BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0022.p (1115 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value MA2418 [V] COG4096 Type I site-specific restriction-modification... 847 0.0 SP0892 [V] COG4096 Type I site-specific restriction-modification... 799 0.0 NMA2106 [K] COG0583 Transcriptional regulator 413 e-114 MA2106 [V] COG4096 Type I site-specific restriction-modification... 413 e-114 alr3473 [V] COG4096 Type I site-specific restriction-modificatio... 175 3e-43 >MA2418 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Length = 1146 Score = 847 bits (2188), Expect = 0.0, Method: Compositional matrix adjust. Identities = 480/1147 (41%), Positives = 692/1147 (60%), Gaps = 52/1147 (4%) Query: 4 NFEFLLGQPEYKLFANACIEAERVLATSPAMAAVGSRKAFELAVKWVYAADNTITMPYKD 63 NF FL + E+ A +A + P A +R+A ELAV+W+Y D T+ +PY+D Sbjct: 3 NFAFL--ETEWPSLYEAAEKASNAVYPDPRTACFYARRALELAVQWMYKHDYTLLLPYQD 60 Query: 64 NLQALIHEPTFKFAMENQTWGKLPYIIKLGNLAVHTDKXXXXXXXXXXXXXXFEFIQWLD 123 NL AL+HEPTFK A + K II+LGN AVH++ F WL Sbjct: 61 NLSALVHEPTFKKAAGEAIFNKARIIIRLGNQAVHSNSTVLLHDSLTAVSELFHISYWLA 120 Query: 124 YCY--------GVNYEERHFAEDNIP---VEKVVLDEARIKEKDSLIEQKESEIEALRAQ 172 Y G+++ + +P +E++ EA ++EKD +K SE+ A ++ Sbjct: 121 RTYARKEKPEPGLSFNPDELPKTTVPKQTIEQLQKLEASLQEKD----EKLSELLADKSA 176 Query: 173 IAAMSDRLTADKEQHQEERHFTPE--DISEFRTRKKYIDVDLKLLGWTLGDDAREEVELY 230 + RL A+ + +E P+ D SE TRK ID+ LK GW L +E E+ Sbjct: 177 MDEELKRLRAEVAKAKEASTLLPDTHDYSEAETRKSLIDLLLKEAGWPLDKTQDKEFEVL 236 Query: 231 GMPNDEGKGYADYVLYGKDGLPLAIIEAKRTSKDPKAGTHQAKLYADCLERMTGRRPMMF 290 GMPN G GY DYVL+G DG PLA++EAKRT+KDP+ G QAKLYA+CLE G+RP++F Sbjct: 237 GMPNKNGVGYVDYVLWGDDGKPLALVEAKRTTKDPQVGQQQAKLYANCLENQFGQRPVIF 296 Query: 291 TSNGFETNLWDDVTSPQRKVSGVFSKSDLQKLMNRRNERKVLDEVVIDDNITDRYYQKEA 350 SNG+ET +WDD P R+V G + K++L+ L+ RR+ R+ L E I+ I +RYYQ A Sbjct: 297 YSNGYETWIWDDSLYPPRQVQGFYKKAELELLIQRRSSRRPLSEAEINSAIVERYYQTRA 356 Query: 351 IRAVCDNI-MTGHRRSLLVMATGTGKTRTASSLTDVLSRGGYVTNILFLADRKALVKQAK 409 IR + + R++L+VMATG GKTRT +L D+L R +V +LFLADR ALV QA Sbjct: 357 IRRIGEAFEQDNDRKALIVMATGAGKTRTVIALCDLLMRCNWVKRVLFLADRVALVNQAV 416 Query: 