BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0349.0010.p (805 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2139 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, t... 777 0.0 BS_grlA [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 776 0.0 lin1326 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, ... 733 0.0 SA1189 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, t... 710 0.0 L0291 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, to... 687 0.0 >BH2139 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Length = 816 Score = 777 bits (2006), Expect = 0.0, Method: Compositional matrix adjust. Identities = 393/807 (48%), Positives = 571/807 (70%), Gaps = 19/807 (2%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LEEV+GDRFGRYSKYIIQ+RA+PD RDGLKPVQRRILYAMY GNT DKP+RKSAKTVG+ Sbjct: 12 LEEVIGDRFGRYSKYIIQERALPDARDGLKPVQRRILYAMYRDGNTADKPFRKSAKTVGN 71 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 V+GNYHPHGDSS+Y+ M+RM+Q WK+ ++L+D HGN GS+D DP AAMRYTEARLS IA Sbjct: 72 VIGNYHPHGDSSVYDAMIRMSQEWKVRNILVDMHGNNGSIDGDPPAAMRYTEARLSKIAA 131 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 E++RDI+K TV + NFD++ +EPVV+P+++PNLLVNG++GIS+G+AT+IPPH+L EVID Sbjct: 132 ELLRDIDKETVDYIPNFDDSEQEPVVLPAKFPNLLVNGSTGISSGYATDIPPHHLGEVID 191 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 I M+ P++ L+++M IKGPDFP AY TGKG++ +R K EIE+LR Sbjct: 192 GVIMQMENPNVTLDELMQVIKGPDFPTGGIVQGIEGIRQAYSTGKGKVVVRGKAEIEDLR 251 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 GGKQQIVITE+P+++VK+ LV M+ IR +KK++GIAEVRD++ R GLRIVVELKK+ADA Sbjct: 252 GGKQQIVITEIPYEVVKANLVKKMDEIRFDKKVDGIAEVRDDTDRTGLRIVVELKKDADA 311 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 GIL YL K TDLQ+TYNFNMVAI NK+P+ +GLK++++AYI HQ++V+ R +DL+KA Sbjct: 312 NGILQYLFKNTDLQITYNFNMVAIHNKTPRLMGLKSLIQAYIDHQKDVIIRRATYDLQKA 371 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 +DR H+++GL+KA++ILD+VI I+ASK++++A++NL+ F F+E QA++I+TLQLYRLT Sbjct: 372 KDRQHIVQGLMKAISILDDVIQTIRASKDKKNAKDNLIAQFDFTEAQAEAIVTLQLYRLT 431 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +L++E E+ RI L+ IL S+KKLI V++KEL+ I+ ++ +RR++I+ Sbjct: 432 NTDITTLEEEAAELERRIHELEAILASEKKLIGVVKKELLAIKKQFTDERRTIIKKEIEE 491 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 +EDV+V ++ +GY+KRT + S+ S GE G+KEGD+++ ++NT+D Sbjct: 492 IKITMDVLVASEDVMVTVTKEGYVKRTSLRSYAASNGE--LPGMKEGDYLLGRYEMNTQD 549 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPGASLV 604 +LL+FT+KG Y LPVHQ+P+ +WK+ G + N++ + K D I + L V + SL+ Sbjct: 550 TLLLFTKKGNYLYLPVHQLPDIRWKDNGQHVANLVTVDKDDDILTTLAVKEFSEE-ESLL 608 Query: 605 FVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIRF 663 F+TR+G KR++L Y R S + A K+ + DEV++V +SG++E+ + T G + F Sbjct: 609 FITRQGMAKRSQLSLYKAQRFSKPLMALKLKDDDEVVSVMRTSGNEEVFIATSFGYGLWF 