BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0340.0016.p (353 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin2515 [T] COG0642 Signal transduction histidine kinase 182 6e-46 lin2727 [T] COG0642 Signal transduction histidine kinase 127 4e-29 CAC0317 [T] COG0642 Signal transduction histidine kinase 126 5e-29 lin1543 [T] COG0642 Signal transduction histidine kinase 123 5e-28 SA1322 [T] COG0642 Signal transduction histidine kinase 115 8e-26 >lin2515 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 182 bits (462), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 0/316 (0%), Positives = 0/316 (0%), Gaps = 36/316 (11%) Query: 53 FLILFVPLAIFFFF---LLTKR-YAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAE 108 + + I + + + + + +S ++ Sbjct: 83 RCRYELGVEITPPESIYPDFRYRATDPSGIVENEVCPVFAARTTSALQ-----INDDEVM 137 Query: 109 DINRASEQLQKAVERGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQV- 167 Sbjct: 138 -- 195 Query: 168 -KHYTMIAYTKSQRLEKLIEELFEITRVNYGMLAVVKAPIDLSELLFQL----------- 215 Sbjct: 196 255 Query: 216 NEELYPLFEKNKLTSRLQITPQMVIPADGELLARVFENLLTNAARYGRDGQFVDIHCRHE 275 Sbjct: 256 ---------- 305 Query: 276 GGSAVVQIINYGNFIPAEELPFLFDMFYTGDRARTSDANSTGLGLFIAKNIVEQHGGTIS 335 Sbjct: 306 -- 363 Query: 336 AESSVTRTLFEVRLPI 351 Sbjct: 364 379 >lin2727 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 127 bits (318), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 0/310 (0%), Positives = 0/310 (0%), Gaps = 14/310 (4%) Query: 46 RIGDVNFF---LILFVPLAIFFFFLLTKRY-AAYFDTISSGIHNLANGEFSSRVEITSHD 101 Sbjct: 157 AFSPWMVMQAT 216 Query: 102 EFQVIAEDINRASEQLQKAVERGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTD 161 Sbjct: 217 -------- 268 Query: 162 LTAEQVKHYTMIAYTKSQRLEKLIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEELYP 221 Sbjct: 269 328 Query: 222 LFEKNKLTSRLQITPQMVIPADGELLARVFENLLTNAARYGRDGQFVDIHCRHEGGSAVV 281 Sbjct: 329 - 387 Query: 282 QIINYGNFIPAEELPFLFDMFYTGDRARTSDANSTGLGLFIAKNIVEQHGGTISAESSVT 341 Sbjct: 388 447 Query: 342 R-TLFEVRLP 350 Sbjct: 448 457 >CAC0317 [T] COG0642 Signal transduction histidine kinase Length = 498 Score = 126 bits (317), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 80/293 (27%), Positives = 149/293 (50%), Gaps = 6/293 (2%) Query: 63 FFFFLLTKRYAAYFDTISSGIHNLANGEFSSRVEITSHDEFQVIAEDINRASEQLQKAVE 122 F FL+++ + + G + +G +V S DE + + + ++L+++VE Sbjct: 201 FITFLVSRSILIPLNQLKIGTEKIKHGNLDFKVRAESSDEIGELCDAFDSMRKKLKESVE 260 Query: 123 RGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQRLE 182 E+++ +L+ N++HD++TP+TS+ GY++ I + T E+++ Y Y K+Q + Sbjct: 261 LQAQYENNRKELISNISHDLKTPITSIKGYIEGIRDGVADTPEKMEKYVNTIYNKTQSMN 320 Query: 183 KLIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKL--TSRLQITPQMVI 240 LIEEL ++++ L +D + L EE EKN + + I + + Sbjct: 321 YLIEELLTYSKLDLKKLPFYFIDMDFVSYMNDLMEEFKFDVEKNNMEFSYDNHIKGKANV 380 Query: 241 PADGELLARVFENLLTNAARY-GRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLF 299 D + + RV N+++N+ +Y ++ + + +V I + G I E LP++F Sbjct: 381 RIDVQNINRVISNIISNSIKYMDKEHGKISVEVDSNNEEVLVGIKDNGMGISEEALPYVF 440 Query: 300 DMFYTGDRARTSDANSTGLGLFIAKNIVEQHGGTISAESSV---TRTLFEVRL 349 D FY D +R + +GLGL I K I+E+HGG+I A+S T F ++L Sbjct: 441 DRFYREDFSRNTSKGGSGLGLAICKKIIEEHGGSIWAKSQKGHGTEIWFSIKL 493 >lin1543 [T] COG0642 Signal transduction histidine kinase Length = 182 Score = 123 bits (308), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 0/312 (0%), Positives = 0/312 (0%), Gaps = 12/312 (3%) Query: 47 IGDVN----FFLILFVPLAIFFFFLLTKRYAAYFDTISSGIHNLANGEFSSRVEITSHDE 102 Sbjct: 165 QATNREARK 224 Query: 103 FQVIAEDINRASEQLQKAVERGDFAESSKDQLVLNLAHDIRTPLTSVLGYLDYILNHTDL 162 Sbjct: 225 284 Query: 163 TAEQVKHYTMIAYTKSQRLEKLIEELFEITRVNYGMLAVVKAPIDLSELLFQLNEEL-YP 221 Sbjct: 285 - 343 Query: 222 LFEK-NKLTSRLQITPQMVIPADGELLARVFENLLTNAARYGRDGQFVDIHCRHEGGSAV 280 Sbjct: 344 --- 400 Query: 281 VQIINYGNFIPAEELPFLFDMFYTGDRARTSDA-NSTGLGLFIAKNIVEQHGGTISAESS 339 Sbjct: 401 460 Query: 340 VTR-TLFEVRLP 350 Sbjct: 461 472 >SA1322 [T] COG0642 Signal transduction histidine kinase Length = 588 Score = 115 bits (289), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 67/221 (30%), Positives = 116/221 (52%), Gaps = 1/221 (0%) Query: 131 KDQLVLNLAHDIRTPLTSVLGYLDYILNHTDLTAEQVKHYTMIAYTKSQRLEKLIEELFE 190 K + N++H++RTP++ + GY + I++ +++K + +S+RL +L+ EL Sbjct: 365 KKDFIANVSHELRTPISLLQGYTESIVDGIVTEPDEIKESLAVVLDESKRLNRLVNELLN 424 Query: 191 ITRVNYGMLAVVKAPIDLSELLFQLNEELYPLFEKNKLTSRLQITPQMVIPADGELLARV 250 + R++ L+V K ++ LL ++ + + L + V D + + +V Sbjct: 425 VARMDAEGLSVNKEVQPIAALLDKMKIKYRQQADDLGLNMTFNYCKKRVWSYDMDRMDQV 484 Query: 251 FENLLTNAARYGRDGQFVDIHCRHEGGSAVVQIINYGNFIPAEELPFLFDMFYTGDRART 310 NL+ NA+RY + G + I C ++ I + G I E L +FD FY D ART Sbjct: 485 LTNLIDNASRYTKPGDEIAITCDENESEDILYIKDTGTGIAPEHLQQVFDRFYKVDAART 544 Query: 311 SDANSTGLGLFIAKNIVEQHGGTISAESSVTR-TLFEVRLP 350 TGLGLFI K I+E+HGG+I +S + + T F ++LP Sbjct: 545 RGKQGTGLGLFICKMIIEEHGGSIDVKSELGKGTTFIIKLP 585 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.324 0.140 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 23,816,018 Number of extensions: 985914 Number of successful extensions: 4034 Number of sequences better than 1.0e-05: 221 Number of HSP's gapped: 3798 Number of HSP's successfully gapped: 221 Length of query: 353 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 246 Effective length of database: 26,037,693 Effective search space: 6405272478 Effective search space used: 6405272478 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.5 bits) S2: 116 (49.3 bits)