410 DDFKNYLPDMSLCNLLSNKDDKTARIVFSTYPTMLNAIDRAKSDDGKRLFTPAHFDLIIV 469 + FK +LPD + NL++ KD + R+ STYPTM+ I+ + + G+R F HFDL+I+ Sbjct: 417 NAFKRHLPDSAPVNLVTEKDTE-GRVFVSTYPTMMKQIE--EINGGQRRFGVGHFDLVII 473 Query: 470 DEAHRSIFKKFRAIFEYFDGYVVGLTATPKTDVDRNTYDFFEMESGVPTYAYPYETAVEM 529 DEAHRS+FKK+RAIF+YFD +VGLTATPK +++RNTY F++E GVPT AY E AV+ Sbjct: 474 DEAHRSVFKKYRAIFDYFDSLLVGLTATPKNEIERNTYSLFDLEPGVPTDAYQLEEAVK- 532 Query: 530 DRVLVPYHNIEVTTKVLEQGITYDTLSADDKARYEE-DFTEEDGEMPEFIPSPAINDFIF 588 D LVP + V K QGI YD LS +DK ++E D+ +EDGE+PE + + A+N ++F Sbjct: 533 DGFLVPPKAVSVPLKFQRQGINYDELSDEDKEQWEALDWGDEDGEIPERVEAEAVNKWLF 592 Query: 589 NQATVDQVLEDLMTQGIKVSGGDRLGKTIIFAQNKNHAQYIVERFNKLYPQYKGDFAKRI 648 N+ TVD+VL LM +G+KV+GGDRLGKTI+FA+N+ HA+Y+ ERFN YP +KG+FA+ I Sbjct: 593 NKDTVDKVLAHLMERGLKVAGGDRLGKTILFAKNQAHAEYVAERFNVNYPHFKGEFARVI 652 Query: 649 VSEDDYTQSLIDDFKLANKSPYIAVSVDMLDTGIDVPEIVNLVFFKRIRSKTKFWQMIGR 708 + +Y QSLID+F + K P+IA+SVDMLDTGIDVPE+VNLVFFK +RSKTKFWQM+GR Sbjct: 653 TFKTEYAQSLIDNFSIKEKDPHIALSVDMLDTGIDVPEVVNLVFFKLVRSKTKFWQMVGR 712 Query: 709 GTRLCKDLFGEGEDKTHFVIFDYLGNFEFFRQHKEGLQGNEAYSLSEVIFAKRIRLIQHL 768 GTRLC DLF GEDK F +FDY N EFF Q+ E +G SL +F R+ L+ L Sbjct: 713 GTRLCPDLFEPGEDKRFFYLFDYCQNLEFFSQNPETTEGALGDSLGTRLFKSRLELLSEL 772 Query: 769 QQAVFID--------------EPY--QSIRTDLIEIVIGQIQALNTELVSVKMQLQYIEK 812 + + D EP +R + E + +I ++N + V+ + + +E+ Sbjct: 773 DKKLEADSDCEVGTETREIYGEPITEAEVRHSIAETLHSEIASMNLDNFVVRPKRRLVER 832 Query: 813 YKHQAAFVCLLEQDQSNLIKYVAPIVY-MDDADEHAKRFDNLLYGLMLAQAEEAPQYKKS 871 Y A++ L +D S L VA + M+ E AKRFD L+ L LA P +++ Sbjct: 833 YSRSEAWLKLSGEDLSELSHEVAGLPSEMEPEAEEAKRFDLLVLNLQLALLRAEPAFERL 892 Query: 872 KKQLIDVATTLLQRATIPQVRDKLTLIQTIGTEEFWDSANLLDFEKVRQELRGLIKFIVD 931 + Q+ D+A L +++ IP VRD++ LI + T+E+W++ E +R+ LR ++K I + Sbjct: 893 RNQVRDIAGLLEEKSAIPMVRDQMALILDVQTDEWWENVTTPMLETLRRRLRDIVKLI-E 951 Query: 932 EGGKNPIYTNLADEVLEVH--EGKAMYEAYTFEDYKLKVNRYIEKNRDNLVIHKLRNNIP 989 + + PIYT+ DE+ + E A FE ++ K ++ +++D VIHKLR N P Sbjct: 952 KHRRKPIYTDFEDEMGSENNVELPGFAAAGDFEKFRAKTRAFLLEHQDQAVIHKLRMNKP 1011 Query: 990 LTALDYEALEKIFT-GELGTAED--YEREFKDTPFGLLVRKIAKLEYAAATAAFSEFIND 1046 LTA