BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0345.0015.p (430 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yqjH [L] COG0389 Nucleotidyltransferase/DNA polymerase involv... 353 2e-97 BH1472 [L] COG0389 Nucleotidyltransferase/DNA polymerase involve... 342 6e-94 BS_yqjW [L] COG0389 Nucleotidyltransferase/DNA polymerase involv... 244 2e-64 BMEII0656 [L] COG0389 Nucleotidyltransferase/DNA polymerase invo... 232 9e-61 CC2466 [L] COG0389 Nucleotidyltransferase/DNA polymerase involve... 214 2e-55 >BS_yqjH [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Length = 673 Score = 353 bits (907), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 28/413 (6%), Positives = 82/413 (19%), Gaps = 9/413 (2%) Query: 9 PASGRVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGIST 68 + V+ C V T + G A + Sbjct: 2 RLNPGQQQAVEFVTGPCLVLAGAGS-GKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60 Query: 69 GMQVQKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSRQF 128 ++ + + ++ Y+ + S+ + + ++ Sbjct: 61 REMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKEL 120 Query: 129 GTPLEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILWDK 188 L + + + + + A A + L D + Sbjct: 121 TEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNV 180 Query: 189 PCNEMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVVNP 248 + + + + + L + G Sbjct: 181 LDFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVV 240 Query: 249 ER-EQSKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPDMK 307 +QS + V+ + + + +Q R + A+ + K Sbjct: 241 GDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEK 300 Query: 308 TITRSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLDLFN 367 + + + + + + Q +F Sbjct: 301 RLFSELGYGAELKVLSANNEEHEAERVTGELIA-HHFVNKTQYKDYAILYRGNHQSRVFE 359 Query: 368 YERQPKKESLNKAMDMLRNKFGENAVLTAGMLSDSHSARLRNHKERGTSLQKD 420 + + E L A + ++ + L+ Sbjct: 360 KFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNP------DDDSAFLRIV 406 >BH1472 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Length = 673 Score = 342 bits (878), Expect = 6e-94, Method: Compositional matrix adjust. Identities = 25/410 (6%), Positives = 71/410 (17%), Gaps = 6/410 (1%) Query: 12 GRVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGISTGMQ 71 + A K + + +R AA + Sbjct: 4 NPGQQQAVEFVTGPCLVLAGAG-SGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAARE 62 Query: 72 VQKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSRQFGTP 131 +++ + + + ++A D + T Sbjct: 63 MKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTE 122 Query: 132 LEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILWDKPCN 191 I + + A ++ ++ + + + Sbjct: 123 GLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLD 182 Query: 192 EMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVVNPERE 251 I T + Q + + + Sbjct: 183 FDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGD 242 Query: 252 -QSKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPDMKTIT 310 P ++V L++ P L + + R + L A+ + + + Sbjct: 243 DDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRL 302 Query: 311 RSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLDLFNYER 370 S + + + T A + Sbjct: 303 FSELGYGAELKVLSANNEEHEAERVTGEL-IAHHFVNKTQYKDYAILYRGNHQSRVFEKF 361 Query: 371 QPKKESLNKAMDMLRNKFGENAVLTAGMLSDSHSARLRNHKERGTSLQKD 420 + K + + + Sbjct: 362 LMQNRIPYKISGGTSFFSRPEIKDLL---AYLRVLTNPDDDSAFLRIVNT 408 >BS_yqjW [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Length = 673 Score = 244 bits (623), Expect = 2e-64, Method: Compositional matrix adjust. Identities = 29/411 (7%), Positives = 77/411 (18%), Gaps = 15/411 (3%) Query: 13 RVILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGISTGMQV 72 + A K + + +R AA ++ Sbjct: 5 PGQQQAVEFVTGPCLVLAGAG-SGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREM 63 Query: 73 QKALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSRQ-FGTP 131 ++ + + + ++A D + Sbjct: 64 KERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELTEG 123 Query: 132 LEIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASD---LKKPNGISILRLRDVPDILWDK 188 L + + + + + A A + + + D Sbjct: 124 LIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVLDF 183 Query: 189 PCNEMFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVVNP 248 + A + + + + DE L V + Sbjct: 184 DDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVGDD 243 Query: 249 ER-EQSKSIGHTTTLPSDVVGL-AEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPDM 306 ++ S L A L R L+ ++ + Sbjct: 244 DQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKRLF 303 Query: 307 KTIT---RSRQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQL 363 + + L E E T + + +G + Sbjct: 304 SELGYGAELKVLSANNEEHEAERVTGELIAHHFVNK-TQYKDYAILYRGNHQ--SRVFEK 360 Query: 364 DLFNYERQPKKESLNKAMDMLRNKFGENAVLTAGMLSDSHSARLRNHKERG 414 L + + + R + + + + + Sbjct: 361 FLM--QNRIPYKISGGTSFFSRPEIKDLLAYLRVLTNPDDDSAFLRIVNTP 409 >BMEII0656 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Length = 673 Score = 232 bits (591), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 17/401 (4%), Positives = 67/401 (16%), Gaps = 10/401 (2%) Query: 15 ILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGISTGMQVQK 74 + + E G T + + Sbjct: 49 HIAAVTFTNKAAREMKERVG-QTLGRKEARGL---MISTFHTLGLDIIKREYAALGMKAN 104 Query: 75 ALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSRQF--GTPL 132 + L + + + + + + + S Sbjct: 105 FSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIF 164 Query: 133 EIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILWDKPCNE 192 G+ ++ + + L A++ + + +R V + Sbjct: 165 AHCYGLYDAHLKACNVLDFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQY 224 Query: 193 MFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVVNPEREQ 252 + + + + + + ++ + R Sbjct: 225 ELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRIL 284 Query: 253 SKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPDMKTITRS 312 K+ V + +V ++ I + Sbjct: 285 -KAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELIAHHFVNKTQYK 343 Query: 313 RQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDSAIQLDLFNYERQP 372 + + R + + + +++ + Sbjct: 344 DYAILYRGNHQSRVFEKFLMQNRIPYKIS-GGTSFFSRPEIKD-LLAYLRVLTNPDD-DS 400 Query: 373 KKESLNKAMDMLRNKFGENAVLTAGMLSDSHSARLRNHKER 413 + + M + Sbjct: 401 AFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGL 441 >CC2466 [L] COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair Length = 673 Score = 214 bits (545), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 19/388 (4%), Positives = 55/388 (14%), Gaps = 13/388 (3%) Query: 15 ILHVDMNAFYCSVHEAEDPDQYKGKATAVAGSVELRRGIIVTCSYAARRLGISTGMQVQK 74 L + + + + G+ + K Sbjct: 38 HLIRGCGYQARHIAAVTFT-NKAAREMKERVG---QTLGRKEARGLMISTFHTLGLDIIK 93 Query: 75 ALRICPSLLLIKPDFHLYRKYSNAFMQIAYSYTPLLEAVSIDECYLDITGSRQF--GTPL 132 + F + + + + + Sbjct: 94 REYAALGMKANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAA 153 Query: 133 EIAEGIQRRIMEELGLPCSIGIAPNKLLAKIASDLKKPNGISILRLRDVPDILWDKPCNE 192 A G + RI + +L L + + Sbjct: 154 ASAIGERDRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQANEEVRKRWQNKIRYLLV 213 Query: 193 MFGIGGKTAEKLRKLGIYSIGQLAAADERMLVEHFGVMGSWLKRAGNGIDHGVVNPEREQ 252 T++ + + G+ + + Sbjct: 214 DEYQDTNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKL 273 Query: 253 SKSIGHTTTLPSDVVGLAEARPVLLNLSDQVARRLRKQGLVASGVQLTIRTPDMKTITRS 312 + ++ + A + + L + T Sbjct: 274 -EQNYRSSGRILKAANILIANNPHVFEKRLFSELGYGAELKVLSANNEEHEAERVTGELI 332 Query: 313 RQLETPTESAEDIYKTACDQFARHWKGDKPVRLLGVTLQGLTAKEDS-AIQLDLFNYERQ 371 +D K + + + Sbjct: 333 AHHFVNKTQYKDYAILYRGNHQSRVFE-KFLMQNRI---PYKISGGTSFFSRPEIKDLLA 388 Query: 372 PKKESLNKAMDMLRNKFGENAVLTAGML 399 + D N Sbjct: 389 YLRVL-TNPDDDSAFLRIVNTPKREIGP 415 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.135 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 31,448,871 Number of extensions: 1290811 Number of successful extensions: 9750 Number of sequences better than 1.0e-05: 45 Number of HSP's gapped: 9605 Number of HSP's successfully gapped: 45 Length of query: 430 Length of database: 38,378,431 Length adjustment: 109 Effective length of query: 321 Effective length of database: 25,807,025 Effective search space: 8284055025 Effective search space used: 8284055025 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 117 (49.7 bits)