BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0337.0011.p (253 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value lin0978 [V] COG1131 ABC-type multidrug transport system, ATPase ... 338 6e-93 ML2352 [V] COG1131 ABC-type multidrug transport system, ATPase c... 213 2e-55 PAE0269 [V] COG1131 ABC-type multidrug transport system, ATPase ... 212 5e-55 SSO2137 [V] COG1131 ABC-type multidrug transport system, ATPase ... 202 6e-52 sll0759 [V] COG1131 ABC-type multidrug transport system, ATPase ... 201 9e-52 >lin0978 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 254 Score = 338 bits (866), Expect = 6e-93, Method: Compositional matrix adjust. Identities = 175/253 (69%), Positives = 205/253 (81%) Query: 1 MQTKSIQVKGLQKSYRQLQVLKGVDFEVEKGSIFALLGSNGAGKTTVVKILSTLLKPDSG 60 M I+ GL+KS+++ +VLKGVDF V +G IFALLGSNGAGKTT ++IL+TLLK D+G Sbjct: 1 MNEWMIEASGLRKSFKKTEVLKGVDFGVRRGEIFALLGSNGAGKTTTIQILTTLLKADNG 60 Query: 61 TVSVNGFDVAAKPGDVRQSISLTGQFAAVDEILTGRENLIMIARLRHLDHPRQVADDLLR 120 SV G DV +P VR+ ISLTGQFAAVD +LTGREN+++IA+LR +P Q A DLL Sbjct: 61 KASVAGLDVTKEPEKVREHISLTGQFAAVDGLLTGRENILLIAKLRGEKNPDQTAKDLLA 120 Query: 121 RFGLTDAADRKASVYSGGMRRRLDIAMSLVGKPQLIFLDEPTTGLDPEARIEAWKIVKEL 180 RFGL A+DR+A YSGGM RRLDIAMSLVG P +IFLDEPTTGLDPE RIE WK +K L Sbjct: 121 RFGLEKASDRRADTYSGGMMRRLDIAMSLVGSPDVIFLDEPTTGLDPEGRIEVWKTIKAL 180 Query: 181 ADGGTTVFLTTQYLEEAEQLADRIAILHEGRIIASGTLAELKKLFPSAKVEYVEKQPTLE 240 +DGGTT+ LTTQYL+EAEQLADRIAILH G IIA+GTL ELKKLFP A++EYVEKQP+LE Sbjct: 181 SDGGTTILLTTQYLDEAEQLADRIAILHGGTIIANGTLEELKKLFPPAEIEYVEKQPSLE 240 Query: 241 EIFLAIIGKKEAV 253 EIFLAII KE V Sbjct: 241 EIFLAIINGKEGV 253 >ML2352 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 311 Score = 213 bits (542), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 14/236 (5%), Positives = 49/236 (20%), Gaps = 4/236 (1%) Query: 4 KSIQVKGLQKSYRQLQV--LKGVDFEVEKGSIFALLGSNGAGKTTVVKILSTLLKPDSGT 61 ++ L+ R + + + L I + + Sbjct: 6 FKHLLESLKNLKRNGWMTVAAVSSVTITLVLVGLFLSVILNTSKISNGIENNVRIVAYMK 65 Query: 62 VSVNGFDVAAKPGDVRQSISLTGQFAAVDEILTGRENLIMIARLRHLDHP--RQVADDLL 119 + V+ + + + + + + N+ + A Sbjct: 66 LDVHDQETKIQDPKDNKKTINNPDHLKIYDSIKKVPNVKTVEFSSKEAQLKELTKALGNN 125 Query: 120 RRFGLTDAADRKASVYSGGMRRRLDIAMSLVGKPQLIFLDEPTTGLDPEARIEAWKIVKE 179 DA + + +++ G + + + ++ Sbjct: 126 WNLFKGDANPLYDAYIVEADKPANVKSVTSKISKLSGIEKATYGGANTAKLFQIAQGIRT 185 Query: 180 LADGGTTVFLTTQYLEEAEQLADRIAILHEGRIIASGTLAELKKLFPSAKVEYVEK 235 + + + + I I A+ + +E Sbjct: 186 WGTAAAILLIFVAVFLISNTIRITILSRQREIQIMRLVGAKNGYIRWPFFLEGAWV 241 >PAE0269 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 317 Score = 212 bits (539), Expect = 5e-55, Method: Compositional matrix adjust. Identities = 110/234 (47%), Positives = 157/234 (67%), Gaps = 1/234 (0%) Query: 5 SIQVKGLQKSYRQLQVLKGVDFEVEKGSIFALLGSNGAGKTTVVKILSTLLKPDSGTVSV 64 +I V+ L K Y ++ L+G+ FEV +G +F LLG NGAGKTT +KIL+ L KP SG V Sbjct: 3 AIVVENLVKRYGDVEALRGISFEVSRGEVFGLLGPNGAGKTTTIKILTGLTKPTSGRAIV 62 Query: 65 NGFDVAAKPGDVRQSISLTGQFAAVDEILTGRENLIMIARLRHLDHPRQVADDLLRRFGL 124 GFDV + +V++SI VD+ LTG ENL + ARL + + R+ A +LLR FGL