D + LE+I + LG E+ + +E + GL VR + L+ AA +F+ F+ Sbjct: 1012 LTAADLDELERILSESGLGGPEEIAHAKEVSNG-LGLFVRSLIGLDREAAKQSFARFLAG 1070 Query: 1047 QSLSQGQIVFVKKVIDYIVQNGYIDNVTELTKPPFD--KPQSFVKLFDGTKQRRLVETVA 1104 ++L QI F+ ++ID++ ++G +D L + PF PQ LF + L+ + Sbjct: 1071 KTLVANQIEFINRIIDHLTEHGAMDAAL-LYESPFTDLTPQGPDGLFTSAQVDELIAALE 1129 Query: 1105 QIKENAV 1111 QI A+ Sbjct: 1130 QITATAL 1136 >SP0892 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Length = 1091 Score = 799 bits (2064), Expect = 0.0, Method: Compositional matrix adjust. Identities = 443/1094 (40%), Positives = 676/1094 (61%), Gaps = 25/1094 (2%) Query: 27 VLATSPAMAAVGSRKAFELAVKWVYAADNTITMPYKDNLQALIHEPTFKFAMENQTWGKL 86 ++ATS A +R+A E AV W+Y+ D+ + PY+ L +L+ + F+ ++++ ++ Sbjct: 1 MIATSTVATAFMARRALEQAVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQI 60 Query: 87 PYIIKLGNLAVHTDKXXXXXXXXXXXXXXFEFIQWLDYCYGVNYEERHFAEDNIPVEKVV 146 +I+ GN A H + ++F+ ++DYCY + ER+F E +P+ + Sbjct: 61 VLLIRWGNHAAHGGEIKEREAILALHHL-YQFVNFIDYCYSNEFVERYFDEKCLPLSANI 119 Query: 147 ----LDEARIKEKDSLIEQKESEIEALRAQIAAMSDRLTADKEQ--HQEERHFTPEDISE 200 ++ IK +DSL E + E + AQ + + T +E +++ F + +SE Sbjct: 120 KYRETPQSMIKLQDSLPELPDFH-EQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSE 178 Query: 201 FRTRKKYIDVDLKLLGWTLGDDAREEVELYGMPNDEGKGYADYVLYGKDGLPLAIIEAKR 260 TRK +ID+DL+L GW ++ R E+ + G+ + G GY DYVLYGK+G LAI+EAK+ Sbjct: 179 AETRKLFIDIDLRLAGWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKK 238 Query: 261 TSKDPKAGTHQAKLYADCLERMTGRRPMMFTSNGFETNLWDDVTSPQRKVSGVFSKSDLQ 320 S +P+ G Q K YA+ LE+ G +P+ F +NG + + D +R+++G +S+ +LQ Sbjct: 239 ASVNPEVGEVQVKEYAEALEKHIGYQPICFITNGLKHYILDGPN--RRQIAGFYSQEELQ 296 Query: 321 KLMNRRNERKVLDEVV--IDDNITDRYYQKEAIRAVCDNIMTGHRRSLLVMATGTGKTRT 378 +M+RR+ +K L+++ I D+I+ R+YQK AI +VC+ R++LLVMATG GKTRT Sbjct: 297 LVMDRRHLQKPLEDISSKIRDDISGRHYQKHAIASVCEAFSDHRRQALLVMATGAGKTRT 356 Query: 379 ASSLTDVLSRGGYVTNILFLADRKALVKQAKDDFKNYLPDMSLCNLLSNKDD-KTARIVF 437 A SL D+LSR +V N+LFLADR +LVKQA D F+ LPD+S+CN L +K+ +++R+VF Sbjct: 357 AVSLVDILSRHNWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVF 416 Query: 438 