BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0359.0009.p (350 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SA2180 [T] COG4585 Signal transduction histidine kinase 317 2e-86 BS_degS [T] COG4585 Signal transduction histidine kinase 123 5e-28 DR1556 [T] COG4585 Signal transduction histidine kinase 109 6e-24 BH3629 [T] COG4585 Signal transduction histidine kinase 109 7e-24 RSc2311_2 [T] COG4585 Signal transduction histidine kinase 108 1e-23 >SA2180 [T] COG4585 Signal transduction histidine kinase Length = 344 Score = 317 bits (812), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 156/342 (45%), Positives = 233/342 (68%), Gaps = 8/342 (2%) Query: 4 LNTLMLKLFENSTEAIFFFDREGRTLAMNPAAAHIVDTDFLKQLEQGNSLA--LCSTCRG 61 L+TL+ K +E+S E I F D G+ +AMN AA D L + + +++A +C C G Sbjct: 9 LDTLLKKYYEHSIEKIVFADDNGKIIAMNDAAK-----DILSEEDNYSAVANAICHRCEG 63 Query: 62 YTSDMELRTCLNCFFHVPDSEDFTSYQVYLETKNKGVIPFAASFHTIDSENGIRVLMLRD 121 YT+ ++++C +CF + T++QV+++TK++ V+PF A++ ID + GI L++ Sbjct: 64 YTNAYDVQSCKDCFLESMQVQ-ATNFQVFMKTKDQKVMPFTATYQLIDQDRGIHAFTLQN 122 Query: 122 LTRQFKTQEKFYQNKMMKHVIEAQENERKRISRELHDSVAQELMSAVVDLRVLKYMTGDE 181 ++ Q + QEK +Q +MM+ I AQENERKRISRELHDSV QE+++ V LR+LKY Sbjct: 123 VSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDSVIQEMLNVDVQLRLLKYQEDTT 182 Query: 182 QLLKKVKQTEVSMTRLLSDIRNLSVELRPAALDDFGLEAAFRSHFKRMEQIYGLMIEFES 241 +LL+ + E + +L+ DIRN+SVELRPA+LDD GLEAAF+S+FK+ E+ YG+ I + S Sbjct: 183 KLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLGLEAAFKSYFKQFEENYGIKIIYTS 242 Query: 242 DLSEKRYGSEIETVVYRVCQEALLNALKYAQVDLVHVKLTERDRLLKLTIEDEGVGFNLG 301 ++ R+ S+IETVVYRV QEA+LNALKYA V+ ++V + + R L + D G GF+ Sbjct: 243 NIKNTRFDSDIETVVYRVVQEAILNALKYADVNEINVGIRQTGRHLVAEVIDAGNGFDPS 302 Query: 302 DEPDGTGLGLYGMQERAELVGGIFSVESGIGLGTRIIIQVPV 343 +P G+GLGLYGM ERAELV G ++E+ IG GT + + +P+ Sbjct: 303 SKPKGSGLGLYGMNERAELVSGSVNIETKIGEGTNVTLNIPI 344 >BS_degS [T] COG4585 Signal transduction histidine kinase Length = 385 Score = 123 bits (308), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 74/212 (34%), Positives = 125/212 (58%), Gaps = 8/212 (3%) Query: 141 VIEAQENERKRISRELHDSVAQELMSAVVDLRVLKYM---TGDEQLLKKVKQTEVSMTRL 197 +IEAQE ERKR+SRE+HD AQ L + ++ +++ + G E +++K ++ Sbjct: 173 IIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNA 232 Query: 198 LSDIRNLSVELRPAALDDFGLEAAFRSHFKRMEQIYG-LMIEFE--SDLSEKRYGSEIET 254 L ++R + +LRP ALDD GL R + E+ G + I F+ + ++R + E Sbjct: 233 LYEVRRIIYDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEV 292 Query: 255 VVYRVCQEALLNALKYAQVDLVHVKLTERDRLLKLTIEDEGVGFNLGD--EPDGTGLGLY 312 ++R+ QEA+ NALK+++ + + VK+ + L I+D G GF+L + E GL Sbjct: 293 ALFRLAQEAVSNALKHSESEEITVKVEITKDFVILMIKDNGKGFDLKEAKEKKNKSFGLL 352 Query: 313 GMQERAELVGGIFSVESGIGLGTRIIIQVPVA 344 GM+ER +L+ G +++S IGLGT I+I+VP++ Sbjct: 353 GMKERVDLLEGTMTIDSKIGLGTFIMIKVPLS 384 >DR1556 [T] COG4585 Signal transduction histidine kinase Length = 569 Score = 109 bits (273), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 74/211 (35%), Positives = 112/211 (53%), Gaps = 11/211 (5%) Query: 142 IEAQENERKRISRELHDSVAQELMSAVVDLRVLKYMTGDEQLLKKVKQTEVSM---TRL- 197 + A E ER R++RELHDSVAQ L + + + + +T+ S+ RL Sbjct: 355 VRAGEEERARLARELHDSVAQALYGITLGAKTARATLDRDPSEAGRNRTQASLDYTIRLA 414 Query: 198 ---LSDIRNLSVELRPAALDDFGLEAAFRSHFKRMEQIYGLMIEFESDLS-EKRYGSEIE 253 +S+++ L LRP AL++ GL AA H +E +GL + +DL E R + + Sbjct: 415 EGGVSEMKALLFSLRPDALEEGGLVAALTQHAHALEARHGLTVH--ADLGHEPRLTPDAQ 472 Query: 254 TVVYRVCQEALLNALKYAQVDLVHVKLTERDRLLKLTIEDEGVGFNLGDEPDGTGLGLYG 313 YRV QEAL N +K+A+ V + L E + LT+ D+G GF+ + GT LG Sbjct: 473 AAAYRVAQEALHNVVKHARAAQVWLSLHEASGTVTLTVRDDGRGFDPQAQGRGT-LGQRS 531 Query: 314 MQERAELVGGIFSVESGIGLGTRIIIQVPVA 344 M+ERA GG +V+S +G GT + + +P A Sbjct: 532 MRERAAGAGGTLTVDSELGAGTTVTLTLPAA 562 >BH3629 [T] COG4585 Signal transduction histidine kinase Length = 377 Score = 109 bits (272), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 59/187 (31%), Positives = 111/187 (59%), Gaps = 4/187 (2%) Query: 140 HVIEAQENERKRISRELHDSVAQELMSAVVDLRVLKYMTGD---EQLLKKVKQTEVSMTR 196 +I+AQE ER+++SRE+HD AQ + + ++ +++ + D ++ LK+++ + Sbjct: 168 QIIQAQEEERRKLSREIHDGPAQMMANVLLRSELVERIYHDKGIDEALKEIRDLRKMVKS 227 Query: 197 LLSDIRNLSVELRPAALDDFGLEAAFRSHFKRMEQIYGLMIEFESDLSEKRYGSEIETVV 256 L+++R + +LRP ALDD GL + + K E+ G+ ++F+ +R+ +E + Sbjct: 228 SLAEVRRIIYDLRPMALDDLGLIPTLKKYVKTFEEHTGIFVDFKHIGKGERFPEHVEIAL 287 Query: 257 YRVCQEALLNALKYAQVDLVHVKLTERDRLLKLTIEDEGVGFNLGDEPDGTGLGLYGMQE 316 +R+ QEAL N K+A+ VHVK+ E+ + I+D G GF+ ++ +G+ GL GM+E Sbjct: 288 FRLVQEALQNTRKHAKASHVHVKIEEQKTKFTVVIKDNGKGFDQTEKKEGS-FGLVGMKE 346 Query: 317 RAELVGG 323 R ++ G Sbjct: 347 RVNMLKG 353 >RSc2311_2 [T] COG4585 Signal transduction histidine kinase Length = 207 Score = 108 bits (270), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 67/199 (33%), Positives = 108/199 (54%), Gaps = 8/199 (4%) Query: 145 QENERKRISRELHDSVAQELMSAVVDLRVLKYMTGDEQLLKKVKQTEVSMTRL---LSDI 201 QE ERKRIS ELHD + Q L + + + + + ++ R+ + D+ Sbjct: 1 QERERKRISAELHDGLGQALTLVKLTVEDALIHIHRNNITEAAELLNTAVLRIRESIGDL 60 Query: 202 RNLSVELRPAALDDFGLEAAFRSHFKRMEQIYG-LMIEFESDLSEKRYGSEIETVVYRVC 260 R + ELRPA LD GL A+ + KR+EQ G L + F+S + ++ ++ ++R+ Sbjct: 61 RRICSELRPALLDRLGLAASLDALCKRVEQEAGHLAVRFDSGVEDEEVPDNLKADIFRIT 120 Query: 261 QEALLNALKYAQVDLVHVKLTERDRLLKLTIEDEGVGFN----LGDEPDGTGLGLYGMQE 316 QEA+ NA+++ + + L + + LTI+D G+GF+ D +GLGL GMQ+ Sbjct: 121 QEAMNNAIRHGAATEIRLSLRRIESGILLTIQDNGIGFDTQPLFADPVSQSGLGLIGMQQ 180 Query: 317 RAELVGGIFSVESGIGLGT 335 R EL GG F ++S +G GT Sbjct: 181 RVELNGGSFFIQSSVGDGT 199 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.136 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,836,737 Number of extensions: 886825 Number of successful extensions: 2225 Number of sequences better than 1.0e-05: 60 Number of HSP's gapped: 2149 Number of HSP's successfully gapped: 60 Length of query: 350 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 243 Effective length of database: 26,037,693 Effective search space: 6327159399 Effective search space used: 6327159399 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)