BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0334.0007.p (535 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BH1123 [T] COG4753 Response regulator containing CheY-like recei... 151 3e-36 BH2109 [T] COG4753 Response regulator containing CheY-like recei... 147 5e-35 BH2728 [T] COG4753 Response regulator containing CheY-like recei... 100 5e-21 BH1910 [T] COG4753 Response regulator containing CheY-like recei... 100 5e-21 SPy1587 [T] COG4753 Response regulator containing CheY-like rece... 97 8e-20 >BH1123 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 526 Score = 151 bits (381), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 141/550 (25%), Positives = 247/550 (44%), Gaps = 59/550 (10%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 MWK+V+IDD+ ++RGL + I W+ G E A +G GLD V PH+V+TDI MP Sbjct: 1 MWKVVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRETSPHIVLTDIYMPI 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 M GL + + ++ D ++++++ Y EFE A+KA++L + D++ KP D + V R Sbjct: 61 MYGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVI 120 Query: 121 AEWEQE-------RALAKKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAER 173 + E++ + L KV P + + ++LL G+ R EI E K ++ Sbjct: 121 NKLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKITKWKDQQ 180 Query: 174 YAVLLIIADDYYETGAGNR----FGQELLKYCIHNISLEVLDSLGEGVVFELGEDEI--A 227 + + D G N+ L +Y +H + EVL+ G + F E + + Sbjct: 181 HIACSLTYD-----GPQNKELKPADWYLFRYSVHKMIREVLN--GYPIDFRYLEMDAYRS 233 Query: 228 VIC---TGSADQQAMERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAK 284 +C S + + +M++ + + TV G V + T +++S+HEA Sbjct: 234 ALCLHVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSESFHEAC 293 Query: 285 AATDFRHIAGTNQVLSFRDTKVKQHVSGHPAVNGGWEADLGMN--------IRLGFVQEA 336 + SF G+P +G A M IR A Sbjct: 294 MESQ-----------SFP--------LGNPYEDGT-RATFPMESSQKLYDAIRYADATRA 333 Query: 337 LLVLEHMEKQIQSAPITLERLRLLGIEIVLVIVNTFQSWSEPPYDRERVEE---LLQELP 393 VLE + P + +GIEI +I T+ + +E +E L Q L Sbjct: 334 KEVLEEAVGVLGEVPYSTLVGYKVGIEIWTII--TYSLYDIGILIQEMFDEDFDLAQHLT 391 Query: 394 KIRTAKDIFQNLRALIRDAAAGVNDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQV 453 K ++ + L I + + K+ ++Q + YI K ++ E ++LQD+AD++ Sbjct: 392 KQGNWQEWIRFLCEQIEHICYHQQWDENIKHKQLIEQVMIYIEK-HLAENITLQDIADEL 450 Query: 454 HLSTSYFSMIFKKQTGTTFSEFLQDVRMKKAVELLR-GEEMXXXXSSQPGRIHQSAAFQR 512 ++S +Y IFKK G +F ++ +RM+KA ++++ G + S + G ++ A F Sbjct: 451 YISRNYLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVN-PAYFTT 509 Query: 513 PFQETYRQNP 522 F++ P Sbjct: 510 MFKKYTGYTP 519 >BH2109 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 525 Score = 147 bits (370), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 125/527 (23%), Positives = 239/527 (45%), Gaps = 14/527 (2%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+K++L DD+ + GL I WE+ G+EV+A A +GE+ V+ +P +VITDIRMP Sbjct: 1 MYKVLLADDEFFVRHGLKSLIEWEKCGYEVAAEADNGEDAFKLVQEIKPDLVITDIRMPV 60 Query: 61 MDGLQLTEAIKSKFP-DVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRA 119 DGLQL + + + K I+++ Y++F +AQKA++ DFVLKP++ D+L ++ Sbjct: 61 FDGLQLIQKVNETLSFNTKFIIISGYNDFSYAQKAVRFGAVDFVLKPIDQDELEAALIKL 120 Query: 120 AAEWEQERALA---KKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAERYAV 176 AA +QE+A +KVL L Q F +L K ++ E+ A L + + Y + Sbjct: 121 AATLDQEKATNSDQEKVL-----LDQIFIHSLGENK-KENEVRRWAAKLNINNRHFYYYL 174 Query: 177 LLIIADDYYETGAGNRFGQELLKYCIHNISLEVLDSLGEGVVFELGEDEIAVICTGSADQ 236 LL + + + G N +E ++ I + ++E + ++ T S Sbjct: 175 LLEVNNLSLDKGFINEQYKEPIRKVIRETVARQAATEEYTAIYEQLDHAYGLLIT-SEHL 233 Query: 237 QAMERKVMQMAEHIRYNAEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRHIAGTN 296 + ++ +AE +R + + + +TV G +L+ I +SY A + ++++I Sbjct: 234 KKFNGQIEPLAEKLRKDIQDFTNIPLTVYVGAKTDDLSTIKKSYETANSLRNYKYIFNEK 293 Query: 297 QVLSFRDTKVKQHVSGHPAVNGGWEADLGMNIRLGFVQEALLVLEHMEKQIQSAPITLER 356 V T+ + + +N L + + +++ + + Q+ Sbjct: 294 NVFIHEQTESVD--TTYDELNNHLFVTLMEQMEENNSDRIVNIIDKIFSEFQTKKFVPSA 351 Query: 357 LRLLGIEIVLVIVNTFQSWSEPPYDRERVEELLQELPKIRTAKDIFQNLRALIRDAAAGV 416 ++ V ++ T Q+ + + T + Q + +AA + Sbjct: 352 VKTSVNRCVHKVMQTVQAMEGDTGKIISAQAMTNWESYNLTFDQLKQVFTKFVLEAAVII 411 Query: 417 NDSRSTQQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKKQTGTTFSEFL 476 + R K + + YI +N+ E +SL+ +A +++ Y +FKK G F E+L Sbjct: 412 QELRKENMKSDIYKVKTYI-ENHYHENISLKSIASLFYMNPVYMGQLFKKTFGVYFKEYL 470 Query: 477 QDVRMKKAVELLRGEEMXXXXSSQPGRIHQSAAFQRPFQETYRQNPV 523 +RM +A +LLR +M ++ + F F++ + P Sbjct: 471 LKLRMNEAKKLLRQTDMRVYEVAERVGFGSTDYFVTQFEKINKMTPT 517 >BH2728 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 510 Score = 100 bits (250), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 54/154 (35%), Positives = 94/154 (61%), Gaps = 7/154 (4%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M ++++DD+ +I +G+ WE+ GF++ A +G++ L+ + + PH+V+TDI MP Sbjct: 1 MCNVLIVDDEKLIRQGIINFFDWEKEGFQIVGEAANGKDALELISKNEPHIVMTDIVMPV 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 MDG+ L + +K FP+V+II+++S++EFE+ + V D++LKP N+K L L+ Sbjct: 61 MDGIDLVKRVKRDFPEVEIIVLSSFEEFEYVRSTFHSGVADYILKPRLNEKDL---LKTL 117 Query: 121 AEWEQE-RALAK--KVLEGVPFLRQRFYENLLRG 151 +E + ALAK VP + +F E +L G Sbjct: 118 SEVRGKIPALAKVDSPSRAVPSISDQF-EKILNG 150 >BH1910 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 506 Score = 100 bits (250), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 116/498 (23%), Positives = 221/498 (44%), Gaps = 48/498 (9%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+ ++++DD+ ++ GL I WEEYGF V +A +G+EG + P ++I DIRMP