BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0334.0002.p (207 letters) Database: COG 115,334 sequences; 38,378,431 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value DR0987 [TK] COG2197 Response regulator containing a CheY-like re... 124 1e-28 CAC3429 [TK] COG2197 Response regulator containing a CheY-like r... 114 8e-26 BMEI1582 [TK] COG2197 Response regulator containing a CheY-like ... 110 1e-24 VC1277 [TK] COG2197 Response regulator containing a CheY-like re... 102 3e-22 CAC1455 [TK] COG2197 Response regulator containing a CheY-like r... 100 2e-21 >DR0987 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 239 Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 78/215 (36%), Positives = 111/215 (51%), Gaps = 13/215 (6%) Query: 5 IRVILIDDHPLVMDSLRARLEQEQDIRVIEAFADPRHLLEQIGVLKPDVLVLDVSLPHLD 64 I ++L+DDHP+V R LE E D+RV+ L Q L PDV+++DVS+P ++ Sbjct: 26 ITLLLVDDHPVVRKGTRELLEGETDLRVVGEAGSGEEALAQARSLTPDVILMDVSMPGMN 85 Query: 65 GFSLAKLLKKDYGSSLKIIMLSGYTYDEFYRKAYELGVNAYLSKQASYAQIINAIRQSMS 124 G K +K + S+ +++L+ Y D + E G YL K AS ++ A+R + Sbjct: 86 GIEATKAIKAEQ-PSVGVLVLTSYDDDAYVFALLEAGAAGYLLKNASEDDLLGAVRAVAA 144 Query: 125 G----HLLVPERIFN--------TSAQDKLTPVEREVLLRVAREMNNREIARDLAISQRT 172 G H + ++ T +D L+P E EVL A N+EIARDL IS RT Sbjct: 145 GESALHPSIARKVLERFSVASTPTPPEDDLSPRELEVLRVAASGRTNKEIARDLDISPRT 204 Query: 173 VEYHLTAILQKLGVKSRVGAVAKGYELGVLGPSLL 207 V+ HL I KLGV SR AV G + G + P L Sbjct: 205 VQVHLANIFSKLGVGSRTEAVLHGIKRGWIDPRTL 239 >CAC3429 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 217 Score = 114 bits (286), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 71/210 (33%), Positives = 111/210 (52%), Gaps = 14/210 (6%) Query: 6 RVILIDDHPLVMDSLRARLEQEQDIRVIEAFADPRHLLEQIGVLKPDVLVLDVSLPHLDG 65 R++++DDH +V + L+ E E + V+ + L I LKPDV+++D+S+P + G Sbjct: 5 RILVVDDHFVVREGLKLIFELEDEYEVVGEAENGEQALLLIDELKPDVILMDLSMPKMSG 64 Query: 66 FSLAKLLKKDYGSSLKIIMLSGYTYDEFYRKAYELGVNAYLSKQASYAQIINAIRQSMSG 125 + K LK + +S+ II+L+ Y D ++ LG YL K + ++I + + G Sbjct: 65 LDVLKALK-EKENSIPIIILTTYNEDNLIKEGLSLGAKGYLLKDTTREELIRTVESAFRG 123 Query: 126 HLLV-------------PERIFNTSAQDKLTPVEREVLLRVAREMNNREIARDLAISQRT 172 LL+ E NTS +T E +L +AR ++EIA D+ IS+RT Sbjct: 124 ELLLQPEVSKVLFNVKKKESTINTSFNASITERELFILQSIARGCKSKEIAFDMGISERT 183 Query: 173 VEYHLTAILQKLGVKSRVGAVAKGYELGVL 202 V+ HLT I KL V SR AVAK E G++ Sbjct: 184 VKAHLTNIYSKLQVSSRSEAVAKAIEKGII 213 >BMEI1582 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 213 Score = 110 bits (276), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 70/193 (36%), Positives = 109/193 (56%), Gaps = 7/193 (3%) Query: 5 IRVILIDDHPLVMDSLRARLEQEQDIRVIEAFADPRHLLEQIGVLKPDVLVLDVSLPHLD 64 IRV+L+D+HPLV+D LRA LE DI + A ++ R LE + PDV+++D+++P L+ Sbjct: 7 IRVLLVDNHPLVLDGLRAVLETYDDIDIAGAASNARVALEMALAVNPDVVLMDINMPLLN 66 Query: 65 GFSLAKLLKKDYGSSLKIIMLSGYTYDEFYRKAYELGVNAYLSKQASYAQIINAIRQSMS 124 G +L K+ +++I+MLS + E+ + G + Y+ K S +I+ AI S Sbjct: 