BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0043.p (336 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEI0019 [K] COG1609 Transcriptional regulators 216 5e-56 BMEII0312 [K] COG1609 Transcriptional regulators 200 3e-51 TM1200 [K] COG1609 Transcriptional regulators 182 5e-46 SMa0078 [K] COG1609 Transcriptional regulators 179 5e-45 PM0547 [K] COG1609 Transcriptional regulators 155 1e-37 >BMEI0019 [K] COG1609 Transcriptional regulators Length = 372 Score = 216 bits (550), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 113/303 (37%), Positives = 177/303 (58%), Gaps = 1/303 (0%) Query: 1 VADDAGVSRATASLVVRGSKSIKPSTHKKVMDSIEKLGYVYDRVAASFRSQSSSTVGIVI 60 +A +AGVS++T SLV+R S + T KV ++IEKLGYVY+R AA+ R S +G+V+ Sbjct: 31 IAREAGVSKSTVSLVLRDSPLVHAETRAKVQEAIEKLGYVYNRSAANLRQAKSKIIGLVV 90 Query: 61 TDFENPFYHQMLTKVEDMLYEQQFTFLLGMSSESREKQERVLETMLEHRVCGIILTPVVD 120 D N F+ ++ V+ ++ + L ++ES ++Q V+ +M EH + G+I++P Sbjct: 91 NDLTNSFFAELAVGVDRVMQSAGYVQFLANTAESIDRQREVIASMREHGIAGLIVSPARG 150 Query: 121 TQPTLFNKLRALQIPALLMGREVAGSGADYVGTDYRLGSQLAVRHLVEQGHRRIAYIGGM 180 T+ + L +P + M R+V GSG + +D R G AV HLV GHR IA++GG Sbjct: 151 TEASDLKPLAKSGLPVVQMVRDVPGSGVSSIVSDNRGGVAKAVEHLVSLGHRAIAFMGG- 209 Query: 181 LPGNTAYQERIDGYCSALQEYGLEVDPKLIMPTPLNREGGIRAIQEVLKLENPPTACFCH 240 + ER+ GY + L++ G+ D L+ + +R GG+ A++++L+ PTA C Sbjct: 210 YADIAVFSERLAGYRTGLEQAGIAFDEALVFTSAPSRAGGVEALEQMLRQGMKPTAAVCF 269 Query: 241 NDIIALGVTIGLRLQGLIPGEHMAIVGFDNILETETVEPKLTTVSVFHDQWGVEAARQIL 300 ND +A GV GLR L PG +VGFD+++E +T P LTTV+V G AA+ +L Sbjct: 270 NDAVAFGVCDGLRATHLEPGRDFGVVGFDDVIEAKTAVPALTTVAVDPQGLGERAAQLLL 329 Query: 301 DRI 303 +I Sbjct: 330 KQI 332 >BMEII0312 [K] COG1609 Transcriptional regulators Length = 358 Score = 200 bits (508), Expect = 3e-51, Method: Compositional matrix adjust. Identities = 108/307 (35%), Positives = 169/307 (55%), Gaps = 1/307 (0%) Query: 1 VADDAGVSRATASLVVRGSKSIKPSTHKKVMDSIEKLGYVYDRVAASFRSQSSSTVGIVI 60 +AD GVS AT SL +R S + T +K+ + +GY+Y+R AAS R+ S VG+V+ Sbjct: 29 IADALGVSTATVSLALRDSPLVADQTREKIKEHARAIGYIYNRRAASLRTSRSGIVGVVV 88 Query: 61 TDFENPFYHQMLTKVEDMLYEQQFTFLLGMSSESREKQERVLETMLEHRVCGIILTPVVD 120 D NPF+ ++L +E L + TF+L + +KQ ++T+L+ G+I++P + Sbjct: 89 RDIMNPFFAEILKSIETELDRSRQTFILSNHYDQLDKQRTFMDTLLQLGADGVIMSPAIG 148 Query: 121 TQPTLFNKLRALQIPALLMGREVAGSGADYVGTDYRLGSQLAVRHLVEQGHRRIAYIGGM 180 T +P +L+ R V G A D G LA HL+ GH RIA IGG