BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0342.0011.p (471 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_yqjI [G] COG0362 6-phosphogluconate dehydrogenase 639 0.0 BS_gntZ [G] COG0362 6-phosphogluconate dehydrogenase 545 e-155 YGR256w [G] COG0362 6-phosphogluconate dehydrogenase 534 e-152 YHR183w [G] COG0362 6-phosphogluconate dehydrogenase 506 e-143 STM0438 [R] COG0790 FOG: TPR repeat, SEL1 subfamily 464 e-130 >BS_yqjI [G] COG0362 6-phosphogluconate dehydrogenase Length = 207 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 0/405 (0%), Positives = 0/405 (0%) Query: 64 LETPRKIMIMVKAGKPTDDTIQQLVPHLSPGDILIDGGNAFFPDTQRRNKELQAQGFRFI 123 + + + + + + + + Q F Sbjct: 1 MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCGGRHGRGGGRRQRFFGH 60 Query: 124 GAGVSGGEEGALKGPAIMPGGQKDAYELVEPILTAISAKVDGDPCSTYIGEDGAGHYVKM 183 G + + + K L + T + + Sbjct: 61 GELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYPTLDFLQEQSLITIREEEG 120 Query: 184 VHNGIEYGDMQLIGEAYQLLKDVLGLDTAELHEIFSEWNRGELSSYLIEITADIFAKADP 243 I + + + + + + + + ++ + Sbjct: 121 GKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQNPQMKRALDNFKAVLDLRVN 180 Query: 244 DTGKPMVDVILDSAGQKGTGKWTSQNALDLGVPLSIITESVFARFISAMKEERVAASKRL 303 Sbjct: 181 240 Query: 304 KGPAVKGYDGDAKEFIEAVRKALYASKIASYAQGFAQMRVASDEYNWNLNYGSIAMIFRG 363 Sbjct: 241 300 Query: 364 GCIIRAGFLQNIKDAYDRDPELKNLFLDEYFSSVVHNYQEAWRDVVALAVKRGIPVPAFA 423 Sbjct: 301 360 Query: 424 SGLAYYDSYRSERLPANLLQAQRDYFGAHTFERLDQPGSFHFQWM 468 Sbjct: 361 405 >BS_gntZ [G] COG0362 6-phosphogluconate dehydrogenase Length = 468 Score = 545 bits (1403), Expect = e-155, Method: Compositional matrix adjust. Identities = 257/462 (55%), Positives = 326/462 (70%) Query: 6 IGVVGLAVMGKNLALNMESKGFSVALYNRSREKTDELLAEAAGKNFTGAYSIEEFVQSLE 65 IGV+GL VMG N+ALNM +KG +VA+YN +R+ TD+L+ + G++ + Y +E+FVQSLE Sbjct: 5 IGVIGLGVMGSNIALNMANKGENVAVYNYTRDLTDQLIQKLDGQSLSPYYELEDFVQSLE 64 Query: 66 TPRKIMIMVKAGKPTDDTIQQLVPHLSPGDILIDGGNAFFPDTQRRNKELQAQGFRFIGA 125 PRKI +MV AGKP D IQ L P L GD+++DGGN+ + DT+RR EL+ +G ++G Sbjct: 65 KPRKIFLMVTAGKPVDSVIQSLKPLLEEGDVIMDGGNSHYEDTERRYDELKEKGIGYLGV 124 Query: 126 GVSGGEEGALKGPAIMPGGQKDAYELVEPILTAISAKVDGDPCSTYIGEDGAGHYVKMVH 185 G+SGGE GAL GP+IMPGG +D YE PILT I+A+V DPC YIG GAGH+ KMVH Sbjct: 125 GISGGEVGALTGPSIMPGGDRDVYEKAAPILTKIAAQVGDDPCCVYIGPKGAGHFTKMVH 184 Query: 186 NGIEYGDMQLIGEAYQLLKDVLGLDTAELHEIFSEWNRGELSSYLIEITADIFAKADPDT 245 NGIEY DMQLI EAY L++ L L E+ IF WN+GEL SYLIEITA+I K D T Sbjct: 185 NGIEYADMQLIAEAYTFLRETLRLPLDEIASIFETWNQGELKSYLIEITAEILRKKDEKT 244 Query: 246 GKPMVDVILDSAGQKGTGKWTSQNALDLGVPLSIITESVFARFISAMKEERVAASKRLKG 305 G+P++DVILD GQKGTGKWTS A+D G+P +IITES+FAR++S++KEER+AA L G Sbjct: 245 GQPLIDVILDKTGQKGTGKWTSMQAIDNGIPSTIITESLFARYLSSLKEERMAAQDVLAG 304 Query: 306 PAVKGYDGDAKEFIEAVRKALYASKIASYAQGFAQMRVASDEYNWNLNYGSIAMIFRGGC 365 P + D +IE VR+ALY K+ +YAQGFAQ +++S+ Y WNL IA+IFRGGC Sbjct: 305 PEAEEKHLDKDTWIEYVRQALYMGKVCAYAQGFAQYKMSSELYGWNLPLKDIALIFRGGC 364 Query: 366 IIRAGFLQNIKDAYDRDPELKNLFLDEYFSSVVHNYQEAWRDVVALAVKRGIPVPAFASG 425 IIRA FL I +A+ P L NL + YF+ +H YQ R VV + GI P + Sbjct: 365 IIRADFLNVISEAFSEQPNLANLLIAPYFTDKLHAYQTGLRKVVCEGISTGISFPCLTTA 424 Query: 426 LAYYDSYRSERLPANLLQAQRDYFGAHTFERLDQPGSFHFQW 467 L+YYD YR+ R ANLLQAQRDYFGAHT+ER D G FH W Sbjct: 425 LSYYDGYRTGRSNANLLQAQRDYFGAHTYERTDMDGVFHTNW 466 >YGR256w [G] COG0362 6-phosphogluconate dehydrogenase Length = 492 Score = 534 bits (1376), Expect = e-152, Method: Compositional matrix adjust. Identities = 261/462 (56%), Positives = 336/462 (72%), Gaps = 3/462 (0%) Query: 6 IGVVGLAVMGKNLALNMESKGFSVALYNRSREKTDELLA-EAAGKNFTGAYSIEEFVQSL 64 +G+VGLAVMG+NL LN GF+V YNR++ K D LA EA GK+ GA SIE+ V L Sbjct: 8 LGLVGLAVMGQNLILNAADHGFTVVAYNRTQSKVDRFLANEAKGKSIIGATSIEDLVAKL 67 Query: 65 ETPRKIMIMVKAGKPTDDTIQQLVPHLSPGDILIDGGNAFFPDTQRRNKELQAQGFRFIG 124 + PRKIM+++KAG P D I++LVPHL GDI+IDGGN+ FPDT RR +EL QG F+G Sbjct: 68 KKPRKIMLLIKAGAPVDTLIKELVPHLDKGDIIIDGGNSHFPDTNRRYEELTKQGILFVG 127 Query: 125 AGVSGGEEGALKGPAIMPGGQKDAYELVEPILTAISAKVDGDPCSTYIGEDGAGHYVKMV 184 +GVSGGE+GA GP++MPGG +A+ ++ I +I+AK +G+PC ++G G+GHYVKMV Sbjct: 128 SGVSGGEDGARFGPSLMPGGSAEAWPHIKNIFQSIAAKSNGEPCCEWVGPAGSGHYVKMV 187 Query: 185 HNGIEYGDMQLIGEAYQLLKDVLGLDTAELHEIFSEWNRGELSSYLIEITADIFAKADPD 244 HNGIEYGDMQLI EAY ++K + E+ E+F +WN G L S+LIEIT DI D D Sbjct: 188 HNGIEYGDMQLICEAYDIMKRIGRFTDKEISEVFDKWNTGVLDSFLIEITRDILKFDDVD 247 Query: 245 TGKPMVDVILDSAGQKGTGKWTSQNALDLGVPLSIITESVFARFISAMKEERVAASKRLK 304 GKP+V+ I+D+AGQKGTGKWT+ NALDLG+P+++I E+VFAR +SA+K+ER ASK L Sbjct: 248 -GKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSAIKDERKRASKLLA 306 Query: 305 GPAV-KGYDGDAKEFIEAVRKALYASKIASYAQGFAQMRVASDEYNWNLNYGSIAMIFRG 363 GP V K D ++F+ + +ALYASKI SYAQGF +R A+ Y W LN +IA+++RG Sbjct: 307 GPTVPKDAIHDREQFVYDLEQALYASKIISYAQGFMLIREAARSYGWKLNNPAIALMWRG 366 Query: 364 GCIIRAGFLQNIKDAYDRDPELKNLFLDEYFSSVVHNYQEAWRDVVALAVKRGIPVPAFA 423 GCIIR+ FL I AY DP+L+NL +E+F+S V Q WR +ALA GIP PAF+ Sbjct: 367 GCIIRSVFLAEITKAYRDDPDLENLLFNEFFASAVTKAQSGWRRTIALAATYGIPTPAFS 426 Query: 424 SGLAYYDSYRSERLPANLLQAQRDYFGAHTFERLDQPGSFHF 465 + LA+YD YRSERLPANLLQAQRDYFGAHTF L + S H Sbjct: 427 TALAFYDGYRSERLPANLLQAQRDYFGAHTFRILPECASAHL 468 >YHR183w [G] COG0362 6-phosphogluconate dehydrogenase Length = 489 Score = 506 bits (1302), Expect = e-143, Method: Compositional matrix adjust. Identities = 257/471 (54%), Positives = 339/471 (71%), Gaps = 11/471 (2%) Query: 7 GVVGLAVMGKNLALNMESKGFSVALYNRSREKTDELLA-EAAGKNFTGAYSIEEFVQSLE 65 G++GLAVMG+NL LN GF+V YNR++ K D LA EA GK+ GA SIE+F+ L+ Sbjct: 6 GLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLK 65 Query: 66 TPRKIMIMVKAGKPTDDTIQQLVPHLSPGDILIDGGNAFFPDTQRRNKELQAQGFRFIGA 125 PRK+M++VKAG P D I Q+VP L GDI+IDGGN+ FPD+ RR +EL+ +G F+G+ Sbjct: 66 RPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGS 125 Query: 126 GVSGGEEGALKGPAIMPGGQKDAYELVEPILTAISAKVDGDPCSTYIGEDGAGHYVKMVH 185 GVSGGEEGA GP++MPGG ++A+ ++ I +ISAK DG+PC ++G GAGHYVKMVH Sbjct: 126 GVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGHYVKMVH 185 Query: 186 NGIEYGDMQLIGEAYQLLKDVLGLDTAELHEIFSEWNRGELSSYLIEITADIFAKADPDT 245 NGIEYGDMQLI EAY ++K + G E+ ++F++WN G L S+L+EIT