Sbjct: 1 MYDVMIVDDEAMVREGLKALISWEEYGFRVIDTARNGKEGFTKYRQLSPDLMIVDIRMPE 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 +DGL L E+I+++ + I+++ + +F +A+KAL + D++LKP++ D+L++ + Sbjct: 61 VDGLSLIESIRAEDSAIHFIILSGHSDFNYAKKALGCQCDDYLLKPLDEDELIDSLKKVY 120 Query: 121 AEWEQERALAKKVLEGVPFLRQRFYENLLRGKYRQEEIDHELAFLELPLKAERYAVLLII 180 + +V E V ++++ E +L E+ E+P+ E Sbjct: 121 GRITRHH----QVHELVERVQEKQVEMVL------TELLEGTPLSEIPIGKEHN----FF 166 Query: 181 ADDYYETGAGNRFGQELLKYCIHNISLEVLDSLGEGVVFELGEDEIAVICTGSADQQAME 240 A DY NR Q+ L + + ++ EG V E I ++C Sbjct: 167 ATDYQVALVENR--QDRLTKQLKRL----IEEQEEGYVIPFPE-YIVIVCKN-------- 211 Query: 241 RKVMQMAEHIRYN--AEVYLKTTVTVGTGPVCSELTGIAQSYHEAKAATDFRHIAGTNQV 298 R + + + RY+ A+ + + G L I +SY AK + + ++ Sbjct: 212 RFLQKRGKDHRYHLFAKWLEEEELHACAGSKVVNLADIYESYQSAKRLYEKKFFVEKGRL 271 Query: 299 LSFRDTKVKQHVSGHPAVNGGWEAD-LGMNIRLGFVQEALLVLEHMEKQIQSAPITLERL 357 + D V + P + AD L +I +G ++ + ++E ++ + + L+ Sbjct: 272 FT-ADQLVDRSKPEAPEFSLESYADRLYYSIDIGNMEGCVAIIEELKNVV---IVHLQEE 327 Query: 358 RLLGIEIVLVIVNTFQSWSEPPYDRERVEELLQELPKIRTAKDIFQ-----NLRALIRDA 412 + + + + + N + E V E P + A DI+Q + A + Sbjct: 328 KEIKVALFQLYSNILHQLVRSHPNMEGVLE-----PLVMNAGDIYQFEHLPGIMAFLTKQ 382 Query: 413 AAGVNDSRST-QQKRQVDQAVDYILKNYMKEGLSLQDVADQVHLSTSYFSMIFKKQTGTT 471 V D Q + + + I K+Y K L L+ +A + + +Y +FK TG Sbjct: 383 LKYVIDCMDNGQPDLLLRKMIALIHKDYAK-NLRLETLASVFNYNRAYLGKLFKNYTGEY 441 Query: 472 FSEFLQDVRMKKAVELLR 489 F+ +L VR++ LL+ Sbjct: 442 FNTYLDKVRIENGKRLLQ 459 >SPy1587 [T] COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Length = 494 Score = 96.7 bits (239), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 45/123 (36%), Positives = 81/123 (65%), Gaps = 1/123 (0%) Query: 1 MWKLVLIDDDHIILRGLSRNIPWEEYGFEVSASAHDGEEGLDAVERERPHVVITDIRMPF 60 M+K++L+DD+++IL+GL+ I W+ GFEV +A G+E L + + V+I+D+ MP Sbjct: 1 MYKVLLVDDEYMILQGLTMIIDWQALGFEVVQTARSGKEALAYLTQYPVDVMISDVTMPG 60 Query: 61 MDGLQLTEAIKSKFPDVKIILMTSYDEFEFAQKALKLKVFDFVLKPVENDKLLEVALRAA 120 M GL L EA K+ P ++ ++++ Y EF + QKA++L+ ++LKPV+ + L+ ++ Sbjct: 61 MTGLDLIEAAKTYHPQLQTLILSGYQEFSYVQKAMELETKGYLLKPVDKAE-LQAKMKQF 119 Query: 121 AEW 123 +W Sbjct: 120 KDW 122 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.319 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 37,475,934 Number of extensions: 1603563 Number of successful extensions: 4847 Number of sequences better than 1.0e-05: 269 Number of HSP's gapped: 4943 Number of HSP's successfully gapped: 273 Length of query: 535 Length of database: 38,378,431 Length adjustment: 111 Effective length of query: 424 Effective length of database: 25,576,357 Effective search space: 10844375368 Effective search space used: 10844375368 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 118 (50.1 bits)