STYPTMLNAIDRAKSDDGKRLFTPAHFDLIIVDEAHRSIFKKFRAIFEYFDGYVVGLTAT 497 STYPTM+ AI + + +R FT HFDLII+DE+HRSI++K+++IF+YFD +VGLTAT Sbjct: 417 STYPTMIGAIS-GQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTAT 475 Query: 498 PKTDVDRNTYDFFEMESGVPTYAYPYETAVEMDRVLVPYHNIEVTTKVLEQGITYDTLSA 557 P+ D+D+NTY FF +E+GVPTYAY E AV+ D LV YH+IE K+ G+ YD LS Sbjct: 476 PRQDLDKNTYGFFNLENGVPTYAYDLEEAVK-DGYLVAYHSIETKLKLPTDGLHYDDLSE 534 Query: 558 DDKARYEEDFTEEDGEMPEFIPSPAINDFIFNQATVDQVLEDLMTQGIKVSGGDRLGKTI 617 ++K ++ F ED + I N FIFN++TV+ VL +LMT+GI+ + GD +GKTI Sbjct: 535 EEKEHFDSKF--EDNSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTI 592 Query: 618 IFAQNKNHAQYIVERFNKLYPQYKGDFAKRIVSEDDYTQSLIDDFKLANKSPYIAVSVDM 677 IFA+N +HA+YI FN YP+ D+A+ I + Q+LIDDFK+ K P IA+SVDM Sbjct: 593 IFAKNHDHAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDM 652 Query: 678 LDTGIDVPEIVNLVFFKRIRSKTKFWQMIGRGTRLCKDLFGEGEDKTHFVIFDYLGNFEF 737 LDTGIDVPE+VNLVFFK++RSKTKFWQMIGRGTRLCKDLFG +DK +F++FDY NF++ Sbjct: 653 LDTGIDVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDY 712 Query: 738 FRQHKEGLQGNEAYSLSEVIFAKRIRLIQHLQQAVFIDEPY-QSIRTDLIEIVIGQIQAL 796 FR +G SL++ +F ++ LI+ LQ + ++ + ++ R L+ + G+I++L Sbjct: 713 FRADPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESL 772 Query: 797 NTELVSVKMQLQYIEKYKHQAAFVCLLEQDQSNLIKYVAPIVYMDDA-DEHAKRFDNLLY 855 N V+M L + Y+ ++ L + K ++P+++ +D DE A+RFD L Sbjct: 773 NELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWLL 832 Query: 856 GLMLAQAEEAPQYKKSKKQLIDVATTLLQRATIPQVRDKLTLIQTIGTEEFWDSANLLDF 915 + L Q A Q++ A L IPQV ++ +I+ + EFW NL D Sbjct: 833 HIQLGQL-TAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLSDL 891 Query: 916 EKVRQELRGLIKFIVDEGGKNPIYTNLADEVLE-VHEGKAMYEAYTFEDYKLKVNRYIEK 974 EK+R +R L++F+ D+ + P Y N D +L VHE A + Y KV Y++ Sbjct: 892 EKIRLAIRDLLQFL-DKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHYLKT 950 Query: 975 NRDNLVIHKLRNNIPLTALDYEALEKIFTGELGTAEDYEREFKDTPFGLLVRKIAKLEYA 1034 + D I KL +N LT+ D ALEK+ +LG+ DY+ +++ LVR+I L+ Sbjct: 951 HLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREIIGLDRE 1010 Query: 1035 AATAAFSEFINDQSLSQGQIVFVKKVIDYIVQNGYIDNVTELTKPPFDKPQSFVKLFDGT 