BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0368.0020.p
         (286 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH3016 [M] COG0739 Membrane proteins related to metalloendopepti...    73   5e-13
BS_spoIVFA [M] COG0739 Membrane proteins related to metalloendop...    67   3e-11

>BH3016 [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 260

 Score = 73.2 bits (178), Expect = 5e-13,   Method: Compositional matrix adjust.
 Identities = 50/205 (24%), Positives = 93/205 (45%), Gaps = 14/205 (6%)

Query: 87  FMRRTIASIVVFGAVWGIFAIQQPWALKVQAFITDALSRDMDFAAAQVWYEEHFSGAPAF 146
            + RT+ SI +F  +  +F         ++A +  A  ++  FAA   WYE+ F    A 
Sbjct: 65  LLFRTLISICLFLVIAIVFQSNAAPLQPLRAGVEQAFEQEFQFAAIAHWYEQQFGQPLAL 124

Query: 147 IP-----IFGGEDQPAEKVTAAHGLSTPLAGSIVRPFAATMNGVEIMPAEASNGTLTVKS 201
           IP       G  DQ  E++      + P +G I   F     GV +   E   G   V++
Sbjct: 125 IPSNDQFALGDPDQDEERMV----FAVPASGVITESFEQNGRGVLV---ETGVGA-EVEA 176

Query: 202 VDTGRVLSVAKEAQGGIRITVRHTGDITAEYGHLSGTKLAADDWVQSGDAVGWLEETENA 261
             +G V+ +    +G + +T++H     + YG +    +   D +++G  +G     E+ 
Sbjct: 177 AKSGYVIEINNSEEGKM-VTLQHYDGSESIYGMIDNVAVNVYDHIEAGTKIGTASRAEDG 235

Query: 262 SVPLLFFAIMKDKTYIDPAEVVSFD 286
              + +FA+ + + Y+DP++V+ FD
Sbjct: 236 EKGVYYFALKQGENYVDPSDVIRFD 260


>BS_spoIVFA [M] COG0739 Membrane proteins related to metalloendopeptidases
          Length = 264

 Score = 67.4 bits (163), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 43/174 (24%), Positives = 87/174 (50%), Gaps = 10/174 (5%)

Query: 114 KVQAFITDALSRDMDFAAAQVWYEEHFSGAPAFI-PIFGGEDQPAEKVTAAHGLSTPLAG 172
           +++  +      +  FA+A  W+E  F    AF+ P    ++Q   ++     L  P +G
Sbjct: 100 QIKPAVAKTFETEFQFASASHWFETKFGNPLAFLAPEHKNKEQ---QIEVGKDLIAPASG 156

Query: 173 SIVRPFAATMNGVEIMPAEASNGTLTVKSVDTGRVLSVAKEAQGGIRITVRHTGDITAEY 232
            + + F     G+++   E S+    + SV  G V+ V+K++Q G+ + V+H  +  + Y
Sbjct: 157 KVQQDFQDNGEGIKV---ETSSDK--IDSVKEGYVVEVSKDSQTGLTVKVQHADNTYSIY 211

Query: 233 GHLSGTKLAADDWVQSGDAVGWLEETENASVPLLFFAIMKDKTYIDPAEVVSFD 286
           G L    +A  D+V  G  +G + + ++ +  + +FA+     +IDP +V+SF+
Sbjct: 212 GELKDVDVALYDFVDKGKKLGSI-KLDDHNKGVYYFAMKDGDKFIDPIQVISFE 264


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.317    0.134    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 21,817,468
Number of extensions: 952704
Number of successful extensions: 1689
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 1694
Number of HSP's successfully gapped: 2
Length of query: 286
Length of database: 38,378,431
Length adjustment: 105
Effective length of query: 181
Effective length of database: 26,268,361
Effective search space: 4754573341
Effective search space used: 4754573341
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 115 (48.9 bits)