BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0026.p (565 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_ydiF [R] COG0488 ATPase components of ABC transporters with d... 649 0.0 BH0550 [R] COG0488 ATPase components of ABC transporters with du... 633 0.0 lin2179 [R] COG0488 ATPase components of ABC transporters with d... 578 e-165 L73239 [R] COG0488 ATPase components of ABC transporters with du... 548 e-155 SP1114 [R] COG0488 ATPase components of ABC transporters with du... 547 e-155 >BS_ydiF [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 531 Score = 649 bits (1673), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/539 (0%), Positives = 0/539 (0%), Gaps = 5/539 (0%) Query: 1 MLLQATGITKSYGIQSVLDGISLQVNEKERVGLVGVNGAGKSTFLQILAGEMSFDSGQIH 60 ++ I + S + ++ +E L G ++T L + + Sbjct: 2 KPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEATTLITALADKYKQTQTPR 61 Query: 61 KSKETTIGYLAQNSGLQSDKTIQEEMLAVFSPLIEAEAELRQLEADIADPGLADDPKRYE 120 + L + QE ++ ++ A+ Y Sbjct: 62 NLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRISELAEQN----KIIAYNYP 117 Query: 121 DLLERYARRSDWFKDHGGYEMNTRIRSVLHGMGFGEFPPETPIATLSGGQKTRLALARIL 180 + R+ G V G+ T + + Sbjct: 118 QGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKEDLIKLVEFDNKEYLYYK 177 Query: 181 LQAPDLLMLDEPTNHLDIETLTWLEDYLRSYAGGILVVSHDRYFLDRLVTTIVEIERHQS 240 APD+ + T + E V ++ + V +V+ Sbjct: 178 AIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNNGGIVMMQVQKMVKKATLHP 237 Query: 241 RKYTGNYSRYVDQKAAEYEIRLKQYEKQQEEISRMEDFVQRNIVRASTTKRAQSRRKALD 300 + + +L IS + +R R+AL Sbjct: 238 KSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLDDSTKLSLPLNQRKLVARRALF 297 Query: 301 KMERIDKPLGDLKKASFSFEPDFMSGKEVLQVRDVAVAFSEKAEPLFRNASFELRRGETA 360 +M + + A G + V A Sbjct: 298 EMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVETGP-IGGITSQGIAFGANVNTRAI 356 Query: 361 ALIGPNGIGKSTLLQCLTGTREPSTGTVNWGTKVKIAYYDQEQTRLNPRNTVLEELWSEY 420 + + K + +++ Sbjct: 357 LDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKFNGKIMGTGGFIDISATSKKIIFCG 416 Query: 421 PMLEEARIRTILGNFLFSGEDVLKKVAALSGGEKARVSLSKLMLRGANMLILDEPTNHLD 480 + + I L ++ K E L I + L Sbjct: 417 TLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEITFSGKIALERGLDVRYITERAVFTLK 476 Query: 481 LMSREVLESALIDFEGTLLFISHDRYFLNKMAERVLELHPGGIDQYLGNYDDYIEKKRE 539 Sbjct: 477 535 Score = 125 bits (313), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 0/349 (0%), Positives = 0/349 (0%), Gaps = 55/349 (15%) Query: 2 LLQATGITKSYGIQS-VLDGISLQVNEKERVGLVGVNGAGKSTFLQILAGEMSFDSGQIH 