BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0370.0010.p (327 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1448 [O] COG0225 Peptide methionine sulfoxide reductase 209 4e-54 BH2249 [O] COG0225 Peptide methionine sulfoxide reductase 186 4e-47 SA1257 [O] COG0225 Peptide methionine sulfoxide reductase 176 5e-44 VCA0615_2 [O] COG0229 Conserved domain frequently associated wit... 152 8e-37 L67708 [O] COG0225 Peptide methionine sulfoxide reductase 150 4e-36 >BH1448 [O] COG0225 Peptide methionine sulfoxide reductase Length = 346 Score = 209 bits (533), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 5/173 (2%), Positives = 17/173 (9%) Query: 7 KNRTELATFAGGCFWCMVKPFDELPGIVSVVSGYTGGHTENPXXXXXXXXXXXXXXAVQI 66 +R ++ F E + + Sbjct: 3 YHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 67 TYEPELFPYERLLDIYWQLIDPTDKGGQFMDRGYSYRTAIFVHNEXXXXXXXXXXXXXXX 126 + + K + Sbjct: 63 GLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQ 122 Query: 127 XXRFKDPIVTEILPAAPFYSAEALHQDYYKTHPLDYKLYLKGSGRDEFLEQHW 179 V + + + + Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIRY 175 >BH2249 [O] COG0225 Peptide methionine sulfoxide reductase Length = 346 Score = 186 bits (472), Expect = 4e-47, Method: Compositional matrix adjust. Identities = 5/173 (2%), Positives = 19/173 (10%) Query: 7 KNRTELATFAGGCFWCMVKPFDELPGIVSVVSGYTGGHTENPXXXXXXXXXXXXXXAVQI 66 + + + + + Sbjct: 2 QYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPET 61 Query: 67 TYEPELFPYERLLDIYWQLIDPTDKGGQFMDRGYSYRTAIFVHNEXXXXXXXXXXXXXXX 126 E + L + R + Sbjct: 62 QGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRL 121 Query: 127 XXRFKDPIVTEILPAAPFYSAEALHQDYYKTHPLDYKLYLKGSGRDEFLEQHW 179 + D + + + L + + Sbjct: 122 QTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIR 174 >SA1257 [O] COG0225 Peptide methionine sulfoxide reductase Length = 346 Score = 176 bits (446), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 5/171 (2%), Positives = 20/171 (11%) Query: 11 ELATFAGGCFWCMVKPFDELPGIVSVVSGYTGGHTENPXXXXXXXXXXXXXXAVQITYEP 70 + + S + + + Sbjct: 4 HRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQG 63 Query: 71 ELFPYERLLDIYWQLIDPTDKGGQFMDRGYSYRTAIFVHNEXXXXXXXXXXXXXXXXXRF 130 Y + + + I + Sbjct: 64 LTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQT 123 Query: 131 KDPIVTEILPAAPFYSAEALHQDYYKTHPLDYKLYLKGSGRDEFLEQHWNS 181 + ++ + + L E+ Sbjct: 124 DYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDTLDALAEYQRAGKIR 174 >VCA0615_2 [O] COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase Length = 346 Score = 152 bits (384), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 11/142 (7%), Positives = 25/142 (17%), Gaps = 1/142 (0%) Query: 182 PEDQKRLRNQLTRLQYEVTQHKASEPPYENAYWNEFRDGIYVDVISGDPLFSSADKFDSA 241 L L + SE GI + ++ + Sbjct: 6 IPHSS-LEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGL 64 Query: 242 TGWPSFTGPIAGGLIRREADYSGGEVRTALRSRLSGAYLGHLFFDGPEPAKQHYRVNSAA 301 T G + S + + + E + Sbjct: 65 TETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQTD 124 Query: 302 LRFIPKEELEANGLGRYVGVGK 323 + + + +G Sbjct: 125 YLDLYQVHWPQRPTNCFGKLGY 146 >L67708 [O] COG0225 Peptide methionine sulfoxide reductase Length = 346 Score = 150 bits (378), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 5/170 (2%), Positives = 19/170 (11%), Gaps = 2/170 (1%) Query: 10 TELATFAGGCFWCMVKPFDELPGIVSVVSGYTGGHTENPXXXXXXXXXXXXXXAVQITYE 69 + + S + + + Sbjct: 3 YHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQ 62 Query: 70 PELFPYERLLDIYWQLIDPTDKGGQFMDRGYSYRTAIFVHNEXXXXXXXXXXXXXXXXXR 129 Y + + + I + Sbjct: 63 GLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQ 122 Query: 130 FKDPIVTEILPAAPFYSAEALHQDYYKTHPLDYKLYLKGSGRDEFLEQHW 179 + ++ + + L Q Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT--LDALAEYQRA 170 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,296,079 Number of extensions: 983052 Number of successful extensions: 2229 Number of sequences better than 1.0e-05: 43 Number of HSP's gapped: 2180 Number of HSP's successfully gapped: 43 Length of query: 327 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 220 Effective length of database: 26,037,693 Effective search space: 5728292460 Effective search space used: 5728292460 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)