BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0349.0007.p (332 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0751 [R] COG1277 ABC-type transport system involved in multi-... 343 1e-94 BS_yhcI [R] COG1277 ABC-type transport system involved in multi-... 99 8e-21 CAC0140 [R] COG1277 ABC-type transport system involved in multi-... 91 3e-18 CAC0139 [R] COG1277 ABC-type transport system involved in multi-... 82 1e-15 CAC0146 [R] COG1277 ABC-type transport system involved in multi-... 79 1e-14 >lin0751 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component Length = 326 Score = 343 bits (881), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 167/325 (51%), Positives = 229/325 (70%), Gaps = 1/325 (0%) Query: 7 LIPLIRNECLKIIKKKRFYXXXXXXXXXXPMFTYAQMR-IADRNKDKFNSDWRLEIQQQI 65 +I L+ NE LK+ +KKR +FTYAQ R + K SDW ++ QQQI Sbjct: 1 MINLVYNEQLKLWRKKRLIVILALVAIIVAIFTYAQFRQYQEDEKQAGTSDWHVQTQQQI 60 Query: 66 TDNQNSLGSDRIPEEWKSYRKIFVQQLQYYLDHDVNPNEPSGVTFTREFLDNSVSLFIPL 125 D +N LG+ R+PEE++ Y K+ V QLQYYLD+D+NPN P TF + F++N +SL PL Sbjct: 61 VDLENRLGTGRLPEEYQKYFKVLVGQLQYYLDNDINPNAPGAPTFLKTFVENGISLLFPL 120 Query: 126 LIMAVASDLVSGERTTGTIKMLLTRPVKRWKVLFSKMAALLMFVSLIVLAAFVISYLISG 185 IM +A+DL+S E + GT+K LLTRPVKRW++L SK ++L+ +S I++ + VI+YLISG Sbjct: 121 FIMVIAADLISAETSAGTMKFLLTRPVKRWRILTSKYISMLLSISAIMVLSAVIAYLISG 180 Query: 186 LAFGYKGFNVPVFTGFQLNGDTVDMSAVHAVPQWKYLLMQGGLIWFVSVVVALLAFMVSV 245 + FGY G++ PV TGF + + + V+ +P W+ LLM+ GL WFVSVVV +L VSV Sbjct: 181 IVFGYGGWDAPVLTGFGVKDGAITTTNVYQLPVWQLLLMEFGLAWFVSVVVGVLTMFVSV 240 Query: 246 LVRSTAASIVVMMAALIAGTILTNMASAWTTAKYLFMVNLGLTGYLAGSPAPIEGMTLSF 305 LVRSTAA + +M+A+LI GTILTN+ S+W +AKYLFMVNL LT YL GS P+EGMTL+F Sbjct: 241 LVRSTAAVMGIMLASLITGTILTNLVSSWPSAKYLFMVNLQLTNYLNGSSPPVEGMTLNF 300 Query: 306 SMGVLAVWGILSVIISFAVFTKRDI 330 SM VL W +++ I+S+ +FTKRD+ Sbjct: 301 SMLVLTAWMVVAFILSYFIFTKRDV 325 >BS_yhcI [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component Length = 313 Score = 99.0 bits (245), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 90/330 (27%), Positives = 168/330 (50%), Gaps = 21/330 (6%) Query: 7 LIPLIRNECLKIIKKKRFYXXXXXXXXXXPMFTYAQMRIADRNKDKFNSDWRLEIQQQIT 66 ++ LI NE LKI + + F + + + NS W+ E+Q Q Sbjct: 1 MLNLIYNEWLKIFSRAGTWVMIGILGLTMVGFAFLANHFS---AGESNSHWKQELQAQNA 57 Query: 67 DNQNSLGSDRIPEEWKSYRKIFVQQLQYYLDHDVNPNEPSGVTFTR-EFLDNSVSLFI-- 123 + + + D P Y++ D+ + N PS +T ++ +S + I Sbjct: 58 ELKKEIKED--PSLKDGYKETITLN-----DYRIEHNIPSDTGYTVWSYVTDSANFTILT 110 Query: 124 PLLIMAVASDLVSGERTTGTIKMLLTRPVKRWKVLFSKMAALLMFVSLIVLAAFVISYLI 