668 Query: 664 RENEVNPMGRVASGVRGIQLREGDEVV--SCFWVNEDEGEILAVTEIGYAKRTLLLDYPA 721 ENE++ +G+ A+GV+GI L+ D VV + F +N D E L VT G KR + ++ Sbjct: 669 SENEISQVGQRAAGVKGINLKNDDAVVDATTFTLN-DRVEFLVVTHRGGVKRISITEFDK 727 Query: 722 QSRGGKGMPTF-EFKEGKRVRPNGSRI---SGAFYCREPLELVAITREGATHSFSSESAP 777 +R +G+ E K+ RI S F+ + T +G + + S Sbjct: 728 STRAKRGLVMLRELKKNPHHIVACKRISDGSDTFFIK--------TEDGTIVTVAPSSFR 779 Query: 778 LSERRSIGKQLVSVEKKDEIISLFPAI 804 S+R S G ++ +K + +++ + Sbjct: 780 RSDRYSNGSFVLDQDKTGVVTNVWKEV 806 >BS_grlA [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Length = 806 Score = 776 bits (2005), Expect = 0.0, Method: Compositional matrix adjust. Identities = 392/798 (49%), Positives = 552/798 (69%), Gaps = 10/798 (1%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LEEV+GDRFGRYSKYIIQDRA+PD RDGLKPVQRRILYAM+ GNT DK +RK+AKTVG+ Sbjct: 12 LEEVIGDRFGRYSKYIIQDRALPDARDGLKPVQRRILYAMHTDGNTFDKNFRKAAKTVGN 71 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 V+GNYHPHGDSS+YE MVRM+Q WK+ +VLI+ HGN GS+D DP AAMRYTEARLSPIA Sbjct: 72 VIGNYHPHGDSSVYEAMVRMSQDWKVRNVLIEMHGNNGSIDGDPPAAMRYTEARLSPIAS 131 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 E++RDI+K TV F NFD+T+KEPVV+P+ +PNLLVNG++GISAG+AT+IPPH+L EVID Sbjct: 132 ELLRDIDKNTVEFVPNFDDTSKEPVVLPAMFPNLLVNGSTGISAGYATDIPPHHLGEVID 191 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 A I +Q P +++++M IKGPDFP AY TGKG+I +R K EIE +R Sbjct: 192 AVIKRIQMPSCSVDELMELIKGPDFPTGGIIQGVDGIRKAYETGKGKIIIRGKAEIETIR 251 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 GG++QIVITE+PF++ K+ LV M+ R++KK+EGI+EVRDE+ R GLR+V+ELKKEADA Sbjct: 252 GGREQIVITEIPFEVNKANLVKKMDEFRIDKKVEGISEVRDETDRTGLRVVIELKKEADA 311 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 +GIL +L K TDLQ+TYNFNMVAI N+ P + L +IL+AYI HQ+EVVT+R+ ++L+KA Sbjct: 312 KGILNFLYKNTDLQITYNFNMVAIHNRRPMLMSLPSILDAYIGHQKEVVTNRSVYELQKA 371 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 +DR H++EGL+KAL+ILDEVIA I++S +++DA+NNL+ + F+E QA++I++LQLYRLT Sbjct: 372 KDRHHIVEGLMKALSILDEVIATIRSSSDKRDAKNNLIAKYEFTEPQAEAIVSLQLYRLT 431 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +L++E +E+ +I L+ IL +DKKL+ VI L ++ KY RRS+I+ Sbjct: 432 NTDITALKEEAEELGKKIEELESILSNDKKLLKVITNSLKALKKKYADTRRSVIEEKIEE 491 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 +EDV V ++ DGY+KRT SF S G+ G+K+ D ++ ++NT D Sbjct: 492 IKINLEVMVASEDVYVTVTKDGYLKRTSQRSFAASNGQ--DFGMKDTDRMLHQFEMNTTD 549 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPGASLV 604 LL+FT KG Y PVHQ+P+ +WK+ G N+I + + + I +P+ DP A L+ Sbjct: 550 VLLLFTNKGSYIYCPVHQLPDIRWKDMGQHFSNLITIDRDETIVKAIPIKEF-DPSAYLL 608 Query: 605 FVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIRF 663 F T+ G VK+TEL Y R S A+ A + DE++ V +++G+ +I + T G + F Sbjct: 609 