BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0340.0019.p
         (174 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CAC0829 [V] COG4767 Glycopeptide antibiotics resistance protein        65   7e-11
lin1455 [V] COG4767 Glycopeptide antibiotics resistance protein        56   3e-08
lin0486 [V] COG4767 Glycopeptide antibiotics resistance protein        52   6e-07
BH3967 [V] COG4767 Glycopeptide antibiotics resistance protein         49   3e-06
Cgl2953 [V] COG4767 Glycopeptide antibiotics resistance protein        49   6e-06

>CAC0829 [V] COG4767 Glycopeptide antibiotics resistance protein
          Length = 308

 Score = 64.7 bits (156), Expect = 7e-11,   Method: Compositional matrix adjust.
 Identities = 49/143 (34%), Positives = 73/143 (51%), Gaps = 20/143 (13%)

Query: 19  VYLYVLIKIILFKYAPVDIAFLWRQLHSVLEHPARIRYGLAFANFTPFVSISR---NLHQ 75
           +Y+  L KIILFK     I+FL  Q+         I       N  PF SI +      +
Sbjct: 21  IYIIALFKIILFK----SISFL--QIFKGYNKSRSI-------NLIPFKSIIQFIDTYKE 67

Query: 76  LSNPHDFVNLFGNIALFVPLGIFIRLLAK--GGLFTALVLSFGISFSLEGTQLLLSMGSF 133
           + +   F NL GN+ +F+P G  +  L K    + + ++ SFG+S   E TQ +L +GS 
Sbjct: 68  MGSFRAFANLAGNLIVFMPFGYLVPTLNKRFSRIRSTVIASFGLSLFFEVTQYVLEIGSS 127

Query: 134 DVDDLILNVFGGLLGY--IICLK 154
           D+DD+ILN  G + GY  + CL+
Sbjct: 128 DIDDIILNTLGAVAGYSVLTCLR 150


>lin1455 [V] COG4767 Glycopeptide antibiotics resistance protein
          Length = 199

 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 34/80 (42%), Positives = 51/80 (63%), Gaps = 4/80 (5%)

Query: 87  GNIALFVPLGIFIRLLAKGGLFTALVLSFGISFSLEGTQLLLSMGSFDVDDLILNVFGGL 146
           GN+  FVP+G    LL K G FTAL+ +  + F++EG Q ++ +G FD  D+ LNV G +
Sbjct: 120 GNVLAFVPIGF---LLKKLGFFTALLSAGMLIFAVEGMQYIMHVGFFDTGDVFLNVCGIM 176

Query: 147 LGYI-ICLKNPRKHGKTQLQ 165
           LGYI I   +PRK  + +++
Sbjct: 177 LGYILIRFLSPRKFKRFKVK 196


>lin0486 [V] COG4767 Glycopeptide antibiotics resistance protein
          Length = 181

 Score = 51.6 bits (122), Expect = 6e-07,   Method: Compositional matrix adjust.
 Identities = 32/99 (32%), Positives = 52/99 (52%), Gaps = 6/99 (6%)

Query: 59  AFANFTPFVSISRNLHQLSNPHDFVNLFGNIALFVPLGIFIRLLAKGGLFTALVLSFGIS 118
           A+    PF +I   L  + N H  +   GN+ L VP  I+I       +   +VL+ GIS
Sbjct: 68  AYLQIIPFQTILFYLKNIPNLHLMIQFLGNVVLLVPFAIYINRFKNISVLKNIVLALGIS 127

Query: 119 FSLEGTQLLLSMGS------FDVDDLILNVFGGLLGYII 151
             +E +Q +L++ +       D+DD+ILNV G +L ++I
Sbjct: 128 LIIEISQGILNLITQYPNNITDIDDVILNVSGYVLAWLI 166


>BH3967 [V] COG4767 Glycopeptide antibiotics resistance protein
          Length = 194

 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 29/69 (42%), Positives = 38/69 (55%), Gaps = 1/69 (1%)

Query: 84  NLFGNIALFVPLGIFIRLLAKGGLFTALVLSFGISFSLEGTQLLLSMGSFDVDDLILNVF 143
           N+  N  +FVPLG F+  + K  +F A       S  +E  Q +   G FD+DD+ILN  
Sbjct: 122 NIGANTLIFVPLG-FLLYIWKKNIFFAAQFCLYTSLLIEVVQFITRRGYFDIDDIILNTV 180

Query: 144 GGLLGYIIC 152
           GGLLG  IC
Sbjct: 181 GGLLGIFIC 189


>Cgl2953 [V] COG4767 Glycopeptide antibiotics resistance protein
          Length = 203

 Score = 48.5 bits (114), Expect = 6e-06,   Method: Compositional matrix adjust.
 Identities = 27/76 (35%), Positives = 41/76 (53%), Gaps = 5/76 (6%)

Query: 82  FVNLFGNIALFVPLGIFI-----RLLAKGGLFTALVLSFGISFSLEGTQLLLSMGSFDVD 136
           + N FGNIALF+P G F+     R   +      ++ +   S S+E  Q + ++G  DVD
Sbjct: 95  WTNTFGNIALFMPFGFFLYKMLRRFNHRFPFVETILFASVTSLSIEVLQWVFAIGYSDVD 154

Query: 137 DLILNVFGGLLGYIIC 152
           DL+ N  GGL+G  + 
Sbjct: 155 DLLFNTIGGLIGASVA 170


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.330    0.147    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 12,306,492
Number of extensions: 488682
Number of successful extensions: 1838
Number of sequences better than 1.0e-05: 8
Number of HSP's gapped: 1837
Number of HSP's successfully gapped: 8
Length of query: 174
Length of database: 38,378,431
Length adjustment: 99
Effective length of query: 75
Effective length of database: 26,960,365
Effective search space: 2022027375
Effective search space used: 2022027375
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.8 bits)
S2: 112 (47.8 bits)