BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0340.0031.p
         (161 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

VC1217 [KR] COG0454 Histone acetyltransferase HPA2 and related a...   113   2e-25
YPO3444 [KR] COG0454 Histone acetyltransferase HPA2 and related ...   103   1e-22
Z5868 [KR] COG0454 Histone acetyltransferase HPA2 and related ac...    60   1e-09
MA1191 [KR] COG0454 Histone acetyltransferase HPA2 and related a...    58   7e-09

>VC1217 [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 161

 Score =  113 bits (282), Expect = 2e-25,   Method: Compositional matrix adjust.
 Identities = 63/163 (38%), Positives = 95/163 (58%), Gaps = 7/163 (4%)

Query: 1   MNIRLIEYKD--NSSIEHIIRVCLIEFGGNREGLAWADASMHDLYHYYKEPNR-AYWIVE 57
           M + ++  +   ++ I  II+    EFG   EG   +DA +  +  YY+E +R AY++  
Sbjct: 1   MRVEIVPIRPEFDAEICQIIQSVGAEFGAIGEGFGPSDAEVLAMSQYYREQDRSAYFVAL 60

Query: 58  EDGKVLGGCGIAPFAESDQVCELQKMYLSTSIRGSGIAVELLQTALDFAALH-YKQCYLE 116
            +GKV+GG GIAPFA    +CEL+K++L  + RG G+   L +  L+FA    Y +CYL+
Sbjct: 61  LEGKVVGGGGIAPFAGHTDLCELKKLFLLPTSRGHGVGRALSEHCLNFAKQQGYTKCYLD 120

Query: 117 TLQSMHAANRFYRKNGFTLLXXXXSPLGGSEHFACDAWYIKSL 159
           TL SM  A + Y++ GF  L     P+ G+EH  CD W +KSL
Sbjct: 121 TLSSMTQAIKLYQQLGFEHL---TQPMAGTEHNGCDVWMLKSL 160


>YPO3444 [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 167

 Score =  103 bits (256), Expect = 1e-22,   Method: Compositional matrix adjust.
 Identities = 60/161 (37%), Positives = 89/161 (55%), Gaps = 8/161 (4%)

Query: 3   IRLIEYKDNSSIEHIIRVCLIEFGGNRE-GLAWADASMHDLYHYYKEPNRAYWIVEEDGK 61
           +R I   DN +I ++IR    EFG   + G   +D ++  LY  Y +P  AYW++E DG 
Sbjct: 11  VRPITAGDNLAIANVIREVSAEFGLTADKGYTVSDPNLDHLYELYSQPRSAYWVIEVDGH 70

Query: 62  VLGGCGIAPF--AESDQVCELQKMYLSTSIRGSGIAVELLQTALDFAALH-YKQCYLETL 118
           + GG G+AP    E+D +CELQKMY    +RG G+A +L   AL FA    + +CYLET 
Sbjct: 71  IAGGGGVAPLLGGEAD-LCELQKMYFLPILRGKGLAKQLALQALAFARQQGFGRCYLETT 129

Query: 119 QSMHAANRFYRKNGFTLLXXXXSPLGGSEHFACDAWYIKSL 159
            S+ +A   Y + GF  +      +G + H  C+   +K+L
Sbjct: 130 ASLTSAVGLYERLGFEHI---GGAMGNTGHVDCEVTMLKTL 167


>Z5868 [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 97

 Score = 60.5 bits (145), Expect = 1e-09,   Method: Compositional matrix adjust.
 Identities = 38/100 (38%), Positives = 56/100 (56%), Gaps = 5/100 (5%)

Query: 62  VLGGCGIAPFAESDQ-VCELQKMYLSTSIRGSGIAVELLQTALDFA-ALHYKQCYLETLQ 119
           ++GG GIAP A S+  +CELQKMY   +IRG G+A +L   A++ A  + +K+CYLET  
Sbjct: 1   MVGGGGIAPLAGSESDICELQKMYFLPAIRGKGLAKKLALKAMEEAREMGFKRCYLETTA 60

Query: 120 SMHAANRFYRKNGFTLLXXXXSPLGGSEHFACDAWYIKSL 159
            +  A   Y   GF  +      LG + H  C+   ++ L
Sbjct: 61  FLKEAIGLYEHLGFQHIDY---ALGCTGHVDCEVRMLREL 97


>MA1191 [KR] COG0454 Histone acetyltransferase HPA2 and related
           acetyltransferases
          Length = 145

 Score = 57.8 bits (138), Expect = 7e-09,   Method: Compositional matrix adjust.
 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 2/101 (1%)

Query: 36  DASMHDLYHYYKEPNRAYWIVEEDGKVLGGCGIAPFAESDQVCELQKMYLSTSIRGSGIA 95
           D+ ++D+  YY      +++   DG+V+G  G+       + CE++++YL  + RG G  
Sbjct: 34  DSDLNDINGYYFAKGGTFFVGLADGRVVGTAGVRKL--EGKRCEIRRIYLKENFRGKGNG 91

Query: 96  VELLQTALDFAALHYKQCYLETLQSMHAANRFYRKNGFTLL 136
            +L   ALDFA  +     L+T  ++  A   Y K+GFT L
Sbjct: 92  KKLFLAALDFAEKNCSGVVLKTDSTLKKAIGMYLKHGFTFL 132


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.322    0.137    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 11,586,260
Number of extensions: 447597
Number of successful extensions: 637
Number of sequences better than 1.0e-05: 5
Number of HSP's gapped: 639
Number of HSP's successfully gapped: 5
Length of query: 161
Length of database: 38,378,431
Length adjustment: 98
Effective length of query: 63
Effective length of database: 27,075,699
Effective search space: 1705769037
Effective search space used: 1705769037
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 111 (47.4 bits)