BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0368.0019.p (280 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_spoIVFB [R] COG1994 Zn-dependent proteases 87 3e-17 MTH816_1 [R] COG1994 Zn-dependent proteases 86 7e-17 alr3900_1 [R] COG1994 Zn-dependent proteases 76 8e-14 SMa1126_1 [R] COG1994 Zn-dependent proteases 74 2e-13 SMb20925_1 [R] COG1994 Zn-dependent proteases 69 8e-12 >BS_spoIVFB [R] COG1994 Zn-dependent proteases Length = 288 Score = 86.7 bits (213), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 74/276 (26%), Positives = 121/276 (43%), Gaps = 14/276 (5%) Query: 7 IQLALHPLFVLIMLLSVVTGQFLELLTLFTIVFIHEMGHVCAALLCGVQVKSVQLLPFGG 66 +++ +HP +I L ++TG LL L IV IHE+GH A+ ++K V LLPFGG Sbjct: 9 LKIHVHPFLWIIAALGLLTGHMKALLCLLLIVLIHELGHAALAVFFSWRIKRVFLLPFGG 68 Query: 67 VAVMEDHGRLTAVREMGIAIAGPLQNVLLIVMAYGLRQTGYGTSAFLDYFIQANAIIALF 126 +E+HG E + IAGPLQ++ L A+ L + + F N I Sbjct: 69 TVEVEEHGNRPLKEEFAVIIAGPLQHIWLQFAAWMLAEVSVIHQHTFELFTFYNLSILFV 128 Query: 127 NLLPVLPLDGGKIFQAMXXXXXXXXXXXXWCGRVSIAASVLVVGYAMXXXXXXXXXXXXX 186 NLLP+ PLDGGK+ + + S+ +L+ + + Sbjct: 129 NLLPIWPLDGGKLLFLLFSKQLPFQKAHRLNLKTSLCFCLLLGCWVL----FVIPLQISA 184 Query: 187 XMIGAFLLYSNLTDQRNLPYRFVSFLMNREAVYERYQQSGSAARPIVAFSAKPLDDILRL 246 ++ FL S + R Y V FL+ ERY ++ + K D + + Sbjct: 185 WVLFVFLAVSLFEEYRQRHYIHVRFLL------ERYYGKNRELEKLLPLTVKAEDKVYHV 238 Query: 247 ---FKRNQYHFIYVMNEDKSIVAVVPEQKLISSYFG 279 FKR H I ++ + ++ + E +++ +YF Sbjct: 239 MAEFKRGCKHPI-IIEKSGQKLSQLDENEVLHAYFA 273 >MTH816_1 [R] COG1994 Zn-dependent proteases Length = 258 Score = 85.9 bits (211), Expect = 7e-17, Method: Compositional matrix adjust. Identities = 14/153 (9%), Positives = 28/153 (18%), Gaps = 17/153 (11%) Query: 4 IRGIQLALHPLFVLIML-------LSVVTGQFLELLTL-FTIVFIHEMGHVCAALLCGVQ 55 + + + VT ++ + G + Sbjct: 9 EGLRRTRIDEYLEKELERAGYGGMDVQVTPMGTMVVVYAERPGMVIGRGGKTVRAITQKL 68 Query: 56 VKSVQLLPFGGVAVMEDHGRLTAVREMGIAIAGPLQNVLLIVMA-----YGLRQTGYGTS 110 L D L + M IA LQ + + + Sbjct: 69 KNKFDLENPQVEVKEVDVPELNP-KIMAHKIAAMLQRGMHFRRVAYTTMRRIMA---AGA 124 Query: 111 AFLDYFIQANAIIALFNLLPVLPLDGGKIFQAM 143 ++ I A K + Sbjct: 125 QGVEVTISGKIRGARSATAKFTDGYIKKCGEPS 157 >alr3900_1 [R] COG1994 Zn-dependent proteases Length = 237 Score = 75.9 bits (185), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 52/155 (33%), Positives = 82/155 (52%), Gaps = 19/155 (12%) Query: 6 