BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0032.p (591 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0155 [V] COG1132 ABC-type multidrug transport system, ATPase ... 639 0.0 BS_yknV [V] COG1132 ABC-type multidrug transport system, ATPase ... 437 e-122 BH1126 [V] COG1132 ABC-type multidrug transport system, ATPase a... 435 e-122 TM0288 [V] COG1132 ABC-type multidrug transport system, ATPase a... 392 e-109 BS_yfiC [V] COG1132 ABC-type multidrug transport system, ATPase ... 366 e-101 >lin0155 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 593 Score = 639 bits (1648), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/587 (52%), Positives = 412/587 (70%), Gaps = 1/587 (0%) Query: 1 MARNKFDVDENLESPFDIRHFRRAMIYIKRKKKPMXXXXXXXXXXXXXXXXXXXXMQHVV 60 MARNKFD+DE LE+ F H +R ++Y+K +K + + V+ Sbjct: 1 MARNKFDIDEELETAFSAAHLKRILVYVKPYQKSIYITLFVILLANVATMIGPYLTKVVI 60 Query: 61 DVTIPSKEKXXXXXXXXXXXXTIVVSVILATIRSRIMTRVGQDIIFDIRTDLFAHLQQLP 120 D TIP+K +++V+ + R R +T +GQDI+ D+RT +F HLQ+LP Sbjct: 61 DETIPNKNMTQLFWIAVIFIVSVIVTGLCMRYRIRSITLIGQDILKDMRTAIFGHLQKLP 120 Query: 121 FKYYDDRPQGKILIRVVNYVNSVSDVLSNGIINFILEIVNLIFIAAFMFAVDVRLSFVIL 180 F Y+D RP GKILIRVVNY+N +SD+LSNG+IN I +I+++I FM +D L+ L Sbjct: 121 FSYFDSRPHGKILIRVVNYINMLSDLLSNGLINLISDILSVIVTLGFMLMIDPVLTLYSL 180 Query: 181 AGLPVFLGIMLLIKTRQRRAWQAVSNKSSNLNAYMQESITGIGVTQIFSREQQNAGIFTR 240 A +PV I+++IKT QR+A+Q +SNK SN+NAY+ ESI GI VTQ FSRE++N IFT Sbjct: 181 ALIPVLFVIVMVIKTAQRKAYQVLSNKQSNMNAYIHESIAGIKVTQSFSREEENFEIFTE 240 Query: 241 LAGNFRKEWMRAVSYNMLIPFSVDNLSTIVTALIFLVGLLTLDPVDATLGVILAMSSYAA 300 ++ +R+ WM+AV L+ V N++ + T LI+ VG+ VD + G ++A Y Sbjct: 241 VSNEYRRSWMKAVKIQFLLWPGVQNIAVMTTCLIYFVGIKGYG-VDVSTGTLIAFIGYVG 299 Query: 301 RFWQPILNLSNLYNSFINAVAYLERIFETLDEPVTVSDIPDARELPSVQGRVTFDHVTFA 360 FW P++N+ N YNS I A YLERIFET+D + D+P+A+++P + G V F V F Sbjct: 300 NFWNPVINIGNFYNSLITATTYLERIFETMDVEPDIKDVPNAKKMPPIVGNVDFKDVYFR 359 Query: 361 YDPGLNILENISFDVQPGESIALVGPTGAGKTTVVNLISRFYDLTGGRILIDGQDISQIT 420 Y+ G++IL+ I+F V GESIALVGPTGAGKTT++NL+SRFY++ G IL+DG+++ ++T Sbjct: 360 YEEGVDILKGINFHVDAGESIALVGPTGAGKTTIINLLSRFYNINSGEILVDGENVEEVT 