BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0044.p (488 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2858 [I] COG1502 Phosphatidylserine/phosphatidylglycerophospha... 400 e-111 BS_ywiE [I] COG1502 Phosphatidylserine/phosphatidylglycerophosph... 329 7e-90 BS_ywnE [I] COG1502 Phosphatidylserine/phosphatidylglycerophosph... 327 2e-89 lin2646 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosph... 320 5e-87 SA1891 [I] COG1502 Phosphatidylserine/phosphatidylglycerophospha... 297 3e-80 >BH2858 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol ipin synthases and related enzymes Length = 184 Score = 400 bits (1027), Expect = e-111, Method: Compositional matrix adjust. Identities = 0/457 (0%), Positives = 0/457 (0%), Gaps = 6/457 (1%) Query: 34 EFRRPQRALAWLFIAFCCPPAGLLFYYFFGRDYWQSRKLHKRCISLFREIRAHLSGKIKL 93 + W L+ R+ + + I + Sbjct: 51 TLSAGDTLVVWKLDRLGRSMRHLVVLVEELRERGINFRSLTDSIDT-STPMGRFFFHVMG 109 Query: 94 VADAADSGNPHFADHKXXXXXXXXXXXXPVTGRNKCQVLFDGREAFEAMLDAMEAARDNI 153 + + + GR +A + + I Sbjct: 110 ALAEMERELIV---ERTKAGLETARAQGRIGGRRPKLTPEQWAQAGRLIAAGTPRQKVAI 166 Query: 154 HMEFYIFRDDEIGERFQDVMIRKSRQGVRVRLLCDGLGSHKLGRRFIRTLRNAGVEVHFF 213 Sbjct: 167 226 Query: 214 LPPLISLLDRRFNFRNHRKIIVVDGRVGFTGGLNIGDDYLGKDPKLGYWRDTHLRLEGDA 273 Sbjct: 227 286 Query: 274 VYSLQYIFLKDWRLATGEGMNHPRFF-PA-HKCTDQEAVLMVASGPDGALDASQEMYFAS 331 Sbjct: 287 346 Query: 332 IVAAKQRIWITSPYFIPDPTICRALKNAVLSGVDVRIIIPAIPDNRLVYYASLSYLENLQ 391 Sbjct: 347 406 Query: 392 DAGVKFYRYQKGFMHAKVMIIDDLLGTVGSANLDMRSFYSNFELTAVLLRPEVIAGLAAS 451 Sbjct: 407 466 Query: 452 VEQDLQHSEFIEPVIFRRRGNHVKLIESLCQLLSPLL 488 Sbjct: 467 503 >BS_ywiE [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol ipin synthases and related enzymes Length = 184 Score = 329 bits (843), Expect = 7e-90, Method: Compositional matrix adjust. Identities = 0/460 (0%), Positives = 0/460 (0%), Gaps = 16/460 (3%) Query: 34 EFRRPQRALAWLFIAFCCPPAGLLFYYFFGRDYWQSRKLHKRCISLFREIRAHLSGKIKL 93 + L ++ R + + + Sbjct: 52 LSAGDTLVVWKLDRLGRSMRHLVVLVEELRERGINFR--------SLTDSIDTSTPMGRF 103 Query: 94 VADAADSGNPHFA----DHKXXXXXXXXXXXXPVTGRNKCQVLFDGREAFEAMLDAMEAA 149 + + G + ++ + ++ A Sbjct: 104 FFHVMGA--LAEMERELIVERTKAGLETARAQGRIGGRRPKLTPEQWAQAGRLIAAGTPR 161 Query: 150 RDNIHMEFYIFRDDEIGERFQDVMIRKSRQGVRVRLLCDGLGSHKLGRRFIRTLRNAGVE 209 Sbjct: 162 221 Query: 210 VHFFLPPLISLLDRRFNFRNHRKIIVVDGRVGFTGGLNIGDDYLGKDPKLGYWRDTHLRL 269 Sbjct: 222 281 Query: 270 EGDAVYSLQYIFLKDWRLATGEGMNHPRFFPAHKCTDQEAVL-MVASGPDGALDASQEMY 328 Sbjct: 282 - 340 Query: 329 FASIVAAKQRIWITSPYFIPDPTICRALKNAVLSGVDVRIIIPAIPDNRLVYYASLSYLE 388 Sbjct: 341 400 Query: 389 NLQDAGVKFYRYQKGFMHAKVMIIDDLLGTVGSANLDMRSFYSNFELTAVLLRPEVIAGL 448 Sbjct: 401 460 Query: 449 AASVEQDLQHSEFIEPVIFRRRGNHVKLIESLCQLLSPLL 488 Sbjct: 461 500 >BS_ywnE [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol ipin synthases and related enzymes Length = 184 Score = 327 bits (839), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 0/464 (0%), Positives = 0/464 (0%), Gaps = 16/464 (3%) Query: 34 EFRRPQRALAWLFIAFCCPPAGLLFYYFFGRDY-------WQSRKLHKRCISLFREIRAH 86 + LL G + Sbjct: 26 GCELIFEDKISGTKSERPGLKKLLRTLSAGDTLVVWKLDRLGRSM----RHLVVLVEELR 81 Query: 87 