Sbjct: 63 AGFDVVKEAAEVKRSIGWIASEVIVDDELTGWENLEIQARLAGVKNWRERAAELLRYFGL 122 Query: 125 TDAADRKASVYSGGMRRRLDIAMSLVGKPQLIFLDEPTTGLDPEARIEAWKIVKEL-ADG 183 +AA+R YS GMR+RL++AM+L+ P+++F+DEPT GLD AR+ W++++++ D Sbjct: 123 AEAANRLVGKYSTGMRKRLEVAMALLHGPEILFMDEPTVGLDVGARMGLWEVIRQINKDF 182 Query: 184 GTTVFLTTQYLEEAEQLADRIAILHEGRIIASGTLAELKKLFPSAKVEYVEKQP 237 G TV LTT Y+EEAE+L RIAI+++GR++A GT ELK + VE +P Sbjct: 183 GVTVLLTTHYMEEAEELCGRIAIINKGRLVAVGTPGELKAKYGVDVVELEVSKP 236 >SSO2137 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 339 Score = 202 bits (513), Expect = 6e-52, Method: Compositional matrix adjust. Identities = 105/228 (46%), Positives = 153/228 (67%), Gaps = 7/228 (3%) Query: 1 MQTKSIQVKGLQKSYRQLQVLKGVDFEVEKGSIFALLGSNGAGKTTVVKILSTLLKPDSG 60 M+ +I+ L K + + + ++FEV +G IF LG NGAGK+T +K+L+T+LKP G Sbjct: 7 MRNVAIKAINLTKRFGKFVAVDHINFEVYEGEIFGFLGPNGAGKSTTIKMLTTVLKPSEG 66 Query: 61 TVSVNGFDVAAKPGDVRQSISLTGQFAAVDEILTGRENLIMIARLRHLDHPRQVAD---- 116 T +V+G+DV +P VRQSI + Q DE LTG EN++M+A L + P+++A+ Sbjct: 67 TATVSGYDVIKQPALVRQSIGVVPQEYTADEDLTGWENMMMMAGLYGI--PKRIAEERAK 124 Query: 117 DLLRRFGLTDAADRKASVYSGGMRRRLDIAMSLVGKPQLIFLDEPTTGLDPEARIEAWKI 176 +LL LT AA RK YSGGMRRRL+IAMSL+ +P+++FLDEPT GLD + R W+ Sbjct: 125 ELLEMVELTYAAKRKVETYSGGMRRRLEIAMSLISRPRILFLDEPTLGLDAQTRAAIWQY 184 Query: 177 VKELADG-GTTVFLTTQYLEEAEQLADRIAILHEGRIIASGTLAELKK 223 + +L + T+F+TT YLEEA+ DRIAI+ +G+I+A G+ ELK+ Sbjct: 185 IMKLKEEYKMTIFVTTHYLEEADMYGDRIAIIDKGKILAIGSPKELKE 232 >sll0759 [V] COG1131 ABC-type multidrug transport system, ATPase component Length = 347 Score = 201 bits (511), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 102/220 (46%), Positives = 146/220 (66%), Gaps = 2/220 (0%) Query: 5 SIQVKGLQKSYRQLQVLKGVDFEVEKGSIFALLGSNGAGKTTVVKILSTLLKPDSGTVSV 64 ++QVK L+K Y + +K + F V +G IF LLG NGAGKTT ++ L TL KPD G + + Sbjct: 10 AVQVKQLRKKYGAIPAVKDISFAVPRGEIFGLLGPNGAGKTTTIRCLCTLAKPDGGELWI 69 Query: 65 NGFDVAAKPGDVRQSISLTGQFAAVDEILTGRENLIMIARLRHLD--HPRQVADDLLRRF 122 +G +V + P R+ + Q A+D+ILTGRE L + A L HLD ++ D LL Sbjct: 70 DGVNVLSDPRQARRRLGYVAQEVAIDKILTGRELLQLQASLYHLDAISSQKRIDQLLDIL 129 Query: 123 GLTDAADRKASVYSGGMRRRLDIAMSLVGKPQLIFLDEPTTGLDPEARIEAWKIVKELAD 182 GLT AD+K YSGG+++RLD+A L+ +P ++ LDEP+ GLD E+R W+ +++L D Sbjct: 130 GLTAYADQKTGTYSGGLKKRLDLAAGLLHQPTVLVLDEPSVGLDIESRFILWEFLRQLRD 189 Query: 183 GGTTVFLTTQYLEEAEQLADRIAILHEGRIIASGTLAELK 222 GTTV +T+ YLEE + LADR+AI+ +G +IA+GT ELK Sbjct: 190 AGTTVVITSHYLEEIDALADRLAIIDQGTVIATGTPTELK 229 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.318 0.136 0.370 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 18,245,115 Number of extensions: 767479 Number of successful extensions: 9971 Number of sequences better than 1.0e-05: 2146 Number of HSP's gapped: 7146 Number of HSP's successfully gapped: 2405 Length of query: 253 Length of database: 38,378,431 Length adjustment: 104 Effective length of query: 149 Effective length of database: 26,383,695 Effective search space: 3931170555 Effective search space used: 3931170555 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 114 (48.5 bits)