419 Query: 421 LKSLRSQMGIMLQDSFIFSGTILDNIRYGKLDATEEEVIAAAKAVCADDFIREFDQGYLT 480 L+SLRSQMG+MLQD+FIFSGTI++NIRYGKLDATEEE+IAAAK V A DFI GY T Sbjct: 420 LRSLRSQMGVMLQDTFIFSGTIIENIRYGKLDATEEEIIAAAKVVRAHDFISGLKDGYYT 479 Query: 481 EVNERGSKLSQGQRQLISFARTLLADPRILILDEATSSIDAKTERLLQKGLNELLKGRTS 540 EV ERGS LS GQRQLISFAR LLADP+ILILDEATSSID +TE LLQ+GL LL+GRTS Sbjct: 480 EVKERGSTLSAGQRQLISFARALLADPKILILDEATSSIDTQTEILLQEGLERLLEGRTS 539 Query: 541 FIIAHRLSTVKNCDRIMYVSNKGIAESGSHDELIARRGLYHKLYTAQ 587 FIIAHRLST+KN RI Y+ N I E+GSH+EL+A+ G Y+ LY +Q Sbjct: 540 FIIAHRLSTIKNSSRIFYIDNGRIQEAGSHEELMAQHGYYYNLYQSQ 586 >BS_yknV [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 604 Score = 437 bits (1125), Expect = e-122, Method: Compositional matrix adjust. Identities = 232/589 (39%), Positives = 353/589 (59%), Gaps = 2/589 (0%) Query: 1 MARNKFDVDENLESPFDIRHFRRAMIYIKRKKKPMXXXXXXXXXXXXXXXXXXXXM--QH 58 + R + DE +E PF+ R + Y+K +K + + + Sbjct: 10 LERFYYSSDEIIEKPFNWAQMWRLLSYVKPYRKTILPLSFLTVLIGTAVKLVIPILIGVY 69 Query: 59 VVDVTIPSKEKXXXXXXXXXXXXTIVVSVILATIRSRIMTRVGQDIIFDIRTDLFAHLQQ 118 V+D I + V++ +R R M ++GQ +I+D+R LF H+Q+ Sbjct: 70 VLDQAITGRNSELLIQLIFIISGLYVLNYAANVLRIRWMNQLGQHVIYDLRQHLFTHVQR 129 Query: 119 LPFKYYDDRPQGKILIRVVNYVNSVSDVLSNGIINFILEIVNLIFIAAFMFAVDVRLSFV 178 L +++D R G IL+R++N +NS+ ++ ++G+IN + +++ L + +F + L+ Sbjct: 130 LSHRFFDQRSAGSILVRIMNDINSLQELFTSGVINLLTDLLLLAGVIIILFTLSPELTIA 189 Query: 179 ILAGLPVFLGIMLLIKTRQRRAWQAVSNKSSNLNAYMQESITGIGVTQIFSREQQNAGIF 238 I+ LP+ I ++ + RR+WQ V K S LN+++ ESI GI VTQ F++E++N F Sbjct: 190 IMVTLPIMFFISTSLRKKIRRSWQTVRLKQSKLNSHLNESIQGIRVTQAFTQEEENMAYF 249 Query: 239 TRLAGNFRKEWMRAVSYNMLIPFSVDNLSTIVTALIFLVGLLTLDPVDATLGVILAMSSY 298 + + W A N + V+ + I TA++ G + T+GV ++ + Y Sbjct: 250 DGVNQENYESWREATRKNAMFRPLVEMTNAIGTAVLIWYGATLIMNETITIGVFVSFAFY 309 Query: 299 AARFWQPILNLSNLYNSFINAVAYLERIFETLDEPVTVSDIPDARELPSVQGRVTFDHVT 358 FW+PI L +YN + +A ERIFE LDE V + P+A + G ++F+ V Sbjct: 310 LGMFWEPISRLGQVYNQLLMGMASSERIFEFLDEQPNVKEKPNAIHNEKINGEISFEEVE 369 Query: 359 FAYDPGLNILENISFDVQPGESIALVGPTGAGKTTVVNLISRFYDLTGGRILIDGQDISQ 418 F+YD L +SF + G ++ALVG TG+GKTT+ NLISRFYD GG I IDG I Sbjct: 370 FSYDEKRKALHAVSFSIPAGSTLALVGHTGSGKTTIANLISRFYDAAGGTIKIDGIPIKD 429 Query: 419 ITLKSLRSQMGIMLQDSFIFSGTILDNIRYGKLDATEEEVIAAAKAVCADDFIREFDQGY 478 ++L SLRSQ+ I+LQD+FIFSGTI++NIR+G+ +A++EEV+ A++AV AD+FI + +GY Sbjct: 430 LSLASLRSQISIVLQDTFIFSGTIMENIRFGRPNASDEEVMKASQAVGADEFISDLAEGY 489 Query: 479 LTEVNERGSKLSQGQRQLISFARTLLADPRILILDEATSSIDAKTERLLQKGLNELLKGR 538 TEV ERGS LS GQRQLISFAR LLADP I+ILDEAT+SID +TE +Q+ L LLKGR Sbjct: 490 ATEVEERGSVLSAGQRQLISFARALLADPAIIILDEATASIDTETEVKIQQALKTLLKGR 549 Query: 539 TSFIIAHRLSTVKNCDRIMYVSNKGIAESGSHDELIARRGLYHKLYTAQ 587 T+ +IAHRLST+++ DRI+ + + E G+HD+L+A+ G+Y L AQ Sbjct: 550 TAVMIAHRLSTIRDADRIIVLDHGRKIEEGNHDQLLAKGGIYAGLVKAQ 598 >BH1126 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 601 Score = 435 bits (1119), Expect = e-122, Method: Compositional matrix adjust. Identities = 229/503 (45%), Positives = 329/503 (65%) Query: 85 VSVILATIRSRIMTRVGQDIIFDIRTDLFAHLQQLPFKYYDDRPQGKILIRVVNYVNSVS 144 +S + R R M +GQ +I+DIR DLF H+Q+L +++D R G IL+RVVN VNS+ Sbjct: 93 ISYVANVFRIRWMNEIGQHVIYDIRADLFNHIQRLSHRFFDQRSAGSILVRVVNDVNSLQ 152 Query: 145 DVLSNGIINFILEIVNLIFIAAFMFAVDVRLSFVILAGLPVFLGIMLLIKTRQRRAWQAV 204 D+ +NG+IN +++IV L+ I +F++ L+ +IL LP+ I ++ RR+WQ V Sbjct: 153 DLFTNGVINLLMDIVILLGIIVILFSLSPELAILILIVLPIMFFISTKLRRNIRRSWQTV 212 Query: 205 SNKSSNLNAYMQESITGIGVTQIFSREQQNAGIFTRLAGNFRKEWMRAVSYNMLIPFSVD 264 + S LN+++ ESI GI VTQ FS+E++N F + + W A N L V+ Sbjct: 213 RLRQSKLNSHLNESIQGIRVTQAFSQEKENMRFFRDINEENFQSWKDATRMNALFRPFVE 272 Query: 265 NLSTIVTALIFLVGLLTLDPVDATLGVILAMSSYAARFWQPILNLSNLYNSFINAVAYLE 324 S I ++ G+ + T+GV ++ + Y FW+PI L +YN + +A E Sbjct: 273 MASAIGAVVLIWYGVSLIQSEVLTVGVFVSFAFYLGMFWEPISRLGQVYNQLLVGMASSE 332 Query: 325 RIFETLDEPVTVSDIPDARELPSVQGRVTFDHVTFAYDPGLNILENISFDVQPGESIALV 384 RIFE LDE +V + +A L ++G VTF+ V F+YD L +ISF+++ G++IALV Sbjct: 333 RIFEFLDEKPSVPEKENAVTLHEMRGHVTFEQVEFSYDDKRKALNDISFEIKAGQTIALV 392 Query: 385 GPTGAGKTTVVNLISRFYDLTGGRILIDGQDISQITLKSLRSQMGIMLQDSFIFSGTILD 444 G TG+GK+T+VNLISRFYD T G I IDG D+ I L SLR+ + +LQD+FIF+GTI++ Sbjct: 393 GHTGSGKSTIVNLISRFYDPTAGVIKIDGVDLRDIQLNSLRTNVSFVLQDTFIFAGTIME 