BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0340.0003.p
         (134 letters)

Database: COG 
           115,334 sequences; 38,378,431 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

CC1346 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...    79   1e-15
PA3470 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...    61   6e-10
AGc4330 [LR] COG0494 NTP pyrophosphohydrolases including oxidati...    58   4e-09
SA2278 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...    54   8e-08
SA0425 [LR] COG0494 NTP pyrophosphohydrolases including oxidativ...    53   1e-07

>CC1346 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 79.3 bits (194), Expect = 1e-15,   Method: Compositional matrix adjust.
 Identities = 7/133 (5%), Positives = 25/133 (18%), Gaps = 7/133 (5%)

Query: 2   MNGIIDKVAWIVI-SDGRVLGARSKGKDTYYFPGGKRESGETDVQTLIREVKEELSVDIL 60
           M     +   +   +   ++ A +    T                          +    
Sbjct: 1   MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60

Query: 61  SGTVKPFGIFEAAAHGKAEGVQVKMACFTADYTGELTPASEIAEIAWL---AYEDRERVS 117
                   + +     +A    +     T          + +   A        D+  + 
Sbjct: 61  REMK--ERVGQTLGRKEA-RGLMISTFHTLGLDIIKREYAALGMKANFSLFDDTDQLALL 117

Query: 118 AVSRMVFDQLHEL 130
                   +  ++
Sbjct: 118 KELTEGLIEDDKV 130


>PA3470 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 60.8 bits (146), Expect = 6e-10,   Method: Compositional matrix adjust.
 Identities = 9/109 (8%), Positives = 16/109 (14%), Gaps = 2/109 (1%)

Query: 1   MMNGIIDKVAWIVISD-GRVLGARSKGKDTYYFPGGKRESGETDVQTLIREVKEELSVDI 59
           M      + A   ++    VL     GK                 Q          +   
Sbjct: 1   MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60

Query: 60  LSGTVKPFGIFEAAAHGKAEGVQVKMACFTADYTGELTPASEIAEIAWL 108
                +               +             E       A  +  
Sbjct: 61  REMKERVGQTLGRKEARGL-MISTFHTLGLDIIKREYAALGMKANFSLF 108


>AGc4330 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 57.8 bits (138), Expect = 4e-09,   Method: Compositional matrix adjust.
 Identities = 3/100 (3%), Positives = 11/100 (11%), Gaps = 2/100 (2%)

Query: 10  AWIVISDGR-VLGARSKGKDTYYFPGGKRESGETDVQTLIREVKEELSVDILSGTVKPFG 68
               +       G      +               +  +    K    +    G      
Sbjct: 15  TGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGRK 74

Query: 69  IFEAAAHGKAEGVQVKMACFTADYTGELTPASEIAEIAWL 108
                                      +     + +    
Sbjct: 75  EARGLMISTF-HTLGLDIIKREYAALGMKANFSLFDDTDQ 113


>SA2278 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 53.5 bits (127), Expect = 8e-08,   Method: Compositional matrix adjust.
 Identities = 9/120 (7%), Positives = 23/120 (19%), Gaps = 10/120 (8%)

Query: 2   MNGIIDKVAWIVISDGRVLGARSKGKDT----YYFPGGKRESGETDVQTLIREVKEELSV 57
           M     +   +    G  L     G                      + +        + 
Sbjct: 1   MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAA 60

Query: 58  DILSGTVKPFGIFEAAAHGKAEGVQVKMACFTADYTGELTPASEIAEIAWLAYEDRERVS 117
             +        + +     +A G+ +     T          + +   A  +  D     
Sbjct: 61  REMKE-----RVGQTLGRKEARGL-MISTFHTLGLDIIKREYAALGMKANFSLFDDTDQL 114


>SA0425 [LR] COG0494 NTP pyrophosphohydrolases including oxidative damage
           repair enzymes
          Length = 673

 Score = 53.1 bits (126), Expect = 1e-07,   Method: Compositional matrix adjust.
 Identities = 6/95 (6%), Positives = 17/95 (17%), Gaps = 6/95 (6%)

Query: 18  RVLGARSKGKDTYYFPGGKRESGETDVQTLIREVKEELSVDILSGTVKPFGIFEAAAHGK 77
                                     ++    + +   +V   +   +          G+
Sbjct: 14  VTGPCLVLAGAGSGKTRVITNKIAHLIRGCGYQARHIAAVTFTNKAAREMKERVGQTLGR 73

Query: 78  AEGVQVKMACFTA----DYTGELTPASEIAEIAWL 108
            E     M         D       A+   +  + 
Sbjct: 74  KEAR-GLMISTFHTLGLDIIK-REYAALGMKANFS 106


  Database: COG
    Posted date:  Aug 3, 2010  9:58 AM
  Number of letters in database: 38,378,431
  Number of sequences in database:  115,334
  
Lambda     K      H
   0.318    0.135    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 115334
Number of Hits to DB: 10,521,735
Number of extensions: 412900
Number of successful extensions: 1252
Number of sequences better than 1.0e-05: 9
Number of HSP's gapped: 1261
Number of HSP's successfully gapped: 9
Length of query: 134
Length of database: 38,378,431
Length adjustment: 95
Effective length of query: 39
Effective length of database: 27,421,701
Effective search space: 1069446339
Effective search space used: 1069446339
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 110 (47.0 bits)