BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0065.p (357 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yqhT [E] COG0006 Xaa-Pro aminopeptidase 390 e-108 lin1391 [E] COG0006 Xaa-Pro aminopeptidase 363 e-100 BH2800 [E] COG0006 Xaa-Pro aminopeptidase 354 1e-97 SA1360 [E] COG0006 Xaa-Pro aminopeptidase 351 9e-97 CAC2095 [E] COG0006 Xaa-Pro aminopeptidase 325 1e-88 >BS_yqhT [E] COG0006 Xaa-Pro aminopeptidase Length = 353 Score = 390 bits (1003), Expect = e-108, Method: Compositional matrix adjust. Identities = 184/352 (52%), Positives = 253/352 (71%), Gaps = 1/352 (0%) Query: 7 RVSKLRKVLQEQGLDAILITSGINRRYLSGFTGSSGYVLVTGDDSYLLTDFRYMTQAAEQ 66 ++ KLR + + G+D +LITS N RY++GFTGS+G +++GD + +TDFRY QA Q Sbjct: 2 KLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKVQ 61 Query: 67 VTGLKVVQHGPKFIETVRELLQGANV-RIGFEQDDVTFSAYSTYXXXXXXXXXXXXSKAV 125 V G ++++HG I+T + ++ + R+GFEQ+ +T+ Y++Y +++V Sbjct: 62 VKGFEIIEHGGSLIQTTADTVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAESV 121 Query: 126 ENLRAFKDEGELAVMQRAADLADATFSHILNVIKPGMTERDVDLEMEFYMRTHGATSSSF 185 E LR K E+ +++ AA +AD F HIL +KPG++E V E+EFYMR+ GA SSSF Sbjct: 122 EKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISEIAVANELEFYMRSQGADSSSF 181 Query: 186 DTIVASGERSAMPHGVASSKVIQNNEFVTFDFGALLDGYCSDVTRTIALGSPDPKLKEIY 245 D IVASG RS++PHGVAS K+I++ + VT DFGA GYCSD+TRT+A+G P +LKEIY Sbjct: 182 DMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEIY 241 Query: 246 DIVLEAQLHTLANIKPGMTGRECDALARDIITRYGYGEHFGHSTGHGLGMEVHENPRLSK 305 +V +AQ +A+IKPGMTG+E DAL RD I GYG++FGHSTGHGLGMEVHE+P LS Sbjct: 242 QVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLSV 301 Query: 306 LADEIMEPGMVVTVEPGIYLPGLGGVRIEDDIVITESGMKLLTHSSKDYLVL 357 + I+EPGMVVTVEPGIY+P GGVRIEDDIVITE+G + +THS K+ ++L Sbjct: 302 RSSAILEPGMVVTVEPGIYIPETGGVRIEDDIVITENGNRTITHSPKELIIL 353 >lin1391 [E] COG0006 Xaa-Pro aminopeptidase Length = 353 Score = 363 bits (932), Expect = e-100, Method: Compositional matrix adjust. Identities = 180/352 (51%), Positives = 246/352 (69%), Gaps = 2/352 (0%) Query: 7 RVSKLRKVLQEQGLDAILITSGINRRYLSGFTGSSGYVLVTGDDSYLLTDFRYMTQAAEQ 66 +++K+++ L ++ ++A+L+TS NRRY+SGFTG+SG L+ + +Y +TDFRY QAA+Q Sbjct: 3 KLTKIQETLGKEKIEAVLVTSEFNRRYVSGFTGTSGVALILPEKAYFVTDFRYTEQAAKQ 62 Query: 67 VTGLKVVQHGPKFIETVRELLQGANVR-IGFEQDDVTFSAYSTYXXXXXXXXXXXXSKAV 125 G ++V+H +TV +LL + + + FE D VT S + + Sbjct: 63 AEGYEIVKHEGPIFDTVEDLLIKNDTKTLHFEADYVTVSEFKQ-MERLFNRQLIPLTGFF 121 Query: 126 ENLRAFKDEGELAVMQRAADLADATFSHILNVIKPGMTERDVDLEMEFYMRTHGATSSSF 185 E +R K EL ++ A D+ADA F+HI+ IKPGM E +V E+EF+MR GATSSSF Sbjct: 122 EEMRKVKTASELKAIRTACDIADAAFAHIIKFIKPGMAEIEVSNELEFFMRRAGATSSSF 181 Query: 186 