FFTKNGMVKKTELTHYKAQRYSKALVALNLKGEDELIDVHVTNGESQIFMATHLGYGLWF 668 Query: 664 RENEVNPMGRVASGVRGIQLREGDEVVSCFWVNEDEGEILAVTEIGYAKRTLLLDYPAQS 723 E+EVN +G A+GV+GI L+E D VVS + + + I+ T+ G KR L ++ S Sbjct: 669 GEDEVNVVGARAAGVKGINLKEDDFVVSGEILQQSDS-IVLFTQRGAVKRMSLSEFEKTS 727 Query: 724 RGGKGMPTFEFKEGKRVRPNGSRISGAFYCREPLELVAITREGATHSFSSESAPLSERRS 783 R +G+ + ++ N R+ F C L+A T +G ++ ++R S Sbjct: 728 RAKRGVVML-----RELKKNPHRVVALFACGLEQRLMAETEKGDRKELQTKELRTNDRYS 782 Query: 784 IGKQLVSVEKKDEIISLF 801 G E+ ++ +++ Sbjct: 783 NGSFFFDEEESGKVTAVW 800 >lin1326 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Length = 301 Score = 733 bits (1893), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/728 (0%), Positives = 0/728 (0%), Gaps = 7/728 (0%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 + ++ + R R + + Sbjct: 13 IVGRPNVGKSTLLNKLLGQKISITSRKAQTTRHRIVGIHTEGAYQAIYVDTPGLHMEEKR 72 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 + SS + + + D + + A + + Sbjct: 73 AINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNKLREGKAPVILAVNKVDNVQEK 132 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 + + + D + + A R Sbjct: 133 ADLLPHLQFLASQMNFLDIVPISAETGLNVDTIAAIVRKHLPEATHHFPEDYITDRSQRF 192 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 ++++ + R + Sbjct: 193 MASEIIREKLMRFLGAELPYSVTVEIERFVSNERGGYDINGLILVEREGQKKMVIGNKGA 252 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 Sbjct: 253 312 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 Sbjct: 313 372 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 Sbjct: 373 432 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 Sbjct: 433 492 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 Sbjct: 493 -- 550 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIG-LAKGDGIASILPVGNMDDPGASL 603 Sbjct: 551 - 609 Query: 604 VFVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIR 662 Sbjct: 610 - 668 Query: 663 FRENEVNPMGRVASGVRGIQLREGDEVV-SCFWVNEDEGEILAVTEIGYAKRTLLLDYPA 721 Sbjct: 669 728 Query: 722 QSRGGKGM 729 Sbjct: 729 736 >SA1189 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Length = 800 Score = 710 bits (1832), Expect = 0.0, Method: Compositional matrix adjust. Identities = 361/799 (45%), Positives = 540/799 (67%), Gaps = 12/799 (1%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LE+V+GDRFGRYSKYIIQ+RA+PDVRDGLKPVQRRILYAMY SGNT DK +RKSAKTVGD Sbjct: 10 LEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRRILYAMYSSGNTHDKNFRKSAKTVGD 69 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 V+G YHPHGDSS+YE MVR++Q WK+ HVLI+ HGN GS+D+DP AAMRYTEA+LS +A Sbjct: 70 VIGQYHPHGDSSVYEAMVRLSQDWKLRHVLIEMHGNNGSIDNDPPAAMRYTEAKLSLLAE 129 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 E++RDI K TV F N+D+T EP+V+PSR+PNLLVNG++GISAG+AT+IPPHNL EVI Sbjct: 