60 + + + + + Q Sbjct: 326 DDFILTVETGPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHG 385 Query: 61 KSKETTIGYLAQNSG-LQSDKTIQEEMLAVFSPLIEAEAELRQLEADIADPGLADDPKRY 119 +G ++++ Sbjct: 386 NVGVHKFNGKIMGTGGFIDISATSKKIIFCG-------------------TLT---AGS- 422 Query: 120 EDLLERYARRSDWFKDHGGYEMNTRIRSVLHGMGFGEFPPETPIATLSGGQKTRLALARI 179 + G + T + Sbjct: 423 ------------------------LKTEITDGKLNIVQEGRVKKFIRELPEITFSGKIAL 458 Query: 180 LLQAPDLLMLDEPTNHLDIETLTWLEDYLRSYAGGILVVSHDRYFLDRLVTTIVEIERHQ 239 + + L + L +E ++ D + +++ Sbjct: 459 ERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPELKLMDERLFI 518 Query: 240 SRKYTGNYSRYVDQKAAEYEIRLKQYEKQQEEISRMEDFVQRNIVRA--STTKRAQSRRK 297 Sbjct: 519 --- 575 Query: 298 ALDKMERIDKPLGDLKKASFSFEPDFMSGKEVLQVRDVAVAFSEKAEPL 346 Sbjct: 576 - 623 >BH0550 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 642 Score = 633 bits (1632), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/542 (58%), Positives = 409/542 (75%), Gaps = 3/542 (0%) Query: 1 MLLQATGITKSYGIQSVLDGISLQVNEKERVGLVGVNGAGKSTFLQILAGEMSFDSGQIH 60 ++LQ ITKS+G +++L I L+V +RV LVG NGAGKST L+I+A ++S+DSG + Sbjct: 2 IVLQCVNITKSFGAETILSNIKLEVKTGDRVALVGRNGAGKSTLLKIIADKLSYDSGDLI 61 Query: 61 KSKETTIGYLAQNSGLQSDKTIQEEMLAVFSPLIEAEAELRQLEADIADPGLADDPKRYE 120 K IGYL Q++GL+SD TI +EML+VF PL + E LR++E +A+P L ++ YE Sbjct: 62 IPKGVEIGYLEQHTGLESDLTIWDEMLSVFEPLQQMERRLRKMEEQMANPALLNNASSYE 121 Query: 121 DLLERYARRSDWFKDHGGYEMNTRIRSVLHGMGFGEFP-PETPIATLSGGQKTRLALARI 179 LLE Y FKD GGY+ IR+VL G+ F +FP ET IATLSGGQKTRLAL ++ Sbjct: 122 KLLEEYDSLQVEFKDRGGYQYEADIRNVLAGLQFADFPYHETKIATLSGGQKTRLALGKL 181 Query: 180 LLQAPDLLMLDEPTNHLDIETLTWLEDYLRSYAGGILVVSHDRYFLDRLVTTIVEIERHQ 239 LL PDLL+LDEPTNHLDI+TL+WLE YL +Y G IL+VSHDRYFLD+LVT + EI R + Sbjct: 182 LLTKPDLLILDEPTNHLDIDTLSWLEQYLSAYPGAILIVSHDRYFLDKLVTQVYEISRTK 241 Query: 240 SRKYTGNYSRYVDQKAAEYEIRLKQYEKQQEEISRMEDFVQRNIVRASTTKRAQSRRKAL 299 S KY GNYS Y+D+KA YE LK++EKQQ+E++++EDF+QRNI RASTTKRAQSRRKAL Sbjct: 242 STKYVGNYSHYLDEKALRYEQELKEFEKQQKEVAKLEDFIQRNIARASTTKRAQSRRKAL 301 Query: 300 DKMERIDKPLGDLKKASFSFEPDFMSGKEVLQVRDVAVAFSEKAEPLFRNASFELRRGET 359 ++M ++D+P D K ASF F+ + SG +VL+VRD+ FS +PLF +L RGE+ Sbjct: 302 ERMTKLDRPNSDEKSASFFFDIERQSGNDVLRVRDLT--FSYDGDPLFSRLDLDLNRGES 359 Query: 360 AALIGPNGIGKSTLLQCLTGTREPSTGTVNWGTKVKIAYYDQEQTRLNPRNTVLEELWSE 419 ALIGPNG GKSTLL+ LT + GT+ +G+ VKI YYDQEQ L+ VL ELW + Sbjct: 360 VALIGPNGAGKSTLLKLLTKKLQADQGTIEYGSHVKIGYYDQEQANLHSNKQVLYELWDD 419 Query: 420 YPMLEEARIRTILGNFLFSGEDVLKKVAALSGGEKARVSLSKLMLRGANMLILDEPTNHL 