BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0369.0006.p (340 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH0366 [R] COG0523 Putative GTPases (G3E family) 200 3e-51 SA2368 [R] COG0523 Putative GTPases (G3E family) 155 8e-38 all1751 [R] COG0523 Putative GTPases (G3E family) 152 5e-37 BH1519 [R] COG0523 Putative GTPases (G3E family) 141 2e-33 SMc03799 [R] COG0523 Putative GTPases (G3E family) 139 7e-33 >BH0366 [R] COG0523 Putative GTPases (G3E family) Length = 311 Score = 200 bits (508), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 121/322 (37%), Positives = 186/322 (57%), Gaps = 19/322 (5%) Query: 7 VYILSGFLGSGKTTLLQRLLDHWKAQGLRPAVVMNELGEVNLDGLLVEQSVPMAEMLGGC 66 +YILSGFLGSGK+TLL+RL++ +A+G + V+MNELGEV++D +V + P+ EML GC Sbjct: 8 LYILSGFLGSGKSTLLKRLIEQEQARGNKIGVLMNELGEVSVDSSIVPKDTPLKEMLNGC 67 Query: 67 ICCSIRGDLSTELATLIKKESPDVVVIEATGAANPLEIVDAVTEISLYQLVELKGLITVV 126 ICC+I+G+LS +L + I++ DV+ IEATGAA+PLE+V+A T V ++G++TVV Sbjct: 68 ICCTIQGELSAQLQSFIEEYELDVIFIEATGAAHPLEVVEACTHPVFAGQVRVRGVLTVV 127 Query: 127 DAAHLIELYRSQQGATYRLMQEQIRCASVLILNKTDRVTPQEADEITVILRKWNAYAEIL 186 +A IE S + +LM+ Q+ A ++++NK D+VT + +++T ++ N A + Sbjct: 128 NARQWIEGKMSIK--IKKLMEAQVTFADLIVVNKVDQVTDAQVEQLTTSIKDLNPKAINI 185 Query: 187 PAVRCALEPEALLEGMGGIHAEARFQEDDEMQAGHAGDSSEAGAAVHGSHDHVMAYTHYF 246 P LEP +H+E R A + SE+ A VH H H+ Sbjct: 186 PTTFSNLEP---------VHSE-RLHH----AAAPSSRGSESKAHVH-EHLHLRTMAVPI 230 Query: 247 KRPVNSEEFEQFVKELPRDVYRAKGIVTFSDTSSRFLFQYAYREADFMKI-TPQGDVPDV 305 + PV+ E F+K + +YR KG + ++ FLF YAY + F + T Q P V Sbjct: 231 QHPVDRMELLSFLKGIQGQIYRVKGFIHLKESPGLFLFNYAYGDPMFERHRTDQAYAP-V 289 Query: 306 AVFIGEHFSSSELRTRLLQLEK 327 VFIG+ + L QL++ Sbjct: 290 LVFIGDDLDHQAIEEGLQQLQQ 311 >SA2368 [R] COG0523 Putative GTPases (G3E family) Length = 296 Score = 155 bits (392), Expect = 8e-38, Method: Compositional matrix adjust. Identities = 97/321 (30%), Positives = 157/321 (48%), Gaps = 35/321 (10%) Query: 5 MPVYILSGFLGSGKTTLLQRLLDHWKAQGLRPAVVMNELGEVNLDGLLVEQSVPMAEMLG 64 M + I+ GFLG GKTT+L LL + L+PAV+MNE G++++DG LV + +P++E+ Sbjct: 1 MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSVDGALVSEDIPLSELTE 60 Query: 65 GCICCSIRGDLSTELATLIKKESPDVVVIEATGAANPLEIVDAVTEISLYQLVELKGLIT 124 GCICC+++ D+S +L L KE PD+V IE +G A P+ ++DA L + +I Sbjct: 61 GCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLDACLTPILAPFTTITHMIG 120 Query: 125 VVDAA---HLIELYRSQQGATYRLMQEQIRCASVLILNKTDRVTPQEADEITVILRKWNA 181 V+DA+ H+ + QG Y EQ+ SVL +NK D + ++ L N Sbjct: 121 VIDASMYKHIKSFPKDIQGLFY----EQLAYCSVLFVNKIDSADVETTSKLLKDLEVINP 176 Query: 182 YAEILPAVRCALEPEALLEGMGGIHAEARFQEDDEMQAGHAGDSSEAGAAVHGSHDHVMA 241 A+I G+H + + E ++H + +H Sbjct: 177 EADI----------------QVGMHGSVTLPISVRQMTATSDNKHE---SLHKTINH--- 214 Query: 242 YTHYFKRPVNSEEFEQFVKE---LPRDVYRAKGIVTFSDTSSRFLFQYAYREADFMKITP 298 + + PV + E F+K LP +YR KG +TF DT+ +L Q+ + + + Sbjct: 215 --QFVQSPVTCTKAE-FIKRLACLPSHIYRLKGFMTFEDTTHTYLIQFTQGQYELTPVAF 271 Query: 299 QGDVPDVAVFIGEHFSSSELR 319 VP+ V IG+ S + + Sbjct: 272 SKKVPEYLVLIGKGISKEDYQ 292 >all1751 [R] COG0523 Putative GTPases (G3E family) Length = 323 Score = 152 bits (385), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 107/332 (32%), Positives = 173/332 (52%), Gaps = 33/332 (9%) Query: 4 AMPVYILSGFLGSGKTTLLQRLLDHWKAQGLRPAVVMNELGEVNLDG-LLVEQSVPMAEM 62 ++PV +L+G+LG+GKTTLL +L + G + AV++NE GEV +D L+++ + EM Sbjct: 9 SVPVTVLTGYLGAGKTTLLNHILTY--EHGKKVAVIVNEFGEVGIDNQLVIDADEEIFEM 66 Query: 63 LGGCICCSIRGDLSTELATLIKKESP-DVVVIEATGAANPLEIVDAV-TEISLYQLVELK 120 GCICC++RGDL ++ L+K+ D +VIE TG A+P ++ + + + L Sbjct: 67 NNGCICCTVRGDLIRIISNLMKRRDKFDHLVIETTGLADPAPVIQTFFVDEDMQSQLSLD 126 Query: 121 GLITVVDAAHLIELYRSQQGATYRLMQEQIRCASVLILNKTDRVTPQEADEITVILRKWN 180 ++T+VDA H+ + + + + QEQI A V++LNKTD VTP E DE+ +R N Sbjct: 127 AVVTLVDAKHIWQHWDADEA------QEQIAFADVILLNKTDLVTPSELDELEKRIRSMN 180 Query: 181 AYAEILPAVRCALEPEALLEGMGGIHAEARFQEDDEMQAGHAGDSSEAGAAVHGSHDHVM 240 A A+I L +ALL G+ A F D ++ D + G H D V Sbjct: 181 AIAKIYRTRNSELAMDALL----GVKA---FDLDRALEI----DPNFLGEDAHEHDDTVF 229 Query: 241 AYTHYFKRPVNSEEFEQFVKELPR----DVYRAKGIVTFSDTSSRFLFQ-----YAYREA 291 + + ++ E+ ++ EL R D++R KGI+ + +RF+FQ + R Sbjct: 230 SVALVQEGELDGEKLNAWISELLRTQGTDIFRMKGILNIAGEDNRFVFQGVHMIFDGRPD 289 Query: 292 DFMKITPQGDVPDVAVFIGEHFSSSELRTRLL 323 K P + VFIG + ++L+ L Sbjct: 290 RLWK--PNEKRKNELVFIGRNLDEAQLKQDFL 319 >BH1519 [R] COG0523 Putative GTPases (G3E family) Length = 320 Score = 141 bits (355), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 106/325 (32%), Positives = 171/325 (52%), Gaps = 19/325 (5%) Query: 5 MPVYILSGFLGSGKTTLLQRLLDHWKAQGLRPAVVMNELGEVNLDGLLVEQSVPMAEMLG 64 +PVY+ SGFLGSGKTT+L +L+ K GLRPA+V+NE GE+N++ L + E+L Sbjct: 2 IPVYLFSGFLGSGKTTVLLNVLNQLKEDGLRPAIVLNEAGEMNVEKELFANET-VVELLN 60 Query: 65 GCICCSIRGDLSTELATL--IKKESPDVVVIEATGAANPLEIVDAVTEISLYQLVELKGL 122 GCICC+I+ DL EL I S DV++IE TG ANP EI++ +T+ + + L+ + Sbjct: 61 