DI D D Sbjct: 186 NGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFDDVD- 244 Query: 246 GKPMVDVILDSAGQKGTGKWTSQNALDLGVPLSIITESVFARFISAMKEERVAASKRLKG 305 GKP+V+ I+D+AGQKGTGKWT+ NALDLG+P+++I E+VFAR +SA+K ER+ ASK L G Sbjct: 245 GKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPG 304 Query: 306 PAV-KGYDGDAKEFIEAVRKALYASKIASYAQGFAQMRVASDEYNWNLNYGSIAMIFRGG 364 P V K D ++F++ + +ALYASKI SYAQGF +R A+ Y W LN +IA+++RGG Sbjct: 305 PEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGG 364 Query: 365 CIIRAGFLQNIKDAYDRDPELKNLFLDEYFSSVVHNYQEAWRDVVALAVKRGIPVPAFAS 424 CIIR+ FL I AY +P+L+NL +++F+ V Q WR +ALA GIP PAF++ Sbjct: 365 CIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFST 424 Query: 425 GLAYYDSYRSERLPANLLQAQRDYFGAHTFERLDQPGS--------FHFQW 467 L++YD YRSERLPANLLQAQRDYFGAHTF L + S H W Sbjct: 425 ALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINW 475 >STM0438 [R] COG0790 FOG: TPR repeat, SEL1 subfamily Length = 673 Score = 464 bits (1193), Expect = e-130, Method: Compositional matrix adjust. Identities = 38/468 (8%), Positives = 91/468 (19%), Gaps = 9/468 (1%) Query: 3 KQQIGVVGLAVMGKNLALNMESKGFSVALYNRSREKTDELLA-EAAGKNFTGAYSIEEFV 61 + G L + G ++ A ++ + Sbjct: 2 RLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAR 61 Query: 62 QSLETPRKIMIMVKAGKPTDDTIQQLVPHLSPGDILIDGGNAFFPDTQRRNKELQAQGFR 121 + E + + +A T L + + G A F ++ + Sbjct: 62 EMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALLKELT 121 Query: 122 FIGAGVSGGEEGALKGPAIMPGGQKDAYELVEPILTAISAKVDGDPCSTYIGEDGAGHYV 181 L ++ Y A + + Sbjct: 122 EGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGERDRIFAHCYGLYDAHLKACNVL 181 Query: 182 KMVHNGIEYGDMQLIGEAYQLLKDVLGLDTAELHEIFSEWNRGELSSYLIEITADIFAKA 241 + + E + + ++ EL L+ A Sbjct: 182 DFDDLILLPTLLLQANEEVRKRWQNKIRYLLVDEYQDTNTSQYELVKLLVGSRARFTVVG 241 Query: 242 DPDTGKPMVDVILDSAGQKGTGKWTSQNALDLGVPLSIITESVFARFISAMKEERVAASK 301 D D + + + + L + A I V + Sbjct: 242 DDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQNYRSSGRILKAANILIANNPHVFEKR 301 Query: 302 --RLKGPAVKGYDGDAKEFIEAVRKALYASKIASYAQGFAQMRVASDEYNWNLNYGSIAM 359 G + A F D + Sbjct: 302 LFSELGYGAEL----KVLSANNEEHEAERVTGELIAHHFVNKTQYKDYAILYRGNHQSRV 357 Query: 360 IFRGGCIIRAGFLQNIKDAYDRDPELKNLFLDEYFSSVVHNYQEAWRDVVALAVKRGIPV 419 + R + + ++ + L Y + + ++ + KR I Sbjct: 358 FEKFLMQNRIPYKISGGTSFFS--RPEIKDLLAYLRVLTNPDDDSAFLRIVNTPKREIGP 415 Query: 420 PAFASGLAYYDSYRSERLPANLLQAQRDYFGAHTFERLDQPGSFHFQW 467 + + A+ +E L + + + Sbjct: 416 ATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGYEALTRFTHWLAEI 463 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,222,609 Number of extensions: 1704851 Number of successful extensions: 3464 Number of sequences better than 1.0e-05: 40 Number of HSP's gapped: 3440 Number of HSP's successfully gapped: 40 Length of query: 471 Length of database: 38,378,431 Length adjustment: 110 Effective length of query: 361 Effective length of database: 25,691,691 Effective search space: 9274700451 Effective search space used: 9274700451 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)