BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0031.p (601 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0156 [V] COG1132 ABC-type multidrug transport system, ATPase ... 483 e-136 BS_yknU [V] COG1132 ABC-type multidrug transport system, ATPase ... 366 e-101 BH1125 [V] COG1132 ABC-type multidrug transport system, ATPase a... 365 e-101 SA1683 [V] COG1132 ABC-type multidrug transport system, ATPase a... 345 1e-94 BS_ygaD [V] COG1132 ABC-type multidrug transport system, ATPase ... 328 1e-89 >lin0156 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 580 Score = 483 bits (1242), Expect = e-136, Method: Compositional matrix adjust. Identities = 248/592 (41%), Positives = 375/592 (63%), Gaps = 15/592 (2%) Query: 11 MFELKWLWQNLEGNRARYIMALCLSVIGSSLTIVNPYLSQRIVDTFIAGDNAVQNLTDQR 70 M +KW+WQ + R + L I S ++I+ P L +++D + + + Sbjct: 1 MESMKWIWQYVRKYRLLMVGVFILIFIASGISIIYPLLGGKVIDDVVYQNKPNLLIPLLL 60 Query: 71 GLLIALCLGMIGFSLLRTGLAYFTTMQYERSSQNMLYRIRIYLYNKIQGQDREYYDHNRT 130 ++++ +++RT Y + ER QN L++IR LY K+Q D +++++ R Sbjct: 61 IMIVS--------TIIRTICRYSYQIMCERIGQNSLFQIREDLYKKLQSLDFDFFNNTRV 112 Query: 131 GDLMTKMTGDLDMVRHSMAWIFKTIIESLTIFAAAVIYFFSIDTGLTLWMLTLSPLIFIV 190 GD+M +MTGD D +RH ++W+ I+E++ +F+ A+I +ID LTL ++ ++PLI I+ Sbjct: 113 GDIMARMTGDTDAIRHFVSWVSYNILENVFLFSFAIIIMATIDWKLTLALVIITPLIAIL 172 Query: 191 AYIFAKHVRPMYVDLRERLSQLNTTTQENISGNRVVKAFAREAYEIEKFTEKNVNYSTAN 250 + +P++ ++RE S+LN+ +ENISGNRVVKAFARE +E++KF E N ++ N Sbjct: 173 TMKMSSKAQPVFYEIRESFSRLNSMVEENISGNRVVKAFAREDFEMKKFHEHNEDFKKRN 232 Query: 251 KKAALVWLDYFPYLETFAQAFNVILMLAGGLYLMDGRITFGEFAAFSSLVWAVSNPMRNI 310 +A V Y P L++ A VI ++ GG ++ G++T G+ AF+ +W ++ PMR Sbjct: 233 LDSADVSRAYLPVLDSLAGVLVVITLIFGGYLVIKGQMTLGDLVAFNGFLWMLNGPMRMS 292 Query: 311 GIIINDIQRFFASLTKIVEIYYARPAIVNEHQATTKRRYEGRITFEHVTFKYD---SATV 367 G +IND+QRF AS KI ++ A A + H +G + F +V+F ++ + V Sbjct: 293 GWLINDVQRFIASSFKIQDMM-ATNAKIPIHAEKPAPSLQGHVEFNNVSFHFEDDPNTDV 351 Query: 368 LDDVSFTVEPGETIAIMGSTGAGKTTLINLIPRFYDVSGGRVLVDGIDVRELELDELRGN 427 L ++S PG+T+AI+G TG+GK+TL+NLI RFYD + G +L+DG+D R+ + ELR + Sbjct: 352 LKNISLKASPGQTVAILGETGSGKSTLVNLICRFYDPTSGEILIDGVDARKWHVRELRNH 411 Query: 428 IGMATQDVLLFSDTIDGNIAYGDPELPEEEVVAYAGLAAAHDFIVKMPEGYDTVVGERGV 