BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0346.0078.p (252 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value yagI [K] COG1414 Transcriptional regulator 107 3e-23 BH2137 [K] COG1414 Transcriptional regulator 104 1e-22 DR1156 [K] COG1414 Transcriptional regulator 98 1e-20 BMEI0387 [K] COG1414 Transcriptional regulator 96 7e-20 BH3725 [K] COG1414 Transcriptional regulator 94 2e-19 >yagI [K] COG1414 Transcriptional regulator Length = 252 Score = 107 bits (266), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 118/249 (47%), Gaps = 31/249 (12%) Query: 7 VPALERADLILTAISRKPGEYKMTDLCDATGINKSSMFSLLRTMEALNWVTKD-EKEAYA 65 + ++ERA IL + + E K+TD+ G++KS++ SLL+T++ ++ ++ E Y Sbjct: 4 IQSVERALQILDLFNEQATELKITDISKLMGLSKSTLHSLLKTLQLHGYIDQNPENGKYR 63 Query: 66 LGAGVAYLNKVFNESHKQNYNLVE--HFLKAS-----------AESIKAVGETFQLSVLD 112 LG LVE HF+ S E + G+T L +LD Sbjct: 64 LG-----------------MKLVERGHFVVGSIDIRQKAKGWLTELSRRTGQTTHLGILD 106 Query: 113 RSEIIYLAKLEGPSLVKLESSPGMRFPAHATAMGKMMLALLPPDELDRRYPDRILTPVTS 172 E +Y+ K+EG S G R P HATA+GK+++A L EL+ T T Sbjct: 107 GREGVYIEKIEGKLAAIAYSRIGRRLPVHATAIGKVLIAWLGEAELNALLEGYQYTTFTP 166 Query: 173 HTLTDWSEFTATLAEIRSSGYSVDQEEIIQGICCVAAPVLDASGNAVAAVSTSMLRHAYL 232 TL + LA+ R GY++D EE QG+ CVA PV + +AA+S S L Sbjct: 167 ATLASREALMSALAQTREQGYALDSEENEQGVRCVAVPVWNHESRVIAALSLSTLTSRVD 226 Query: 233 DKQEAAIQE 241 D + A +E Sbjct: 227 DAELANFRE 235 >BH2137 [K] COG1414 Transcriptional regulator Length = 251 Score = 104 bits (260), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 75/227 (33%), Positives = 113/227 (49%), Gaps = 17/227 (7%) Query: 6 WVPALERADLILTAISRKPGEYKMTDLCDATGINKSSMFSLLRTMEALNWVTKDEK-EAY 64 V +++RA I++ +S +TD+ + KSS + LL T+ ++ +DE+ + Y Sbjct: 1 MVKSVDRALTIISLVSEHKQGLGVTDVAAKLSLTKSSAYKLLATLVEHGFIEQDEETKKY 60 Query: 65 ALGAGVAYLNKVFNES---HKQNYNLVEHFLKASAESIKAVGETFQLSVLDRSEIIYLAK 121 LG L+ ES +Q +E L+A+ E L + D+ E++Y+ K Sbjct: 61 RLGYRYLELSATLLESIDIRRQARPFLEQ-LEATT------NEVVHLVLYDQGEMVYIDK 113 Query: 122 LEGPSLVKLESSPGMRFPAHATAMGKMMLALLPPD---ELDRRYPDRILTPVTSHTLTDW 178 LEG ++ S G R P H T++GK+++A LP L RY L P T T+TD Sbjct: 114 LEGTKTLRTHSKIGRRAPIHCTSVGKVIMAYLPEKVQISLIERYG---LPPHTERTITDK 170 Query: 179 SEFTATLAEIRSSGYSVDQEEIIQGICCVAAPVLDASGNAVAAVSTS 225 F L +IR GY + EE GI C+AAP+ D G AAVS S Sbjct: 171 ETFMKELEKIRLEGYGYEMEENEPGITCIAAPIFDYQGAITAAVSIS 217 >DR1156 [K] COG1414 Transcriptional regulator Length = 267 Score = 97.8 bits (242), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 67/227 (29%), Positives = 113/227 (49%), Gaps = 20/227 (8%) Query: 7 VPALERADLILTAISRKPGEYKMTDLCDATGINKSSMFSLLRTMEALNWVTKDEK----- 61 V LER +L+A++ + E +T + G++ S+ + LL T+ +V +E+ Sbjct: 20 VRTLERGLSVLSALA-ELREATLTQVAKKAGLSASTTYRLLETLRQQGYVEWEERSGLFS 78 Query: 62 ---EAYALGAGVAYLNKVFNESHKQNYNLVEHFLKASAESIKAVGETFQLSVLDRSEIIY 118 AY +GA + N + + + LVE V ET L+VL +E +Y Sbjct: 79 