183 L + +A+ +V+ E GTIK+L+ RP+ R+++L SK +L+F L++L F+ S L+ Sbjct: 111 GLFTIIIAAGIVANEFNWGTIKLLMIRPLSRFQILMSKYITVLLFGLLLLLILFIGSTLL 170 Query: 184 SGLAFGYKGFNVPVFTGFQLNGDTVDMSAVHAVPQWKYLLMQGGLIWFVSVVVALLAFMV 243 + FG G +G ++ + + + YL +++VA +AFM+ Sbjct: 171 GLIFFGTGGETAANIHLIYKDGHVIEQNMMGHLAT-TYLSES-----VSALMVATMAFML 224 Query: 244 SVLVRSTAASIVVMMAALIAGTILTN-MASAWTTAKYLFMVNLGLTGYLAGSPAPIEGMT 302 S + R+++ ++ + L+AGT T +A+ + AKY+ N+ LT Y+ G+P I+GMT Sbjct: 225 SAVFRNSSLAVGFSIFLLVAGTTATAFIAAKFDWAKYILFANVDLTQYVDGTPL-IKGMT 283 Query: 303 LSFSMGVLAVWGILSVIISFAVFTKRDILN 332 ++FS+ +LA++ I+ ++++F +F KRDI N Sbjct: 284 MTFSLVMLAIYFIIFLLLAFGIFMKRDIAN 313 >CAC0140 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component Length = 405 Score = 90.9 bits (224), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 90/324 (27%), Positives = 160/324 (49%), Gaps = 36/324 (11%) Query: 42 QMRIADRNKDKFNSDWRLEIQQQITDNQNSLGSDRIPEEWKSYRKIFVQQL--QYYLDHD 99 +++ A R +D +W+ I+ QI+D++ I + ++ Q L +Y L + Sbjct: 83 EIQEAYRAEDLDKLNWKDRIKYQISDDEKKKKLPDIVSDDTKIEQVNAQILSKKYALKNS 142 Query: 100 V-----NPNEPSGVTFTREFLDNSVSLFI-PLLIMAVASDLVSGERTTGTIKMLLTRPVK 153 V + NE + F + + + VSL I P++I + D+VSGE + T+KMLLT+P Sbjct: 143 VPDAADDYNEKALDVFIK--MVSYVSLIILPVIICVIVLDVVSGECSPPTMKMLLTKPFS 200 Query: 154 RWKVLFSKMAALLMFVSLIVLAAFVISYLISGLAFGYKGFNVPVFTG--FQLNGDTV--- 208 R K+LFSK A + + ++ + +IS +I G+ G+ N PV G +Q N D V Sbjct: 201 RGKILFSKFMAASIASIIAIVFSELISLIILGIVIGFGSINAPVSLGTKYQFNADKVLAG 260 Query: 209 ---DMSAV----HAVPQWKYLLMQGGLIWFVSVVVALLAFMVSVLVRSTAASIV--VMMA 259 D+ A+ + PQWK +L GL + + ++SVLV S S+ +++A Sbjct: 261 NWHDVKAIIGSTYVEPQWKVMLEMFGLEILFILAFTSICILISVLVNSNTVSMTSGIIIA 320 Query: 260 ALIAGTILTNMASAWTTAKYL-------FMVN-LGLTGYLAGSP--APIEGMTLSFSMGV 309 +++ +L MA ++A + +++N G+L + I +S +GV Sbjct: 321 VIMSFIVLKIMAGDGSSAGDVPFRKIAPYLINTYSSPGFLLSGDMTSQIRNPDISVGLGV 380 Query: 310 L--AVWGILSVIISFAVFTKRDIL 331 L + G + II+ FT++D+L Sbjct: 381 LVNVITGAVCYIIAHIRFTRKDML 404 >CAC0139 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component Length = 404 Score = 82.4 bits (202), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 81/304 (26%), Positives = 150/304 (49%), Gaps = 29/304 (9%) Query: 56 DWRLEIQQQITDNQNSLGSDRIP--EEWKSYRKIFVQQLQYYLDHDVNPNEPSGVTFTRE 113 DW L + +++ + D+ E I V + +YY D+++NP + +G Sbjct: 101 DWHLRLNKELIQKKYEYIKDKGKGKNEDTEDASISVMKDEYYRDNNLNPYDKTGDLAMDS 160 Query: 114 FLDNS--VSLFIPLLIMAVA-SDLVSGERTTGTIKMLLTRPVKRWKVLFSKMAALLMFVS 170 FL + + + + +I+AVA SD+VS E + TIKMLL +P R K+LFSK A+L+ Sbjct: 161 