67 GIDAIELFKRQL-PNVRILMLSMHDSREYISTSIMRGASGYILKDVSTNEIVTAIHAVAS 125 Query: 125 GHLL----VPERIFNTSAQ--DKLTPVEREVLLRVAREMNNREIARDLAISQRTVEYHLT 178 G V E + + + + L+ E +VL+ VA +NREIA L IS+ TVE H Sbjct: 126 GGTYFSSGVSEALLESGEKRSEGLSARENDVLVLVAEGGSNREIAARLGISEATVETHRK 185 Query: 179 AILQKLGVKSRVG 191 I +KLG+ S G Sbjct: 186 NIKKKLGIASTAG 198 >VC1277 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 216 Score = 102 bits (255), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 65/212 (30%), Positives = 113/212 (53%), Gaps = 11/212 (5%) Query: 1 MDDSIRVILIDDHPLVMDSLRARLEQEQDIRVIEAFADPRHLLEQIGVLKPDVLVLDVSL 60 MD IRV+++DDH +V+D ARLEQE +I V+ ++ LE + + +PDV+++DVS+ Sbjct: 5 MDKPIRVVMVDDHQVVLDGFIARLEQEPEIEVVATASNGLEALELVKLHQPDVVLMDVSM 64 Query: 61 PHLDGFSLAKLLKKDYGSSLKIIMLSGYTYDEFYRKAYELGVNAYLSKQASYAQIINAIR 120 P ++G +L+K++ + K++ML+ + E+ + + G Y+ K+ S +++ AI+ Sbjct: 65 PIMNGIEATRLIKEEVPHT-KVLMLTMHDNREYIMQVMQAGAMGYMLKEISALKMVQAIK 123 Query: 121 QSMSGHLLVPERIFNTSAQDKLTPV----------EREVLLRVAREMNNREIARDLAISQ 170 G E +T ++ PV E +L VA+ ++++IA L IS Sbjct: 124 TVHQGATYFCESTTSTLFSQEILPVANKPNPLSRREEAILRMVAQGCSSKKIATLLNISY 183 Query: 171 RTVEYHLTAILQKLGVKSRVGAVAKGYELGVL 202 RTVE H I KL + S + G+L Sbjct: 184 RTVETHRQNIKHKLDIHSTAELAQYALQHGLL 215 >CAC1455 [TK] COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Length = 225 Score = 100 bits (249), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 61/218 (27%), Positives = 114/218 (52%), Gaps = 21/218 (9%) Query: 5 IRVILIDDHPLVMDSLRARLEQEQDIRVIEAFADPRHLLEQIGVLKPDVLVLDVSLPHLD 64 I+V++ DD L+ SL+ L +DI ++ + ++E + KPDV+++DV +P +D Sbjct: 2 IKVLIADDQELIRQSLKIVLSANKDIEIVGTACNGNEVVESVRKYKPDVILMDVRMPEMD 61 Query: 65 GFSLAKLLKKDYGSSLKIIMLSGYTYDEFYRKAYELGVNAYLSKQASYAQIINAIRQSMS 124 G K++K+ Y ++KII+L+ + DE+ A + G + YL K S +++ AI ++ Sbjct: 62 GVQCTKVIKESY-PNIKIIVLTTFDDDEYIFNALKYGASGYLLKGVSMDELVRAIHTVVN 120 Query: 125 GHLLV-PE------RIFNTSAQ-------------DKLTPVEREVLLRVAREMNNREIAR 164 G ++ P+ ++F+ AQ D + E ++ V ++N+EIA+ Sbjct: 121 GGAMINPDITAKVFKLFSQMAQGDISIQAGTKKNTDDICDAEWNIIKCVGFGLSNKEIAK 180 Query: 165 DLAISQRTVEYHLTAILQKLGVKSRVGAVAKGYELGVL 202 L +S+ TV +L+ IL KL + R + GV+ Sbjct: 181 KLRLSEGTVRNYLSNILNKLNFRDRTQLAIWAVQTGVI 218 Database: COG Posted date: Aug 3, 2010 9:58 AM Number of letters in database: 38,378,431 Number of sequences in database: 115,334 Lambda K H 0.321 0.138 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 115334 Number of Hits to DB: 14,648,373 Number of extensions: 592338 Number of successful extensions: 2460 Number of sequences better than 1.0e-05: 219 Number of HSP's gapped: 2439 Number of HSP's successfully gapped: 219 Length of query: 207 Length of database: 38,378,431 Length adjustment: 102 Effective length of query: 105 Effective length of database: 26,614,363 Effective search space: 2794508115 Effective search space used: 2794508115 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 113 (48.1 bits)