452 Query: 445 NIRYGKLDATEEEVIAAAKAVCADDFIREFDQGYLTEVNERGSKLSQGQRQLISFARTLL 504 NIR+G+ AT+EEV AAA+A+ A+DFI GY TEV E+G+ LS G+RQL+SFAR LL Sbjct: 453 NIRFGRPTATDEEVKAAAEAIGANDFIERLPNGYDTEVEEKGNVLSVGERQLLSFARALL 512 Query: 505 ADPRILILDEATSSIDAKTERLLQKGLNELLKGRTSFIIAHRLSTVKNCDRIMYVSNKGI 564 ADP+ILILDEAT+SID +TE +Q GL +LL RT+ +IAHRLST+++ D+I+ + I Sbjct: 513 ADPKILILDEATASIDTETELKIQAGLKKLLHDRTAIMIAHRLSTIRDADQIIVLEQGDI 572 Query: 565 AESGSHDELIARRGLYHKLYTAQ 587 E G+H EL+ RG Y+ L AQ Sbjct: 573 IEQGTHSELMDARGTYYGLVKAQ 595 >TM0288 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 598 Score = 392 bits (1008), Expect = e-109, Method: Compositional matrix adjust. Identities = 208/504 (41%), Positives = 327/504 (64%), Gaps = 3/504 (0%) Query: 85 VSVILATIRSRIMTRVGQDIIFDIRTDLFAHLQQLPFKYYDDRPQGKILIRVVNYVNSVS 144 ++ +L ++ +IM + QD++F +R +LF LQ++P ++D P G I+ RV+N V++++ Sbjct: 89 LTSLLFWLQGKIMLTLSQDVVFRLRKELFEKLQRVPVGFFDRTPHGDIISRVINDVDNIN 148 Query: 145 DVLSNGIINFILEIVNLIFIAAFMFAVDVRLSFVILAGLPVFLGIMLLIKTRQRRAWQAV 204 +VL N II F IV L MF V+V LS V L+ +P+ + I ++ ++ R+ + Sbjct: 149 NVLGNSIIQFFSGIVTLAGAVIMMFRVNVILSLVTLSIVPLTVLITQIVSSQTRKYFYEN 208 Query: 205 SNKSSNLNAYMQESITGIGVTQIFSREQQNAGIFTRLAGNFRKEWMRAVSYNMLIPFSVD 264 LN ++E I+G+ V ++F+RE++ F R+ + RK +A ++ ++P ++ Sbjct: 209 QRVLGQLNGIIEEDISGLTVIKLFTREEKEMEKFDRVNESLRKVGTKAQIFSGVLPPLMN 268 Query: 265 NLSTIVTALIF-LVGLLTLDPVDATLGVILAMSSYAARFWQPILNLSNLYNSFINAVAYL 323 ++ + ALI G L L + T+G I Y+ +F +P+ LSN +N A+A Sbjct: 269 MVNNLGFALISGFGGWLALKDI-ITVGTIATFIGYSRQFTRPLNELSNQFNMIQMALASA 327 Query: 324 ERIFETLDEPVTVSDIPDARELPSVQGRVTFDHVTFAYDPGLNILENISFDVQPGESIAL 383 ERIFE LD D PDA EL V+G + F +V F+YD +L++I+F ++PG+ +AL Sbjct: 328 ERIFEILDLEEEKDD-PDAVELREVRGEIEFKNVWFSYDKKKPVLKDITFHIKPGQKVAL 386 Query: 384 VGPTGAGKTTVVNLISRFYDLTGGRILIDGQDISQITLKSLRSQMGIMLQDSFIFSGTIL 443 VGPTG+GKTT+VNL+ RFYD+ G+IL+DG DI +I SLRS +GI+LQD+ +FS T+ Sbjct: 387 VGPTGSGKTTIVNLLMRFYDVDRGQILVDGIDIRKIKRSSLRSSIGIVLQDTILFSTTVK 446 Query: 444 DNIRYGKLDATEEEVIAAAKAVCADDFIREFDQGYLTEVNERGSKLSQGQRQLISFARTL 503 +N++YG AT+EE+ AAK +D FI+ +GY T + + G