Sbjct: 149 TPAEDIQLAEDNGLPVVLIARSVEGVHAPVFRGDNAYGIGLATNHLISLGHTRIAMIGGT 208 Query: 181 LPGNTAYQERIDGYCSALQEYGLEVDPKLIMPTPLNREGGIRAIQEVLKLENPPTACFCH 240 +T ++R GY A+++ GLEV P +P P ++GG + L L++ PTA C Sbjct: 209 DQTSTG-RDRYRGYVQAMEKAGLEVRPDWRIPGPRTKQGGFEVAPQFLALKDKPTAAVCW 267 Query: 241 NDIIALGVTIGLRLQGLIPGEHMAIVGFDNILETETVEPKLTTVSVFHDQWGVEAARQIL 300 ND+ A+G+ G+ GL+PGE +++ G+D++ E P LTTV + G AAR +L Sbjct: 268 NDLTAIGLMNGIARAGLVPGEDISVTGYDDLEEAAIATPALTTVWNGQREVGRRAARALL 327 Query: 301 DRIGGLQ 307 D++ G++ Sbjct: 328 DQLNGVE 334 >TM1200 [K] COG1609 Transcriptional regulators Length = 333 Score = 182 bits (463), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 102/300 (34%), Positives = 170/300 (56%), Gaps = 2/300 (0%) Query: 1 VADDAGVSRATASLVVRGSKSIKPSTHKKVMDSIEKLGYVYDRVAASFRSQSSSTVGIVI 60 +A+ AGVS T S + I T +K++ ++LGYV + A+S RS+ ++ VG++I Sbjct: 11 IAEKAGVSINTVSRALNNKPDISEETRRKILKIAQELGYVKNATASSLRSKQTNIVGVII 70 Query: 61 TDFENPFYHQMLTKVEDMLYEQQFTFLLGMSSESREKQERVLETMLEHRVCGIILTPVVD 120 D NPFY ++L +E + + +L + E +E+ +E +L+ RV G+++TPV D Sbjct: 71 ADSANPFYAEVLKGIEAASRKYGYQIMLMNTERIYENEEKAIEVLLQRRVDGLLITPVQD 130 Query: 121 TQPTLFNKLRALQIPALLMGREVAGSGADYVGTDYRLGSQLAVRHLVEQGHRRIAYIGGM 180 + L ++P +++GR D + +D G LA RHL+E+G + I I G Sbjct: 131 RSDDI-KTLIERKVPFVIVGRHFEELEVDEIHSDEVKGGYLATRHLIERGRKNIIMISGY 189 Query: 181 LPGNTAYQERIDGYCSALQEYGLEVDPKLIMPTPLNREGGIRAIQEVLKLENPPTACFCH 240 L + AY R++GY AL+EYG+ K+I+ T ++ E G RA++E ++ A FC+ Sbjct: 190 LFKSAAYM-RLEGYRKALKEYGIPFSEKMIIETDIDIESGYRAMREAIEKGLEFEAVFCY 248 Query: 241 NDIIALGVTIGLRLQGLIPGEHMAIVGFDNILETETVEPKLTTVSVFHDQWGVEAARQIL 300 ND++A GV L+ G E +A+VG+D+I+ + + P LTTV + + G EA R +L Sbjct: 249 NDLLAFGVIKALKECGYRIPEDVAVVGYDDIVYSSFICPSLTTVRIKKFEMGFEAFRMLL 308 >SMa0078 [K] COG1609 Transcriptional regulators Length = 340 Score = 179 bits (455), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 105/305 (34%), Positives = 169/305 (55%), Gaps = 6/305 (1%) Query: 1 VADDAGVSRATASLVVRGSKSIKPSTHKKVMDSIEKLGYVYDRVAASFRSQSSSTVGIVI 60 VA A VSRATASLV+R S + T +V ++ LGYVY+ AA R + S +G ++ Sbjct: 16 VARHASVSRATASLVLRKSPLVGSETRARVEQAMRDLGYVYNIGAARLRVERSQIIGAIV 75 Query: 61 TDFENPFYHQMLTKVEDMLYEQQFTFLLGMSSESREKQERVLETMLEHRVCGIILTPVVD 120 + NPF+ ++L+ +E+ + +L S E E+Q +L+ M EH V G++L P Sbjct: 76 PNLTNPFFAELLSGIEEAIGATGKVVILANSGERVERQSMLLQRMREHGVDGVVLCPAAG 135 Query: 121 TQPTLFNKLRALQIPALLMGREVAGSGADYVGTDYRLGSQLAVRHLVEQGHRRIAY-IGG 