GCICCTIQDDLKAELQRFLTINDRSVDVLLIEGTGIANPREIIEVLTDPPFIEQLALQSV 120 Query: 123 ITVVDAAHLIELYRSQQGATYRL---MQEQIRCASVLILNKTDRVTPQEADEITVILRK- 178 I ++DA+ +E YRS ++ + ++EQ+ +++L+LNK D V + ++ L+K Sbjct: 121 IGIIDASRYLE-YRSLFSSSKEIRAVLKEQVAESTLLLLNKQDLVDGRTLHKVEEKLKKD 179 Query: 179 WNAYAEILPAVRCALEPEALLEGMGGIHAEARFQEDDEMQAGHAGD-SSEAGAAVHGSHD 237 A IL + E LL + R + D ++G+ SS A + H H Sbjct: 180 KKPGATILFCSYGKVPTEELL--------KPRIKVDTGKDHAYSGEASSHASHSHHHHHH 231 Query: 238 HVMAYTHYFKRPVNSEEFEQFVKELPRDVYRAKGIVTFSDTSSRFLFQYAYREADFMKIT 297 + A ++PV +E ++++ + + RAKG V FQYA ++ K Sbjct: 232 DIQAIKLDLEQPVTEKELQRWLIDQGDQLIRAKGYVRLQGNDLLVHFQYASKQLSVRK-- 289 Query: 298 PQGDVPDVAVFIGEHFSSSELRTRL 322 + +VP + IG + L L Sbjct: 290 SKEEVPPCLILIGVDLNRETLAKSL 314 >SMc03799 [R] COG0523 Putative GTPases (G3E family) Length = 329 Score = 139 bits (350), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 100/291 (34%), Positives = 158/291 (54%), Gaps = 26/291 (8%) Query: 6 PVYILSGFLGSGKTTLLQRLLDHWKAQGLRPAVVMNELGEVNLDG-LLVEQSVPMAEMLG 64 PV +L+G+LG+GKTTLL R+L + G + AV++NE GEV +D L+V+ + EM Sbjct: 9 PVTVLTGYLGAGKTTLLNRILS--EPHGKKFAVIVNEFGEVGIDNDLIVDADEEVFEMNN 66 Query: 65 GCICCSIRGDLSTELATLIKK-ESPDVVVIEATGAANPLEIVDAV-TEISLYQLVELKGL 122 GCICC++RGDL + L+++ E D ++IE TG A+P + + + L + Sbjct: 67 GCICCTVRGDLIRIIEALMRRRERFDGILIETTGLADPAPVAQTFFVDEDVRSKTRLDSI 126 Query: 123 ITVVDAAHLI-ELYRSQQGATYRLMQEQIRCASVLILNKTDRVTPQEADEITVILRKWNA 181 ITVVDA HL+ E+ R+ + QEQ+ A +ILNKTD V+P+ + +R+ N Sbjct: 127 ITVVDAKHLLGEIDRAHEA------QEQLAFADTIILNKTDLVSPEGLQAVEDRIRRINP 180 Query: 182 YAEILPAVRCALEPEALLEGMGGIHAEARFQEDDEMQAGHAGDSSEAGAAVHGSHDHVMA 241 A IL RC LE +LL+ F D ++ D EA HV + Sbjct: 181 TAGILKTQRCNLEIASLLD-------RNAFDLDRILEV--EPDFLEADHDHEHDD-HVAS 230 Query: 242 YTHYFKRPVNSEEFEQFVKELPR----DVYRAKGIVTFSDTSSRFLFQYAY 288 ++ +RPV+ E+F ++++ R D+ R KGI+ F+ + R++ Q + Sbjct: 231 FSLVERRPVDPEKFFRWLQTTARAFGTDMLRMKGIIAFAGDTDRYVVQGVH 281 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.135 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,110,980 Number of extensions: 969246 Number of successful extensions: 4855 Number of sequences better than 1.0e-05: 54 Number of HSP's gapped: 4685 Number of HSP's successfully gapped: 55 Length of query: 340 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 233 Effective length of database: 26,037,693 Effective search space: 6066782469 Effective search space used: 6066782469 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)