + V K IG + ++ ++ + GQIFGFLGPNGAGKTTTIRM+VGLI + G I I Sbjct: 4 VLEVKDVKKHIGKREIIKGISFSVEEGQIFGFLGPNGAGKTTTIRMLVGLIKPNSGSIKI 63 Query: 71 CGRSIKDHFEEAVANIGAIVENPEMYKFLTGYQNLRQYARMVPGVNKKRIHEVVELVGLG 130 G I+ E+A++N+G IVENP+MY FLTG +NL QYA+M V+K+RI EV E++GL Sbjct: 64 MGHDIQKEKEKALSNVGCIVENPDMYGFLTGRENLIQYAKMYGSVSKERIDEVAEIIGLK 123 Query: 131 QRIHDKVKTYSLGMRQRLGVAQALLHRPKLLILDEPTNGLDPQGIRELRDYLRRLCQEEG 190 RI+DKVK YSLGM+QRLG+ QALL RPKLLILDEPTNGLDP GI + R +R + +E Sbjct: 124 DRINDKVKKYSLGMKQRLGLGQALLVRPKLLILDEPTNGLDPVGIMDFRRIVRLMAEENK 183 Query: 191 TTVFVSSHLLSEMELMCDSVAIIQNGKLIDVKQLKA------------------VGAEIL 232 + VF+SSH+L+E++ +CD+VA I G++ V+ K + E L Sbjct: 184 SAVFISSHILAEIQQVCDTVAFINGGEIKSVESTKESEGKGTKENFGIATSNINLAMETL 243 Query: 233 PDGETLFEVSDPEAALALLGTGVLKDGGVAVAADREVIAELNAKLVTGGIKVYGIRVLSR 292 ++EV + E ++ + +VIAE L+ ++V + Sbjct: 244 SKLPFVYEVKNNEDKIS---------AAIQYGTSPKVIAE----LMKNSVEVIEFYKEHK 290 Query: 293 SLEDQFLEITGGE 305 +LED+F++I GE Sbjct: 291 TLEDRFMQIVEGE 303 >CAC0147 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 318 Score = 229 bits (584), Expect = 5e-60, Method: Compositional matrix adjust. Identities = 125/310 (40%), Positives = 185/310 (59%), Gaps = 19/310 (6%) Query: 11 VASLMGVTKKIGSKTLVSDLTLDIPPGQIFGFLGPNGAGKTTTIRMMVGLISISRGDILI 70 V + + KK+G+K ++ ++ I G+I GFLG NGAGKTTTI+M+VGLI+ +G ++I Sbjct: 4 VLEVTDLYKKLGNKEIIKGISFSIKEGEILGFLGRNGAGKTTTIKMLVGLITPDKGSVMI 63 Query: 71 CGRSIKDHFEEAVANIGAIVENPEMYKFLTGYQNLRQYARMVPGVNKKRIHEVVELVGLG 130 G I EEA++ +GA+VENPE+Y +LTG QNL Q AR + K+ I ++ VGL Sbjct: 64 SGHDITKEAEEALSCVGAVVENPELYSYLTGRQNLEQVARFYKDITKEDIEKIGNTVGLS 123 Query: 131 QRIHDKVKTYSLGMRQRLGVAQALLHRPKLLILDEPTNGLDPQGIRELRDYLRRLCQEEG 190 R+ +KVK YSLGM+QRLG+A+AL+ +PKLLILDEPTNGLDP GI E R+ L++ +E Sbjct: 124 GRLDEKVKKYSLGMKQRLGLAEALISKPKLLILDEPTNGLDPTGIIEFRNLLKKQAKENK 183 Query: 191 TTVFVSSHLLSEMELMCDSVAIIQNGKLIDVKQLKAVGAEILPDG--------------- 235 +FVSSH+LSE+E +CD VA I G + + LK + + Sbjct: 184 MAIFVSSHILSEIEQLCDRVAFIDGGIIKSFETLKGTNKDHKTESFENVVIMTKEKDKCT 243 Query: 236 ETLFEVSD-PEAALALLGTGVLKDGGVAVAADREVIAELNAKLVTGGIKVYGIRVLSRSL 294 E L E+S + LA G+ A + + ++ + L I++ I ++L Sbjct: 244 EALKEISFIIDFKLADESNGIYT---FEAKAKLDSVPDITSSLAEKKIRIEQIYKRQQNL 300 Query: 295 EDQFLEITGG 304 ED+++E+ G Sbjct: 301 EDRYIELVNG 310 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,227,180 Number of extensions: 969768 Number of successful extensions: 8850 Number of sequences better than 1.0e-05: 2125 Number of HSP's gapped: 6392 Number of HSP's successfully gapped: 2345 Length of query: 308 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 202 Effective length of database: 26,153,027 Effective search space: 5282911454 Effective search space used: 5282911454 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)