BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0350.0021.p (234 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl0291 [T] COG0664 cAMP-binding proteins - catabolite gene acti... 87 3e-17 ML2302 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 80 3e-15 AGl974 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 78 1e-14 DR2362 [T] COG0664 cAMP-binding proteins - catabolite gene activ... 75 1e-13 BMEII0986 [T] COG0664 cAMP-binding proteins - catabolite gene ac... 74 1e-13 >Cgl0291 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 227 Score = 86.7 bits (213), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 50/200 (25%), Positives = 93/200 (46%) Query: 19 NRLLVTMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQAGDMVG 78 N L+ M+ P G+ +F EG+ D+L+ I G+VKL + +G+E +L + DM G Sbjct: 23 NNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARHAPDGRENLLTIMGPSDMFG 82 Query: 79 QADPFFSTKHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRLTQTKFR 138 + F + +A L + H A ++ + R T Sbjct: 83 ELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVADHPAIAEQLLRVLARRLRRTNASLA 142 Query: 139 DLMMYGKPGALCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNRMLSDLR 198 DL+ PG + TL++L N +G + ++ +N +T +++ ++GA+RE+VN+ L+ Sbjct: 143 DLIFTDVPGRVAKTLLQLANRFGTQEAGALRVNHDLTQEEIAQLVGASRETVNKALATFA 202 Query: 199 KKDAVEYENGMIVIKDLSML 218 + + E ++I D L Sbjct: 203 HRGWIRLEGKSVLIVDTEHL 222 >ML2302 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 311 Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 9/188 (4%), Positives = 29/188 (15%) Query: 31 PEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQAGDMVGQADPFFSTKHSF 90 + I G + K + + Sbjct: 32 ITLVLVGLFLSVILNTSKISNGIENNVRIVAYMKLDVHDQETKIQDPKDNKKTINNPDHL 91 Query: 91 TAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRLTQTKFRDLMMYGKPGALC 150 + W ++ KP + Sbjct: 92 KIYDSIKKVPNVKTVEFSSKEAQLKELTKALGNNWNLFKGDANPLYDAYIVEADKPANVK 151 Query: 151 STLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNRMLSDLRKKDAVEYENGMI 210 S ++ G + N + + ++ + ++ Sbjct: 152 SVTSKISKLSGIEKATYGGANTAKLFQIAQGIRTWGTAAAILLIFVAVFLISNTIRITIL 211 Query: 211 VIKDLSML 218 + + Sbjct: 212 SRQREIQI 219 >AGl974 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 82 Score = 77.8 bits (190), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 0/213 (0%), Positives = 0/213 (0%) Query: 13 FSEQNFNRLLVTMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQ 72 + + ++ + + + + + + + + + + Sbjct: 19 AAVDSDEPVVGNSEVKKLEDRVRELERMLGRKTMEVEILREALSKADSKKRISRPILLPK 78 Query: 73 AGDMVGQADPFFSTKHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRL 132 Sbjct: 79 138 Query: 133 TQTKFRDLMMYGKPGALCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNR 192 Sbjct: 139 198 Query: 193 MLSDLRKKDAVEYENGMIVIKDLSMLQDICHCE 225 Sbjct: 199 231 >DR2362 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 297 Score = 74.7 bits (182), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 6/207 (2%), Positives = 34/207 (16%), Gaps = 12/207 (5%) Query: 13 FSEQNFNRLLVTMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQ 72 + + L + ++ + + + + Sbjct: 19 IAPEKEQDLKTIVDDKKIIISVVSEPGFNIRVRKNESNNSHEIVLTVASLEYIWAF---- 74 Query: 73 AGDMVGQADPF------FSTKHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWM 126 + F K + + Sbjct: 75 --SNFFWVFTQEYSKSQKNNDEHFDLTGKNRLKKSDELLKWARKNLQTTGCESWPKKCPK 132 Query: 127 GIHHRLTQTKFRDLMMYGKPGALCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGAT 186 + + + + + + + + S+ Sbjct: 133 PEAYLQGSEDSQVASEIFLCAIAWILHHEISHVVLQHPLVTTAFSTQEEREADSHATKWI 192 Query: 187 RESVNRMLSDLRKKDAVEYENGMIVIK 213 ++ +L+K+ + + Sbjct: 193 LGNLYESAPELKKRALGIATAVLCIQS 219 >BMEII0986 [T] COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Length = 231 Score = 74.3 bits (181), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 47/208 (22%), Positives = 96/208 (46%) Query: 18 FNRLLVTMKERMVPEGSHLFWEGDYSDKLFYIKRGRVKLTKSTDEGKELILYMYQAGDMV 77 +RL+ R VP+G +F +GD + + + GR+K+ + T +G+++I+ M GD+ Sbjct: 23 LDRLVSYATSRRVPQGESIFEQGDEASCFYLLLHGRLKVNQVTPDGQQIIVRMVHPGDLF 82 Query: 78 GQADPFFSTKHSFTAXXXXXXXXXXXXQKDLEILICQHCDFAIDFMKWMGIHHRLTQTKF 137 G A + TA + + + Q+ A++ ++ +G T+ Sbjct: 83 GFARALQRNDYPGTATAVMESIVLAWPTELWDYFVEQNPGLAMNAIQTIGKRLEEAHTRI 142 Query: 138 RDLMMYGKPGALCSTLIRLGNTYGEKSGDSILINKKITHTDLSNMIGATRESVNRMLSDL 197 R++ + ++RL G+K I I+ I+ D++ M G T +V+R+LS+ Sbjct: 143 REMSTEEVERRVAHAVLRLSRQAGKKEETGIRIDFPISRQDIAEMTGTTLHTVSRILSNW 202 Query: 198 RKKDAVEYENGMIVIKDLSMLQDICHCE 225 K V+ +++ D + L+ + E Sbjct: 203 ETKGLVQGGRQKLLVLDSAGLRRLAEGE 230 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.138 0.420 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 15,393,340 Number of extensions: 552926 Number of successful extensions: 1036 Number of sequences better than 1.0e-05: 23 Number of HSP's gapped: 1027 Number of HSP's successfully gapped: 23 Length of query: 234 Length of database: 38,378,431 Length adjustment: 103 Effective length of query: 131 Effective length of database: 26,499,029 Effective search space: 3471372799 Effective search space used: 3471372799 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 114 (48.5 bits)