1094 +A FS+F++D++L+ QI FVK ++DYIV+NG+++ LT+ PF S LF Sbjct: 1011 SANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKV-LTQEPFKSYGSVQLLF--Q 1067 Query: 1095 KQRRLVETVAQIKE 1108 Q ++ + QI E Sbjct: 1068 HQLPVLRNIVQIIE 1081 >NMA2106 [K] COG0583 Transcriptional regulator Length = 955 Score = 413 bits (1061), Expect = e-114, Method: Compositional matrix adjust. Identities = 292/840 (34%), Positives = 445/840 (52%), Gaps = 55/840 (6%) Query: 197 DISEFRTRKKYIDVDLKLLGWTLGDDAREEVEL----------------YGMPNDEGKGY 240 D++EF+TRK ID+ LK GW + D ++ +E+ ND Y Sbjct: 5 DLNEFQTRKLKIDILLKEQGWDVNDRSKVVLEVDTKQSDFKKQDYKQVNETRRNDAESKY 64 Query: 241 ADYVLYGKDGLPLAIIEAKRTSKDPKAGTHQAKLYADCLERMTGRRPMMFTSNGFETNLW 300 ADY+L G PLAIIEAKRT+KDP G QA+ YAD ++ TG+ +F SNG++ LW Sbjct: 65 ADYLLLDSTGKPLAIIEAKRTTKDPILGQKQAEEYADDIKAQTGKEVFIFLSNGYQIWLW 124 Query: 301 DDVTSPQRKVSGVFSKSDLQKLMNRRNERKVLDEVVIDDNITDRYYQKEAIRAVCDNIMT 360 D R++ G +S DL++L+ +R ++ E+ ID +I DR E V ++I Sbjct: 125 DRERYGPRQLKGFYSLKDLERLLYQRKNSELEAEIDIDGSIVDRAKSIEVATRVVEHIHK 184 Query: 361 GHRRSLLVMATGTGKTRTASSLTDVLSRGGYVTNILFLADRKALVKQA-KDDFKNYLPDM 419 GHR++L+VMATGTGKTR A ++ D L R G V +LFL DRKAL KQA + + + P+ Sbjct: 185 GHRKALIVMATGTGKTRVAMAIIDQLIREGRVQRVLFLTDRKALRKQAYEKGYLRFFPEE 244 Query: 420 SLCNLLSNKDDKTARIVFSTYPTMLNAIDRAKSDDGKRLFTPAHFDLIIVDEAHRSIFKK 479 + +LS + R+ ST T ++ ++ R+ +P FDLI DEAHRSI+ K Sbjct: 245 TKEIILSGNYNSNCRLYVSTIQTFQEIYNQKDRNEMYRI-SPGAFDLIFSDEAHRSIYSK 303 Query: 480 FRAIFEYFDGYVVGLTATPKTDVDRNTYDFFEMESGVPTYAYPYETAVEMDRVLVPYH-N 538 ++ IF Y D +GLTATP VDR+T+ FFE +PT Y YE AV D VL + N Sbjct: 304 WKGIFTYLDAIQIGLTATPADMVDRDTFRFFECNDDIPTALYSYEDAVR-DAVLCDFRKN 362 Query: 539 IEVTTKVLE-QGITYDTLSADDKARYEEDFTEEDGEMPEFI--PSPAINDFIFNQATVDQ 595 I + +GI + L+ ++ E+ ++ G P+ I + I + T + Sbjct: 363 ISGARTYFQIEGIKPENLTEGER----EELIKK-GIDPDEINFEGTELEKKIAVKGTSEA 417 Query: 596 VLEDLMTQGIKVSGGDRLGKTIIFAQNKNHAQYIVERFNKLYPQYKGDFAKRIVSEDDYT 655 ++ + M + G KTI FA +K HA+ + E F KLYP+YKG A+ IVSED Sbjct: 418 IVREFMENCLTDQAGTLPAKTIFFAISKLHAKRLWEAFEKLYPEYKGKLARIIVSEDSRA 477 Query: 656 QSLIDDFKLANKSPYIAVSVDMLDTGIDVPEIVNLVFFKRIRSKTKFWQMIGRGTR---L 712 Q LI DF+ P