LSQGQRQL++ R Sbjct: 447 ENLKYGNPGATDEEIKEAAKLTHSDHFIKHLPEGYETVLTDNGEDLSQGQRQLLAITRAF 506 Query: 504 LADPRILILDEATSSIDAKTERLLQKGLNELLKGRTSFIIAHRLSTVKNCDRIMYVSNKG 563 LA+P+ILILDEATS++D KTE+ +Q + +L++G+TS IIAHRL+T+KN D I+ + + Sbjct: 507 LANPKILILDEATSNVDTKTEKSIQAAMWKLMEGKTSIIIAHRLNTIKNADLIIVLRDGE 566 Query: 564 IAESGSHDELIARRGLYHKLYTAQ 587 I E G HDELI +RG Y++L+T+Q Sbjct: 567 IVEMGKHDELIQKRGFYYELFTSQ 590 >BS_yfiC [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 285 Score = 366 bits (939), Expect = e-101, Method: Compositional matrix adjust. Identities = 0/491 (0%), Positives = 0/491 (0%) Query: 97 MTRVGQDIIFDIRTDLFAHLQQLPFKYYDDRPQGKILIRVVNYVNSVSDVLSNGIINFIL 156 M + Q + + V + + + Sbjct: 111 MIDAVELESEAAAQAQENINQSPWAERINVHTADIQQWITQQTVRFDLIISNPPYYQQGV 170 Query: 157 EIVNLIFIAAFMFAVDVRLSFVILAGLPVFLGIMLLIKTRQRRAWQAVSNKSSNLNAYMQ 216 E A S + A + + ++ S Sbjct: 171 ECSTPQREQARYTTTLDHPSLLTCAAECITEEGFFCVVLPEQIGNGFTELALSMGWHLRL 230 Query: 217 ESITGIGVTQIFSREQQNAGIFTRLAGNFRKEWMRAVSYNMLIPFSVDNLSTIVTALIFL 276 Sbjct: 231 290 Query: 277 VGLLTLDPVDATLGVILAMSSYAARFWQPILNLSNLYNSFINAVAYLERIFETLDEPVTV 336 Sbjct: 291 350 Query: 337 SDIPDARELPSVQGRVTFDHVTFAYDPGLNILENISFDVQPGESIALVGPTGAGKTTVVN 396 Sbjct: 351 410 Query: 397 LISRFYDLTGGRILIDGQDISQITLKSLRSQMGIMLQDSFIFSGTILDNIRYGKLDATEE 456 Sbjct: 411 470 Query: 457 EVIAAAKAVCADDFIREFDQGYLTEVNERGSKLSQGQRQLISFARTLLADPRILILDEAT 516 Sbjct: 471 530 Query: 517 SSIDAKTERLLQKGLNELLKGRTSFIIAHRLSTVKNCDRIMYVSNKGIAESGSHDELIAR 576 Sbjct: 531 590 Query: 577 RGLYHKLYTAQ 587 Sbjct: 591 601 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.139 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,751,666 Number of extensions: 1492327 Number of successful extensions: 20550 Number of sequences better than 1.0e-05: 1893 Number of HSP's gapped: 18602 Number of HSP's successfully gapped: 2018 Length of query: 591 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 479 Effective length of database: 25,461,023 Effective search space: 12195830017 Effective search space used: 12195830017 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 119 (50.4 bits)