BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0359.0022.p (315 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0464 [K] COG2378 Predicted transcriptional regulator 113 4e-25 mlr3764 [K] COG2378 Predicted transcriptional regulator 108 1e-23 SMc02902 [K] COG2378 Predicted transcriptional regulator 107 3e-23 lin2535 [K] COG2378 Predicted transcriptional regulator 103 4e-22 mll3208 [K] COG2378 Predicted transcriptional regulator 103 5e-22 >lin0464 [K] COG2378 Predicted transcriptional regulator Length = 310 Score = 113 bits (282), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 89/312 (28%), Positives = 146/312 (46%), Gaps = 24/312 (7%) Query: 3 KTERQLAITLELQRSKMHRAEDLAAQFETSVRTIYRDIQALSEAGVPIIGAPGQ--GYSL 60 K +R ++I L L + A++LA +FE S+RTIYRDI A+ AGVPI PG G+ + Sbjct: 2 KVDRLMSIVLILLDKERISAQELADRFEVSLRTIYRDIDAIDLAGVPIRSTPGVGGGFEI 61 Query: 61 MEGYFLPPVGFTAEEAVALLMGTDFIEQRLDAEYGSVSKSARRKIEAVLPEPVRAESARV 120 M Y + F+ + A+LMG + + G +A KI++ +P RA+ + Sbjct: 62 MPDYKMDSKVFSTADLSAILMGLSSLSNMVR---GDELINALAKIKSFIPAD-RAKEIEL 117 Query: 121 RDTMRLLHAGEPVTGRKEKDYLGQIRRAILERHRLSFTYLKKMPEADGSRKSSREADPYG 180 + + + + ++ I+ A+ E L+F Y+ A K+ R +PY Sbjct: 118 KANQIYIDLSQWTGNNNIQPHVEIIKVALQENKLLTFEYI-----AHQGNKTVRIVEPYQ 172 Query: 181 LALVQGNWTLVARCGLRQDIRHFRLSRMTELAVLEERFSIPAGFNLSRYRPP----DDXX 236 L + +W L C R D R FRLSRM+ L +LE+ F+ L ++ P +D Sbjct: 173 LVMKSSHWYLYGYCQNRNDFRLFRLSRMSGLQILEDTFT------LRDFQKPQLEMEDIV 226 Query: 237 XXXXXXXXXXIADKMIETVNYYLETTEEREDG---LLVTFRIRQLEELLPYILSWGGEAE 293 I +I+ V Y DG +V+F + E +LS+G + E Sbjct: 227 AIMQIEIKIRIHQSIIDRVLDYCSYENFYPDGEEHYIVSFPFIENEYHYDILLSFGDKCE 286 Query: 294 VLEPVSLRRRVR 305 LEP+ +R +++ Sbjct: 287 CLEPLHVREKMK 298 >mlr3764 [K] COG2378 Predicted transcriptional regulator Length = 239 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 74/229 (32%), Positives = 107/229 (46%), Gaps = 10/229 (4%) Query: 1 MNKTERQLAITLELQRSKMHRAEDLAAQFETSVRTIYRDIQALSEAGVPIIGAPGQGYSL 60 M + +R I L+ ++ A+ L E S RTIYRDI L GVPI G G GY + Sbjct: 1 MRRADRLFQIVQHLRGGRLVTAQKLGTWLEVSERTIYRDIADLQSTGVPIDGEAGVGYMM 60 Query: 61 MEGYFLPPVGFTAEEAVALLMGTDFIEQRLDAEYGSVSKSARRKIEAVLPEPVRAESARV 120 EG+ LPP+ FT +E VAL+ G + A + A KI AVLP+ + AR Sbjct: 61 REGFDLPPLMFTRDEIVALVAGARMVRAFGGAAMARAADEALVKIGAVLPDTEKDRIART 120 Query: 121 RDTMRLLHAGEPVTGRKEKDYLGQIRRAILERHRLSFTYLKKMPEADGSRKSSREADPYG 180 +H V ++ + I RA+ +R L+ Y + R ++R+ P G Sbjct: 121 E-----IHTPMWVVSDAAREAIDLIERAVEKRQVLTIDYCD-----EAGRGTARDIRPLG 170 Query: 181 LALVQGNWTLVARCGLRQDIRHFRLSRMTELAVLEERFSIPAGFNLSRY 229 L WTLVA C +R D R FR+ R+ + + F G L+ + Sbjct: 171 LWFWGKVWTLVAWCEMRDDFRAFRIDRIASVVIAGRIFKPERGKQLADF 219 >SMc02902 [K] COG2378 Predicted transcriptional regulator Length = 230 Score = 107 bits (266), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 78/222 (35%), Positives = 116/222 (52%), Gaps = 18/222 (8%) Query: 1 MNKTERQLAITLELQRSKMH-RAEDLAAQFETSVRTIYRDIQALSEAGVPIIGAPGQGYS 59 M+++ER L + L+R + LA + S+RT+YRDI +L G I G PG GY Sbjct: 1 MSRSERLLDLMQVLRRYRQPVSGRRLAEETGVSLRTLYRDIASLQARGARIEGEPGIGYV 60 Query: 60 LMEGYFLPPVGFTAEEAVALLMGTDFIEQRLDAEYGSVSKSARRKIEAVLPEPVRAESAR 119 L G+ LPP+ F+ EE AL++G+ ++ +R D + + A KI +VLP ++ Sbjct: 61 LRPGFMLPPMMFSEEEIEALVLGSRWVAKRGDPRLAAAAADALAKIGSVLPADLKE---- 116 Query: 120 VRDTMRLLHAGEPVTGRK---EKDYLGQIRRAILERHRLSFTYLKKMPEADGSRKSSREA 176 +L H+ V RK E L +R++I H+L YL + DG R S R Sbjct: 117 -----KLEHSTLLVGPRKPGGETIDLSLLRKSIRSEHKLELRYL----DNDG-RDSRRTV 166 Query: 177 DPYGLALVQGNWTLVARCGLRQDIRHFRLSRMTELAVLEERF 218 P+ L + L A C LRQD RHFR R+ E A+L++R+ Sbjct: 167 WPFALGFFEEVRVLAAWCELRQDFRHFRTDRIAEAAMLDDRY 208 >lin2535 [K] COG2378 Predicted transcriptional regulator Length = 298 Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 88/319 (27%), Positives = 150/319 (47%), Gaps = 36/319 (11%) Query: 3 KTERQLAITLELQRSKMHRAEDLAAQFETSVRTIYRDIQALSEAGVPIIGAPGQ--GYSL 60 K ER LAI + + K+ A +LA +FE S RTIYRD+ L AG P++ PG+ G+++ Sbjct: 2 KLERILAILVMILERKV-LASELAEKFEVSTRTIYRDMDTLLYAGFPVVALPGKNGGFTM 60 Query: 61 MEGYFLPPVGFTAEEAVALLMGTDFIEQRLDAEYGSVSKSARRKIEAVLPEPVRAESARV 120 ++ Y L F+ EE LL + +E R + ++ R KI + E Sbjct: 61 LDTYKLATFTFSEEEKRILL---EALEARSEFMLNDSQETLREKITLLQTE--------- 108 Query: 121 RDTMRLLHAGEPVTGRKE-----KDYLGQIRRAILERHRLSFTYLKKMPEADGSRKSSRE 175 + T + RK+ K + I++A + +L TY+ DG+ +++RE Sbjct: 109 KPTSNYIFFDSATQHRKQIEAEVKRKIAYIQKAFTMKKQLDITYIA----MDGT-ETNRE 163 Query: 176 ADPYGLALVQGNWTLVARCGLRQDIRHFRLSRMTELAVLEERFSIPAGFNLSRYRPPDDX 235 P L L+ G+W L A C R IRHF+L+R+T S+ S D Sbjct: 164 ISPQKLNLMDGSWYLEAYCHKRAAIRHFKLTRIT---------SLKETSKTSMKIEEDQK 214 Query: 236 XXXXXXXXXXXI-ADKMIETVNYYL-ETTEEREDGLLVTFRIRQLEELLPYILSWGGEAE 293 +++ + ++Y+L E + D + V F+ ++P++L +G + Sbjct: 215 QAEVTEKIVLEFPKNQLGKLLDYFLLEEMQMELDLVRVRFQYDPERNIIPFLLMFGSAVK 274 Query: 294 VLEPVSLRRRVREEAEKMF 312 +LEP SL++ + E EK++ Sbjct: 275 ILEPASLQKEYKAEVEKLY 293 >mll3208 [K] COG2378 Predicted transcriptional regulator Length = 229 Score = 103 bits (256), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 77/222 (34%), Positives = 114/222 (51%), Gaps = 18/222 (8%) Query: 1 MNKTERQLAITLELQRSKMHR----AEDLAAQFETSVRTIYRDIQALSEAGVPIIGAPGQ 56 M+++ER L + L+R HR + LA + S+RT+YRDI L G PI G G Sbjct: 1 MSRSERLLDLIQCLRR---HRRPVSGQALADELGISIRTLYRDIATLQGQGAPIEGEAGL 57 Query: 57 GYSLMEGYFLPPVGFTAEEAVALLMGTDFIEQRLDAEYGSVSKSARRKIEAVLPEPVRAE 116 GY L G+ LPP+ FT EE A+++G+ ++ ++ D + + +A KI AVLP+ +R + Sbjct: 58 GYVLKPGFILPPLMFTDEEIEAIVLGSRWVAKQPDQRLSAAAANALAKIAAVLPDDLRED 117 Query: 117 SARVRDTMRLLHAGEPVTGRKEKDYLGQIRRAILERHRLSFTYLKKMPEADGSRKSSREA 176 D LL G P + D LG +R+AI +L F Y G S R Sbjct: 118 L----DASTLL-VGPPAHAIEGID-LGVVRQAIRNERKLGFLYRDA-----GGAASQRVV 166 Query: 177 DPYGLALVQGNWTLVARCGLRQDIRHFRLSRMTELAVLEERF 218 P+ L +VA C +RQD RHFR R++ L ++ R+ Sbjct: 167 WPFALGFFDKVRVVVAWCEMRQDFRHFRADRISALNAIDARY 208 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,233,505 Number of extensions: 819872 Number of successful extensions: 1631 Number of sequences better than 1.0e-05: 15 Number of HSP's gapped: 1612 Number of HSP's successfully gapped: 15 Length of query: 315 Length of database: 38,378,431 Length adjustment: 106 Effective length of query: 209 Effective length of database: 26,153,027 Effective search space: 5465982643 Effective search space used: 5465982643 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)