IA+SVDM+DTGIDVPE+ NLVF K + SK KFWQM+GRGTR Sbjct: 478 QQLIKDFE-EKPFPRIAISVDMMDTGIDVPEVCNLVFAKPVFSKIKFWQMLGRGTRADGA 536 Query: 713 C--KDLFGEGEDKTHFVIFDYLGNFEFFRQHKEGLQGNEAYSLSEVIFAKRIRLIQHLQQ 770 C ++ +G+ K +F +FD+ NFE++ + EG+Q A +++ IF R++ + L Q Sbjct: 537 CEHREWLPDGK-KEYFKVFDFWNNFEYWNMNPEGVQNESAEAITNRIFLTRLKQLGELMQ 595 Query: 771 AVFIDEPYQSIRTDLIEIVIGQIQALNTELVSVKMQLQYIEKYKHQAAF-------VCLL 823 D + + +I I++L + V+V+ LQ +EK + V L Sbjct: 596 HR--DPASEKAAEQVKAKIISDIESLPRDSVNVREHLQDVEKALSPKLWDNIAVDPVEFL 653 Query: 824 EQDQSNLIKYVAPIVYMDDADEHAKRFDNLLYGLMLAQAEEAPQYKKSKKQLIDVATTLL 883 ++ L+K+ P V + +A R + L Y L+ E + K S +++D L Sbjct: 654 QKKIMPLMKF-KPDVNLKEA-TFTLRCEKLAYALLENDKAEIDRLKTSIAEMVD----RL 707 Query: 884 QRATIPQVRDKLTLIQTIGTEEFWDSANLLDFEKVRQELRGLIKFIVDEGGKNPIYTNLA 943 R T+ VR K L+ + + FW++ + D + + +L L+ ++ E + I +++ Sbjct: 708 PR-TLDSVRAKEALMDNVLSRSFWETVSFEDVQLLLSDLAPLMPYMAKE-PRETIVIDMS 765 Query: 944 DEVLEVHEGK--AMYEAYTFEDYKLKVNRYIEK-NRDNLVIHKLRNNIPLTALDYEALEK 1000 D + E E + + E Y+ +V I + + K++NN PLT D E LE+ Sbjct: 766 DIIAERKEWQISGGNDPSYVEAYRREVEACIRALAETHPAVRKIKNNEPLTDYDLEQLEE 825 >MA2106 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Length = 955 Score = 413 bits (1061), Expect = e-114, Method: Compositional matrix adjust. Identities = 292/840 (34%), Positives = 445/840 (52%), Gaps = 55/840 (6%) Query: 197 DISEFRTRKKYIDVDLKLLGWTLGDDAREEVEL----------------YGMPNDEGKGY 240 D++EF+TRK ID+ LK GW + D ++ +E+ ND Y Sbjct: 5 DLNEFQTRKLKIDILLKEQGWDVNDRSKVVLEVDTKQSDFKKQDYKQVNETRRNDAESKY 64 Query: 241 ADYVLYGKDGLPLAIIEAKRTSKDPKAGTHQAKLYADCLERMTGRRPMMFTSNGFETNLW 300 ADY+L G PLAIIEAKRT+KDP G QA+ YAD ++ TG+ +F SNG++ LW Sbjct: 65 ADYLLLDSTGKPLAIIEAKRTTKDPILGQKQAEEYADDIKAQTGKEVFIFLSNGYQIWLW 124 Query: 301 DDVTSPQRKVSGVFSKSDLQKLMNRRNERKVLDEVVIDDNITDRYYQKEAIRAVCDNIMT 360 D R++ G +S DL++L+ +R ++ E+ ID +I DR E V ++I Sbjct: 125 DRERYGPRQLKGFYSLKDLERLLYQRKNSELEAEIDIDGSIVDRAKSIEVATRVVEHIHK 184 Query: 361 GHRRSLLVMATGTGKTRTASSLTDVLSRGGYVTNILFLADRKALVKQA-KDDFKNYLPDM 419 GHR++L+VMATGTGKTR A ++ D L R G V +LFL DRKAL KQA + + + P+ Sbjct: 185 GHRKALIVMATGTGKTRVAMAIIDQLIREGRVQRVLFLTDRKALRKQAYEKGYLRFFPEE 