479 YP+L E IRT+LGNFLFSGEDVLK V+ LSGGEKAR++L+KLM+ AN+LI+DEPTNHL Sbjct: 420 YPLLPERDIRTVLGNFLFSGEDVLKVVSDLSGGEKARLALAKLMMEKANLLIMDEPTNHL 479 Query: 480 DLMSREVLESALIDFEGTLLFISHDRYFLNKMAERVLELHPGGIDQYLGNYDDYIEKKRE 539 DL S+EVLE+ALID+ GTLLF+SHDRYFLN+MA R++EL G +LG+YD Y+EKK+E Sbjct: 480 DLDSKEVLENALIDYPGTLLFVSHDRYFLNRMATRIIELDGGQPSVFLGDYDYYLEKKQE 539 Query: 540 LE 541 ++ Sbjct: 540 IK 541 >lin2179 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 650 Score = 578 bits (1489), Expect = e-165, Method: Compositional matrix adjust. Identities = 296/544 (54%), Positives = 397/544 (72%), Gaps = 1/544 (0%) Query: 1 MLLQATGITKSYGIQSVLDGISLQVNEKERVGLVGVNGAGKSTFLQILAGEMSFDSGQIH 60 +LLQ I+K +G + +LD I L+V +R+ LVG NGAGKST L+I+AG+MS+D G I Sbjct: 2 ILLQVQQISKFFGAEVILDNIKLEVKTGDRIALVGRNGAGKSTLLKIIAGKMSYDGGTIS 61 Query: 61 KSKETTIGYLAQNSGLQSDKTIQEEMLAVFSPLIEAEAELRQLEADIADPGLADDPKRYE 120 K K IGYLAQN+GL+S KTI +EML+VF L + EA+LR++E + +P L ++P++Y+ Sbjct: 62 KPKSVEIGYLAQNTGLESTKTIWDEMLSVFDSLRKMEADLRKMELRLGEPELYNNPEKYQ 121 Query: 121 DLLERYARRSDWFKDHGGYEMNTRIRSVLHGMGFGEFPPETPIATLSGGQKTRLALARIL 180 L+ Y FK+ GGY IRSVL+G+ F E IA+LSGGQKTRLALA++L Sbjct: 122 ALMTDYDTLQHTFKEVGGYTYEAEIRSVLNGLRFYPEDYEVEIASLSGGQKTRLALAKLL 181 Query: 181 LQAPDLLMLDEPTNHLDIETLTWLEDYLRSYAGGILVVSHDRYFLDRLVTTIVEIERHQS 240 L D+L+LDEPTNHLDIETL WLE YL++Y G +L+VSHDRYFLD++V + EI R + Sbjct: 182 LAKQDILVLDEPTNHLDIETLAWLETYLQNYHGSLLIVSHDRYFLDKVVNQVYEISRTRI 241 Query: 241 RKYTGNYSRYVDQKAAEYEIRLKQYEKQQEEISRMEDFVQRNIVRASTTKRAQSRRKALD 300 Y GNYS +V QK A+ E K+++KQQ++IS++EDFV RNIVRASTTKRAQSRRK L+ Sbjct: 242 DHYKGNYSSFVSQKQAKLEQMWKEFDKQQKQISKLEDFVARNIVRASTTKRAQSRRKQLE 301 Query: 301 KMERIDKPLGDLKKASFSFEPDFMSGKEVLQVRDVAVAFSEKAEPLFRNASFELRRGETA 360 KM+ + +P GD K A F F+ + +GK+VL V +++ ++ K + + N +FE++R ++ Sbjct: 302 KMDVLARPQGDEKSAHFGFQFEKQTGKDVLMVDKLSIGYA-KDKRIASNLTFEMKRQDSL 360 Query: 361 ALIGPNGIGKSTLLQCLTGTREPSTGTVNWGTKVKIAYYDQEQTRLNPRNTVLEELWSEY 420 AL+GPNGIGKSTLL+ L +G ++G VKI YYDQEQ +L TVL ELW +Y Sbjct: 361 ALVGPNGIGKSTLLKTLIRDIPALSGEFHFGAGVKIGYYDQEQAKLTSNKTVLMELWDDY 420 Query: 421 PMLEEARIRTILGNFLFSGEDVLKKVAALSGGEKARVSLSKLMLRGANMLILDEPTNHLD 480 P L E +RT LGNFLFS +DVLK V +LSGGEKAR++L+KL L AN+LILDEPTNHLD Sbjct: 421 PELNEVNVRTTLGNFLFSDDDVLKNVQSLSGGEKARLALAKLTLLEANVLILDEPTNHLD 480 Query: 481 LMSREVLESALIDFEGTLLFISHDRYFLNKMAERVLELHPGGIDQYLGNYDDYIEKKREL 540 + S+EVLE+ALIDFEGT+LF+SHDRYF+N++A +V+EL P +LG+YD Y EK E Sbjct: 481 IESKEVLEAALIDFEGTILFVSHDRYFINRIASKVVELAPEKATVFLGDYDYYQEKIAEA 540 Query: 541 EAIA 544 + +A Sbjct: 541 KELA 544 >L73239 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 635 Score = 548 bits (1411), Expect = e-155, Method: Compositional matrix adjust. Identities = 273/544 (50%), Positives = 385/544 (70%), Gaps = 10/544 (1%) Query: 1 MLLQATGITKSYGIQSVLDGISLQVNEKERVGLVGVNGAGKSTFLQILAGEMSFDSGQIH 60 +LLQ GI +++G + + I+ + + R+ LVG NGAGKST L+I+AG G + Sbjct: 2 ILLQGNGIARTFGDDVLFENINFSLQDHSRIALVGRNGAGKSTLLKIIAGVEEASRGTVS 61 Query: 61 KSKETTIGYLAQNSGLQSDKTIQEEMLAVFSPLIEAEAELRQLEADIADPGLADDPKRYE 120 K+K+ T+ YLAQ++GL S +TI EML+VF L + E +LRQ+E + + LA D Sbjct: 62 KTKDLTMNYLAQDTGLNSSRTIFAEMLSVFDSLRQMEKQLRQMELQMGE--LAGD--ELT 117 Query: 121 DLLERYARRSDWFKDHGGYEMNTRIRSVLHGMGFGEFPPETPIATLSGGQKTRLALARIL 180 L++RY S+ F+ G+ + I+SVL+G F + E I++LSGGQKTRLALA++L Sbjct: 118 ALMKRYDALSEEFRMKNGFTYESEIKSVLNGFRFDDAMWEREISSLSGGQKTRLALAKML 177 Query: 181 LQAPDLLMLDEPTNHLDIETLTWLEDYLRSYAGGILVVSHDRYFLDRLVTTIVEIERHQS 240 L+ P LL+LDEPTNHLDIETL WLE+YL++Y G +L+VSHDRYFLD++V ++E+ R + Sbjct: 178 LERPQLLILDEPTNHLDIETLAWLENYLKNYEGSLLIVSHDRYFLDKVVNEVLELSRGEL 237 Query: 241 RKYTGNYSRYVDQKAAEYEIRLKQYEKQQEEISRMEDFVQRNIVRASTTKRAQSRRKALD 300 +++GNYSRYV+Q+ + + LK +EKQQ+EI+++ED+V RN+VRASTTK AQSRRK L+ Sbjct: 238 TRFSGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVARNLVRASTTKMAQSRRKKLE 297 Query: 301 KMERIDKPLGDLKKASFSFEPDFMSGKEVLQVRDVAVAFSEK--AEPLFRNASFELRRGE 358 KMER+D P D K A+ +F P+ SG VL V + V + + + P+ + + R+GE Sbjct: 298 KMERLDAPTSDDKSANVTFTPEKTSGNVVLTVSEATVGYEDNRLSGPI----NIDERKGE 353 Query: 359 TAALIGPNGIGKSTLLQCLTGTREPSTGTVNWGTKVKIAYYDQEQTRLNPRNTVLEELWS 418 + A++GPNG+GK+TL++ + G G G V + YYDQEQ RL NTVL+ELW+ Sbjct: 354 SLAIVGPNGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGRLTASNTVLDELWN 413 Query: 419 EYPMLEEARIRTILGNFLFSGEDVLKKVAALSGGEKARVSLSKLMLRGANMLILDEPTNH 478 E+ +L E IR +LG FLFSG+DV K V LSGGEKAR+ L+KL + N L+LDEPTNH Sbjct: 414 EHRLLNEVEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMDHDNFLVLDEPTNH 473 Query: 479 LDLMSREVLESALIDFEGTLLFISHDRYFLNKMAERVLELHPGGIDQYLGNYDDYIEKKR 538 LD+ SREVLE+ALIDF GT+LF+SHDRYF+N++A +VLE+ P G ++LG+YD Y+EKK Sbjct: 474 LDIDSREVLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKE 533 Query: 539 ELEA 542 E++A Sbjct: 534 EVQA 537 >SP1114 [R] COG0488 ATPase components of ABC transporters with duplicated ATPase domains Length = 633 Score = 547 bits (1410), Expect = e-155, Method: Compositional matrix adjust. Identities = 273/537 (50%), Positives = 375/537 (69%), Gaps = 6/537 (1%) Query: 1 MLLQATGITKSYGIQSVLDGISLQVNEKERVGLVGVNGAGKSTFLQILAGEMSFDSGQIH 