DTIVASGERSAMPHGVASSKVIQNNEFVTFDFGALLDGYCSDVTRTIALGSPDPKLKEIY 245 DTIVASG RSA+PHGVAS K I+ +FVT D+G DGYCSD+TRTIA+G P KLKEIY Sbjct: 182 DTIVASGVRSALPHGVASDKKIEVGDFVTMDYGCYYDGYCSDMTRTIAVGEPAEKLKEIY 241 Query: 246 DIVLEAQLHTLANIKPGMTGRECDALARDIITRYGYGEHFGHSTGHGLGMEVHENPRLSK 305 I L+AQL + ++KPGMTG E DA+ARD I +GYG+ FGHS GHG+G+E+HE P LS Sbjct: 242 QITLDAQLKVIDSLKPGMTGIEADAIARDYIASFGYGDAFGHSLGHGIGLEIHEGPNLSF 301 Query: 306 LADEIMEPGMVVTVEPGIYLPGLGGVRIEDDIVITESGMKLLTHSSKDYLVL 357 + + +E G VVT EPGIYLPG+GGVRIEDD++ITE+G ++L HS K+ ++L Sbjct: 302 KSPQKLEVGHVVTDEPGIYLPGIGGVRIEDDLLITETGNEILIHSPKELIIL 353 >BH2800 [E] COG0006 Xaa-Pro aminopeptidase Length = 355 Score = 354 bits (909), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 187/352 (53%), Positives = 242/352 (68%), Gaps = 2/352 (0%) Query: 7 RVSKLRKVLQEQGLDAILITSGINRRYLSGFTGSSGYVLVTGDDSYLLTDFRYMTQAAEQ 66 R+ ++R + E D +LI S NRRY++ FTG++G +VTG + +TDFRY+ QA EQ Sbjct: 3 RLERIRAAIHEHDFDGLLIMSPYNRRYVTEFTGTAGAAIVTGGAAIFITDFRYVEQAEEQ 62 Query: 67 VTGLKVVQH-GPKFIETVRELLQGANVRIGFEQDDVTFSAYSTYXXXXXXXXXXXXSKAV 125 G +V+H G F E + + ++GFE+ VTF Y + V Sbjct: 63 ARGFDIVKHTGTIFEEIANQAKKLGIQKLGFEKSHVTFETYE-LLNKLVDSELVPVAGLV 121 Query: 126 ENLRAFKDEGELAVMQRAADLADATFSHILNVIKPGMTERDVDLEMEFYMRTHGATSSSF 185 EN+R KDE EL +MQ AA++ADA F+HI + I+ G+TER+V E+EF+MR GA SSSF Sbjct: 122 ENIRLIKDETELQIMQEAANIADAAFAHITSYIRAGVTEREVANELEFFMRKQGAESSSF 181 Query: 186 DTIVASGERSAMPHGVASSKVIQNNEFVTFDFGALLDGYCSDVTRTIALGSPDPKLKEIY 245 D IVASG RSA+PHGVAS KVI+ E VT DFGA GYCSD+TRT+A+G + +L++IY Sbjct: 182 DIIVASGYRSALPHGVASDKVIEKGELVTLDFGAYYKGYCSDITRTVAVGDINDELRKIY 241 Query: 246 DIVLEAQLHTLANIKPGMTGRECDALARDIITRYGYGEHFGHSTGHGLGMEVHENPRLSK 305 D VLEAQL + IKPG+TG+E DAL RD IT GYGE+FGHSTGHGLG+EVHE P LS Sbjct: 242 DTVLEAQLKGMEGIKPGITGKEADALTRDHITAKGYGEYFGHSTGHGLGLEVHEGPGLSM 301 Query: 306 LADEIMEPGMVVTVEPGIYLPGLGGVRIEDDIVITESGMKLLTHSSKDYLVL 357 + +++PGMVVTVEPGIY+ G+GG RIEDD VITESG + LT S K+ L + Sbjct: 302 KSKAVLKPGMVVTVEPGIYISGVGGTRIEDDTVITESGNRSLTKSPKELLFV 353 >SA1360 [E] COG0006 Xaa-Pro aminopeptidase Length = 353 Score = 351 bits (901), Expect = 9e-97, Method: Compositional matrix adjust. Identities = 166/352 (47%), Positives = 240/352 (68%), Gaps = 3/352 (0%) Query: 7 RVSKLRKVLQEQGLDAILITSGINRRYLSGFTGSSGYVLVTGDDSYLLTDFRYMTQAAEQ 66 R++++ ++L+++ LDAI+I S NRRYLSGFTG+SG ++++ D YL+TDFRY+ QA +Q Sbjct: 3 RITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQATKQ 62 Query: 67 VTGLKVVQHGPKFIETVRELLQGANV-RIGFEQDDVTFSAYSTYXXXXXXXXXXXXSKAV 125 +++ I ++ELL N IGFE V++ Y S V Sbjct: 63 APNYEIINRKSTIIGEIKELLHQENFENIGFEGHHVSYDTY--LELNKSRISLISISNTV 120 Query: 126 ENLRAFKDEGELAVMQRAADLADATFSHILNVIKPGMTERDVDLEMEFYMRTHGATSSSF 185 + +R