244 Query: 420 SLCNLLSNKDDKTARIVFSTYPTMLNAIDRAKSDDGKRLFTPAHFDLIIVDEAHRSIFKK 479 + +LS + R+ ST T ++ ++ R+ +P FDLI DEAHRSI+ K Sbjct: 245 TKEIILSGNYNSNCRLYVSTIQTFQEIYNQKDRNEMYRI-SPGAFDLIFSDEAHRSIYSK 303 Query: 480 FRAIFEYFDGYVVGLTATPKTDVDRNTYDFFEMESGVPTYAYPYETAVEMDRVLVPYH-N 538 ++ IF Y D +GLTATP VDR+T+ FFE +PT Y YE AV D VL + N Sbjct: 304 WKGIFTYLDAIQIGLTATPADMVDRDTFRFFECNDDIPTALYSYEDAVR-DAVLCDFRKN 362 Query: 539 IEVTTKVLE-QGITYDTLSADDKARYEEDFTEEDGEMPEFI--PSPAINDFIFNQATVDQ 595 I + +GI + L+ ++ E+ ++ G P+ I + I + T + Sbjct: 363 ISGARTYFQIEGIKPENLTEGER----EELIKK-GIDPDEINFEGTELEKKIAVKGTSEA 417 Query: 596 VLEDLMTQGIKVSGGDRLGKTIIFAQNKNHAQYIVERFNKLYPQYKGDFAKRIVSEDDYT 655 ++ + M + G KTI FA +K HA+ + E F KLYP+YKG A+ IVSED Sbjct: 418 IVREFMENCLTDQAGTLPAKTIFFAISKLHAKRLWEAFEKLYPEYKGKLARIIVSEDSRA 477 Query: 656 QSLIDDFKLANKSPYIAVSVDMLDTGIDVPEIVNLVFFKRIRSKTKFWQMIGRGTR---L 712 Q LI DF+ P IA+SVDM+DTGIDVPE+ NLVF K + SK KFWQM+GRGTR Sbjct: 478 QQLIKDFE-EKPFPRIAISVDMMDTGIDVPEVCNLVFAKPVFSKIKFWQMLGRGTRADGA 536 Query: 713 C--KDLFGEGEDKTHFVIFDYLGNFEFFRQHKEGLQGNEAYSLSEVIFAKRIRLIQHLQQ 770 C ++ +G+ K +F +FD+ NFE++ + EG+Q A +++ IF R++ + L Q Sbjct: 537 CEHREWLPDGK-KEYFKVFDFWNNFEYWNMNPEGVQNESAEAITNRIFLTRLKQLGELMQ 595 Query: 771 AVFIDEPYQSIRTDLIEIVIGQIQALNTELVSVKMQLQYIEKYKHQAAF-------VCLL 823 D + + +I I++L + V+V+ LQ +EK + V L Sbjct: 596 HR--DPASEKAAEQVKAKIISDIESLPRDSVNVREHLQDVEKALSPKLWDNIAVDPVEFL 653 Query: 824 EQDQSNLIKYVAPIVYMDDADEHAKRFDNLLYGLMLAQAEEAPQYKKSKKQLIDVATTLL 883 ++ L+K+ P V + +A R + L Y L+ E + K S +++D L Sbjct: 654 QKKIMPLMKF-KPDVNLKEA-TFTLRCEKLAYALLENDKAEIDRLKTSIAEMVD----RL 707 Query: 884 QRATIPQVRDKLTLIQTIGTEEFWDSANLLDFEKVRQELRGLIKFIVDEGGKNPIYTNLA 943 R T+ VR K L+ + + FW++ + D + + +L L+ ++ E + I +++ Sbjct: 708 PR-TLDSVRAKEALMDNVLSRSFWETVSFEDVQLLLSDLAPLMPYMAKE-PRETIVIDMS 765 Query: 944 DEVLEVHEGK--AMYEAYTFEDYKLKVNRYIEK-NRDNLVIHKLRNNIPLTALDYEALEK 1000 D + E E + + E Y+ +V I + + K++NN PLT D E LE+ Sbjct: 766 DIIAERKEWQISGGNDPSYVEAYRREVEACIRALAETHPAVRKIKNNEPLTDYDLEQLEE 825 >alr3473 [V] COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Length = 359 Score = 175 bits (444), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 