LSGKIKLVADAADSGNPHFADHKXXXXXXXXXXXXPVTGRNKCQVLFDGREAFEAMLDAM 146 + + + A Sbjct: 82 ER---GINFRSLTDSIDTSTPMGRFFFHVMGALAEMERELIVERTKAGLETARAQGRIGG 138 Query: 147 EAARDNIHMEFYIFRDDEIGERFQDVMIRKSRQGVRVRLLCDGLGSHKLGRRFIRTLRNA 206 Sbjct: 139 198 Query: 207 GVEVHFFLPPLISLLDRRFNFRNHRKIIVVDGRVGFTGGLNIGDDYLGKDPKLGYWRDTH 266 Sbjct: 199 258 Query: 267 LRLEGDAVYSLQYIFLKDWRLATGEGMNH--PRFFPAHKCTDQEAVLMVASGPDGALDAS 324 Sbjct: 259 318 Query: 325 QEMYFASIVAAKQRIWITSPYFIPDPTICRALKNAVLSGVDVRIIIPAIPDNRLVYYASL 384 Sbjct: 319 378 Query: 385 SYLENLQDAGVKFYRYQKGFMHAKVMIIDDLLGTVGSANLDMRSFYSNFELTAVLLRPEV 444 Sbjct: 379 438 Query: 445 IAGLAASVEQDLQHSEFIEPVIFRRRGNHVKLIESLCQLLSPLL 488 Sbjct: 439 482 >lin2646 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol ipin synthases and related enzymes Length = 184 Score = 320 bits (819), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 0/463 (0%), Positives = 0/463 (0%), Gaps = 14/463 (3%) Query: 34 EFRRPQRALAWLFIAFCCPPAGLLFYYFFGRDYWQSRKLHKRCISLFRE-----IRAHLS 88 + LL G L + + Sbjct: 26 GCELIFEDKISGTKSERPGLKKLLRTLSAGD------TLVVWKLDRLGRSMRHLVVLVEE 79 Query: 89 GKIKLVADAA-DSGNPHFADHKXXXXXXXXXXXXPVTGRNKCQVLFDGREAFEAMLDAME 147 + + + + + A Sbjct: 80 LRERGINFRSLTDSIDTSTPMGRFFFHVMGALAEMERELIVERTKAGLETARAQGRIGGR 139 Query: 148 AARDNIHMEFYIFRDDEIGERFQDVMIRKSRQGVRVRLLCDGLGSHKLGRRFIRTLRNAG 207 Sbjct: 140 199 Query: 208 VEVHFFLPPLISLLDRRFNFRNHRKIIVVDGRVGFTGGLNIGDDYLGKDPKLGYWRDTHL 267 Sbjct: 200 259 Query: 268 RLEGDAVYSLQYIFLKDWRLATGEGM--NHPRFFPAHKCTDQEAVLMVASGPDGALDASQ 325 Sbjct: 260 319 Query: 326 EMYFASIVAAKQRIWITSPYFIPDPTICRALKNAVLSGVDVRIIIPAIPDNRLVYYASLS 385 Sbjct: 320 379 Query: 386 YLENLQDAGVKFYRYQKGFMHAKVMIIDDLLGTVGSANLDMRSFYSNFELTAVLLRPEVI 445 Sbjct: 380 439 Query: 446 AGLAASVEQDLQHSEFIEPVIFRRRGNHVKLIESLCQLLSPLL 488 Sbjct: 440 482 >SA1891 [I] COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol ipin synthases and related enzymes Length = 184 Score = 297 bits (761), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 0/368 (0%), Positives = 0/368 (0%), Gaps = 2/368 (0%) Query: 123 VTGRNKCQVLFDGREAFEAMLDAMEAARDNIHMEFYIFRDDEIGERFQDVMIRKSRQGVR 182 Sbjct: 127 186 Query: 183 VRLLCDGLGSHKLGRRFIRTLRNAGVEVHFFLPPLISLLDRRFNFRNHRKIIVVDGRVGF 242 Sbjct: 187 246 Query: 243 TGGLNIGDDYLGKDPKLGYWRDTHLRLEGDAVYSLQYIFLKDWR-LATGEGMNH-PRFFP 300 Sbjct: 247 306 Query: 301 AHKCTDQEAVLMVASGPDGALDASQEMYFASIVAAKQRIWITSPYFIPDPTICRALKNAV 360 Sbjct: 307 366 Query: 361 LSGVDVRIIIPAIPDNRLVYYASLSYLENLQDAGVKFYRYQKGFMHAKVMIIDDLLGTVG 420 Sbjct: 367 426 Query: 421 SANLDMRSFYSNFELTAVLLRPEVIAGLAASVEQDLQHSEFIEPVIFRRRGNHVKLIESL 480 Sbjct: 427 486 Query: 481 CQLLSPLL 488 Sbjct: 487 494 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.328 0.144 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 34,388,884 Number of extensions: 1335406 Number of successful extensions: 3211 Number of sequences better than 1.0e-05: 48 Number of HSP's gapped: 3057 Number of HSP's successfully gapped: 53 Length of query: 488 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 378 Effective length of database: 25,691,691 Effective search space: 9711459198 Effective search space used: 9711459198 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 118 (50.1 bits)