60 ++LQA I +S+ + + D I+LQV+E++R+ LVG NGAGKST L+IL GE SG+I+ Sbjct: 2 IILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKSTLLKILVGEEEPTSGEIN 61 Query: 61 KSKETTIGYLAQNSGLQSDKTIQEEMLAVFSPLIEAEAELRQLEADIADPGLADDPKRYE 120 K K+ ++ YLAQ+S +S+ TI +EML VF+ L E +LRQ+E ++ + D K Sbjct: 62 KKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTERQLRQMELEMGEKSGEDLDK--- 118 Query: 121 DLLERYARRSDWFKDHGGYEMNTRIRSVLHGMGFGEFPPETPIATLSGGQKTRLALARIL 180 L+ Y R S+ F+ GG+ IR++L+G F E + IA LSGGQ TRLALA++L Sbjct: 119 -LMSDYDRLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKIAELSGGQNTRLALAKML 177 Query: 181 LQAPDLLMLDEPTNHLDIETLTWLEDYLRSYAGGILVVSHDRYFLDRLVTTIVEIERHQS 240 L+ P+LL+LDEPTNHLDIET+ WLE+YL +Y+G +++VSHDRYFLD++ T +++ +H Sbjct: 178 LEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHDRYFLDKVATITLDLTKHSL 237 Query: 241 RKYTGNYSRYVDQKAAEYEIRLKQYEKQQEEISRMEDFVQRNIVRASTTKRAQSRRKALD 300 +Y GNYSR+V+ K + K YEKQQ+EI+ +EDFV RN+VRASTTKRAQSRRK L+ Sbjct: 238 DRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFVNRNLVRASTTKRAQSRRKQLE 297 Query: 301 KMERIDKPLGDLKKASFSFEPDFMSGKEVLQVRDVAVAFSEKAEPLFRNASFELRRGETA 360 KMER+DKP K A+ +F+ + SG VL V + AV + E L + + +LR+ Sbjct: 298 KMERLDKPEAGKKSANMTFQSEKTSGNVVLTVENAAVGYD--GEVLSQPINLDLRKMNAV 355 Query: 361 ALIGPNGIGKSTLLQCLTGTREPSTGTVNWGTKVKIAYYDQEQTRLNPRNTVLEELWSEY 420 A++GPNGIGKST ++ + G +G V++ YYDQ Q++L P NTVL+ELW+++ Sbjct: 356 AIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVGYYDQTQSKLTPSNTVLDELWNDF 415 Query: 421 PMLEEARIRTILGNFLFSGEDVLKKVAALSGGEKARVSLSKLMLRGANMLILDEPTNHLD 480 + E IR LG FLFSG+DV K V LSGGEKAR+ L+KL + N LILDEPTNHLD Sbjct: 416 KLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKARLLLAKLSMENNNFLILDEPTNHLD 475 Query: 481 LMSREVLESALIDFEGTLLFISHDRYFLNKMAERVLELHPGGIDQYLGNYDDYIEKK 537 + S+EVLE+ALIDF+GTLLF+SHDRYF+N++A VLEL G YLG+YD Y+EKK Sbjct: 476 IDSKEVLENALIDFDGTLLFVSHDRYFINRVATHVLELSENGSTLYLGDYDYYVEKK 532 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.135 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 41,095,536 Number of extensions: 1818127 Number of successful extensions: 35976 Number of sequences better than 1.0e-05: 1453 Number of HSP's gapped: 33696 Number of HSP's successfully gapped: 1952 Length of query: 565 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 453 Effective length of database: 25,461,023 Effective search space: 11533843419 Effective search space used: 11533843419 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 118 (50.1 bits)