VGLRAYQVGAAFSERNSLLSAAGAVMQALVEE-----------VNETANLAVLRGNEAVY 127 Query: 119 LAKLEGPSLVKLESSPGMRFPAHATAMGKMMLALLPPDELDRRYPDRILTPVTSHTLTDW 178 + ++E L+++ + G P H + +GK++ A LPP E+ R+ D T H++T Sbjct: 128 VHQVEASQLMRMFTHIGAAAPLHCSGVGKVLTAWLPPAEVRRKVGDGPFPAYTPHSITTL 187 Query: 179 SEFTATLAEIRSSGYSVDQEEIIQGICCVAAPVLDASGNAVAAVSTS 225 + T L +R Y++D EE G+ C+A PV ASG VA++S S Sbjct: 188 AALTRELNTVRGQDYALDDEERELGVRCLATPVRAASGEVVASLSVS 234 >BMEI0387 [K] COG1414 Transcriptional regulator Length = 273 Score = 95.5 bits (236), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 70/229 (30%), Positives = 116/229 (50%), Gaps = 14/229 (6%) Query: 7 VPALERADLILTAISR-------KPGE-YKMTDLCDATGINKSSMFSLLRTMEALNWVTK 58 VPA+ RA IL I+R + GE K+++L T + KSS+ L +T+ L + Sbjct: 17 VPAVMRAAQILDQIARATQEGGKRSGEGMKLSELARQTALPKSSVHGLCQTLVHLKLLKL 76 Query: 59 DEKEAYALGA-GVAYLNKVFNESHKQNYNLVEHFLKASAESIKAVGETFQLSVLDRSEII 117 + ++++G V + N +S ++VE F +A AE++ T LS L+ E+I Sbjct: 77 NGDGSFSMGPQSVRWANVFLAQS-----DIVEAFHEAVAEAVGLGAYTLTLSHLEGPEVI 131 Query: 118 YLAKLEGPSLVKLESSPGMRFPAHATAMGKMMLALLPPDELDRRYPDRILTPVTSHTLTD 177 YL+ + + + GMR PA TA GK MLA + P EL + P PVT +++ Sbjct: 132 YLSCRNSSAPLGITFRIGMRVPAVFTATGKAMLAAMSPRELTQHLPSEWPGPVTPTSVSS 191 Query: 178 WSEFTATLAEIRSSGYSVDQEEIIQGICCVAAPVLDASGNAVAAVSTSM 226 + + E GYS+D ++ +G+ C+ A + D + VA ++ SM Sbjct: 192 LAALEKEMGEAVIKGYSLDNGQLREGMFCIGAAICDRPFHPVAGIALSM 240 >BH3725 [K] COG1414 Transcriptional regulator Length = 251 Score = 94.4 bits (233), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 65/223 (29%), Positives = 112/223 (50%), Gaps = 8/223 (3%) Query: 6 WVPALERADLILTAISRKPGEYKMTDLCDATGINKSSMFSLLRTMEALNWVTKD-EKEAY 64 V +++RA +IL + + P +T+L + KS+ L+ T+E ++VT+D E Y Sbjct: 1 MVQSVDRALMILDILKQHPKGLGITELAHELNVAKSTAHRLVSTLETYDYVTQDRETSRY 60 Query: 65 ALGAGVAYLNKVFNESHKQNYNLVEH-FLKASAESIKAVGETFQLSVLDRSEIIYLAKLE 123 +LG + +V E+ + V H L+A E GE L + D +++Y+ K+E Sbjct: 61 SLGLKFLEMQQVVMEN--MDIVAVAHPILEALTEE---CGEISHLVMRDHFDVVYIDKVE 115 Query: 124 GP-SLVKLESSPGMRFPAHATAMGKMMLALLPPDELDRRYPDRILTPVTSHTLTDWSEFT 182 S +++ S G R P + TA+GK + A L P+T HT+++ F Sbjct: 116 SAVSTIRIYSRTGKRAPIYCTAVGKAIAAHFDEPLLQEYVEQAAFQPLTRHTISEPEAFK 175 Query: 183 ATLAEIRSSGYSVDQEEIIQGICCVAAPVLDASGNAVAAVSTS 225 A L ++ + GY+ D EE +GI C+ AP+ + G A+S + Sbjct: 176 AALQKVLTDGYAEDNEEHEEGIRCIGAPIFNHLGQVPYAISIT 218 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.317 0.131 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 17,305,525 Number of extensions: 704153 Number of successful extensions: 2258 Number of sequences better than 1.0e-05: 61 Number of HSP's gapped: 2213 Number of HSP's successfully gapped: 61 Length of query: 252 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 148 Effective length of database: 26,383,695 Effective search space: 3904786860 Effective search space used: 3904786860 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)