BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0346.0008.p (331 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value CAC0693 [K] COG1609 Transcriptional regulators 342 7e-94 CC1489 [K] COG1609 Transcriptional regulators 163 4e-40 YPO0611 [K] COG1609 Transcriptional regulators 160 2e-39 HI0506 [K] COG1609 Transcriptional regulators 160 2e-39 SMb20014 [K] COG1609 Transcriptional regulators 156 4e-38 >CAC0693 [K] COG1609 Transcriptional regulators Length = 334 Score = 342 bits (876), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 159/327 (48%), Positives = 232/327 (70%) Query: 2 ITIKDIARVAGVSHTTVSRALNGSPLIKKVTRDKIEKIAAEMNYVPNYSAKSLVTKRSFT 61 +TIKDIA++A VSHTTVSRALN SP+I + T+ KI +IA ++NYVPN++AKSLV +S+ Sbjct: 3 VTIKDIAKIANVSHTTVSRALNNSPVINEETKRKILEIAKKLNYVPNFNAKSLVLNKSYN 62 Query: 62 IGLFFSSIEQGTSASFLVDAIKGISHILDENFNLTVNGIDGVHNFGNIQPQRFDGILVMS 121 IGLFFSSI +GTS SF + ++G++ I++E++NL + GID ++F I +RFDGI+++S Sbjct: 63 IGLFFSSISKGTSPSFFHEVVEGVNSIIEESYNLVIKGIDNCNDFNYISKKRFDGIILVS 122 Query: 122 QSDEDNAFIYHVKKMGIPLVVLNRQLEDPGIMNVVANDREGVKEAIDYAVRQGHRKLAII 181 QS+ DN+FIY V IP+VVLNR++E+ ++N++A +++G +A +Y ++ GH K+AII Sbjct: 123 QSESDNSFIYDVINKEIPIVVLNREIEEQNVINIIAAEKDGAYKAAEYLIKNGHSKIAII 182 Query: 182 EGKPGFKSSSERKQGFMDSLIAHRLPLNSGYFAAGDYSIESGYAAMAALLQLEDPPTAVF 241 EGK GFKSS RK GF+++LI + + + + YF AG+Y +ESG++AM L+L+D PTAVF Sbjct: 183 EGKAGFKSSVYRKMGFINALIDNNIEIKNEYFQAGNYDVESGFSAMKKFLKLKDRPTAVF 242 Query: 242 CSNDDMAIGAMNACYAHKADVPGQISLLGFDDIMFSRYTNPALTTVRKPITEISELGTKM 301 CSNDDMA+GA+ A VP ISL+GFD +F Y PA+TT+RKP EI +G Sbjct: 243 CSNDDMAVGAVKAIELEGLRVPDDISLVGFDGSIFCEYVTPAITTIRKPSREIGIVGANK 302 Query: 302 XXXXXXXXXXXXXXXFVNTSLVIRQTV 328 ++ T L++R +V Sbjct: 303 MLDVIDETEFNKKKIYIGTELIVRDSV 329 >CC1489 [K] COG1609 Transcriptional regulators Length = 357 Score = 163 bits (412), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 100/310 (32%), Positives = 157/310 (50%), Gaps = 21/310 (6%) Query: 3 TIKDIARVAGVSHTTVSRALNGSPLIKKVTRDKIEKIAAEMNYVPNYSAKSLVTKRSFTI 62 TI DIAR+AGVS TVSR +N SP ++ TR++IE + AE Y P+ A+ L +RSF I Sbjct: 26 TINDIARLAGVSKKTVSRVINQSPFVRDETRERIEAVIAEWGYAPDPQARGLAFRRSFLI 85 Query: 63 GLFFSSIEQGTSASF---LVDAIKGISHILDENFNLTVNGID--------GVHNFGNIQP 111 G+ + + + L+D ++G F L V+ + + F ++ Sbjct: 86 GMIYDNPNPQYVVNMQLGLLDGMRG------SGFELVVHPCNRASPTFLTDIRAF--VER 137 Query: 112 QRFDGILVMSQSDEDNAFIYHVKKMGIPLV-VLNRQLEDPGIMNVVANDREGVKEAIDYA 170 