BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0043.p (302 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC1325 [S] COG1284 Uncharacterized conserved protein 309 3e-84 lin1422 [S] COG1284 Uncharacterized conserved protein 259 3e-69 BS_yqfU [S] COG1284 Uncharacterized conserved protein 246 3e-65 BS_ydeO [S] COG1284 Uncharacterized conserved protein 190 2e-48 BH2964 [S] COG1284 Uncharacterized conserved protein 162 8e-40 >CAC1325 [S] COG1284 Uncharacterized conserved protein Length = 285 Score = 309 bits (792), Expect = 3e-84, Method: Compositional matrix adjust. Identities = 157/288 (54%), Positives = 207/288 (71%), Gaps = 4/288 (1%) Query: 15 KPQKSEAFKRARLIQRIVMMVLGAAMMSVALEIFLVPNQLIDGGITGISIMISHIFHIPL 74 K + S F I +I++MVLG+ + SV LEIFL+PN +IDGGITGISI+ +H ++PL Sbjct: 2 KRKYSHVFT---FINKILLMVLGSVIASVGLEIFLIPNNIIDGGITGISIIANHFINLPL 58 Query: 75 GIILTLLNLPFLIIGYKQIGKTFALSTLFAVVLMSIGTQLLHPVAPLTGEPXXXXXXXXX 134 GI + LLNLPFLI+GYKQIGKTFA STLF+V+ +SIG +LHP+ +T + Sbjct: 59 GIFIFLLNLPFLIVGYKQIGKTFAFSTLFSVICLSIGVSVLHPIPGITHDILLATIFGGI 118 Query: 135 XXXXXXXXXXXXXXXXDGTEIVAILVSKKLPFSVGEVVMFFNLFILSGAGFVFGWNNAMF 194 DGTEIVAI++ K++ FS+GE+VMFFNLFIL +G VFGW+ AM+ Sbjct: 119 ILGAGVGLIIRNGGSLDGTEIVAIILDKRIGFSIGEIVMFFNLFILGASGIVFGWDRAMY 178 Query: 195 SLIAYYIAFKVIDVTLEGLDQSKSVWIISDKFRDIGEALTERLGRGVTYLDGEGGFSGDN 254 SLIAY+IAFK ID+T+EGL++SKSV ++SDK ++I ALT RLGRGVT L GEG + GD Sbjct: 179 SLIAYFIAFKTIDITVEGLNESKSVIVVSDKHKEISSALTSRLGRGVTLLHGEGAYKGDT 238 Query: 255 KKVIFVVITRLEEAKLKSIVEDWDSDAFIAIGNIHDVKGGRFKKKAIH 302 VI+VV++RLE AKL+SIV D+D +A I+I ++ DV G + KKAIH Sbjct: 239 TNVIYVVVSRLEIAKLRSIVHDFDENALISIASV-DVTGKMYGKKAIH 285 >lin1422 [S] COG1284 Uncharacterized conserved protein Length = 308 Score = 259 bits (663), Expect = 3e-69, Method: Compositional matrix adjust. Identities = 127/290 (43%), Positives = 198/290 (68%), Gaps = 2/290 (0%) Query: 8 FSNEEQKKPQKSEAFKRAR-LIQRIVMMVLGAAMMSVALEIFLVPNQLIDGGITGISIMI 66 F E K K E KR + + + +M+ GA +M V LE+FLV N+++DGG+ GISI+I Sbjct: 10 FMEELALKKVKQERRKRLKWFVYKFLMITFGAILMGVGLELFLVNNRILDGGVVGISIII 69 Query: 67 SHIFHIPLGIILTLLNLPFLIIGYKQIGKTFALSTLFAVVLMSIGTQLLHPVAPLTGEPX 126 S + +PLG++ +LN+PF IIGY++IGK FAL TL+ + +MSI T +LH + P+T + Sbjct: 70 SQLTPLPLGVLTFVLNIPFFIIGYRKIGKVFALFTLYGIAVMSIVTLVLHDMDPVTDDLL 129 Query: 127 XXXXXXXXXXXXXXXXXXXXXXXXDGTEIVAILVSKKLPFSVGEVVMFFNLFILSGAGFV 186 DGTEI++I+++ + PFS G+++MF N+ I AG V Sbjct: 130 LATVFGGMTLGLGVGLVIRNGGALDGTEIISIIINGRTPFSTGQIIMFINIVIFIVAGLV 189 Query: 187 FGWNNAMFSLIAYYIAFKVIDVTLEGLDQSKSVWIISDKFRDIGEALTERLGRGVTYLDG 246 F W+ AM+SLI Y++A+KVID+ ++G+D+SKS +IIS + +IG + E+LG+GVTYLD Sbjct: 190 FNWDRAMYSLITYFLAYKVIDIVIQGVDESKSAFIISRYYEEIGAEIMEQLGKGVTYLDA 249 Query: 247 EGGFSGDNKKVIFVVITRLEEAKLKSIVEDWDSDAFIAI-GNIHDVKGGR 295 GG+SGD +KV+FV+++R EE K+K+I+++ D DAF+A+ G++ +V+GG+ Sbjct: 250 TGGYSGDVRKVVFVIVSRFEEVKVKAILDEIDPDAFLAVGGSMSEVRGGK 299 >BS_yqfU [S] COG1284 Uncharacterized conserved protein Length = 293 Score = 246 bits (629), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 130/292 (44%), Positives = 185/292 (63%), Gaps = 7/292 (2%) Query: 15 KPQKSEAFKRARLIQRIVMMVLGAAMMSVALEIFLVPNQLIDGGITGISIMISHIF---- 70 K K E F I R+ M+++GAA +V++E+FL+PN IDGGI G+S+++ H+F Sbjct: 5 KQHKKETF--THFIFRVFMILVGAASAAVSIELFLIPNDFIDGGIIGVSLILDHLFMSNP 62 Query: 71 