BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0037.p (327 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll2074 [S] COG1273 Uncharacterized conserved protein 131 1e-30 SMb20686 [S] COG1273 Uncharacterized conserved protein 131 2e-30 SMb21406 [S] COG1273 Uncharacterized conserved protein 109 8e-24 mlr9623 [S] COG1273 Uncharacterized conserved protein 103 5e-22 SMb21407 [S] COG1273 Uncharacterized conserved protein 103 6e-22 >mll2074 [S] COG1273 Uncharacterized conserved protein Length = 302 Score = 131 bits (329), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 84/252 (33%), Positives = 141/252 (55%), Gaps = 9/252 (3%) Query: 12 WKGAISFGLVHVPVKMFSATEDKD-ISLRYIHKECGSPLSYVRKCPVCDKEVAWEE---I 67 WKG + LV PV+++ AT + IS +HK+ + ++ PV D E+ E + Sbjct: 7 WKGYLKLSLVSCPVRLYPATTTSERISFNQLHKKTHNRINM---KPV-DPELGLVERSDL 62 Query: 68 GKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGAN 127 KGYEY+ ++++ + +L+ + +S + I FVD E+D IY YYL+PD A A Sbjct: 63 VKGYEYEDKQYIIIDDADLDTVRIESNHTMNIEAFVDEGEVDVIYQDAPYYLAPDGAMAE 122 Query: 128 -AYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLP 186 + +L EAMR++GK+ IA++ + S+ + I + + + T+ P+EVR ++ G Sbjct: 123 ETFAVLREAMRKSGKLAIARLVLSSRERVVTIGARENGMFVCTLRNPNEVRGTAEYFGNI 182 Query: 187 EPGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQESN 246 G + + L++A+ LI Q T F+P Y D Y ++ +I K+ G + IA A + N Sbjct: 183 PAGKPDPEMLELAEALIKQKETTFDPKDYEDRYEIALMAMIREKLKGHKPIIAAAPERGN 242 Query: 247 VIDLMAALQASI 258 VI+LM AL+AS+ Sbjct: 243 VINLMDALKASL 254 >SMb20686 [S] COG1273 Uncharacterized conserved protein Length = 294 Score = 131 bits (329), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 85/252 (33%), Positives = 139/252 (55%), Gaps = 9/252 (3%) Query: 12 WKGAISFGLVHVPVKMFSATEDKD-ISLRYIHKECGSPLSYVRKCPVCDKEVAWEE---I 67 WKG I LV PV+++ AT + IS +HK+ + ++ PV D E+ E + Sbjct: 7 WKGYIRLSLVSCPVRLYPATSASERISFNQLHKDTHNRINM---KPV-DPELGLVERSDL 62 Query: 68 GKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGAN 127 KGYEY+ K+++ E +LE + +S + I FVD +D IY YYL+PD A A Sbjct: 63 VKGYEYEDKKYIIIEDSDLESVRIESNHTMNIEAFVDAGSVDVIYQDAPYYLAPDGAMAE 122 Query: 128 -AYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLP 186 + +L EA+R++GK+ IA++ + S+ + I + + T+ P+EVR + G Sbjct: 123 ETFVVLREALRRSGKLAIARLVLSSRERVVTIGPRETGMFVCTLRNPNEVRGTADYFGNI 182 Query: 187 EPGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQESN 246 G + + L +A+ LI Q +T F+P +Y D Y ++ +I K+ G + IA A + N Sbjct: 183 PVGKPDPEMLQLAEALIEQKTTTFDPKQYEDRYEVALMQMIREKLKGHKPIIAQAPERGN 242 Query: 247 VIDLMAALQASI 258 V++LM AL+AS+ Sbjct: 243 VVNLMDALKASL 254 >SMb21406 [S] COG1273 Uncharacterized conserved protein Length = 294 Score = 109 bits (272), Expect = 8e-24, Method: Compositional matrix adjust. Identities = 75/255 (29%), Positives = 123/255 (48%), Gaps = 3/255 (1%) Query: 5 AIIMHTVWKGAISFGLVHVPVKMFSATEDKD-ISLRYIHKECGSPLSYVRKCPVCDKEVA 63 A+ WKG + FG V PV +++AT D I+ +++E G+ + V K V Sbjct: 2 AVSARAQWKGYLRFGEVTAPVALYTATSTSDRIAFHTVNRETGNRVRREFIDSVSGKPVE 61 Query: 64 WEEIGKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQ 123 E+ KGYE ++V+ E EE+ +S K + + F+ E++ +YF K YYL+PD+ Sbjct: 62 