0/586 (0%), Positives = 0/586 (0%), Gaps = 93/586 (15%) Query: 198 ISEFRTRKKYIDVDLKLLGWTLGDDAREEVELY-------GMPNDEG-KGYADYVLYGKD 249 R + + A + G + + Sbjct: 10 RRALRHNLQRLRELAPASKMVAVVKANAYGHGLLETARTLPDADAFGVARLEEALRLRAG 69 Query: 250 GLPLAIIEAKRTSKDPKAGTHQAKLYADCLERMTGRRPMMFTSNGFETNLWD-DVTSPQR 308 G+ ++ + T A+ + + + + V Sbjct: 70 GITKPVLLLEGFFDARDLPTISAQHFHTAVHN-----EEQLAALEEASLDEPVTVWMKLD 124 Query: 309 KVSGVFSK-SDLQKLMNRRNERKVLDEVV----------IDDNITDRYYQKEAIRAVCDN 357 + + R + + Q C+ Sbjct: 125 TGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHFARADEPKCGATEKQLAIFNTFCEG 184 Query: 358 IMTGHRRSLLVMATGTGKTRTASSLTDVLSRGGYVTNILFLADRKALVKQAK-DDFKNYL 416 + ++ ++ G + Sbjct: 185 KPGQRSIAASGGILLWPQSHFDWVRPGIILYGVSPLEDRSTGADFGCQPVMSLTSSLIAV 244 Query: 417 PDMSLCNLLSNKDDKTARIVFSTYPTMLNAIDRAKSDDGKRLFTPAHFDLIIVDEAHRSI 476 + T T ++ D R L+ E Sbjct: 245 REHK--AGEPVGYGGTWVSERDTRLGVVA---MGYGDGYPRAAPSGTPVLVNGREVPIVG 299 Query: 477 FKK---FRAIFEYFDGYV-VGLTATPKTDVDRNTYDFFEMESGVPTYAYPYETAVEMDRV 532 + + Sbjct: 300 RVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERIAEM----TKVSAYELITRLTS-RVA 354 Query: 533 LVPYHNIEVTTKVLEQGITYDTLSADDKARYEEDFTEEDGEMPEFIPSPA--------IN 584 Sbjct: 355 --------------------------- 387 Query: 585 DFIFNQATVDQVL-----EDLMTQGIK--VSGGDRLGKTIIFAQNKNHAQY----IVERF 633 Sbjct: 388 447 Query: 634 NKLYPQYKGDFAKRIVSEDDYTQSLIDDF-KLANKSPYIAVSVDMLDTGIDVPEIVNLVF 692 Sbjct: 448 - 506 Query: 693 FKRIRSKTKFWQMIGRGTRLCKDLFGEGEDKTHFVIFDYLGNFEFF 738 Sbjct: 507 ----- 547 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.137 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 80,786,498 Number of extensions: 3493000 Number of successful extensions: 7867 Number of sequences better than 1.0e-05: 15 Number of HSP's gapped: 7814 Number of HSP's successfully gapped: 15 Length of query: 1115 Length of database: 38,378,431 Length adjustment: 117 Effective length of query: 998 Effective length of database: 24,884,353 Effective search space: 24834584294 Effective search space used: 24834584294 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 121 (51.2 bits)