179 T+P L +L A +P + + R ++ DYVG DY G + AV +L GH +IA+ + G Sbjct: 136 TEPDLSEQLAAWGMPVVQVLRHIS-VDMDYVGVDYAGGMRQAVDYLASLGHEKIAFAVHG 194 Query: 180 MLPGNTAYQERIDGYCSALQEYGLEVDPKLIMPTPLNREGGIRAIQEVLKLENPPTACFC 239 P ++AY+ER+DG+ A+ DP++++ P + + PTA C Sbjct: 195 --PFHSAYRERVDGFRDAMLAKAF--DPEILIHLPAQLGEIADSTHLLFAKATQPTAVIC 250 Query: 240 HNDIIALGVTIGLRLQGLIPGEHMAIVGFDNILETETVEPKLTTVSVFHDQWGVEAARQI 299 N ++ALG+ GL GL G ++++GFD++ + E + P+LT+VS G AAR + Sbjct: 251 FNHLVALGLAAGLHDCGLTIGRDLSLIGFDDVADAEAIRPRLTSVSTGPTAIGEMAARLL 310 Query: 300 LDRIG 304 ++RI Sbjct: 311 VERIA 315 >PM0547 [K] COG1609 Transcriptional regulators Length = 334 Score = 155 bits (391), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 90/304 (29%), Positives = 157/304 (51%), Gaps = 1/304 (0%) Query: 1 VADDAGVSRATASLVVRGSKSIKPSTHKKVMDSIEKLGYVYDRVAASFRSQSSSTVGIVI 60 VA AGVS T S V+ ++ + T K V+ +I++L Y VA S + ++ ++G+++ Sbjct: 7 VAKMAGVSTTTVSHVINKTRFVAAETEKLVLQAIQELNYSPSAVARSLKVNTTKSIGMIV 66 Query: 61 TDFENPFYHQMLTKVEDMLYEQQFTFLLGMSSESREKQERVLETMLEHRVCGIILTPVVD 120 T E P++ +++ VE+ Y Q ++ L + + EK + LE +++ RV GI++ Sbjct: 67 TSSEAPYFAEIIHAVEEHCYRQGYSLFLCNTQNNVEKIKNHLEMLIKKRVDGILVMCAEY 126 Query: 121 TQPTLFNKLRALQIPALLMGREVAGSGADYVGTDYRLGSQLAVRHLVEQGHRRIAYIGGM 180 TQ +L +P ++M D + G LA ++L++ GH+ I I G Sbjct: 127 TQDSLDLLANFTSLPLVVMDWGPDNKHTDIIQDHSFEGGYLATKYLIDHGHKDIGIIAGE 186 Query: 181 LPGNTAYQERIDGYCSALQEYGLEVDPKLIMPTPLNREGGIRAIQEVLKLENPPTACFCH 240 L TA + R +G+ A+ E GL+++P +M E G + ++L + PTA FC Sbjct: 187 LTKTTA-KTRYEGFIKAMNEAGLKINPDWVMEGFFEPEDGYECMNKILAQDTLPTAVFCC 245 Query: 241 NDIIALGVTIGLRLQGLIPGEHMAIVGFDNILETETVEPKLTTVSVFHDQWGVEAARQIL 300 ND++ALG + +GL E ++I+G+DNI + P LTT+ + G A + Sbjct: 246 NDVMALGAISAIGEKGLRVPEDISIIGYDNIHASRFYSPPLTTIHQSKSRLGARAVTLLF 305 Query: 301 DRIG 304 +RI Sbjct: 306 ERIN 309 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.320 0.137 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,144,190 Number of extensions: 944094 Number of successful extensions: 2164 Number of sequences better than 1.0e-05: 171 Number of HSP's gapped: 1916 Number of HSP's successfully gapped: 171 Length of query: 336 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 229 Effective length of database: 26,037,693 Effective search space: 5962631697 Effective search space used: 5962631697 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)