BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0349.0006.p (326 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase ... 298 7e-81 BS_yhcH [V] COG1131 ABC-type multidrug transport system, ATPase ... 293 2e-79 CAC0138 [V] COG1131 ABC-type multidrug transport system, ATPase ... 268 6e-72 BS_ydbJ [V] COG1131 ABC-type multidrug transport system, ATPase ... 262 6e-70 CAC0147 [V] COG1131 ABC-type multidrug transport system, ATPase ... 244 1e-64 >lin0750 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 301 Score = 298 bits (763), Expect = 7e-81, Method: Compositional matrix adjust. Identities = 163/316 (51%), Positives = 214/316 (67%), Gaps = 19/316 (6%) Query: 12 VVLSVEGVRKKIGRKWIIDDVTFDVREGEVFGFLGPNGAGKTTTIRMLVDLIRPSEGEIT 71 + L V + KKI ++ II ++F+VR GEVFGFLGPNGAGKTTTIRM+V LI+P+ G I Sbjct: 4 LALQVTNLHKKIRKREIIKGISFEVRPGEVFGFLGPNGAGKTTTIRMIVGLIKPTSGTIL 63 Query: 72 VCGYNVNRQPEKALQYVGSIVENPEVYTYLTGWENLQHFARMQPGVDKARIDEVVDIVRL 131 + G ++ + +A++ +GSIVENPE YT+LTG ENL +FARM P + K RI EV ++V L Sbjct: 64 IGGKDIRKNFTEAMRGLGSIVENPEFYTFLTGQENLAYFARMDPSIKKERIQEVTELVGL 123 Query: 132 DQRIHDKVSTYSLGMRQRLGIAQALLGRPRLLILDEPTNGLDPKGIKELREFIRQLA-AE 190 ++RI+D+VSTYSLGMRQRLGIAQALL P+LLILDEPTNGLDP GI E+R+FIR LA E Sbjct: 124 EKRINDRVSTYSLGMRQRLGIAQALLSSPKLLILDEPTNGLDPSGIHEMRDFIRALARNE 183 Query: 191 GLAVFVSSHLLSEIQLLCDRVAIISKGRVLAVGGVEDLVARNSPYVLWELEPLSRAKKIL 250 G++V VSSHLLSEI+LLCDRVAI++ G ++ V L++ + + W P +AK L Sbjct: 184 GISVLVSSHLLSEIELLCDRVAIMTDGTIIKTDQVSHLLSSRA-QLRWLATPFEQAKAFL 242 Query: 251 GSRPDISLMELDEVTLDDSIIAGMGANSLVTVMEEDLIPEIVAVLVTAEVEVRAVHKINP 310 S + EV +D LVT + E E LV ++V + K P Sbjct: 243 AS--------VTEVEVD--------GEYLVTAVNER-SAEWNEQLVAKGIQVHEIDKKKP 285 Query: 311 TLEQLFLKLTEGETID 326 +LE LFL+LT G +ID Sbjct: 286 SLEDLFLELTGGHSID 301 >BS_yhcH [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 154 Score = 293 bits (750), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 0/313 (0%), Positives = 0/313 (0%), Gaps = 19/313 (6%) Query: 13 VLSVEGVRKKIGRKWIIDDVTFDVREGEVFGFLGPNGAGKTTTIRMLVDLIRPSEGEITV 72 + + G + ++ + + Sbjct: 4 GEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDNIFMNVMTFNTQSPVEKKAE 63 Query: 73 CGYNVNRQPEKALQYVGSIVENPEVYTYLTGWENLQHFARMQPGVDKARIDEVVDIVRLD 132 + + + + ++ I + + Sbjct: 64 LHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQLCSTIDNEQAIILKPGMFAVF 123 Query: 133 