BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0341.0026.p (548 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH2109 [T] COG4753 Response regulator containing CheY-like recei... 139 1e-32 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 124 5e-28 BH3842 [T] COG4753 Response regulator containing CheY-like recei... 124 5e-28 SPy1556 [T] COG4753 Response regulator containing CheY-like rece... 98 3e-20 BH1123 [T] COG4753 Response regulator containing CheY-like recei... 98 4e-20 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 139 bits (350), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 138/570 (24%), Positives = 259/570 (45%), Gaps = 80/570 (14%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MYKVL+ DDE +R + L +W+ G + EA +G +++++ K DL + D++MP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 LNGSQLLQ-IAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKA 119 +G QL+Q + E + I+ISGYNDF Y ++A+R VD++LKP+++ +L +AL K Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 MDVLEAKRKRESEFITRNITLNMSLPKLKEKMYLSIIERSFKNQSNEAFLPLIGADKPGN 179 L+ ++ S+ +EK+ L ++ F+ +G +K N Sbjct: 121 AATLDQEKATNSD---------------QEKVLL-----------DQIFIHSLGENKKEN 154 Query: 180 HFAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNV------INENSGGHFEAF---SFASP 230 + LN+ RH ++ L V N+ INE + A Sbjct: 155 EVRRWAAK-LNINN-RHFYYY-----LLLEVNNLSLDKGFINEQYKEPIRKVIRETVARQ 207 Query: 231 RSEREFIAIF-TLKGSYGEDAAFLSLHHMK-----------KTVSTLKELFGILCAGGLG 278 + E+ AI+ L +YG ++ H+K K +++ I +G Sbjct: 208 AATEEYTAIYEQLDHAYG---LLITSEHLKKFNGQIEPLAEKLRKDIQDFTNIPLTVYVG 264 Query: 279 QPYSEVMGIAQSYELAKAALDGTDLLTLKGSTVSNSGYTKSAAKDSPSLTGRMPL-IRSS 337 ++ I +SYE A + + + K + T+S L + + + Sbjct: 265 AKTDDLSTIKKSYETANSLRNYKYIFNEKNVFIHEQ--TESVDTTYDELNNHLFVTLMEQ 322 Query: 338 LESGNAGHAKSIL----SDF-TRKW-KSSEHFSLGEA-DRIIQEFIILLGDIAVELDAVP 390 +E N+ +I+ S+F T+K+ S+ S+ +++Q + GD + A Sbjct: 323 MEENNSDRIVNIIDKIFSEFQTKKFVPSAVKTSVNRCVHKVMQTVQAMEGDTGKIISA-- 380 Query: 391 ERLRSGKSKGLRGLGISSDFASFGEFEAVLSSILDVYAGEISRSLAGDRSSVLENIKAYI 450 + + + +S L +F + + V + + A I + S + +K YI Sbjct: 381 QAMTNWESYNL----------TFDQLKQVFTKFVLEAAVIIQELRKENMKSDIYKVKTYI 430 Query: 451 DNHYFENIKISMFTDKYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKELLSDPALKIQ 510 +NHY ENI + ++++ Y+ +LFK +G EY+ K+RM++AK+LL +++ Sbjct: 431 ENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYLLKLRMNEAKKLLRQTDMRVY 490 Query: 511 DISERLGYKDKNYFSKAFRNYYDCSPSEFR 540 +++ER+G+ +YF F +P+E+R Sbjct: 491 EVAERVGFGSTDYFVTQFEKINKMTPTEYR 520 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 124 bits (311), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 135/545 (24%), Positives = 232/545 (42%), Gaps = 55/545 (10%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MY V+I+DDE +RE + L W+ G + A +G+ G R+ DL +VD++MPE Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 ++G L++ E + I++SG++DF Y ++A+ + DYLLKP++ +L +L+K Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 121 DVLEAKRKRESEFITRNITLNMSLPKLKEKMYLSIIERSFKNQSNEAFLPLIGADKPGNH 180 ITR+ ++ + +++EK ++ + L I K N Sbjct: 121 GR-----------ITRHHQVHELVERVQEKQVEMVLTELLEGTP----LSEIPIGKEHNF 165 Query: 181 FAVGVLRMLNVEQVRHARFHEDRDLLHFAVTNVINENSGGHFEAFSFASPRSEREFIAIF 240 FA QV +DR L + +I E G+ F E+I I Sbjct: 166 FATDY-------QVALVENRQDR--LTKQLKRLIEEQEEGYVIPFP--------EYIVI- 207 Query: 241 TLKGSYGEDAAFLSLHHMKKTVSTLKELFGILCAGGLGQPYSEVMGIAQSYELAKAA--L 298 K + + +H+ +EL CAG S+V+ +A YE ++A L Sbjct: 208 VCKNRFLQKRGKDHRYHLFAKWLEEEELHA--CAG------SKVVNLADIYESYQSAKRL 259 Query: 299 DGTDLLTLKGSTVSNSGYTKSAAKDSP--SLTGRMPLIRSSLESGNAGHAKSILSDFTRK 356 KG + + ++P SL + S++ GN +I+ + Sbjct: 260 YEKKFFVEKGRLFTADQLVDRSKPEAPEFSLESYADRLYYSIDIGNMEGCVAIIEEL--- 316 Query: 357 WKSSEHFSLGEADRIIQEFIILLGDIAVELDAVPERLRSGKSKGLRGLGISS-DFASFGE 415 K+ L E I L +I +L R L L +++ D F Sbjct: 317 -KNVVIVHLQEEKEIKVALFQLYSNILHQL----VRSHPNMEGVLEPLVMNAGDIYQFEH 371 Query: 416 FEAVLSSILDVYAGEISRSLAGDRSSVLENIKAYIDNHYFENIKISMFTDKYFLSREYLM 475 +++ + I G +L + A I Y +N+++ + +R YL Sbjct: 372 LPGIMAFLTKQLKYVIDCMDNGQPDLLLRKMIALIHKDYAKNLRLETLASVFNYNRAYLG 431 Query: 476 KLFKGQYGYGIHEYVQKVRMDKAKELLSDPALKIQDISERLGYKDKNYFSKAFRNYYDCS 535 KLFK G + Y+ KVR++ K LL K+ +++E++GY + +YF + F+ Y S Sbjct: 432 KLFKNYTGEYFNTYLDKVRIENGKRLLQ-KGYKVYEVAEKIGYANVDYFHRKFKKYVGVS 490 Query: 536 PSEFR 540 PS FR Sbjct: 491 PSTFR 495 >BH3842 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 530 Score = 124 bits (310), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 137/574 (23%), Positives = 246/574 (42%), Gaps = 94/574 (16%) Query: 1 MYKVLIIDDEEPLREAIHI-LGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMP 59 M VLI+DDE+ RE + + L D + + V EA++GR +E + + DL ++D+KMP Sbjct: 1 MINVLIVDDEQIEREGLKLFLKDRPNIHI--VGEASNGRQAIEKALETQPDLMMMDIKMP 58 Query: 60 ELNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKA 119 ++G Q ++ +++ P+ I++S ++ FEY R+ +R V +YLLKP + D+ +AL + Sbjct: 59 GVDGVQAVKEIKQQLPETEFIMVSAFDTFEYAREVMRYGVKEYLLKPTTKEDVLTALDRI 118 Query: 120 MDVLEAKRKRE-------------SEFITRNITLNMSLPKLKEKMYLSIIERSFKNQSNE 166 + +E R+ + S F+ L + + +++ ++ E + E Sbjct: 119 VGEIEQAREEKNDQYKLQQRLEQISSFVQTESILYLLMDHIQDYEWMEWNE--WLRTEQE 176 Query: 167 AFLPLIGADKPGNHFAVGVLRMLNVEQVRHARFHEDRDLL-----------HFAVTNVIN 215 + + + G +R +Q HAR ++ L H ++ Sbjct: 177 GYAVVFSFHQQGKE-----IRKTEKQQW-HARIKKEIGLQLPKSTVGPFIGHHLPILMLT 230 Query: 216 ENSGGHFEAFSFASPRSEREFIAIFTLKGSYGEDAAFLSLHHMKKTVSTLKELFGILCAG 275 EN G + ERE + I LH +K+ V K Sbjct: 231 ENENG--------MTKQEREQVVIQL-------------LHKVKQAVQPAK------VKT 263 Query: 276 GLGQPYSEVMGIAQSYELAKAALDGTDLLTLKGSTVSNSGYTKSAAKDSPSLTGRMPLIR 335 G+G Y + + SY A ALD + S Y K+ + ++P+ R Sbjct: 264 GVGGIYR-LHFFSTSYREALLALD----IIYDHKQASYYFYDKNVKIRADE---QLPIER 315 Query: 336 -----SSLESGNAGHAKSILSDFTRKWKSSEHFSLGEADRIIQEFIILLGDIAVELDAVP 390 +++SG+ A + + L + + +Q+ I+LG + E+ Sbjct: 316 ENKLIEAIKSGDGEKALQAFDHYVQAILRCSKHPLHDMRKYLQQLFIILGRLLNEM---- 