Q+ G+++ ED + ++G + + + +L+ P M +V DR G +A + Sbjct: 138 QKLFGVVLPPSVSEDERVAKLLNEIGCAYIRIASVELDKPEHM-IVGQDRMGGAQAARHI 196 Query: 171 VRQGHRKLAIIEGKPGFKSSSERKQGFMDSLIAHRLPLNSGYFAAGDYSIESGYAAMAAL 230 V GH+++A I G F+SS ER+ GF D L L L+ G Y+ ESG A L Sbjct: 197 VELGHKRIAFISGPETFRSSHERRGGFEDGLAEAGLSLSPNDIVQGAYTFESGVACGDEL 256 Query: 231 LQLEDPPTAVFCSNDDMAIGAMNACYAHKADVPGQISLLGFDDIMFSRYTNPALTTVRKP 290 L PTA+FC ND+MA G + + VP ++++GFDD ++ P LTT+ P Sbjct: 257 LSRSPRPTAIFCGNDEMAAGVLQSARKAGLSVPQDLTVVGFDDFQIAQAVWPPLTTIHTP 316 Query: 291 ITEISELGTK 300 EI + + Sbjct: 317 TREIGRIAVE 326 >YPO0611 [K] COG1609 Transcriptional regulators Length = 328 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 107/332 (32%), Positives = 174/332 (52%), Gaps = 11/332 (3%) Query: 2 ITIKDIARVAGVSHTTVSRALNGSPLIKKVTRDKIEKIAAEMNYVPNYSAKSLVTKRSFT 61 +TIKD+A+ A VS +TVS A+NGSP I + TR ++ KIA EMNY N +AK L K+S Sbjct: 3 VTIKDVAKRAKVSISTVSYAINGSPKITEETRLRVLKIAQEMNYTANNNAKMLKAKKSGA 62 Query: 62 IGLFFSSIEQGTSASFLVDAIKGISHILDENFNLTVNGIDG-----VHNFGNIQPQRFDG 116 IGLFF+S G S LV I+ H E+++L + G H + ++ + DG Sbjct: 63 IGLFFNSW-FGPVYSELVRGIEERVH--REHYDLVACSLYGGEQSTAHKY--LRDRSVDG 117 Query: 117 ILVMSQSDEDNAFIYHVKKMGIPLVVLNRQLEDPGIMNVVANDREGVKEAIDYAVRQGHR 176 ++++ S +D F+ V +P+VVL+R+L+ P I NV+ ++ G +A++ + +G R Sbjct: 118 AIILTSSFDDR-FLQSVASDVLPIVVLDRELKSPHIYNVLIDNFGGAFKAVNALLAKGCR 176 Query: 177 KLAIIEGKPGFKSSSERKQGFMDSLIAHRLPLNSGYFAAGDYSIESGYAAMAALLQLEDP 236 + G + +R GF+ +L H + LN + +++ Y M AL+ Sbjct: 177 DIYFFSGPEQSYDNQKRLDGFIAALGYHNIQLNRDFIIHSNFTEADAYLKMQALIAAGRV 236 Query: 237 PTAVFCSNDDMAIGAMNACYAHKADVPGQISLLGFDDIMFSRYTNPALTTVRKPITEISE 296 P+A+F +ND+MAIG + A H VP + ++GFD+I S P+LTT+ E+ Sbjct: 237 PSAIFSANDEMAIGILRAAKEHNIRVPDDLKVVGFDNIYASSVLTPSLTTINHHKYEMGV 296 Query: 297 LGTKMXXXXXXXXXXXXXXXFVNTSLVIRQTV 328 + + T L+ R+T+ Sbjct: 297 ISANTLLRAIKEETNIDAVTLLPTELIERETL 328 >HI0506 [K] COG1609 Transcriptional regulators Length = 332 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 94/307 (30%), Positives = 159/307 (51%), Gaps = 14/307 (4%) Query: 1 MITIKDIARVAGVSHTTVSRALNGSPLIKKVTRDKIEKIAAEMNYVPNYSAKSLVTKRSF 60 M T+KDIAR+A VS +TVS +NGS + R+K+ +I AE+NY P+ A+SL + + Sbjct: 1 MATMKDIARLAQVSTSTVSHVINGSRFVSDEIREKVMRIVAELNYTPSAVARSLKVRETK 60 Query: 61 TIGLFFSSIEQGTSASFLVDAIKGISHILDEN-FNLTVNGIDG-----VHNFGNIQPQRF 114 TIGL ++ T+ F + + G+ +N +NL + G N + ++ Sbjct: 61 TIGLLVTA----TNNPFFAEVMAGVEQYCQKNQYNLIIATTGGDAKRLQQNLQTLMHKQV 