BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0045.p (412 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BB0262 [M] COG0739 Membrane proteins related to metalloendopepti... 133 6e-31 TP0155 [M] COG0739 Membrane proteins related to metalloendopepti... 122 8e-28 BB0761 [M] COG0739 Membrane proteins related to metalloendopepti... 117 4e-26 TP0864 [M] COG0739 Membrane proteins related to metalloendopepti... 111 2e-24 ZyebA [M] COG0739 Membrane proteins related to metalloendopeptid... 110 3e-24 >BB0262 [M] COG0739 Membrane proteins related to metalloendopeptidases Length = 417 Score = 133 bits (334), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 65/134 (48%), Positives = 84/134 (62%), Gaps = 2/134 (1%) Query: 279 KARLAPAVLWPTQSKVITSSFGYRSDPFKGVAAYHSGIDIAGSIGDPIYAAMDGVV-TAA 337 K L ++P Q VITS +GYR DPF GV ++H+GIDIA PI A+ +GVV TA Sbjct: 285 KEVLGETFIYPVQG-VITSGYGYRPDPFTGVISFHNGIDIANLANTPIKASREGVVVTAG 343 Query: 338 EQMGARGKYIILQHDNGLETWYMHLNTMLVAPGTKVSKGQKIALLGNTGRSTGPHLHFQV 397 G GKYI++ H NG +T Y HLN+ V G KVS+G I +G+TG STG HLHF + Sbjct: 344 FNAGGYGKYIVISHSNGFQTLYAHLNSFAVKVGKKVSRGAVIGYMGSTGYSTGNHLHFTI 403 Query: 398 VKQNKPVNPLGYVQ 411 K K NP+ Y++ Sbjct: 404 FKNGKTENPMKYLR 417 >TP0155 [M] COG0739 Membrane proteins related to metalloendopeptidases Length = 371 Score = 122 bits (307), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 53/119 (44%), Positives = 77/119 (64%), Gaps = 1/119 (0%) Query: 289 PTQSKV-ITSSFGYRSDPFKGVAAYHSGIDIAGSIGDPIYAAMDGVVTAAEQMGARGKYI 347 P +S+ ++S +G+RSDPF G ++H+G+D+ G P+Y+A+ G+V G Y+ Sbjct: 243 PLRSRYYVSSRYGWRSDPFTGARSFHNGLDMVSRRGTPVYSALGGIVRTVGYSAVYGNYL 302 Query: 348 ILQHDNGLETWYMHLNTMLVAPGTKVSKGQKIALLGNTGRSTGPHLHFQVVKQNKPVNP 406 I+ H G +T Y HL T+LV+ GT+V+ KI LLG TGRSTGPHLHF + K +NP Sbjct: 303 IVGHHAGYQTLYGHLQTVLVSAGTRVTSATKIGLLGKTGRSTGPHLHFTIYKNGSAINP 361 >BB0761 [M] COG0739 Membrane proteins related to metalloendopeptidases Length = 295 Score = 117 bits (292), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 47/130 (36%), Positives = 83/130 (63%) Query: 282 LAPAVLWPTQSKVITSSFGYRSDPFKGVAAYHSGIDIAGSIGDPIYAAMDGVVTAAEQMG 341 L ++P + +++S FG+R+DPF G ++H+GID+A + +Y++ G+V A Sbjct: 166 LNANFIFPLKKFIVSSDFGFRNDPFTGNKSFHTGIDLAAPMNAEVYSSSSGIVIEAGYND 225 Query: 342 ARGKYIILQHDNGLETWYMHLNTMLVAPGTKVSKGQKIALLGNTGRSTGPHLHFQVVKQN 401 G ++++ H N +++ Y HLN V G V G+ + +G TGR+TGPHLHF+++K+N Sbjct: 226 LYGNFVVVGHKNNIKSLYGHLNLYSVKIGDFVKSGEFLGXVGQTGRATGPHLHFEILKKN 285 Query: 402 KPVNPLGYVQ 411 P+NPL +++ Sbjct: 286 IPINPLKFLK 295 >TP0864 [M] COG0739 Membrane proteins related to metalloendopeptidases Length = 546 Score = 111 bits (277), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 52/121 (42%), Positives = 74/121 (61%), Gaps = 1/121 (0%) Query: 287 LWPTQSKVITSSFGYRSDPFKGVAAYHSGIDIAGSIGDPIYAAMDGVVTAAEQMGARGKY 346 ++P + + TS FGYRSDPF G ++H+GID+A G + A +DG V G Y Sbjct: 422 MYPIRGRR-TSGFGYRSDPFSGKRSFHNGIDLAAPYGTQVKATLDGKVAEIGYSRIYGNY 480 Query: 347 IILQHDNGLETWYMHLNTMLVAPGTKVSKGQKIALLGNTGRSTGPHLHFQVVKQNKPVNP 406 +I+ H G +T Y HL++++V G +V +G I +G +GR+TGPHLHF V K VNP Sbjct: 481 LIIVHGGGYQTMYGHLSSVMVGRGARVVQGTTIGRVGASGRATGPHLHFSVFKNGSVVNP 540 Query: 407 L 407 L Sbjct: 541 L 541 >ZyebA [M] COG0739 Membrane proteins related to metalloendopeptidases Length = 419 Score = 110 bits (276), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 59/129 (45%), Positives = 79/129 (61%), Gaps = 3/129 (2%) Query: 282 LAPAVL-WPTQSKV-ITSSFG-YRSDPFKGVAAYHSGIDIAGSIGDPIYAAMDGVVTAAE 338 LA L +PT + I+S+F R++P G A H G+D A G P+ + DG V A+ Sbjct: 259 LAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGEVVVAK 318 Query: 339 QMGARGKYIILQHDNGLETWYMHLNTMLVAPGTKVSKGQKIALLGNTGRSTGPHLHFQVV 398 + GA G Y+ ++H T YMHL +LV PG KV +G +IAL GNTGRSTGPHLH++V Sbjct: 319 RSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGPHLHYEVW 378 Query: 399 KQNKPVNPL 407 + VNPL Sbjct: 379 INQQAVNPL 387 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.315 0.130 0.363 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 20,853,331 Number of extensions: 725589 Number of successful extensions: 2124 Number of sequences better than 1.0e-05: 118 Number of HSP's gapped: 2037 Number of HSP's successfully gapped: 118 Length of query: 412 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 303 Effective length of database: 25,807,025 Effective search space: 7819528575 Effective search space used: 7819528575 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 117 (49.7 bits)