BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0340.0011.p
         (171 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BS_ylnD [H] COG0007 Uroporphyrinogen-III methylase                    139   3e-33
aq_2071 [R] COG1092 Predicted SAM-dependent methyltransferases        139   3e-33
YPO0158_2 [H] COG0007 Uroporphyrinogen-III methylase                  123   2e-28
PA2611_2 [H] COG0007 Uroporphyrinogen-III methylase                   120   8e-28
BS_nasF_1 [H] COG0007 Uroporphyrinogen-III methylase                  120   9e-28

>BS_ylnD [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score =  139 bits (349), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 9/143 (6%), Positives = 17/143 (11%)

Query: 4   GSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGRH 63
                         L          +  V   D  V                 G+     
Sbjct: 2   RPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITA 61

Query: 64  SMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXXX 123
                           A       +  +                      +         
Sbjct: 62  EYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQA 121

Query: 124 XXXXXXXPLTHRGLAASFAIVTG 146
                   +T   +A   A+   
Sbjct: 122 DGGTRTASITGACVALVDALQKL 144


>aq_2071 [R] COG1092 Predicted SAM-dependent methyltransferases
          Length = 244

 Score =  139 bits (349), Expect = 3e-33,   Method: Compositional matrix adjust.
 Identities = 68/143 (47%), Positives = 93/143 (65%)

Query: 4   GSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGRH 63
           G V ++GAGPGDPELLT+KA R ++ ADV+LYD LVN EIL   + ++L+IY GK  G+H
Sbjct: 2   GKVYLIGAGPGDPELLTLKAYRILRKADVVLYDALVNREILHFARQDSLKIYVGKRDGKH 61

Query: 64  SMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXXX 123
           S+PQE I +L+ ++A +   VVRLKGGDP++F                  ++PGIT    
Sbjct: 62  SLPQEEINELLHRFALSYKIVVRLKGGDPFVFGRGGEELLYLKSRGVEVEIVPGITSAIS 121

Query: 124 XXXXXXXPLTHRGLAASFAIVTG 146
                  P+THRG+A+SFA+VTG
Sbjct: 122 APSSAFIPVTHRGIASSFAVVTG 144


>YPO0158_2 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score =  123 bits (308), Expect = 2e-28,   Method: Compositional matrix adjust.
 Identities = 10/144 (6%), Positives = 20/144 (13%)

Query: 3   QGSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGR 62
                +               V    T  +              G+ +           R
Sbjct: 9   NQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPR 68

Query: 63  HSMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXX 122
            +  +   E    K      ++ RL                             G T   
Sbjct: 69  STHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTA 128

Query: 123 XXXXXXXXPLTHRGLAASFAIVTG 146
                    +           +  
Sbjct: 129 SITGACVALVDALQKLVENGKLKT 152


>PA2611_2 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score =  120 bits (302), Expect = 8e-28,   Method: Compositional matrix adjust.
 Identities = 13/143 (9%), Positives = 21/143 (14%)

Query: 4   GSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAPGRH 63
              S     P        K        +      L    I             G     +
Sbjct: 4   AGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEY 63

Query: 64  SMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITXXXX 123
            M          + AA G Q  R       +                   +   +     
Sbjct: 64  GMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADG 123

Query: 124 XXXXXXXPLTHRGLAASFAIVTG 146
                        L  +   +  
Sbjct: 124 GTRTASITGACVALVDALQKLVE 146


>BS_nasF_1 [H] COG0007 Uroporphyrinogen-III methylase
          Length = 228

 Score =  120 bits (302), Expect = 9e-28,   Method: Compositional matrix adjust.
 Identities = 6/146 (4%), Positives = 11/146 (7%)

Query: 1   MIQGSVSIVGAGPGDPELLTVKAVRRIQTADVILYDRLVNEEILGCGKPEALRIYCGKAP 60
               S + V                 +            + E       +        A 
Sbjct: 3   PAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAE 62

Query: 61  GRHSMPQEGIEKLMIKYAAAGNQVVRLKGGDPYMFXXXXXXXXXXXXXXXXXXVIPGITX 120
                                                                       
Sbjct: 63  YGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQAD 122

Query: 121 XXXXXXXXXXPLTHRGLAASFAIVTG 146
                            A    +  G
Sbjct: 123 GGTRTASITGACVALVDALQKLVENG 148


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.323    0.141    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 10,775,848
Number of extensions: 362424
Number of successful extensions: 590
Number of sequences better than 1.0e-05: 39
Number of HSP's gapped: 547
Number of HSP's successfully gapped: 39
Length of query: 171
Length of database: 38,378,431
Length adjustment: 99
Effective length of query: 72
Effective length of database: 26,960,365
Effective search space: 1941146280
Effective search space used: 1941146280
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 112 (47.8 bits)