FLSSKAFMQILVVFIIIAVATSDIVSSEYSPATIKMLLAKPASRAKILFSKFIAILVGNI 220 Query: 171 LIVLAAFVISYLISGLAFGYKGFNVPVFTGFQLNGDTVDMSAVHAVP-----QWKYLLMQ 225 I+ VI+YLI G+ + P+ G D+ + + H V YL+ + Sbjct: 221 FIIGIPQVITYLILSFMNGFPNLSQPIAVGRMYQYDSSVILSNHNVGVSPILGSSYLITE 280 Query: 226 GGLIWFVSVVVAL-------LAFMVSVLVRSTAASIVVMMAALIAGTILTNMASAWTTAK 278 G + +++++ L + F++SVL++++A +I + + + +I+ M K Sbjct: 281 GKYLLYLALLDLLFILGCVSICFLISVLIKNSAITIGINVGLGVVMSIIGLMTLEGAIPK 340 Query: 279 YL-----FMV------NLGLTGYLAGSPAPIEGMTLSFSMGVLAVWGILSVIISFAVFTK 327 L F++ ++ L G +A A G+T+ + V V+ ++ + IS VF+K Sbjct: 341 ALSAITPFLIMTYSSTDVLLMGDMAKR-ANNPGITVGMGIVVFIVYTVVCMGISTFVFSK 399 Query: 328 RDIL 331 +D+L Sbjct: 400 KDML 403 >CAC0146 [R] COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component Length = 395 Score = 78.6 bits (192), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 80/312 (25%), Positives = 160/312 (51%), Gaps = 27/312 (8%) Query: 42 QMRIADRNKDKFNSDWRLEIQQQI---TDNQNSLGSDRIPEEWKSYRKIFVQQLQYYLDH 98 Q++ ++K++ NS+W+ +++ I D +N +SY K V QY L+H Sbjct: 86 QIKQYQQSKNQGNSNWKKQLKNTIDSLKDEKNQAADITENTAKESYNKQIVF-YQYLLNH 144 Query: 99 DVNPNEPSGVTFTREFLDNSVSLFIPLLIMAV----ASDLVSGERTTGTIKMLLTRPVKR 154 ++ P + + ++ T + L + + L +LI + ++D+VSGE T TIK+LL++P R Sbjct: 145 NIKPQDNNSLS-TFQLLQSLLKLIGYILIPIIIAIFSADIVSGEYTPPTIKVLLSKPASR 203 Query: 155 WKVLFSKMAALLMFVSLIVLAAFVISYLISGLAFGYKGFNVPVF-------TGFQLNGDT 207 K+L SK A + I+L +I+YLI+G+A+G+ + PV +G +L D+ Sbjct: 204 AKILASKFIASAISCIAIILLIELITYLITGIAYGFDNPSYPVLVGTKYMNSGIKLTQDS 263 Query: 208 VD----MSAVHAVPQWKYLLMQGGLIWFVSVVVALLAF--MVSVLVRSTAASIVVMMAAL 261 + + + +P W++L+ ++ + ++ +F ++SV++RS+ S+ + + + Sbjct: 264 TGLIPILGSSYVIPLWQFLIEM--FLFQILFIIGCCSFFLLLSVVLRSSVLSMTLSIMIV 321 Query: 262 IAGTILTNMASAWTTAKYLFMVNLGLTGYLAGSPAPIEGMTLS---FSMGVLAVWGILSV 318 IA I++ +++ +LF L S G+T + F + L ++ IL Sbjct: 322 IALNIISQISALHVIMPFLFTNYGSPYDILTNSIPSTSGLTFTTAIFGVIYLIIFTILCY 381 Query: 319 IISFAVFTKRDI 330 I+ F K+D+ Sbjct: 382 GIANYSFKKKDM 393 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.326 0.138 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,393,566 Number of extensions: 888049 Number of successful extensions: 2860 Number of sequences better than 1.0e-05: 10 Number of HSP's gapped: 2851 Number of HSP's successfully gapped: 10 Length of query: 332 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 225 Effective length of database: 26,037,693 Effective search space: 5858480925 Effective search space used: 5858480925 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 116 (49.3 bits)