BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0340.0012.p
         (91 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

PA2611_2 [H] COG0007 Uroporphyrinogen-III methylase                    82   2e-16
BS_nasF_1 [H] COG0007 Uroporphyrinogen-III methylase                   75   2e-14
BS_ylnD [H] COG0007 Uroporphyrinogen-III methylase                     72   2e-13
YPO0158_2 [H] COG0007 Uroporphyrinogen-III methylase                   69   1e-12
AF1243 [H] COG0007 Uroporphyrinogen-III methylase                      68   3e-12

>PA2611_2 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score = 82.0 bits (201), Expect = 2e-16,   Method: Compositional matrix adjust.
 Identities = 0/83 (0%), Positives = 0/83 (0%)

Query: 3   TLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMKIS 62
            +                        T    I       E         +  LA A   S
Sbjct: 166 IVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLILLALARGES 225

Query: 63  NPAIIIIGESVTVRDQLLSLEKA 85
                                  
Sbjct: 226                         248


>BS_nasF_1 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score = 75.5 bits (184), Expect = 2e-14,   Method: Compositional matrix adjust.
 Identities = 0/76 (0%), Positives = 0/76 (0%)

Query: 1   VDTLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMK 60
               +  +     +     +     +      +               +        +  
Sbjct: 168 NGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLILLALARGESNP 227

Query: 61  ISNPAIIIIGESVTVR 76
                           
Sbjct: 228                  243


>BS_ylnD [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score = 71.6 bits (174), Expect = 2e-13,   Method: Compositional matrix adjust.
 Identities = 0/89 (0%), Positives = 0/89 (0%)

Query: 1   VDTLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMK 60
              ++    V  L  + +   +   +                     T   +  L A  +
Sbjct: 163 SVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLILLALAR 222

Query: 61  ISNPAIIIIGESVTVRDQLLSLEKAVRSQ 89
                                        
Sbjct: 223                               251


>YPO0158_2 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score = 69.3 bits (168), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 0/77 (0%), Positives = 0/77 (0%), Gaps = 2/77 (2%)

Query: 3   TLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMKIS 62
            +     V   A   +  +   +D                      L  + R        
Sbjct: 171 AVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLILLALARG--ESNPL 228

Query: 63  NPAIIIIGESVTVRDQL 79
                            
Sbjct: 229                   245


>AF1243 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score = 68.2 bits (165), Expect = 3e-12,   Method: Compositional matrix adjust.
 Identities = 0/71 (0%), Positives = 0/71 (0%)

Query: 3   TLIIYMGVSTLAEIREQLLKHGKDPATPAALIENGTTVRERAVTGTLGNIDRLAAAMKIS 62
           ++ I  G +       +      D             V+  A      + + L       
Sbjct: 163 SVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLILLALAR 222

Query: 63  NPAIIIIGESV 73
                      
Sbjct: 223             233


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.316    0.133    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 6,148,950
Number of extensions: 199357
Number of successful extensions: 568
Number of sequences better than 1.0e-05: 27
Number of HSP's gapped: 561
Number of HSP's successfully gapped: 27
Length of query: 91
Length of database: 38,378,431
Length adjustment: 61
Effective length of query: 30
Effective length of database: 31,343,057
Effective search space: 940291710
Effective search space used: 940291710
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 109 (46.6 bits)