487 I QD+ LFSDTI+GNIA+G PE E+V A +A A FI MPE YDT+VGERGV Sbjct: 412 IATVMQDIFLFSDTIEGNIAFGAPEATMEDVRKMARIADADHFIETMPESYDTIVGERGV 471 Query: 488 GLSGGQKQRIALARALAVHRSILILDDTTSAVDLETEEHIQQSLRGLDYPCTKLIIAQRV 547 GLSGGQKQRI+LARAL + SILILDDTTSAVD+ETE IQ L+ + T IIA R+ Sbjct: 472 GLSGGQKQRISLARALLKNPSILILDDTTSAVDMETEVKIQGELKKITENTTTFIIAHRI 531 Query: 548 STTAEADRILILDNGRLIEEGTHAELLAKRGYYYDVFMLQNEGIGRQVMAHG 599 S+ EAD ILIL++G +IE GTHA LLA++GYY+D++ N+ +G + +G Sbjct: 532 SSVKEADEILILNHGEIIERGTHASLLAEKGYYFDIY---NKQLGTEANVNG 580 >BS_yknU [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 585 Score = 366 bits (940), Expect = e-101, Method: Compositional matrix adjust. Identities = 203/567 (35%), Positives = 325/567 (57%), Gaps = 14/567 (2%) Query: 25 RARYIMALCLSVIGSSLTIVNPYLSQRIVDTFIAGDNAVQNLTDQRGLLIALCLGMIGFS 84 R ++ +L ++ +++T+V P + Q +D + G Q L + LG I Sbjct: 15 RKVFMWSLLAMLLMTAITVVYPIILQITIDEIVLGR--------QYQLAAWVSLGFIAVM 66 Query: 85 LLRTGLAYFTTMQYERSSQNMLYRIRIYLYNKIQGQDREYYDHNRTGDLMTKMTGDLDMV 144 +L+ +F + +YR+R LY K+Q YYD+ +TGDLM+++T D++ + Sbjct: 67 VLKGMATFFHQYLGDMFGIKSVYRLRNGLYEKLQRLSFSYYDNAKTGDLMSRLTADVEGL 126 Query: 145 RHSMAWIFKTIIES--LTIFAAAVIYFFSIDTGLTLWMLTLSPLIFIVAYIFAKHVRPMY 202 R +++ +I L + +V++++S+ LTL + + P + + Y F K V P + Sbjct: 127 RFFLSYGLAELIRFGLLVAISLSVMFYYSVP--LTLVTIAVLPFLAVAVYRFDKRVHPAF 184 Query: 203 VDLRERLSQLNTTTQENISGNRVVKAFAREAYEIEKFTEKNVNYSTANKKAALVWLDYFP 262 +R+ ++LNT QENISG VK+ +RE ++I F + N Y + + +W YFP Sbjct: 185 RGIRKSFAKLNTKVQENISGINTVKSLSREDFQISTFNKANAEYRAQYLQTSSIWSAYFP 244 Query: 263 YLETFAQAFNVILMLAGGLYLMDGRITFGEFAAFSSLVWAVSNPMRNIGIIINDIQRFFA 322 +E V L+ GG +M ++ GE AF SLV + P+ N+G +IN + A Sbjct: 245 LMEFIGNTCIVALLSYGGYLVMQNQLNPGELVAFFSLVNYMMWPIMNLGFVINMFSQAKA 304 Query: 323 SLTKIVEIYYARPAIVNEHQATTKRRYEGRITFEHVTFKY--DSATVLDDVSFTVEPGET 380 S ++++I I + A K++ G + F++V+ Y + L +VSF G+ Sbjct: 305 SGERLLDILEKEEDITDHPHALHKQKLTGDVHFKNVSLAYGKEQTNALCNVSFEANSGKV 364 Query: 381 IAIMGSTGAGKTTLINLIPRFYDVSGGRVLVDGIDVRELELDELRGNIGMATQDVLLFSD 440 I ++G TG+GK+++ L+ RFY GG + +D + + L LR NIG+ Q+ LFS Sbjct: 365 IGLLGPTGSGKSSVTQLLTRFYSPVGGMITIDHKPITDYSLKTLRSNIGVVLQESFLFSS 424 Query: 441 