BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0351.0006.p
         (207 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BH0986 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...   204   5e-53
CAC0446 [LR] COG0494 NTP pyrophosphohydrolases including oxidati...   137   2e-32

>BH0986 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score =  204 bits (520), Expect = 5e-53,   Method: Compositional matrix adjust.
 Identities = 9/203 (4%), Positives = 28/203 (13%)

Query: 1   MNEELLATFDEQGNRTGAAPRDEVHRLGLWHETFHCWFVRRDAGGLMIYLQLRSLHKRDY 60
           M          +                    T     + R  G    ++   +   +  
Sbjct: 1   MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60

Query: 61  AGLLDITAAGHLLADETVVDGVCEVQEELGIAVDFDQLKPLGVIPYQMDTAGFIDRERAH 120
             + +         +   +         L I         +       D    +   +  
Sbjct: 61  REMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKEL 120

Query: 121 VFVYENHYALSEFTPQQEEVAGIVQARFADFRSFITGGSSKLHVEGFRVEGDGERIVLDE 180
                    +                +     +    G             D      + 
Sbjct: 121 TEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNV 180

Query: 181 QVEFSQLVPHEREYYMRVIEGIE 203
                 ++               
Sbjct: 181 LDFDDLILLPTLLLQANEEVRKR 203


>CAC0446 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 206

 Score =  137 bits (344), Expect = 2e-32,   Method: Compositional matrix adjust.
 Identities = 69/202 (34%), Positives = 106/202 (52%)

Query: 1   MNEELLATFDEQGNRTGAAPRDEVHRLGLWHETFHCWFVRRDAGGLMIYLQLRSLHKRDY 60
           M EE L  FDE+    G   R EVH  G WH TFHCW V+R+     +  Q R   K   
Sbjct: 1   MEEEFLDIFDEEERLIGRKSRKEVHEKGYWHSTFHCWVVKREGKKTFLIFQKRHPLKDTA 60

Query: 61  AGLLDITAAGHLLADETVVDGVCEVQEELGIAVDFDQLKPLGVIPYQMDTAGFIDRERAH 120
             + D+++AGH+ + E++ DGV E++EELGI    ++L  +G+I  +      IDRE  H
Sbjct: 61  PNMFDVSSAGHIKSGESIEDGVRELKEELGIDAKPNELINIGIIKEEFHIGKNIDREFCH 120

Query: 121 VFVYENHYALSEFTPQQEEVAGIVQARFADFRSFITGGSSKLHVEGFRVEGDGERIVLDE 180
           +++Y N   +  +T Q++EV G+V+    +   F+      +  EGF V  +G R  L +
Sbjct: 121 IYIYSNKAEIESYTLQRDEVVGLVKIEIDELARFLDNKIDGVFAEGFIVNQEGRRYKLSK 180

Query: 181 QVEFSQLVPHEREYYMRVIEGI 202
            +     VPH+  YY  V+  +
Sbjct: 181 ILNKDDFVPHKYGYYKIVLRAL 202


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.323    0.141    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 16,031,382
Number of extensions: 658266
Number of successful extensions: 954
Number of sequences better than 1.0e-05: 2
Number of HSP's gapped: 955
Number of HSP's successfully gapped: 2
Length of query: 207
Length of database: 38,378,431
Length adjustment: 102
Effective length of query: 105
Effective length of database: 26,614,363
Effective search space: 2794508115
Effective search space used: 2794508115
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 113 (48.1 bits)