QRIHDKVSTYSLGMRQRLGIAQALLGRPRLLILDEPTNGLDPKGIKELREFIRQLAAE-G 191 Sbjct: 124 183 Query: 192 LAVFVSSHLLSEIQLLCDRVAIISKGRVLAVGGVEDLVARNSPYVLWELEPLSRAKKILG 251 Sbjct: 184 243 Query: 252 SRPDISLMELDEVTLDDSIIAGMGANSLVTVMEEDLIPEIVAVLVTAEVEVRAVHKINPT 311 Sbjct: 244 ----------------- 286 Query: 312 LEQLFLKLTEGET 324 Sbjct: 287 - 298 >CAC0138 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 312 Score = 268 bits (686), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 144/314 (45%), Positives = 203/314 (64%), Gaps = 15/314 (4%) Query: 12 VVLSVEGVRKKIGRKWIIDDVTFDVREGEVFGFLGPNGAGKTTTIRMLVDLIRPSEGEIT 71 VVL V+ V+K IG++ II ++F V EG++FGFLGPNGAGKTTTIRMLV LI+P+ G I Sbjct: 3 VVLEVKDVKKHIGKREIIKGISFSVEEGQIFGFLGPNGAGKTTTIRMLVGLIKPNSGSIK 62 Query: 72 VCGYNVNRQPEKALQYVGSIVENPEVYTYLTGWENLQHFARMQPGVDKARIDEVVDIVRL 131 + G+++ ++ EKAL VG IVENP++Y +LTG ENL +A+M V K RIDEV +I+ L Sbjct: 63 IMGHDIQKEKEKALSNVGCIVENPDMYGFLTGRENLIQYAKMYGSVSKERIDEVAEIIGL 122 Query: 132 DQRIHDKVSTYSLGMRQRLGIAQALLGRPRLLILDEPTNGLDPKGIKELREFIRQLAAEG 191 RI+DKV YSLGM+QRLG+ QALL RP+LLILDEPTNGLDP GI + R +R +A E Sbjct: 123 KDRINDKVKKYSLGMKQRLGLGQALLVRPKLLILDEPTNGLDPVGIMDFRRIVRLMAEEN 182 Query: 192 L-AVFVSSHLLSEIQLLCDRVAIISKGRVLAVGGVEDLVARNSPYVLW-ELEPLSRAKKI 249 AVF+SSH+L+EIQ +CD VA I+ G + +V ++ + + ++ A + Sbjct: 183 KSAVFISSHILAEIQQVCDTVAFINGGEIKSVESTKESEGKGTKENFGIATSNINLAMET 242 Query: 250 LGSRPDISLMELDEVTLDDSIIAGMGANSLVTVMEEDLIPEIVAVLVTAEVEVRAVHKIN 309 L P + ++ +E + +I G P+++A L+ VEV +K + Sbjct: 243 LSKLPFVYEVKNNEDKISAAIQYGTS-------------PKVIAELMKNSVEVIEFYKEH 289 Query: 310 PTLEQLFLKLTEGE 323 TLE F+++ EGE Sbjct: 290 KTLEDRFMQIVEGE 303 >BS_ydbJ [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 308 Score = 262 bits (669), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 141/309 (45%), Positives = 199/309 (64%), Gaps = 17/309 (5%) Query: 13 VLSVEGVRKKIGRKWIIDDVTFDVREGEVFGFLGPNGAGKTTTIRMLVDLIRPSEGEITV 72 +L +EG+ KKIG K I+ ++ DV EGE+ G LGPNG+GKTT IR++V L++ + G +T+ Sbjct: 5 ILHIEGLDKKIGSKQILKQISMDVMEGEIIGLLGPNGSGKTTLIRIIVGLLKQNSGSVTI 64 Query: 73 CGYNVNRQPEKALQYVGSIVENPEVYTYLTGWENLQHFARMQPGVDKARIDEVVDIVRLD 132 G+ + + EKA++ VG+IVENPE Y YLTGWENL+HFA M + R+DEVV+ V L Sbjct: 65 SGFQHDTEFEKAMEAVGAIVENPEFYPYLTGWENLKHFANMHKKIADERLDEVVERVGLT 124 Query: 133 QRIHDKVSTYSLGMRQRLGIAQALLGRPRLLILDEPTNGLDPKGIKELREFIRQLAA-EG 191 IHDKV TYSLGMRQRLGIAQA+L RP+LLILDEPTNGLDP G+K+ R+ I++LA EG Sbjct: 125 