BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0043.p (258 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH3679 [T] COG4753 Response regulator containing CheY-like recei... 154 1e-37 SP0661 [T] COG4753 Response regulator containing CheY-like recei... 114 1e-25 SPy1556 [T] COG4753 Response regulator containing CheY-like rece... 107 3e-23 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 104 1e-22 SPy1062 [T] COG4753 Response regulator containing CheY-like rece... 100 2e-21 >BH3679 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 257 Score = 154 bits (389), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 140/250 (56%), Gaps = 5/250 (2%) Query: 1 LVDDEAPILGNLRRVL-PWQEMGMEIYGMARSGMEALRIAEEQAPDLVLCDIRMPVMDGL 59 +VDDE L+R L W + + A S EA+ E+ DL++ DIRMP M GL Sbjct: 8 IVDDEPRSRRGLKRTLEAWSPKLLNVQTAA-SAKEAITRLNEETIDLIITDIRMPEMSGL 66 Query: 60 TFVGKLREMGLDSEVLLLSGYQEFDYAREAIRLGVKEYICKPIHYEELGNKVREIGTRIR 119 V L+E +++S Y EF+YA A+ LGV+ Y+ KP+ E+L + + + ++ Sbjct: 67 HLVKALQEQNPKPVCIVISAYSEFEYAHTALELGVRHYLLKPVKKEKL---IEAVESALQ 123 Query: 120 SKQYKDKLYNSIPLFQELTPAEDSAKKTPDQLMNQAAQYISERLSFDLGIEEVAHKIGIS 179 K+ +D+ ++ E A + + + +++A YI L +G+++VA + ++ Sbjct: 124 MKKEQDRFGQVEKVWDEKIDAIEKERLSSSDSIHEALHYIDAHLDQKIGLKDVAKSVHLN 183 Query: 180 SSYFCLLFKNRFAMTFVEYVTLQRMEAAKFMLASSDKSIAAISTGVGYQERRYFTKVFQK 239 SY LFK + MTF EY+T +R++ AK +L S+D+ I+ I+ GYQ +YF K+F++ Sbjct: 184 PSYLSALFKEKTNMTFSEYLTRKRLQHAKHLLVSTDRPISDIAEKCGYQTAKYFIKIFKE 243 Query: 240 QTGMTPKEYR 249 GMTP +YR Sbjct: 244 HEGMTPTQYR 253 >SP0661 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 245 Score = 114 bits (285), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 66/250 (26%), Positives = 134/250 (53%), Gaps = 17/250 (6%) Query: 1 LVDDEAPILGNLRRVLPWQEMGMEIYGMARSGMEALRIAEEQAPDLVLCDIRMPVMDGLT 60 +V+DE + L +++ MEI G A +G +A + ++Q PD++L DI MP ++G+ Sbjct: 7 IVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWELIQKQVPDIILTDINMPHLNGIQ 66 Query: 61 FVGKLREMGLDSEVLLLSGYQEFDYAREAIRLGVKEYICKPIHYEELGNKVREIGTRIRS 120 +RE ++ L+GY +FDYA A++LGV +Y+ KP +++ + +I ++ Sbjct: 67 LASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDDYLLKPFSRQDIEEMLGKIKQKLDK 126 Query: 121 KQYKDKLYNSIPLFQELTPAEDSAKKTPDQLMNQAAQYISERLS-FDLGIEEVAHKIGIS 179 ++ +++L + + ++ AQ I L+ ++ +A +G S Sbjct: 127 EEKEEQLQDLL----------------TNRFEGNMAQKIQSHLADSQFSLKSLASDLGFS 170 Query: 180 SSYFCLLFKNRFAMTFVEYVTLQRMEAAKFMLASSDKSIAAISTGVGYQERRYFTKVFQK 239 +Y L K + F +Y+ +R++ AK +L ++D I I+ VG+++ YFT+ F++ Sbjct: 171 PTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGFEDMNYFTQRFKQ 230 Query: 240 QTGMTPKEYR 249 G+TP++++ Sbjct: 231 IAGVTPRQFK 240 >SPy1556 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 246 Score = 107 bits (266), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 68/250 (27%), Positives = 137/250 (54%), Gaps = 15/250 (6%) Query: 1 LVDDEAPILGNLRRVLPWQEMGMEIYGMARSGMEALRIAEEQAPDLVLCDIRMPVMDGLT 60 +V+DE + +R ++ + + ++ A +G A + +++ D+VL DI MP ++G+ Sbjct: 6 IVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPKLNGIQ 65 Query: 61 FVGKLREMGLDSEVLLLSGYQEFDYAREAIRLGVKEYICKPIHYEELGNKVREIGTRIRS 120 +++ + ++ L+GY +F+YA A++LG +Y+ KP + V ++ ++R Sbjct: 66 LAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKAD----VEDMLGKLRK 