KD E+A++Q+AA++ D T+ +IL V+K GMTE+++ +E M GA SF Sbjct: 121 DKIRDVKDVDEIALIQKAANIVDETYEYILTVVKAGMTEKELKAILESKMLELGADGPSF 180 Query: 186 DTIVASGERSAMPHGVASSKVIQNNEFVTFDFGALLDGYCSDVTRTIALGSPDPKLKEIY 245 DTIVASG R A+PHGVAS K+I+ + +T DFGA +GYCSD+TRT A+G PDPKLKEIY Sbjct: 181 DTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIY 240 Query: 246 DIVLEAQLHTLANIKPGMTGRECDALARDIITRYGYGEHFGHSTGHGLGMEVHENPRLSK 305 IVLE+Q+ + I+PGMTG E DA++R+ + GYG+ FGHS GHG+G+E+HE P L++ Sbjct: 241 QIVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLAR 300 Query: 306 LADEIMEPGMVVTVEPGIYLPGLGGVRIEDDIVITESGMKLLTHSSKDYLVL 357 + ++ VTVEPG+Y+ GLGG+RIEDDI+ITE+G ++ T +KD +VL Sbjct: 301 TIQDKLQVNNCVTVEPGVYIEGLGGIRIEDDILITENGCQVFTKCTKDLIVL 352 >CAC2095 [E] COG0006 Xaa-Pro aminopeptidase Length = 356 Score = 325 bits (832), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 163/357 (45%), Positives = 237/357 (66%), Gaps = 3/357 (0%) Query: 3 MGNKRVSKLRKVLQEQGLDAILITSGINRRYLSGFTGSSGYVLVTGDDSYLLTDFRYMTQ 62 M ++R+ LRK + +G+D +L+ S NR Y+SGFTG + ++T D + +TD R+ Q Sbjct: 1 MYSERIKNLRKAMVNKGIDGVLLISDPNRNYMSGFTGDESFSIITLDKAIFITDSRFTEQ 60 Query: 63 AAEQVT-GLKVVQHGPKFIETVRELLQGANV-RIGFEQDDVTFSAYSTYXXXXXXXXXXX 120 A +QV +VVQ+ F + +++ N+ ++GFE+D ++ S Y +Y Sbjct: 61 AKQQVNENYEVVQYSGPFSSFLGNMVEKLNISKLGFEEDIISVSIYDSYKKSVKAELVPL 120 Query: 121 XSKAVENLRAFKDEGELAVMQRAADLADATFSHILNVIKPGMTERDVDLEMEFYMRTHGA 180 VE LR KDE E+ +++AA +AD FSH+L IK GMTER+V LE+EF M+ GA Sbjct: 121 GG-MVEELRMIKDENEVDTIKKAAAIADKAFSHMLKFIKKGMTEREVGLELEFTMKKLGA 179 Query: 181 TSSSFDTIVASGERSAMPHGVASSKVIQNNEFVTFDFGALLDGYCSDVTRTIALGSPDPK 240 SF +I+ASGERS +PHG A+ K+++ EF+T DFG + + YCSD+TRTI +G P+ K Sbjct: 180 KDLSFPSIIASGERSCLPHGQATDKILKEGEFLTMDFGCVFNDYCSDMTRTIVIGKPNDK 239 Query: 241 LKEIYDIVLEAQLHTLANIKPGMTGRECDALARDIITRYGYGEHFGHSTGHGLGMEVHEN 300 +KEIYD+VL+A L IK G+TGRE D +ARDII +GYGE+FGH GHG+G ++HE Sbjct: 240 MKEIYDVVLKANKEALKVIKSGVTGREVDKVARDIIASHGYGENFGHGLGHGVGRQIHEG 299 Query: 301 PRLSKLADEIMEPGMVVTVEPGIYLPGLGGVRIEDDIVITESGMKLLTHSSKDYLVL 357 PR+S ++ +++ GM+VT EPGIY+PG GGVRIED IV+ + G L+ S K+ + L Sbjct: 300 PRVSPASETVLKSGMIVTDEPGIYIPGFGGVRIEDLIVVKDDGCVCLSESPKELICL 356 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,976,726 Number of extensions: 984045 Number of successful extensions: 2472 Number of sequences better than 1.0e-05: 118 Number of HSP's gapped: 2256 Number of HSP's successfully gapped: 119 Length of query: 357 Length of database: 38,378,431 Length adjustment: 108 Effective length of query: 249 Effective length of database: 25,922,359 Effective search space: 6454667391 Effective search space used: 6454667391 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)