KEDQVKGYEIGDERYVVLEPEEVASAVPESDKTLRVQAFIPCDEVEKVYFDKPYYLTPDK 121 Query: 124 AGANAYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQV- 182 G +A+ LL E MR+ IA+ + + +R L T+ + EVR + Sbjct: 122 MGTDAFALLREGMRKKKVAAIAQTVLFRRMRTILLRPHDKGLIATTLNFDYEVRSAKEAF 181 Query: 183 PGLPEPGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPAR 242 +P+ I + LD+AK +I F ++ D Y + DLI K+ G+ Sbjct: 182 KEIPDIKIEGEM-LDLAKHIIGMKKGTFSAEEFDDRYEAALADLIKAKLEGKSLPKRAPP 240 Query: 243 QESNVIDLMAALQAS 257 + S DL+ AL+ S Sbjct: 241 KVSKANDLLEALRQS 255 >mlr9623 [S] COG1273 Uncharacterized conserved protein Length = 288 Score = 103 bits (256), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 78/252 (30%), Positives = 122/252 (48%), Gaps = 11/252 (4%) Query: 12 WKGAISFGLVHVPVKMFSATEDKD-ISLRYIHKECGSPLSYVRKCPVCDKE----VAWEE 66 WKG I FG V V +++A + I+ +++ G+ VR+ D E V ++ Sbjct: 8 WKGYIKFGEVACAVALYTAASSSERIAFNTLNRATGN---RVRR-EFIDSETGDPVERDD 63 Query: 67 IGKGYEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSPDQAGA 126 KGYE + G +V+ E EE+ +S K + I FV EID +YF K YYL+PD+ GA Sbjct: 64 QVKGYEMENGDYVVLEPEEVAAAVPESDKTLKIEAFVPCDEIDDVYFDKPYYLAPDRMGA 123 Query: 127 NAYRLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQV-PGL 185 +A++LL + MRQ +A+ + + IR + L T+ + EVR + + Sbjct: 124 DAFKLLRDGMRQAKVAALARTVLFRRLRTVLIRPHGNGLIGTTLNFDYEVRSAKEAFADI 183 Query: 186 PEPGIVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHKIAGEEFHIAPARQES 245 PE I + LD+AK +I F+ + D Y + +L+ KI G A S Sbjct: 184 PEIKIEGEM-LDLAKHIIDTKKGSFDAKTFDDRYDAAVAELVKAKIEGRPLPKKKAPPPS 242 Query: 246 NVIDLMAALQAS 257 DL+ L+ S Sbjct: 243 KPSDLLETLRRS 254 >SMb21407 [S] COG1273 Uncharacterized conserved protein Length = 272 Score = 103 bits (256), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 75/262 (28%), Positives = 124/262 (47%), Gaps = 20/262 (7%) Query: 12 WKGAISFGLVHVPVKMFSAT-EDKDISLRYIHKECGSPLSYVRKCPVCDKEVAWEEIGKG 70 WKG + LV PV M AT E + + ++++ + + V KEV ++ KG Sbjct: 8 WKGYLKLSLVTCPVSMMPATSESEKVRFHTLNRKSNNRVVSRYVDAVTGKEVDEDDEVKG 67 Query: 71 YEYDKGKFVLFEKEELEQLTEQSTKNIAILDFVDLTEIDPIYFQKTYYLSP-DQAGANAY 129 YE + F++ E EELE + +S + I I FV I+ I+ +K +YL+P D+ G A+ Sbjct: 68 YERGENDFLVIEDEELESVALESARTIDIEKFVPRDTIEWIWLEKPHYLTPSDEVGHEAF 127 Query: 130 RLLMEAMRQTGKIGIAKISIRSKSSLAAIRVLADCLAIETIFYPDEVRPVSQVPGLPEPG 189 ++ +AM GI+++ I + + + + T+ Y DEVR G Sbjct: 128 SVIRDAMVAEKVAGISRLVIGRRERAVMLEPCGKGIVVWTLRYGDEVRKPENYFADIGDG 187 Query: 190 IVNDKELDMAKLLISQLSTPFEPGKYTDDYRQRMLDLITHK------------IAGEEFH 237 + K + + LI + S P+ P +D ++++L++I K GE H Sbjct: 188 DNDPKLMSLVTSLIEERSKPWNPNMVSDPVQEKLLEIIESKRKSAKKVAKPKAKEGEPVH 247 Query: 238 IAPARQESNVIDLMAALQASIE 259 NVIDLMAAL+ S+E Sbjct: 248 AG------NVIDLMAALKGSLE 263 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,042,606 Number of extensions: 785465 Number of successful extensions: 1812 Number of sequences better than 1.0e-05: 20 Number of HSP's gapped: 1775 Number of HSP's successfully gapped: 20 Length of query: 327 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 220 Effective length of database: 26,037,693 Effective search space: 5728292460 Effective search space used: 5728292460 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)