TIDGNIAYGDPELPEEEVVAYAGLAAAHDFIVKMPEGYDTVVGERGVGLSGGQKQRIALA 500 TI NI+YG P+ E+V+ A A AH+FI+++P+GYDT++GERG+GLSGGQKQRIA+A Sbjct: 425 TIRSNISYGRPDASMEDVIEAAKRAQAHNFIMELPDGYDTMLGERGMGLSGGQKQRIAIA 484 Query: 501 RALAVHRSILILDDTTSAVDLETEEHIQQSLRGLDYPCTKLIIAQRVSTTAEADRILILD 560 RA+ ++ SILILDD TSAVD++TE IQ +L+ + T I+A R+S+ AD IL+ + Sbjct: 485 RAICLNPSILILDDATSAVDMQTEHSIQLALKEVMKNRTTFIVAHRISSLKHADEILVFN 544 Query: 561 NGRLIEEGTHAELLAKRGYYYDVFMLQ 587 GR+ E GTH ELL K GYY ++ LQ Sbjct: 545 KGRIRERGTHHELLEKGGYYKKIYDLQ 571 >BH1125 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 581 Score = 365 bits (938), Expect = e-101, Method: Compositional matrix adjust. Identities = 199/489 (40%), Positives = 304/489 (62%), Gaps = 9/489 (1%) Query: 106 LYRIRIYLYNKIQGQDREYYDHNRTGDLMTKMTGDLDMVRHSMAWIFKTIIESLTI--FA 163 +YR+R LY K+Q YYD+ +TGDLM+++TGD++ R +++ F I+ + + F+ Sbjct: 88 VYRLRNSLYEKLQYLPFRYYDNAKTGDLMSRLTGDVETFRFFLSFGFAQFIQFILLVSFS 147 Query: 164 AAVIYFFSIDTGLTLWMLTLSPLIFIVAYIFAKHVRPMYVDLRERLSQLNTTTQENISGN 223 V+ ++S+ LTL + P + IV F + V P + D+R+ L++LNT QEN+SG Sbjct: 148 MGVMLYYSVP--LTLATMCTLPFLAIVVAKFDRRVHPGFRDIRKSLAKLNTKVQENVSGM 205 Query: 224 RVVKAFAREAYEIEKFTEKNVNYSTANKKAALVWLDYFPYLETFAQAFNVILMLAGGLYL 283 VKA ++E E+ +F ++NV+Y + A VW +YFP +E V L+ GG + Sbjct: 206 NTVKALSQEDEEVSRFEDRNVDYRQKHLDIARVWGNYFPLMEFIGNLSAVFLLSFGGYLV 265 Query: 284 MDGRITFGEFAAFSSLVWAVSNPMRNIGIIINDIQRFFASLTKIVEIYYARPAIVNEHQA 343 + G + G+ AF SLVW + P+ N+G IIN + AS +++EI + + Sbjct: 266 ITGSMQTGQLVAFFSLVWYIIGPIMNLGFIINTFSQSKASGERLLEILDEENRV--DEGK 323 Query: 344 TTKRRYEGRITFEHVTFKYDSA--TVLDDVSFTVEPGETIAIMGSTGAGKTTLINLIPRF 401 + +G +TF V Y A L +VSF G+TI ++G+TG+GKT+++ L+ RF Sbjct: 324 DERTSLQGSVTFRDVCLNYRGAETPALQNVSFEAPAGKTIGLVGATGSGKTSIVQLVNRF 383 Query: 402 YDVSGGRVLVDGIDVRELELDELRGNIGMATQDVLLFSDTIDGNIAYGDPELPEEEVVAY 461 Y+ + G +L+DG + L+ LR IG+ Q+ LFS TI NIAYG P++ +E++A Sbjct: 384 YERTSGEILIDGKPIESYPLETLRSQIGVVLQESFLFSSTIRDNIAYGRPDVSMKEIIAA 443 Query: 462 AGLAAAHDFIVKMPEGYDTVVGERGVGLSGGQKQRIALARALAVHRSILILDDTTSAVDL 521 A A AHDFI ++P+GYDTV+GERG+GLSGGQKQRIA+ARA+ ++ SILILDD TSAVD+ Sbjct: 444 ARRAQAHDFIAELPDGYDTVLGERGLGLSGGQKQRIAIARAILMNPSILILDDATSAVDM 503 Query: 522 ETEEHIQQSLRGLDYPCTKLIIAQRVSTTAEADRILILDNGRLIEEGTHAELLA-KRGYY 