371 Query: 391 ERLRSGKSKGLRGLGISSDFASFGEFEAVL----SSILDVYAGEISRSLAGDRSSVLENI 446 GL + DFA F V S IL + + D S++ Sbjct: 372 ---------GLH-WETAQDFARFSTVHQVTEHGKSEILHI-VRTLQEWRTTDEQSLMLLA 420 Query: 447 KAYIDNHYFENIKISMFTDKYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKELLSDPA 506 + Y+ +H+ E + + LS Y+ KLFK ++ EYV ++R++ AK+LLS Sbjct: 421 RDYVHDHFREPLTLDDLAKHIGLSPYYVSKLFKERFDLTFSEYVTQLRVEHAKQLLSLTQ 480 Query: 507 LKIQDISERLGYKDKNYFSKAFRNYYDCSPSEFR 540 +++I+ +GYKD NYFS+ F+ SPS++R Sbjct: 481 KSLKEITYEIGYKDPNYFSRVFKKLTGKSPSDYR 514 >SPy1556 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 246 Score = 98.2 bits (243), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 48/131 (36%), Positives = 81/131 (61%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 MY +LI++DE +R+ I L D+ +D+V EA +G++ ++ +K D+ L D+ MP+ Sbjct: 1 MYSLLIVEDEYLVRQGIRSLVDFSQFKIDRVNEAENGQLAWDLFQKEPYDIVLTDINMPK 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 LNG QL ++ ++E P L+ ++GY+DF Y A++ DYLLKP +++D+ L K Sbjct: 61 LNGIQLAELIKQESPQTHLVFLTGYDDFNYALSALKLGADDYLLKPFSKADVEDMLGKLR 120 Query: 121 DVLEAKRKRES 131 LE +K E+ Sbjct: 121 KKLELSKKTET 131 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 97.8 bits (242), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 55/186 (29%), Positives = 103/186 (55%), Gaps = 1/186 (0%) Query: 1 MYKVLIIDDEEPLREAIHILGDWKGLGVDQVLEATDGRVGLEMLRKHKIDLALVDMKMPE 60 M+KV+IIDDEE + + + WK LG + V EA +GR GL+++R+ + L D+ MP Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 LNGSQLLQIAEREFPDLLLIVISGYNDFEYTRQAIRSKVVDYLLKPVNRSDLNSALRKAM 120 + G ++QI + D ++++SGY++FE+ R+A++ + DYL KP + + + L++ + Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 DVLEAKRKRESEFITRNITLNMSLPKLKEKMYLSIIERSFKN-QSNEAFLPLIGADKPGN 179 + LE K++++ + P ++ + S++ +N + E FL I K Sbjct: 121 NKLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKITKWKDQQ 180 Query: 180 HFAVGV 185 H A + Sbjct: 181 HIACSL 186 Score = 70.9 bits (172), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 58/99 (58%) Query: 441 SVLENIKAYIDNHYFENIKISMFTDKYFLSREYLMKLFKGQYGYGIHEYVQKVRMDKAKE 500 ++E + YI+ H ENI + D+ ++SR YL ++FK G YV ++RM+KAK+ Sbjct: 424 QLIEQVMIYIEKHLAENITLQDIADELYISRNYLGQIFKKVVGESFKNYVTRLRMEKAKK 483 Query: 501 LLSDPALKIQDISERLGYKDKNYFSKAFRNYYDCSPSEF 539 ++ + I ++SE++GY + YF+ F+ Y +P + Sbjct: 484 MIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYTGYTPRDL 522 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 39,275,707 Number of extensions: 1686256 Number of successful extensions: 5022 Number of sequences better than 1.0e-05: 184 Number of HSP's gapped: 5191 Number of HSP's successfully gapped: 194 Length of query: 548 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 437 Effective length of database: 25,576,357 Effective search space: 11176868009 Effective search space used: 11176868009 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 118 (50.1 bits)