130 ELLRDINKETVSFIPNYDDTTLEPMVLPSRFPNLLVNGSTGISAGYATDIPPHNLAEVIQ 189 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 A + + PDI + +M +IKGPDFP AY +GKGRI +RSK E E LR Sbjct: 190 ATLKYIDNPDITVNQLMKYIKGPDFPTGGIIQGIDGIKKAYESGKGRIIVRSKVEEETLR 249 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 G++Q++ITE+P+++ KS LV ++ +R +KK++GI EVRDE+ R GLRI +ELKK+ ++ Sbjct: 250 NGRKQLIITEIPYEVNKSSLVKRIDELRADKKVDGIVEVRDETDRTGLRIAIELKKDVNS 309 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 + I YL K +DLQ++YNFNMVAI + P+ +G++ I+++Y+ HQ EVV +RT+F+L+ A Sbjct: 310 ESIKNYLYKNSDLQISYNFNMVAISDGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNA 369 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 E R H++EGL+KAL+ILD+VI I++SKN++DA+ NL+ +F F+E QA++I+ LQLYRLT Sbjct: 370 EKRMHIVEGLIKALSILDKVIELIRSSKNKRDAKENLIEVFEFTEEQAEAIVMLQLYRLT 429 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +L+ E E+ A I L+ IL++ L+ VI++EL EI+ K+ +R SLI+ Sbjct: 430 NTDIVALEGEHKELEALIKQLRHILDNHDALLNVIKEELNEIKKKFKSERLSLIEAEIEE 489 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 +E+V+++++ GYIKRT + SF SG E G+K+GD +++ ++NT+D Sbjct: 490 IKIDKEVMVPSEEVILSMTRHGYIKRTSIRSFNASGVE--DIGLKDGDSLLKHQEVNTQD 547 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDDPGASLV 604 ++LVFT KG+Y +PVH++ + +WKE G + ++ + + + + ++ + + A V Sbjct: 548 TVLVFTNKGRYLFIPVHKLADIRWKELGQHVSQIVPIEEDEVVINVFNEKDF-NTDAFYV 606 Query: 605 FVTRKGQVKRTELKEYSTSR-SGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMSIRF 663 F T+ G +K++ + + T+R + + A KV E D++++V D+ I ++T +GMS+ + Sbjct: 607 FATQNGMIKKSTVPLFKTTRFNKPLIATKVKENDDLISVMRFEKDQLITVITNKGMSLTY 666 Query: 664 RENEVNPMGRVASGVRGIQLREGDEVVSCFWVNEDEGEILAVTEIGYAKRTLLLDYPAQS 723 +E++ G A+GV+ I L+ D VV V+E++ IL T+ G KR Sbjct: 667 NTSELSDTGLRAAGVKSINLKAEDFVVMTEGVSENDT-ILMATQRGSLKRISFKILQVAK 725 Query: 724 RGGKGMPTFEFKEGKRVRPNGSRISGAFYCR-EPLELVAITREGATHSFSSESAPLSERR 782 R +G+ K ++ N RI A E + ++ H ++ SE+ Sbjct: 726 RAQRGITLL-----KELKKNPHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHK-SEQY 779 Query: 783 SIGKQLVSVEKKDEIISLF 801 + G +V + E+I ++ Sbjct: 780 TNGSFIVDTDDFGEVIDMY 798 >L0291 [L] COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit Length = 824 Score = 687 bits (1772), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/780 (45%), Positives = 509/780 (65%), Gaps = 17/780 (2%) Query: 5 LEEVVGDRFGRYSKYIIQDRAIPDVRDGLKPVQRRILYAMYDSGNTPDKPYRKSAKTVGD 64 LE+++GDRFGRYSKYIIQ+RA+PD+RDGLKPVQRRILY+M GNT DK YRKSAK+VG+ Sbjct: 9 LEDIMGDRFGRYSKYIIQERALPDIRDGLKPVQRRILYSMNKDGNTFDKSYRKSAKSVGN 68 Query: 65 VMGNYHPHGDSSIYEGMVRMAQPWKMGHVLIDGHGNWGSMDDDPAAAMRYTEARLSPIAM 124 VMGN+HPHGDSSIYE M+RM+Q WKMG LI+ HGN GSMD DP AAMRYTEARLS I+ Sbjct: 69 VMGNFHPHGDSSIYEAMIRMSQDWKMGEPLIEMHGNNGSMDGDPPAAMRYTEARLSEISG 128 Query: 125 