580 +TE IQ + R + T IIA R+S+ +AD IL+LD G++ E GTH LL K+G Y Sbjct: 504 KTEHKIQAAFREVMKGRTTFIIAHRISSVKQADEILVLDGGKVCERGTHHTLLQNKKGLY 563 Query: 581 YDVFMLQNE 589 ++ +Q++ Sbjct: 564 RRIYDIQSK 572 >SA1683 [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 578 Score = 345 bits (884), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 201/579 (34%), Positives = 328/579 (56%), Gaps = 7/579 (1%) Query: 14 LKWLWQNLEGNRARYIMALCLSVIGSSLTIVNPYLSQRIVDTFIAGDNAVQNLTDQRGLL 73 +K Q ++ + R + + +I + ++ P L + +D I ++A+ L Sbjct: 2 IKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGVI-NNHALTTDEKVHHLT 60 Query: 74 IALCLGMIGFSLLRTGLAYFTTMQYERSSQNMLYRIRIYLYNKIQGQDREYYDHNRTGDL 133 IA+ + + F ++R + + + +S +LY IR LYN +Q +Y +N+ G + Sbjct: 61 IAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYNHLQALSARFYANNQVGQV 120 Query: 134 MTKMTGDLDMVRH-SMAWIFKTIIESLTIFAAAVIYFFSIDTGLTLWMLTLSPLIFIVAY 192 ++++ D++ + + + ++ +TI A I FF +D LTL L + P + Y Sbjct: 121 ISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFF-LDVKLTLAALFIFPFYILTVY 179 Query: 193 IFAKHVRPMYVDLRERLSQLNTTTQENISGNRVVKAFAREAYEIEKFTEKNVNYSTANKK 252 +F +R + + + L+++ E + G VVK+FA E E + F +KN N+ T K Sbjct: 180 VFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAIEDNEAKNFDKKNTNFLTRALK 239 Query: 253 AALVWLDY-FPYLETFAQAFNVILMLAGGLYLMDGRITFGEFAAFSSLVWAVSNPMRNIG 311 W Y F + T +I++ G + G IT G AAF + + P+R + Sbjct: 240 HTR-WNAYSFAAINTVTDIGPIIVIGVGAYLAISGSITVGTLAAFVGYLELLFGPLRRLV 298 Query: 312 IIINDIQRFFASLTKIVEIYYARPAIVNEHQATTKRRYEGRITFEHVTFKYD--SATVLD 369 + + FAS+ ++ ++ I N A +GRI +HV+F+Y+ A +L Sbjct: 299 ASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIEIKQGRIDIDHVSFQYNDNEAPILK 358 Query: 370 DVSFTVEPGETIAIMGSTGAGKTTLINLIPRFYDVSGGRVLVDGIDVRELELDELRGNIG 429 D++ ++E GET+A +G +G GK+TLINLIPRFYDV+ G++L+DG ++++ LR IG Sbjct: 359 DINLSIEKGETVAFVGMSGGGKSTLINLIPRFYDVTSGQILIDGHNIKDFLTGSLRNQIG 418 Query: 430 MATQDVLLFSDTIDGNIAYGDPELPEEEVVAYAGLAAAHDFIVKMPEGYDTVVGERGVGL 489 + QD +LFSDT+ NI G P +EEVV A +A AHDFI+ +P+GYDT VGERGV L Sbjct: 419 LVQQDNILFSDTVKENILLGRPTATDEEVVEAAKMANAHDFIMNLPQGYDTEVGERGVKL 478 Query: 490 SGGQKQRIALARALAVHRSILILDDTTSAVDLETEEHIQQSLRGLDYPCTKLIIAQRVST 549 SGGQKQR+++AR + ILILD+ TSA+DLE+E IQ++L L T LI+A R+ST Sbjct: 479 SGGQKQRLSIARIFLNNPPILILDEATSALDLESESIIQEALDVLSKDRTTLIVAHRLST 538 Query: 550 TAEADRILILDNGRLIEEGTHAELLAKRGYYYDVFMLQN 588 AD+I++++NG ++E GTH EL+AK+G Y ++ +QN Sbjct: 539 ITHADKIVVIENGHIVETGTHRELIAKQGAYEHLYSIQN 577 >BS_ygaD [V] COG1132 ABC-type multidrug transport system, ATPase and permease components Length = 165 Score = 328 bits (842), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 0/578 (0%), Positives = 0/578 (0%), Gaps = 6/578 (1%) Query: 14 LKWLWQNLEGNRARYIMALCLSVIGSSLTIVNPYLSQRIVDTFIAGDNAVQNLTDQRGLL 73 + + V I + + Q + + L Sbjct: 13 VGQALKARGATVTTAESCTGGWVAKVITDIAGSSAWFERGFVTYSNEAKAQMIGVREETL 72 Query: 74 IALCLGMIGFSLLRTGLAYFTTMQYERSSQNMLYRIRIYLYNKIQGQDREYYDHNRTGDL 133 ++ + ++ ++ + ++ Sbjct: 73 AQHGAVS--EPVVVEMAIGALKAARADYAVSISGIAGPDGGSEEKPVGTVWFAFATARGE 130 Query: 134 MTKMTGDLDMVRH-SMAWIFKTIIESLTIFAAAVIYFFSIDTGLTLWMLTLSPLIFIVAY 192 R +++L Sbjct: 131 GITRRECFSGDRDAVRRQATAYALQTLWQQFLQNT- 189 Query: 193 IFAKHVRPMYVDLRERLSQLNTTTQENISGNRVVKAFAREAYEIEKFTEKNVNYSTANKK 252 Sbjct: 190 249 Query: 253 AALVWLDYFPYLETFAQAFNVILMLAGGLYLMDGRITFGEFAAFSSLVWAVSNPMRNIGI 312 Sbjct: 250 309 Query: 313 IINDIQRFFASLTKIVEIYYARPAIVNEHQATTKRRYEGRITFEHVTFKY--DSATVLDD 370 Sbjct: 310 369 Query: 371 VSFTVEPGETIAIMGSTGAGKTTLINLIPRFYDVSGGRVLVDGIDVRELELDELRGNIGM 430 Sbjct: 370 429 Query: 431 ATQDVLLFSDTIDGNIAYGDPELPEEEVVAYAGLAAAHDFIVKMPEGYDTVVGERGVGLS 490 Sbjct: 430 489 Query: 491 GGQKQRIALARALAVHRSILILDDTTSAVDLETEEHIQQSLRGLDYPCTKLIIAQRVSTT 550 Sbjct: 490 549 Query: 551 AEADRILILDNGRLIEEGTHAELLAKRGYYYDVFMLQN 588 Sbjct: 550 587 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.323 0.138 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 44,200,881 Number of extensions: 1838718 Number of successful extensions: 20126 Number of sequences better than 1.0e-05: 1820 Number of HSP's gapped: 17831 Number of HSP's successfully gapped: 1942 Length of query: 601 Length of database: 38,378,431 Length adjustment: 112 Effective length of query: 489 Effective length of database: 25,461,023 Effective search space: 12450440247 Effective search space used: 12450440247 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 119 (50.4 bits)