121 Query: 121 KQYKDKLYNSIPLFQELTPAEDSAKKTPDQLMNQAAQYISERLS-FDLGIEEVAHKIGIS 179 K K +I QEL + P + ++ A I ERL+ DL ++ +A ++G S Sbjct: 122 KLELSKKTETI---QELV-------EQPQKEVSAIAMAIHERLADSDLTLKSLAQQLGFS 171 Query: 180 SSYFCLLFKNRFAMTFVEYVTLQRMEAAKFMLASSDKSIAAISTGVGYQERRYFTKVFQK 239 +Y +L K M F +Y+ +R++ AK +L +S+ I I+ VG+++ YF++ F++ Sbjct: 172 PNYLSVLIKKELGMPFQDYLVQERLKKAKLLLLTSNLKIYEIAEQVGFEDMNYFSQRFKQ 231 Query: 240 QTGMTPKEYR 249 G+TP +Y+ Sbjct: 232 LVGVTPSQYK 241 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 50/145 (34%), Positives = 86/145 (59%), Gaps = 4/145 (2%) Query: 1 LVDDEAPILGNLRRVLPWQEMGMEIYGMARSGMEALRIAEEQAPDLVLCDIRMPVMDGLT 60 ++DDE ++ L++++ W+ +G E G A +G L I E +P +VL DI MP+M GL Sbjct: 6 IIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPIMYGLD 65 Query: 61 FVGKLREMGLDSEVLLLSGYQEFDYAREAIRLGVKEYICKPIHYEELGNKVREIGTRIRS 120 + LRE G D EV++LSGY EF++AR+A++L + +Y+ KP + + ++ + ++ Sbjct: 66 MIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVINKLEE 125 Query: 121 KQ----YKDKLYNSIPLFQELTPAE 141 KQ Y +L N + ++ L E Sbjct: 126 KQRQQGYLQELTNKVKRYEPLVETE 150 Score = 67.8 bits (164), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 36/98 (36%), Positives = 57/98 (58%) Query: 150 QLMNQAAQYISERLSFDLGIEEVAHKIGISSSYFCLLFKNRFAMTFVEYVTLQRMEAAKF 209 QL+ Q YI + L+ ++ ++++A ++ IS +Y +FK +F YVT RME AK Sbjct: 424 QLIEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKK 483 Query: 210 MLASSDKSIAAISTGVGYQERRYFTKVFQKQTGMTPKE 247 M+ + I +S VGY YFT +F+K TG TP++ Sbjct: 484 MIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRD 521 >SPy1062 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 262 Score = 100 bits (250), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 69/258 (26%), Positives = 118/258 (45%), Gaps = 18/258 (6%) Query: 1 LVDDEAPILGNLRRVLPWQEMGMEIYGMARSGMEALRIAEEQAPDLVLCDIRMPVMDGLT 60 +++DE I LR + ++ + + + G A+ G E + +E PD+VL DI MP+M Sbjct: 6 IIEDEHIIRKWLRYAIDYKALDILVIGEAKDGKEGAVLIKESQPDIVLTDINMPIMTAFD 65 Query: 61 FVGKLREMGLDSEVLLLSGYQEFDYAREAIRLGVKEYICKPIHYEELGNKVREIGTRIR- 119 ++ ++LSGY +F AR AI GV E++ KPI L ++ I +I Sbjct: 66 MFEVTKDQTYAK--IILSGYADFPNARSAIHYGVLEFLTKPIEKAALWECLQTIIAKIEK 123 Query: 120 ---SKQYKDK-LYNSIPLFQELTPAEDSAKKTPDQLMNQAAQYISERLSFDLGIEEVAHK 175 S Q D +Y +P + P +++ +++ + +AH Sbjct: 124 QKGSNQKTDACVYIPLPQMTDQIP----------EVVKDILEWVHAHFQDKISTSRLAHD 173 Query: 176 IGISSSYFCLLFKNRFAMTFVEYVTLQRM-EAAKFMLASSDKSIAAISTGVGYQERRYFT 234 +G S SY K M +Y+ R+ +A + M D + I+ VG + RYF Sbjct: 174 LGYSESYIYQNIKKHLQMPLSDYINQYRINQAIQLMQQEPDLMVYEIAQAVGIYDYRYFD 233 Query: 235 KVFQKQTGMTPKEYRDLH 252 +VF+K G T K +++ H Sbjct: 234 RVFKKYLGQTVKAFKEEH 251 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.137 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,868,873 Number of extensions: 785822 Number of successful extensions: 3195 Number of sequences better than 1.0e-05: 275 Number of HSP's gapped: 3321 Number of HSP's successfully gapped: 282 Length of query: 258 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 154 Effective length of database: 26,383,695 Effective search space: 4063089030 Effective search space used: 4063089030 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 115 (48.9 bits)