EMMRDIEKRTVLFKDNFDNTAKEPVVVPSRYPNLLVNGTSGISAGFATEIPPHNLREVID 184 ++ DIEK TV NFD+T KEP V+P+ +PNLLVNG++GISAG+AT+IPPHNL EVID Sbjct: 129 YLLADIEKDTVSQAWNFDDTEKEPTVLPAAFPNLLVNGSTGISAGYATDIPPHNLGEVID 188 Query: 185 ACIAVMQKPDIALEDIMTFIKGPDFPXXXXXXXXXXXXDAYRTGKGRIYLRSKTEIENLR 244 A I ++ P +E IM F+ GPDFP AY GKGRI +RSK +IE ++ Sbjct: 189 ATIHMIDHPKADVEKIMEFLPGPDFPTGGIIQGKGEIRKAYEKGKGRIVVRSKVDIEPMK 248 Query: 245 GGKQQIVITEVPFQIVKSRLVTSMENIRLEKKIEGIAEVRDESGRDGLRIVVELKKEADA 304 GG++Q+++TE+PF++ K+ LV ++++R+ K+ GIAEVRDES R+GLRI +ELKKEAD+ Sbjct: 249 GGREQLIVTEIPFELNKANLVKKIDDVRVNAKVPGIAEVRDESDREGLRIAIELKKEADS 308 Query: 305 QGILAYLLKKTDLQVTYNFNMVAIVNKSPQQLGLKAILEAYIAHQREVVTHRTQFDLEKA 364 Q +L YL K TDLQV YNFNMVAI N +P Q G+ +L +Y+ H+ +V+ R+QFDL KA Sbjct: 309 QLVLNYLFKNTDLQVNYNFNMVAIDNMTPVQTGVLQMLRSYVKHREDVIVKRSQFDLNKA 368 Query: 365 EDRAHVLEGLVKALNILDEVIAAIKASKNRQDAQNNLVWMFGFSERQADSILTLQLYRLT 424 E R H++EGL++ ++ILDEV+A I+AS+N+ DA+ N+ FGF+E QA++I+TLQLYRLT Sbjct: 369 EKRLHIVEGLIRMVSILDEVVATIRASENKADAKENIKVSFGFTEEQAEAIVTLQLYRLT 428 Query: 425 NLEIHSLQKELDEMNARIAVLKGILESDKKLIAVIRKELIEIRDKYGIDRRSLIQGXXXX 484 N +I +LQ E E+ +I LK I+ ++ L ++++EL E++ K+ RRS +Q Sbjct: 429 NTDIVTLQNEQAELEQKILELKAIINDERTLFNLMKRELREVKKKFAKPRRSELQDEVQT 488 Query: 485 XXXXXXXXXNAEDVLVALSADGYIKRTGMLSFTRSGGERNASGVKEGDHIVRLMDLNTRD 544 AED +V+++ GYIKRT SF S E G ++ D ++ + T Sbjct: 489 IEIEASELIVAEDTVVSVTRSGYIKRTSPRSFASSALEE--IGKRDDDELLYYANAKTTQ 546 Query: 545 SLLVFTRKGQYFLLPVHQIPEFKWKEPGTAIVNVIGLAKGDGIASILPVGNMDD-PGASL 603 LL+FT G P+H++ + +WK+ G + + D ++ V +D+ G +L Sbjct: 547 HLLLFTNLGNVIYRPIHELSDIRWKDIGEHLSQSLSNFSAD--EKVIFVQIVDEFAGENL 604 Query: 604 VFVTRKGQVKRTELKEYS---TSRSGAVAACKVAEGDEVLTVALSSGDKEIVLVTREGMS 660 + VTR GQ+K+ E + +S T RS + K+ D+ + + +++L++ G + Sbjct: 605 LVVTRNGQIKQIERESFSPWRTYRSKSTPYAKLKGEDDEIVLITPVQFADLMLISENGYA 664 Query: 661 IRFRENEVNPMGRVASGVRGIQLREGDEVVSCFWVNEDEGEILAVTEIGYAKRTLLLDYP 720 +RF ++V +G A+GV+ + L+ GD++ S F+VN + +L T+ + KR D P Sbjct: 665 LRFNLDDVPVLGARAAGVKAMNLKNGDKIKSAFFVNSNSWYLL--TQRAFIKRVKTDDIP 722 Query: 721 AQSRGGKGMPTFEFKEGKRVRPNGSRISGAFYCREPLELVAITREGATHSFSSESAPLSE 780 A SR +G+ + ++ N + A +L A+T E FS AP ++ Sbjct: 723 ATSRANRGLQVL-----RTLKTNNHTVFAAGLINSTADLSALTEE--LDLFSQAKAPATK 775 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 56,739,847 Number of extensions: 2320495 Number of successful extensions: 13168 Number of sequences better than 1.0e-05: 79 Number of HSP's gapped: 12720 Number of HSP's successfully gapped: 94 Length of query: 805 Length of database: 38,378,431 Length adjustment: 115 Effective length of query: 690 Effective length of database: 25,115,021 Effective search space: 17329364490 Effective search space used: 17329364490 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 120 (50.8 bits)