116 Query: 115 DGILVMSQSDEDNAFIYHVK-KMGIPLVVLNRQLEDPGIMNVVANDREGVKEAIDYAVRQ 173 DG+L+M D+ F ++ + +PLVV++ + ++ N G A + Sbjct: 117 DGLLLMCG---DSRFQADIELAISLPLVVMDWWFTELNADKILENSALGGYLATKALIDA 173 Query: 174 GHRKLAIIEGKPGFKSSSERKQGFMDSLIAHRLPLNSGYFAAGDYSIESGYAAMAALLQL 233 GHRK+ II G + R QG+ ++L ++ LN + + E G + +LL Sbjct: 174 GHRKIGIITGNLKKSVAQNRLQGYKNALSEAKIALNPHWIVESHFDFEGGVLGIQSLLTQ 233 Query: 234 EDPPTAVFCSNDDMAIGAMNACYAHKADVPGQISLLGFDDIMFSRYTNPALTTVRKPITE 293 PTAVFC +D +A+GA A +P +S++G+DDI +RY +P L+T+ +P E Sbjct: 234 SSRPTAVFCCSDTIAVGAYQAIQQQGLRIPQDLSIMGYDDIELARYLSPPLSTICQPKAE 293 Query: 294 ISELGTK 300 + +L + Sbjct: 294 LGKLAVE 300 >SMb20014 [K] COG1609 Transcriptional regulators Length = 333 Score = 156 bits (395), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 100/297 (33%), Positives = 155/297 (52%), Gaps = 15/297 (5%) Query: 4 IKDIARVAGVSHTTVSRALNGSPLIKKVTRDKIEKIAAEMNYVPNYSAKSLVTKRSFTIG 63 IKDIA AGVS TVSRAL S L+ TR ++ +A E++Y PN SA++L T+RS T+ Sbjct: 7 IKDIAEKAGVSVATVSRALAASTLVTAETRQRVLDLARELDYRPNVSARNLRTRRSMTVL 66 Query: 64 LFFSSIEQGTSASFLVDAIKGISHILDENFNLTVNG------IDGVHNFGNIQPQRFDGI 117 + + F +D +KG+ E + G F ++ DG+ Sbjct: 67 MVVRDVGN----PFYLDILKGVEATAREAGYAVLMGNTENDPARETEYFSMLRDGHADGM 122 Query: 118 LVMSQSDEDNAFIYHVKKMGIPLVVLNRQLEDPGIMNVVANDREGVKEAIDYAVRQGHRK 177 ++M+ H +P+VV +E G+ +V ++ + A+ + + GHR+ Sbjct: 123 ILMTGKLPSAGDWNH-----LPVVVALEMIEGSGLPHVQVDNVAAARGAVQHLISLGHRR 177 Query: 178 LAIIEGKPGFKSSSERKQGFMDSLIAHRLPLNSGYFAAGDYSIESGYAAMAALLQLEDPP 237 +A I G S R++GF ++ L + +GY GD+ IESG +L L DPP Sbjct: 178 IAHISGPVPEPMSVYRREGFRLAMRDAGLTIPAGYEVRGDFLIESGEECCRSLFSLSDPP 237 Query: 238 TAVFCSNDDMAIGAMNACYAHKADVPGQISLLGFDDIMFSRYTNPALTTVRKPITEI 294 TA+F +ND+MA GA++ DVPG +S++GFDD+ S+ P LTTV +P +EI Sbjct: 238 TALFVANDEMAYGAVHELRRIGRDVPGDVSVVGFDDLYLSKAFYPPLTTVGQPRSEI 294 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.135 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 21,924,913 Number of extensions: 867701 Number of successful extensions: 2218 Number of sequences better than 1.0e-05: 179 Number of HSP's gapped: 2003 Number of HSP's successfully gapped: 185 Length of query: 331 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 224 Effective length of database: 26,037,693 Effective search space: 5832443232 Effective search space used: 5832443232 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)