SAIHDKVKTYSLGMRQRLGIAQAILHRPKLLILDEPTNGLDPAGMKDFRDHIKELAEMEG 184 Query: 192 LAVFVSSHLLSEIQLLCDRVAIISKGRVLAVGGVEDLVARNSPYVLWELEPLSRAKKILG 251 AV ++HLL E++ LCDRV II KG + A ++ + + + E++P +A Sbjct: 185 TAVLFATHLLREVEDLCDRVIIIQKGEIKAEVSLQG-TDQTTEKAIIEVQPQEKA----- 238 Query: 252 SRPDISLMELDEVTLDDSIIAGMGANSLVTVMEEDLIPEIVAVLVTAEVEVRAVHKINPT 311 L+ +T + +V V +E+ IPE+ LV ++ V ++ + Sbjct: 239 ---------LNWLTGNQYQAESQDGTIVVEVAKEN-IPELNRSLVGQDLNVFSITPYTQS 288 Query: 312 LEQLFLKLT 320 LE F+K T Sbjct: 289 LEDEFIKAT 297 >CAC0147 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 318 Score = 244 bits (623), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 129/314 (41%), Positives = 192/314 (61%), Gaps = 11/314 (3%) Query: 13 VLSVEGVRKKIGRKWIIDDVTFDVREGEVFGFLGPNGAGKTTTIRMLVDLIRPSEGEITV 72 VL V + KK+G K II ++F ++EGE+ GFLG NGAGKTTTI+MLV LI P +G + + Sbjct: 4 VLEVTDLYKKLGNKEIIKGISFSIKEGEILGFLGRNGAGKTTTIKMLVGLITPDKGSVMI 63 Query: 73 CGYNVNRQPEKALQYVGSIVENPEVYTYLTGWENLQHFARMQPGVDKARIDEVVDIVRLD 132 G+++ ++ E+AL VG++VENPE+Y+YLTG +NL+ AR + K I+++ + V L Sbjct: 64 SGHDITKEAEEALSCVGAVVENPELYSYLTGRQNLEQVARFYKDITKEDIEKIGNTVGLS 123 Query: 133 QRIHDKVSTYSLGMRQRLGIAQALLGRPRLLILDEPTNGLDPKGIKELREFIRQLAAEG- 191 R+ +KV YSLGM+QRLG+A+AL+ +P+LLILDEPTNGLDP GI E R +++ A E Sbjct: 124 GRLDEKVKKYSLGMKQRLGLAEALISKPKLLILDEPTNGLDPTGIIEFRNLLKKQAKENK 183 Query: 192 LAVFVSSHLLSEIQLLCDRVAIISKGRVLAVGGVEDLVARNSPYVLWELEPLSRAKKILG 251 +A+FVSSH+LSEI+ LCDRVA I G + E L N + E + I+ Sbjct: 184 MAIFVSSHILSEIEQLCDRVAFIDGG---IIKSFETLKGTNKDHKTESFENVV----IMT 236 Query: 252 SRPDISLMELDEVTLDDSIIAGMGANSLVTVMEE---DLIPEIVAVLVTAEVEVRAVHKI 308 D L E++ +N + T + D +P+I + L ++ + ++K Sbjct: 237 KEKDKCTEALKEISFIIDFKLADESNGIYTFEAKAKLDSVPDITSSLAEKKIRIEQIYKR 296 Query: 309 NPTLEQLFLKLTEG 322 LE +++L G Sbjct: 297 QQNLEDRYIELVNG 310 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.139 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 24,769,227 Number of extensions: 1080821 Number of successful extensions: 9316 Number of sequences better than 1.0e-05: 2134 Number of HSP's gapped: 6595 Number of HSP's successfully gapped: 2374 Length of query: 326 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 219 Effective length of database: 26,037,693 Effective search space: 5702254767 Effective search space used: 5702254767 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 116 (49.3 bits)