HIPLGIILTLLNLPFLIIGYKQIGKTFALSTLFAVVLMSIGTQLLHPVAPLTGEPXXXXX 130 + + +LN+PF+I GYK IGKTF +ST +V +++ LH V +T +P Sbjct: 63 FLNFAFSVVILNIPFMIFGYKYIGKTFLVSTFIGIVGLAVIESSLHHVEAITTQPILATV 122 Query: 131 XXXXXXXXXXXXXXXXXXXXDGTEIVAILVSKKLPFSVGEVVMFFNLFILSGAGFVFGWN 190 DGTEI+ IL++KKLPFSVGE VMF N+FI A FVFG Sbjct: 123 FGGLLLGFGVGLVIRNGGSMDGTEILGILLTKKLPFSVGEFVMFINVFIFIWAVFVFGPE 182 Query: 191 NAMFSLIAYYIAFKVIDVTLEGLDQSKSVWIISDKFRDIGEALTERLGRGVTYLDGEGGF 250 AM+S + YYIA K ID ++GLD++K+V I+S+++ +I +A+ RLGRG T L G+GG+ Sbjct: 183 QAMYSFMTYYIAMKTIDAVIQGLDETKAVIIVSEQYDEISDAILHRLGRGTTKLKGKGGY 242 Query: 251 SGDNKKVIFVVITRLEEAKLKSIVEDWDSDAFIAIGNIHDVKGGRFKKKAIH 302 + + K VI+ V+TRLE KLKSIV + D +AFI I N H+ +GG+F K AIH Sbjct: 243 TDEEKDVIYAVVTRLEVTKLKSIVFEVDQNAFITIMNTHETRGGKF-KNAIH 293 >BS_ydeO [S] COG1284 Uncharacterized conserved protein Length = 253 Score = 190 bits (483), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 0/262 (0%), Positives = 0/262 (0%), Gaps = 1/262 (0%) Query: 42 SVALEIFLVPNQLIDGGITGISIMISHIFHIPLGIILTLLNLPFLIIGYKQIGKTFALST 101 + + V I + + + + Sbjct: 29 EILMVDNAVRTHFEPYERHFKEIGFTENTIKKYLQCTNIQTVTVPVPAKFLRASNVPTGL 88 Query: 102 LFAVVLMSIGTQLLHPV-APLTGEPXXXXXXXXXXXXXXXXXXXXXXXXXDGTEIVAILV 160 L ++ + H + L + Sbjct: 89 LNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKPA 148 Query: 161 SKKLPFSVGEVVMFFNLFILSGAGFVFGWNNAMFSLIAYYIAFKVIDVTLEGLDQSKSVW 220 + + + + + + A +I V ++ Sbjct: 149 HPWKLKDICDCLYISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCG 208 Query: 221 IISDKFRDIGEALTERLGRGVTYLDGEGGFSGDNKKVIFVVITRLEEAKLKSIVEDWDSD 280 Sbjct: 209 268 Query: 281 AFIAIGNIHDVKGGRFKKKAIH 302 Sbjct: 269 290 >BH2964 [S] COG1284 Uncharacterized conserved protein Length = 277 Score = 162 bits (409), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 88/266 (33%), Positives = 144/266 (54%) Query: 33 MMVLGAAMMSVALEIFLVPNQLIDGGITGISIMISHIFHIPLGIILTLLNLPFLIIGYKQ 92 ++ +G+ +++V LE+ L PN L+DGG+T I+IM++ IF++P+ ++ LLN+P L + K Sbjct: 9 ILTIGSIIVAVGLELILAPNSLVDGGVTAIAIMLNAIFNLPIWLVFVLLNIPSLYVSGKY 68 Query: 93 IGKTFALSTLFAVVLMSIGTQLLHPVAPLTGEPXXXXXXXXXXXXXXXXXXXXXXXXXDG 152 +GK F + TL+A ++ + + P +T DG Sbjct: 69 MGKKFIIRTLYANIITAFALVNMAPFPAITTSEVLIVLYGGLLLGVGVGLVVKAGGAIDG 128 Query: 153 TEIVAILVSKKLPFSVGEVVMFFNLFILSGAGFVFGWNNAMFSLIAYYIAFKVIDVTLEG 212 TE++AI ++KK + + ++ N ILS A FVF AMFS+ ++I K ID L+G Sbjct: 129 TEMLAIWINKKYHIPISKFLLLVNALILSTAAFVFSLEQAMFSIAVFFIVTKTIDFILDG 188 Query: 213 LDQSKSVWIISDKFRDIGEALTERLGRGVTYLDGEGGFSGDNKKVIFVVITRLEEAKLKS 272 ++Q KSV IIS+K +IG+ L + LG +TYL GEGG+S +I+ + R K+K Sbjct: 189 INQGKSVMIISEKPEEIGQQLIDELGMTITYLYGEGGYSNQEVHLIYCITDRFRYPKIKE 248 Query: 273 IVEDWDSDAFIAIGNIHDVKGGRFKK 298 I D A + + + G + K Sbjct: 249 IALSIDPSAILEASFVTETTGVKRKS 274 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.325 0.142 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 19,266,218 Number of extensions: 736367 Number of successful extensions: 2131 Number of sequences better than 1.0e-05: 34 Number of HSP's gapped: 2093 Number of HSP's successfully gapped: 36 Length of query: 302 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 196 Effective length of database: 26,153,027 Effective search space: 5125993292 Effective search space used: 5125993292 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.6 bits) S2: 115 (48.9 bits)