BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0351.0012.p (243 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2168 [KG] COG1349 Transcriptional regulators of sugar metabolism 150 3e-36 BH1553 [KG] COG1349 Transcriptional regulators of sugar metabolism 128 6e-30 lin2465 [KG] COG1349 Transcriptional regulators of sugar metabolism 112 4e-25 BS_yulB [KG] COG1349 Transcriptional regulators of sugar metabolism 110 2e-24 BS_glcR [KG] COG1349 Transcriptional regulators of sugar metabolism 109 3e-24 >BH2168 [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 259 Score = 150 bits (378), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 90/241 (37%), Positives = 144/241 (59%), Gaps = 3/241 (1%) Query: 2 IMEVLLNQKDVTVNELSDKLQVTGKTIREDLSKLEEQGLIMRVHGGAVLAQSDQFGILPS 61 I+E L K V V++LS +LQV+ KTIR DL LE++GL+ R+HGGAV D+ I P Sbjct: 10 ILEWLEKNKAVKVSDLSRELQVSEKTIRIDLVHLEKKGLLKRIHGGAV-PLDDEGRIFPI 68 Query: 62 KNPLDKYSDEKTEIAQLALAHIAEDDIIALDGGSTTLEIARRLDNIPLTVITNDVYIISE 121 K++ K IA A+ I ++ I +DGGSTTL +A++L P+T+ITNDV I +E Sbjct: 69 NERQSKHNLAKQAIAGEAIKRIQPNETILMDGGSTTLAVAKQLGAFPVTIITNDVRIAAE 128 Query: 122 LVQKDRIRLVVPGGYRV--RNILAGPEAVSYVQKLNIEKAFLSATAVHIEHGLSIYTGDF 179 L+ K++++L+V GG R+ + L PE+ ++++ + + F AT + IEHGL++ Sbjct: 129 LISKEKVQLMVLGGTRIGTSSSLFSPESSELLKRIRVNRLFFGATGISIEHGLTVLNSLH 188 Query: 180 IDFKQALVSTARTVFAVCDHHKFGHTALRTFASLQEVDVLLTDSGLAQETAEQFRNAGVN 239 +++K+ ++ A V + D KF L FA+++EVD ++TD L ++ G Sbjct: 189 VEWKKQVLRCAERVTLLVDSTKFEKVGLIQFATIEEVDEIITDMNLDSAIKKRLETLGRT 248 Query: 240 I 240 I Sbjct: 249 I 249 >BH1553 [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 251 Score = 128 bits (322), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 131/241 (54%), Gaps = 4/241 (1%) Query: 2 IMEVLLNQKDVTVNELSDKLQVTGKTIREDLSKLEEQGLIMRVHGGAVLAQSDQFGILPS 61 I+ ++ + V V+ELS VT +TIR DL KLE + + R HGGAV + D P Sbjct: 10 IIALVTEKGSVRVSELSQLFNVTEETIRRDLEKLESERKLQRSHGGAVSIKEDTEA--PY 67 Query: 62 KNPLDKYSDEKTEIAQLALAHIAEDDIIALDGGSTTLEIARRLDNIPLTVITNDVYIISE 121 + +EK +A A+ ++ +D I LD +T +A+RL ++PLTV+TN + + E Sbjct: 68 FEREIRNVNEKQAVAAQAVTYVTTNDRIILDASTTAWYMAKRLPDVPLTVLTNSMKVAME 127 Query: 122 LVQKDRIRLVVPGGYRVRNILA--GPEAVSYVQKLNIEKAFLSATAVHIEHGLSIYTGDF 179 L ++++I ++ GG +R L+ GP+ ++ ++ KAF+S VH + G+S Sbjct: 128 LAKREKITVITVGGTLLRKSLSFVGPQTNQTLELYHVNKAFISCQGVHAKRGISDSNEMQ 187 Query: 180 IDFKQALVSTARTVFAVCDHHKFGHTALRTFASLQEVDVLLTDSGLAQETAEQFRNAGVN 239 KQ ++ + VF + DH KFG A S++ +D ++TDS ++E F+ ++ Sbjct: 188 ALVKQKMIDISDHVFLLADHTKFGKQAFSRITSMETIDTIITDSKTSEEQISDFQELEMD 247 Query: 240 I 240 + Sbjct: 248 V 248 >lin2465 [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 252 Score = 112 bits (281), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 82/242 (33%), Positives = 128/242 (52%), Gaps = 5/242 (2%) Query: 2 IMEVLLNQKDVTVNELSDKLQVTGKTIREDLSKLEEQGLIMRVHGGAVLAQSDQFGILPS 61 I++ + ++K TV+EL+ +V TIR DL+ LE+ + R HGG ++ + Sbjct: 10 IVQYVKSRKIATVSELAKHFEVHEATIRRDLTSLEKDKKLKRTHGGVMIEEKVVSEPNWK 69 Query: 62 KNPLDKYSDEKTEIAQLALAHIAEDDIIALDGGSTTLEIARRL-DNIPLTVITNDVYIIS 120 K +Y +EK IA LA + + D I LD G+TT IA L D LTVITND+ + S Sbjct: 70 KRSEVRY-EEKQRIATLAATMVKDGDTIILDAGTTTGHIATALKDRSKLTVITNDINVAS 128 Query: 121 ELVQKDRIRLVVPGG--YRVRNILAGPEAVSYVQKLNIEKAFLSATAVHIEHGLSIYTGD 178 +++ +++V GG Y IL G +Q +++ KAF++ A+ I+ GL Y Sbjct: 129 -IMRFSPSKVIVTGGVIYPETFILNGMITSGTLQSIHVHKAFVTTPALDIDKGLMHYDEY 187 Query: 179 FIDFKQALVSTARTVFAVCDHHKFGHTALRTFASLQEVDVLLTDSGLAQETAEQFRNAGV 238 I KQ ++ +A V V DH KFG +L +A+L E+ ++T + EQF G+ Sbjct: 188 LIPAKQQMLHSADEVILVTDHTKFGRISLYKYAALDEISSIITGKEIDPVLKEQFEEKGM 247 Query: 239 NI 240 I Sbjct: 248 QI 249 >BS_yulB [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 258 Score = 110 bits (275), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 78/241 (32%), Positives = 122/241 (50%), Gaps = 3/241 (1%) Query: 2 IMEVLLNQKDVTVNELSDKLQVTGKTIREDLSKLEEQGLIMRVHGGAVLAQSDQFGILPS 61 I+E++ + + V+ELSD VT +TIR DL KLE++ + R HGGAV Q + I S Sbjct: 10 IVEIVNMRSSIRVSELSDIFSVTEETIRRDLEKLEKEHKLSRSHGGAVSIQQKESEIHFS 69 Query: 62 KNPLDKYSDEKTEIAQLALAHIAEDDIIALDGGSTTLEIARRLDNIPLTVITNDVYIISE 121 + + EK IA A ++ D I LD +T +A+ L +I LTVITN + E Sbjct: 70 EREITNVI-EKKAIAHEAAKYVKSGDRIILDASTTAWYMAKILPDIELTVITNSMKAAIE 128 Query: 122 LVQKDRIRLVVPGGYRVRNIL--AGPEAVSYVQKLNIEKAFLSATAVHIEHGLSIYTGDF 179 L K+ I ++ GG + L AGP A ++ ++ K FLS + +G+S Sbjct: 129 LSNKENISVISTGGILLEKSLSFAGPLAERSLETYHVNKTFLSCKGFDVHNGMSDSNEWQ 188 Query: 180 IDFKQALVSTARTVFAVCDHHKFGHTALRTFASLQEVDVLLTDSGLAQETAEQFRNAGVN 239 K+ ++ + + D K+G+ ASLQ+V L+TDSGL + + + V Sbjct: 189 ALLKKRMIERSDQTILMADSSKWGNREFSHIASLQDVSRLITDSGLDPASVKALEDKKVK 248 Query: 240 I 240 + Sbjct: 249 V 249 >BS_glcR [KG] COG1349 Transcriptional regulators of sugar metabolism Length = 258 Score = 109 bits (273), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 71/223 (31%), Positives = 115/223 (51%), Gaps = 4/223 (1%) Query: 2 IMEVLLNQKDVTVNELSDKLQVTGKTIREDLSKLEEQGLIMRVHGGAVLAQSDQFGILPS 61 I++ L +T ++ LQV+ T R DL KLEEQ I+R GGA+L Q I Sbjct: 10 ILDFLKQHNRITTEQICTLLQVSRDTARRDLVKLEEQNAIIRTRGGAILPTVHQ-KIQSY 68 Query: 62 KNPLDKYSDEKTEIAQLALAHIAEDDIIALDGGSTTLEIARRLDNIPLTVITNDVYIISE 121 L S+EK +I +LA + I + D + LD +T A+ L+ + TVITN + + Sbjct: 69 SGRLKTVSEEKNKIGRLAASLIHDGDRVILDASTTVQACAKHLNAVDCTVITNSINLADV 128 Query: 122 LVQKDRIRLVVPGGY--RVRNILAGPEAVSYVQKLNIEKAFLSATAVHIEHGLSIYTGDF 179 L K+ I + + GG + L G + + +++KA + + EHG++I + Sbjct: 129 LSDKEGIEIYLLGGKLEKEHRFLYGSSVIEKLSSYHVDKALIGVVGIS-EHGITIAHEED 187 Query: 180 IDFKQALVSTARTVFAVCDHHKFGHTALRTFASLQEVDVLLTD 222 K+ ++ A+ V A+ DH K G T+ +A L E+D+L+TD Sbjct: 188 GMVKRKMIQQAKQVIALADHSKLGSTSFYQYAELNEIDLLITD 230 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 16,622,122 Number of extensions: 687086 Number of successful extensions: 2410 Number of sequences better than 1.0e-05: 124 Number of HSP's gapped: 2184 Number of HSP's successfully gapped: 124 Length of query: 243 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 140 Effective length of database: 26,499,029 Effective search space: 3709864060 Effective search space used: 3709864060 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)