GIQLALHPLFVLIMLLSVV---------------TGQFLELLTLFTIVFIHEMGHVCAAL 50 GI L L PL+ +I+ L+ + T + L LF V +HE+GH AA Sbjct: 13 GIPLFLDPLWFVILGLATLNFGVAYQEWGTVTAWTAGLIMSLLLFGSVLLHELGHSLAAR 72 Query: 51 LCGVQVKSVQLLPFGGVAVMEDHGRLTAVREMGIAIAGPLQNV---LLIVMAYGLRQTGY 107 G++V S+ L FGG+A +E+ + T + +AIAGPL ++ LL+ + + Sbjct: 73 SQGIKVNSITLFLFGGIAAIEEESK-TPGKAFQVAIAGPLVSIGLFLLLRLGSTVVSDSS 131 Query: 108 GTSAFLDYFIQANAIIALFNLLPVLPLDGGKIFQA 142 S + + N ++ALFNL+P LPLDGG++ +A Sbjct: 132 PVSMMVGDLARINLVVALFNLIPGLPLDGGQVLKA 166 >SMa1126_1 [R] COG1994 Zn-dependent proteases Length = 229 Score = 74.3 bits (181), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 42/123 (34%), Positives = 69/123 (56%), Gaps = 11/123 (8%) Query: 31 LLTLFTIVFIHEMGHVCAALLCGVQVKSVQLLPFGGVAVMEDHGRLTAVREMGIAIAGPL 90 +L++F V +HE GH+ AA G++ + LLP GGVA +E + E+ IA+AGPL Sbjct: 48 ILSVFVCVVLHEFGHIAAARRFGIKTPDITLLPIGGVARLERNPS-EPREELLIAVAGPL 106 Query: 91 QNVLLIVM-------AYGLRQTGYGTSAFLDYFIQ---ANAIIALFNLLPVLPLDGGKIF 140 NV++ + GL Q +D+F++ N + LFN++P P+DGG++ Sbjct: 107 VNVVIAALLIAVIGGVAGLEQLVRPQDPQIDFFVRLAGVNIFLVLFNMIPAFPMDGGRVL 166 Query: 141 QAM 143 +A+ Sbjct: 167 RAI 169 >SMb20925_1 [R] COG1994 Zn-dependent proteases Length = 230 Score = 68.9 bits (167), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 42/121 (34%), Positives = 64/121 (52%), Gaps = 10/121 (8%) Query: 31 LLTLFTIVFIHEMGHVCAALLCGVQVKSVQLLPFGGVAVMEDHGRLTAVREMGIAIAGPL 90 ++ +F V +HE GH+ AA G++ + LLP GGVA +E +E IAIAGPL Sbjct: 48 IVAVFVCVVLHEFGHIAAARRFGIKTPDITLLPIGGVARLERMPEEPG-QEFVIAIAGPL 106 Query: 91 QNV------LLIVMAYGLRQTG---YGTSAFLDYFIQANAIIALFNLLPVLPLDGGKIFQ 141 NV + I+ + G+ Q S FL N + +FN++P P+DGG++ + Sbjct: 107 VNVAIAAVLIAILGSSGMEQIAGVEDPQSGFLARLAGVNVFLVIFNMIPAFPMDGGRVLR 166 Query: 142 A 142 A Sbjct: 167 A 167 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.331 0.144 0.423 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,673,192 Number of extensions: 597489 Number of successful extensions: 1246 Number of sequences better than 1.0e-05: 13 Number of HSP's gapped: 1231 Number of HSP's successfully gapped: 13 Length of query: 280 Length of database: 38,378,431 Length adjustment: 105 Effective length of query: 175 Effective length of database: 26,268,361 Effective search space: 4596963175 Effective search space used: 4596963175 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 115 (48.9 bits)