BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0335.0006.p (337 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMb20965 [V] COG1680 Beta-lactamase class C and other penicillin... 132 7e-31 lin1811 [V] COG1680 Beta-lactamase class C and other penicillin ... 129 5e-30 AGc3509 [V] COG1680 Beta-lactamase class C and other penicillin ... 112 1e-24 PA4347 [V] COG1680 Beta-lactamase class C and other penicillin b... 102 9e-22 CC0869 [V] COG1680 Beta-lactamase class C and other penicillin b... 100 5e-21 >SMb20965 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 132 bits (332), Expect = 7e-31, Method: Compositional matrix adjust. Identities = 0/292 (0%), Positives = 0/292 (0%), Gaps = 36/292 (12%) Query: 29 LRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMDQGLLPDPSSSVAEF 88 ST + + + +S L + D + F Sbjct: 39 GCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIF 98 Query: 89 FPQ-LRRDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPKMTRSPDWVEYVLEQPLXXX 147 L+ D + L LL + N + + T + Sbjct: 99 ANASLQWLPDHYELFPHLVSLLNPQGVL--AVQMPDN-WLEPTHVLMREVAWEQNYPD-- 153 Query: 148 XADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIEEYQWEADPQGIHTG 207 ++ L A TT + T Sbjct: 154 --RGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTE 211 Query: 208 GFGLQLRPSALLKFGQLYLQQGRW-NGAQLIS--------RERLARSVTTAMHAEAPRRG 258 + Y Q Sbjct: 212 SEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFIVARRM--------- 262 Query: 259 GYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQD 310 Sbjct: 263 ---------- 304 >lin1811 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 129 bits (325), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 0/299 (0%), Positives = 0/299 (0%), Gaps = 41/299 (13%) Query: 28 NLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMDQGLLPDPSSSVAE 87 + + + SS IA + LPD A+ Sbjct: 25 ARVPLENVEYVADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEAD 84 Query: 88 FFPQLR-RDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPKMTRSPDWVEYVLEQPLXX 146 + D +L+ L F + + ++ Sbjct: 85 IRNWQPVQALDLIFANASLQWLPDHYELFPHLVSL--LNPQGVLAVQMPDNWLEP---TH 139 Query: 147 XXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIEEY----------- 195 + + A + + + E ++ + Sbjct: 140 VLMREVAW-EQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVT 198 Query: 196 -------QWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTT 248 Sbjct: 199 ATGLRPW 258 Query: 249 AMHAEAPRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVL 307 Sbjct: 259 ---------------- 301 >AGc3509 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 112 bits (279), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 0/299 (0%), Positives = 0/299 (0%), Gaps = 36/299 (12%) Query: 20 LQHAIAPLNLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMDQGLLP 79 + + + A Sbjct: 147 WEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWL 206 Query: 80 DPSSSVAEFFPQLRRD----KDTRKQEITLEHLLTLSAGFRWSEFGGLNSFPKMTRSPDW 135 + + L + + + L+ Sbjct: 207 QDLTESEQQ---LFLKRYHQMLEEQYPLQENGQILLAFPRL--FIVARR- 260 Query: 136 VEYVLEQPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPL-GIEE 194 Sbjct: 261 ----- 315 Query: 195 YQWEADPQGIHTGGFGLQLRPSALLKFGQLYLQQGRW-NGAQLISRERLARS----VTTA 249 Sbjct: 316 375 Query: 250 MHAEAPRRGGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLT 308 Sbjct: 376 --------------- 419 >PA4347 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 102 bits (254), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 0/298 (0%), Positives = 0/298 (0%), Gaps = 25/298 (8%) Query: 31 SCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMDQGL--LPDPSSSVAEF 88 + + + D A+ + + L+ + QG+ + P Sbjct: 79 QFVEADIRNWQPVQALDLIFANASLQWLPDHYELFPHLVSLLNPQGVLAVQMP---DNWL 135 Query: 89 FPQLRRDKDTRKQEITLEHLLTLSAGFRWSE---FGGLNSFPKM---TRS-PDWVEYVLE 141 P +E+ E + + + S + + Sbjct: 136 EPTH-----VLMREVAWEQNYPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSH 190 Query: 142 QPLXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIEEYQWEADP 201 Q D S + + L I Sbjct: 191 QA----IIDWVTATGLRPWLQDLTESEQQLFLKRYHQMLEEQYPLQENGQILLAFPRLFI 246 Query: 202 QGIHTGGFGLQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTTAMH----AEAPRR 257 Sbjct: 247 306 Query: 258 GGYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQDNKRGK 315 Sbjct: 307 364 >CC0869 [V] COG1680 Beta-lactamase class C and other penicillin binding proteins Length = 252 Score = 100 bits (248), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 0/291 (0%), Positives = 0/291 (0%), Gaps = 25/291 (8%) Query: 28 NLRSCLISTRGELRFEHYRDDRTASGIAKINSCTKSVLSSLICIAMDQGLLPDPSSSVAE 87 C L + + R + ++ + C ++ + + Sbjct: 36 ADLGCGPGNSTALLQQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALD 95 Query: 88 FFPQLRRDKDTRKQEITLEHLLTLSAGFRWSEFGGLNSFP----KMTRSPDWVEYVLEQP 143 + E L + + G L E EQ Sbjct: 96 LIFAN---ASLQWLPDHYELFPHLVSLL--NPQGVLAVQMPDNWLEPTHVLMREVAWEQN 150 Query: 144 LXXXXADAPGTRMEYNSGISQLLSAILVQASGMTTARFAEQYLFGPLGIEEYQWEADPQG 203 D + +LS + T + + + P Sbjct: 151 ----YPDRGREPLAGVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWL 206 Query: 204 IHTGGFG-LQLRPSALLKFGQLYLQQGRWNGAQLISRERLARSVTTAMH----AEAPRRG 258 Sbjct: 207 -QDLTESE 265 Query: 259 GYGWHWWTDSYPHAASDGEPPAAMQFYYARGYAGQFVYVLPEPQTVVVLTQ 309 Sbjct: 266 ------ 310 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.134 0.419 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 25,272,552 Number of extensions: 1015329 Number of successful extensions: 1410 Number of sequences better than 1.0e-05: 16 Number of HSP's gapped: 1390 Number of HSP's successfully gapped: 16 Length of query: 337 Length of database: 38,378,431 Length adjustment: 107 Effective length of query: 230 Effective length of database: 26,037,693 Effective search space: 5988669390 Effective search space used: 5988669390 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 116 (49.3 bits)